Enzymes and Coenzymes

Name
Enzymes and Coenzymes
Accession Number
DBCAT000072
Description

Biological catalysts and their cofactors.

Drugs
DrugDrug Description
Dornase alfaA synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis.
AlteplaseA recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
UrokinaseA low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines.
ReteplaseA purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
AnistreplaseA form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
TenecteplaseA modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
Coagulation factor VIIa Recombinant HumanA form of recombinant human coagulation Factor VII used to treat hemophilia A and B.
Botulinum toxin type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
Collagenase clostridium histolyticumA collagenase enzyme used to promote debridement of necrotic tissue in burns and skin ulcers as well as to treat Dupuytren's contracture and Peyronie's disease.
RasburicaseA recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
ImigluceraseA form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
Drotrecogin alfaA form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
StreptokinaseA purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism.
AlgluceraseA form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
Agalsidase betaA recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
Pyridoxal phosphateA vitamin available in many formulations to correct vitamin B6 deficiency.
Tetrahydrofolic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
BiotinA B-complex vitamin found in many multivitamin products.
NADHA nutrient used in some supplement products.
LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
IdursulfaseA purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients.
Alglucosidase alfaAn acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency.
GalsulfaseA recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme.
Flavin adenine dinucleotideA coenzyme form of vitamin B2 used in clinical conditions associated with vitamin B2 deficiency.
3-Acetylpyridine Adenine DinucleotideA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves...
AlfimepraseAlfimeprase is being evaluated as a potential treatment for acute ischemic stroke, catheter occlusion (CO) and acute peripheral arterial occlusion (PAO).
DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
FibrinolysinFibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas.
PraconaseInvestigated for use/treatment in spinal cord injuries.
LanoteplaseInvestigated for use/treatment in myocardial infarction.
PegargiminaseInvestigated for use/treatment in melanoma and hepatocellular carcinoma.
AmediplaseInvestigated for use/treatment in myocardial infarction and thrombosis.
ChymopapainChymopapain is indicated for the development of chemonucleolysis which is used for the digestion of the nucleus pulposus in patients with disc herniation confirmed by myelography. A disc herniation occurs...
SacrosidaseAn enzyme replacement therapy used for the treatment of congenital sucrase-isomaltase deficiency (CSID).
Taliglucerase alfaA hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease.
OcriplasminA proteolytic enzyme used to treat symptomatic vitreomacular adhesion by dissolving the protein matrix responsible for the adhesion between the vitreous and macula.
GlucarpidaseA carboxypeptidase enzyme used to reduce plasma concentrations of methotrexate in patients with impaired renal function.
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Asfotase alfaAn enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP).
PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
ChymotrypsinA digestive enzyme supplement used as supportive therapy to manage the side effects associated with conventional chemotherapy, radiotherapy, and hormone therapy.
CobamamideAn ingredient found in a variety of supplements and vitamins.
PapainA proteolytic enzyme derived from papaya used for its anti-inflammatory properties.
TrypsinA naturally occurring proteolytic enzyme found in the digestive tract of mammals. Used clinically in combination with bromelain and rutosides in the treatment of some inflammatory conditions.
ThrombinA coagulation factor used to stop bleeding during surgery.
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Sebelipase alfaA recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency.
Rusalatide acetateChrysalin has been used in trials studying the treatment of Radius Fracture.
VonapanitaseVonapanitase is under investigation for the treatment of Chronic Kidney Disease.
Stem bromelainThe primary medical purpose for which stem bromelain (SB) is currently indicated for is the removal of eschar in adults with deep partial- and full-thickness thermal burns [FDA Label]. Besides...
Vatreptacog alfaVatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors.
MonteplaseMonteplase has been used in trials studying the treatment of Pulmonary Embolism.
KallidinogenaseNot Annotated
PepsinA protease indicated in the treatment of digestive disorders.
BrinaseNot Annotated
BromelainsA protease indicated in the treatment of inflammation and for eschar removal.
SaruplaseNot Annotated
TilactaseA beta-D-galactosidase use to treat lactose intolerance.
Ferric pyrophosphate citrateA soluble iron compound used to maintain hemoglobin levels in patients undergoing hemodialysis.
Andexanet alfaA recombinant Factor Xa used to reverse anticoagulation caused by rivaroxaban and apixaban.
SutilainSutilain was indicated, in the form of an ointment, as a biochemical debridement of second and third-degree burns, incisional traumatic and pyrogenic wounds and ulcers occurring due to peripheral vascular...
CocarboxylaseThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
HyaluronidaseAn enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
NattokinaseNattokinase is under investigation in clinical trial NCT00749801 (Efficacy and Safety of Geneferm Nattokinase).
Factor IX Complex (Human)A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy.
Thrombin alfaA platelet activating factor used to treat minor bleeding.
PegvaliaseAn enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment.
Coagulation factor VII humanA coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia.
Cerliponase alfaAn enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency.
Pancrelipase lipaseA lipase used to treat pancreatic exocrine insufficiency.
DesoxyribonucleaseDesoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into...
Hyaluronidase (human recombinant)An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Talactoferrin alfaInvestigated for use/treatment in adverse effects (chemotherapy), cancer/tumors (unspecified), diabetic foot ulcers, lung cancer, solid tumors, and ulcers.
Agalsidase alfaA recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
Coagulation Factor IX HumanA coagulation factor used to treat hemophilia B or factor IX hemophilia.
LactoferrinLactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
TyrosinaseTyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is...
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
Hyaluronidase (ovine)A purified form of sheep hyaluronidase enzyme used as an adjunct in subcutaneous rehydration therapy and to increase absorption of other drugs and radiopaque imaging agents.
LaronidaseA form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase.
Velaglucerase alfaAn enzyme replacement therapy used for the long-term treatment of for pediatric and adult patients with type 1 Gaucher disease.
Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
Vestronidase alfaA recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII.
Velmanase alfaA recombinant human lysosomal alpha-mannosidase used to treat non-neurological symptoms of mild to moderate alpha-mannosidosis.
Idursulfase betaIdursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Dipyrromethane CofactorNot Available
PlasminogenPlasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia).
Pancrelipase proteaseA lipase used to treat pancreatic exocrine insufficiency.
Pyrroloquinoline QuinoneA pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
ALTU-135Investigated for use/treatment in cystic fibrosis and pancreatic disorders.
Alkaline PhosphataseInvestigated for use/treatment in ulcerative colitis.
LatiglutenaseInvestigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous) and autoimmune diseases such as celiac disease.
Pancrelipase amylaseA lipase used to treat pancreatic exocrine insufficiency.
AviscumineCy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).
SerrapeptaseA protease indicated in the treatment of post-surgical inflammation.
HemicellulaseNot Annotated
ExebacaseExebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).
Lipoic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
Coenzyme ACoenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric...
NADPHNot Available
Nicotinamide adenine dinucleotide phosphateNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of...
BiopterinA natural product that has been considered as a growth factor for some insects. [PubChem]
NadideA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves...
ProthrombinA coagulation factor used for emergency reversal of vitamin K antagonist therapy.
Denileukin diftitoxA recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
Asparaginase Escherichia coliAn asparaginase enzyme from E. coli used as part of treatment regimens for acute lymphoblastic leukemias.
PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
PegademaseA modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.
RiboflavinA vitamin used to correct vitamin B2 deficiency.
SapropterinA cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU).
4-hydroxybenzoyl-CoANot Available
Methacrylyl-Coenzyme ANot Available
Desulfo-coenzyme ANot Available
Molybdenum cofactorAbsence of molybdenum cofactor leads to accumulation of toxic levels of sulphite and neurological damage usually leading to death within months of birth, due to the lack of active sulfite...
Myristoyl-CoaNot Available
Pyridoxine phosphateNot Available
D-threo-neopterinA pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a...
Hexanoyl-CoANot Available
6-hydroxy-FADNot Available
Octanoyl-Coenzyme ANot Available
Propanoyl-CoANot Available
Acetoacetyl-CoANot Available
Flavin mononucleotideA form of vitamin B2 used to restore riboflavin in anemia, migraine, alcoholism, and hyperhomocysteinemia.
2-IminobiotinNot Available
3-Hydroxybutyryl-Coenzyme ANot Available
Succinyl-Coenzyme ANot Available
Dihydrolipoic AcidNot Available
DethiobiotinNot Available
Coenzyme F420Not Available
Coenzyme A persulfideCoenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
(R)-methylmalonyl-CoANot Available
LumichromeNot Available
L-erythro-7,8-dihydrobiopterin7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
7,8-DihydroneopterinNot Available
Malonyl-CoAA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
LumiflavinNot Available
5-methyltetrahydrofolic acid5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine...
Sitimagene ceradenovecIntended for the treatment of brain cancer.
RanpirnaseFor the treatment of various forms of cancer.
MitoquinoneInvestigated for use/treatment in hepatitis (viral, C) and parkinson's disease.
PEG-uricaseInvestigated for use/treatment in hyperuricemia.
Nelipepimut-SInvestigated for use/treatment in prostate cancer and breast cancer.
ButyrylcholinesteraseNot Available
DiaPep 277Investigated for use/treatment in diabetes mellitus type 1, autoimmune diseases, and diabetes mellitus type 2.
MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
Ubiquinone Q1Not Available
Ubiquinone Q2Not Available
AfliberceptA vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy, and metastatic colorectal cancer
Asparaginase Erwinia chrysanthemiAn asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma.
IdebenoneAn analogue of ubiquinone used for the treatment of visual impairment in adolescent and adult patients with Leber’s Hereditary Optic Neuropathy (LHON).
UbidecarenoneA cofactor found in various dietary supplements.
Levomefolic acidA folate supplement used to prevent neural tube defects in pregnancy or folate deficiency.
UbiquinolUbiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human...
LevoleucovorinA folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer.
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
Recombinant Cholera Toxin B SubunitRecombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
VatiquinoneVatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.
LuspaterceptAn erythroid maturation agent used to treat anemia secondary to beta thalassemia, myelodysplastic syndromes, and neoplasms.
AntroquinonolAntroquinonol has been used in trials studying the treatment of Hyperlipidemias, Non-small Cell Lung Cancer, and Non-small Cell Lung Cancer Stage IV.
RonopterinRonopterin has been used in trials studying the treatment of Traumatic Brain Injury.
LometrexolLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
CMX-2043CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
Olipudase alfaA recombinant human acid sphingomyelinase used to treat Acid Sphingomyelinase Deficiency (ASMD) in children and adults.
Glucose oxidaseGlucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.
Factor XIII (human)A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency.
Coagulation factor X humanA coagulation factor used to treat Factor X deficiency to control bleeding.
Trenonacog alfaHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
LysozymeAn enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
ElapegademaseA recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency.
Riboflavin tetrabutyrateNot Annotated
Calaspargase pegolAn asparagine specific enzyme used to treat acute lymphoblastic leukemia.
Pegvorhyaluronidase alfaPegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
DalanterceptDalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma).
NeopterinNeopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).
Marzeptacog alfa (activated)Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia).
Vocimagene amiretrorepvecVocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca...
Valanafusp alfaValanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS I).
Coagulation factor XIaCoagulation factor XIa is under investigation in clinical trial NCT01701947 (HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency).
ReloxaliaseReloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria).
Alunacedase alfaAlunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
ThioctamideAn ingredient in nutritional products for liver health.
VEGFR2-169VEGFR2-169 is under investigation in clinical trial NCT00655785 (Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)).
Pegylated Recombinant Human Arginase IPegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
RibaxamaseRibaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Deoxyribonuclease IDeoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of...
Pegunigalsidase alfaA recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease.
Avalglucosidase alfaA lysosomal glycogen-specific enzyme that is used to treat patients one year of age and older with late-onset Pompe disease, or lysosomal acid alpha-glucosidase (GAA) deficiency.
Botulinum toxin type FNot Annotated
Glyceraldehyde-3-Phosphate DehydrogenaseNot Annotated
FolitixorinNot Annotated
CBP-501Not Annotated
SOT-107Investigated for use/treatment in brain cancer.
TERT-572Not Available
Saposin CSaposin C is a lysosomal protein. Recombinant, non-glycosylated Saposin C is an active ingredient of BXQ-350, which is a novel, investigational anti-neoplastic therapy. BXQ-350 consists of Saposin C and the...
AnacaulaseA mix of proteolytic enzymes indicated for eschar removal in adults with deep partial thickness and/or full-thickness thermal burns.
Red blood cell-encapsulated L-asparaginaseRed blood cell-encapsulated L-asparaginase is Asparaginase Escherichia coli encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. It is being investigated in...
Atidarsagene autotemcelA gene therapy comprising autologous CD34+ enriched stem cells encoding the human arylsulfatase A (ARSA) gene used to treat metachromatic leukodystrophy (MLD).
PegzilarginasePegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Cipaglucosidase alfaA recombinant human acid alpha-glucosidase used to treat late-onset Pompe disease in adults.
Tralesinidase alfaTralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type...
Apadamtase alfaA recombinant human ADAMTS13 for enzyme replacement therapy in patients with congenital thrombotic thrombocytopenic purpura.
DimericineNot Annotated
BAX 335BAX 335 is an adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of hemophilia B.
XMMME-001-RTANot Annotated
XomaZyme-791Not Annotated
AnanainNot Annotated
ComosainNot Annotated
EP-217609Not Annotated
CalmangafodipirNot Annotated
PF-05230907PF-05230907 is a recombinant activated Factor X variant.
Liprotamase lipaseNot Annotated
Cytochrome CCytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain.
Microbial collagenaseNot Annotated
Drugs & Drug Targets
DrugTargetType
Dornase alfaDNAtarget
AlteplaseFibrinogen alpha chaintarget
AlteplasePlasminogentarget
AlteplasePlasminogen activator inhibitor 1target
AlteplaseFibrinogen gamma chaintarget
UrokinaseUrokinase plasminogen activator surface receptortarget
UrokinasePlasminogentarget
UrokinasePlasminogen activator inhibitor 2target
UrokinasePlasminogen activator inhibitor 1target
UrokinasePlasma serine protease inhibitortarget
UrokinaseNidogen-1target
UrokinaseLow-density lipoprotein receptor-related protein 2target
UrokinaseSuppressor of tumorigenicity 14 proteintarget
UrokinaseMacrophage metalloelastaseenzyme
ReteplaseFibrinogen alpha chaintarget
ReteplasePlasminogentarget
ReteplasePlasminogen activator inhibitor 1target
AnistreplaseFibrinogen alpha chaintarget
AnistreplasePlasminogentarget
AnistreplasePlasminogen activator inhibitor 1target
TenecteplaseUrokinase plasminogen activator surface receptortarget
TenecteplasePlasminogen activator inhibitor 1target
TenecteplaseFibrinogen alpha chaintarget
TenecteplasePlasminogen activator inhibitor 2target
TenecteplaseTetranectintarget
TenecteplaseKeratin, type II cytoskeletal 8target
TenecteplaseAnnexin A2target
TenecteplaseCalreticulintarget
TenecteplaseCalnexintarget
TenecteplaseProlow-density lipoprotein receptor-related protein 1target
TenecteplasePlasminogentarget
Coagulation factor VIIa Recombinant HumanCoagulation factor Xtarget
Coagulation factor VIIa Recombinant HumanTissue factortarget
Coagulation factor VIIa Recombinant HumanTissue factor pathway inhibitortarget
Coagulation factor VIIa Recombinant HumanVitamin K-dependent gamma-carboxylasetarget
Coagulation factor VIIa Recombinant HumanCoagulation factor VIItarget
Botulinum toxin type BVesicle-associated membrane protein 1target
Botulinum toxin type BVesicle-associated membrane protein 2target
Botulinum toxin type BSynaptotagmin-2target
Collagenase clostridium histolyticumCollagen alpha-1(I) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(II) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(III) chaintarget
RasburicaseUric acidtarget
ImigluceraseGlucocerebrosidetarget
Drotrecogin alfaCoagulation factor VIIItarget
Drotrecogin alfaCoagulation factor Vtarget
Drotrecogin alfaPlasminogen activator inhibitor 1target
Drotrecogin alfaThrombomodulintarget
Drotrecogin alfaVitamin K-dependent protein Starget
Drotrecogin alfaProthrombintarget
Drotrecogin alfaPlatelet factor 4target
Drotrecogin alfaPlasma serine protease inhibitortarget
Drotrecogin alfaSerpin B6target
Drotrecogin alfaEndothelial protein C receptortarget
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
StreptokinasePlasminogentarget
StreptokinaseProteinase-activated receptor 1target
StreptokinaseCytosolic phospholipase A2enzyme
AlgluceraseGlucocerebrosidetarget
Agalsidase betaGlobotriaosylceramidetarget
Agalsidase betaCation-dependent mannose-6-phosphate receptortransporter
Pyridoxal phosphateCystathionine beta-synthasetarget
Pyridoxal phosphateAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
Pyridoxal phosphateGlutamate decarboxylase 1target
Pyridoxal phosphateKynureninasetarget
Pyridoxal phosphateSerine hydroxymethyltransferase, cytosolictarget
Pyridoxal phosphateCysteine desulfurase, mitochondrialtarget
Pyridoxal phosphateAspartate aminotransferase, cytoplasmictarget
Pyridoxal phosphateOrnithine aminotransferase, mitochondrialtarget
Pyridoxal phosphateOrnithine decarboxylasetarget
Pyridoxal phosphateKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
Pyridoxal phosphate4-aminobutyrate aminotransferase, mitochondrialtarget
Pyridoxal phosphatePyridoxine-5'-phosphate oxidasetarget
Pyridoxal phosphateSphingosine-1-phosphate lyase 1target
Pyridoxal phosphateTyrosine aminotransferasetarget
Pyridoxal phosphateKynurenine--oxoglutarate transaminase 1target
Pyridoxal phosphateGlycogen phosphorylase, liver formtarget
Pyridoxal phosphateSerine palmitoyltransferase 2target
Pyridoxal phosphateCysteine sulfinic acid decarboxylasetarget
Pyridoxal phosphateHistidine decarboxylasetarget
Pyridoxal phosphateArginine decarboxylasetarget
Pyridoxal phosphateL-serine dehydratase/L-threonine deaminasetarget
Pyridoxal phosphate2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialtarget
Pyridoxal phosphateGlycine dehydrogenase [decarboxylating], mitochondrialtarget
Pyridoxal phosphateAlanine aminotransferase 1target
Pyridoxal phosphatePhosphoserine aminotransferasetarget
Pyridoxal phosphate5-aminolevulinate synthase, nonspecific, mitochondrialtarget
Pyridoxal phosphateSerine--pyruvate aminotransferasetarget
Pyridoxal phosphatePyridoxal phosphate phosphatasetarget
Pyridoxal phosphateSerine palmitoyltransferase 1target
Pyridoxal phosphateCystathionine gamma-lyasetarget
Pyridoxal phosphateBranched-chain-amino-acid aminotransferase, cytosolictarget
Pyridoxal phosphateBranched-chain-amino-acid aminotransferase, mitochondrialtarget
Pyridoxal phosphateProline synthase co-transcribed bacterial homolog proteintarget
Pyridoxal phosphateAspartate aminotransferase, mitochondrialtarget
Pyridoxal phosphateGlycogen phosphorylase, brain formtarget
Pyridoxal phosphateGlycogen phosphorylase, muscle formtarget
Pyridoxal phosphateAromatic-L-amino-acid decarboxylasetarget
Pyridoxal phosphateSerine hydroxymethyltransferasetarget
Pyridoxal phosphateSelenocysteine lyase varianttarget
Pyridoxal phosphatePhosphorylasetarget
Pyridoxal phosphate5-aminolevulinate synthasetarget
Pyridoxal phosphateGlutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)target
Pyridoxal phosphateDDC proteintarget
Pyridoxal phosphateKynurenine--oxoglutarate transaminase 3target
Pyridoxal phosphateGlutamate decarboxylase-like protein 1target
Pyridoxal phosphateSelenocysteine lyasetarget
Pyridoxal phosphateImmunoglobulin superfamily member 10target
Pyridoxal phosphate5-phosphohydroxy-L-lysine phospho-lyasetarget
Pyridoxal phosphateGlutamate decarboxylase 1 (Brain, 67kDa)target
Pyridoxal phosphateSerine hydroxymethyltransferase, mitochondrialtarget
Pyridoxal phosphate5-aminolevulinate synthase, erythroid-specific, mitochondrialtarget
Pyridoxal phosphateAlanine aminotransferase 2target
Pyridoxal phosphateMolybdenum cofactor sulfurasetarget
Pyridoxal phosphateSerine dehydratase-liketarget
Pyridoxal phosphateHepatic peroxysomal alanine:glyoxylate aminotransferasetarget
Pyridoxal phosphateSerine racemasetarget
Pyridoxal phosphateO-phosphoseryl-tRNA(Sec) selenium transferasetarget
Pyridoxal phosphateSerine palmitoyltransferase 3target
Pyridoxal phosphateGlutamic acid decarboxylasetarget
Pyridoxal phosphateAlanine-glyoxylate aminotransferase homologtarget
Pyridoxal phosphateAspartate aminotransferasetarget
Tetrahydrofolic acidC-1-tetrahydrofolate synthase, cytoplasmictarget
Tetrahydrofolic acidBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialtarget
Tetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
Tetrahydrofolic acidCytosolic 10-formyltetrahydrofolate dehydrogenasetarget
Tetrahydrofolic acidMethionine synthasetarget
Tetrahydrofolic acidFormimidoyltransferase-cyclodeaminasetarget
Tetrahydrofolic acidBifunctional purine biosynthesis protein PURHtarget
Tetrahydrofolic acidSerine hydroxymethyltransferase, cytosolictarget
Tetrahydrofolic acidSerine hydroxymethyltransferase, mitochondrialtarget
Tetrahydrofolic acidMethylenetetrahydrofolate reductasetarget
Tetrahydrofolic acidSerine hydroxymethyltransferasetarget
Tetrahydrofolic acidMethionyl-tRNA formyltransferase, mitochondrialtarget
Tetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
BiotinPropionyl-CoA carboxylase beta chain, mitochondrialtarget
BiotinBiotin--protein ligasetarget
BiotinMethylcrotonoyl-CoA carboxylase beta chain, mitochondrialtarget
BiotinAcetyl-CoA carboxylase 2target
BiotinMethylcrotonoyl-CoA carboxylase subunit alpha, mitochondrialtarget
BiotinPyruvate carboxylase, mitochondrialtarget
BiotinPropionyl-CoA carboxylase alpha chain, mitochondrialtarget
BiotinAcetyl-CoA carboxylase 1target
BiotinCytochrome P450 1B1enzyme
BiotinSodium-dependent multivitamin transportertransporter
BiotinSodium-coupled monocarboxylate transporter 1transporter
NADHUDP-glucose 6-dehydrogenasetarget
NADHAlcohol dehydrogenase 1Atarget
NADHSorbitol dehydrogenasetarget
NADHAlcohol dehydrogenase 4target
NADHAlcohol dehydrogenase 1Ctarget
NADHAlcohol dehydrogenase 1Btarget
NADHAlcohol dehydrogenase class 4 mu/sigma chaintarget
NADHGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmictarget
NADHL-lactate dehydrogenase A-like 6Atarget
NADHAlcohol dehydrogenase class-3target
NADHAldose reductasetarget
NADH3-hydroxyacyl-CoA dehydrogenase type-2target
NADHMalate dehydrogenase, mitochondrialtarget
NADHL-lactate dehydrogenase A chaintarget
NADHNAD-dependent malic enzyme, mitochondrialtarget
NADHPeroxisomal multifunctional enzyme type 2target
NADHL-lactate dehydrogenase A-like 6Btarget
NADHL-lactate dehydrogenase C chaintarget
NADHL-lactate dehydrogenase B chaintarget
NADHPeroxisomal bifunctional enzymetarget
NADHHydroxyacyl-coenzyme A dehydrogenase, mitochondrialtarget
NADHNADP-dependent malic enzyme, mitochondrialtarget
NADHD-beta-hydroxybutyrate dehydrogenase, mitochondrialtarget
NADHMalate dehydrogenase, cytoplasmictarget
NADH3-hydroxyisobutyrate dehydrogenase, mitochondrialtarget
NADHTestosterone 17-beta-dehydrogenase 3target
NADH3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
NADHNADP-dependent malic enzymetarget
NADHD-3-phosphoglycerate dehydrogenasetarget
NADH3-keto-steroid reductasetarget
NADHIsocitrate dehydrogenase [NAD] subunit gamma, mitochondrialtarget
NADHIsocitrate dehydrogenase [NAD] subunit beta, mitochondrialtarget
NADHIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
NADHEstradiol 17-beta-dehydrogenase 1target
NADHEstradiol 17-beta-dehydrogenase 2target
NADH11-cis retinol dehydrogenasetarget
NADHGDH/6PGL endoplasmic bifunctional proteintarget
NADHEstradiol 17-beta-dehydrogenase 8target
NADHAldo-keto reductase family 1 member C4target
NADHInosine-5'-monophosphate dehydrogenase 2target
NADHAldo-keto reductase family 1 member C3target
NADH15-hydroxyprostaglandin dehydrogenase [NAD(+)]target
NADHGDP-L-fucose synthasetarget
NADHAldo-keto reductase family 1 member C1target
NADHCorticosteroid 11-beta-dehydrogenase isozyme 1target
NADH3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
NADH3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
NADHInosine-5'-monophosphate dehydrogenase 1target
NADHTrifunctional enzyme subunit alpha, mitochondrialtarget
NADHAldehyde dehydrogenase, mitochondrialtarget
NADHCorticosteroid 11-beta-dehydrogenase isozyme 2target
NADHAldo-keto reductase family 1 member C2target
NADHSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingtarget
NADHAldehyde dehydrogenase family 3 member B2target
NADHMethylmalonate-semialdehyde dehydrogenase [acylating], mitochondrialtarget
NADHAldehyde dehydrogenase, dimeric NADP-preferringtarget
NADHRetinal dehydrogenase 1target
NADHGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
NADH4-trimethylaminobutyraldehyde dehydrogenasetarget
NADHAldehyde dehydrogenase family 1 member A3target
NADHAldehyde dehydrogenase X, mitochondrialtarget
NADHAldehyde dehydrogenase family 3 member B1target
NADHGlyceraldehyde-3-phosphate dehydrogenasetarget
NADHRetinal dehydrogenase 2target
NADHFatty aldehyde dehydrogenasetarget
NADHSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
NADHAlpha-aminoadipic semialdehyde dehydrogenasetarget
NADHFlavin reductase (NADPH)target
NADHPyrroline-5-carboxylate reductase 2target
NADHPyrroline-5-carboxylate reductase 1, mitochondrialtarget
NADHGlutamate dehydrogenase 1, mitochondrialtarget
NADHPyruvate dehydrogenase E1 component subunit beta, mitochondrialtarget
NADHPyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrialtarget
NADHPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialtarget
NADHBiliverdin reductase Atarget
NADHShort-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
NADHDihydrofolate reductasetarget
NADH2-oxoglutarate dehydrogenase, mitochondrialtarget
NADHGlutamate dehydrogenase 2, mitochondrialtarget
NADH7-dehydrocholesterol reductasetarget
NADHRibosyldihydronicotinamide dehydrogenase [quinone]target
NADHNADH-ubiquinone oxidoreductase chain 2target
NADHAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
NADHNADH-ubiquinone oxidoreductase chain 3target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialtarget
NADHC-1-tetrahydrofolate synthase, cytoplasmictarget
NADHBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialtarget
NADHDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialtarget
NADHNADH-cytochrome b5 reductase 3target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11target
NADHNADH-ubiquinone oxidoreductase chain 4target
NADHDihydropteridine reductasetarget
NADHNADH-ubiquinone oxidoreductase chain 1target
NADHNAD(P) transhydrogenase, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialtarget
NADHNADH-ubiquinone oxidoreductase chain 4Ltarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1target
NADHNADH-ubiquinone oxidoreductase chain 6target
NADHNADH-ubiquinone oxidoreductase chain 5target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6target
NADHAcyl carrier protein, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8target
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 subunit C2target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1target
NADHNADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7target
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6target
NADHNADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialtarget
NADHDihydrolipoyl dehydrogenase, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialtarget
NADHGlutathione reductase, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 5target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13target
NADHCysteine dioxygenase type 1target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrialtarget
NADHNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2target
NADHNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialtarget
NADHCytochrome P450 4A11target
NADHDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
NADHAminomethyltransferase, mitochondrialtarget
NADHMethylsterol monooxygenase 1target
NADHHeme oxygenase 1target
NADHHeme oxygenase 2target
NADHSteroid 17-alpha-hydroxylase/17,20 lyasetarget
NADHTyrosinasetarget
NADHXanthine dehydrogenase/oxidaseenzyme
NADHAldehyde oxidaseenzyme
NADHAlcohol dehydrogenase 6enzyme
NADHAlcohol dehydrogenase [NADP(+)]enzyme
NADHAlcohol dehydrogenase 1Aenzyme
NADHAlcohol dehydrogenase 1Benzyme
NADHAlcohol dehydrogenase 4enzyme
NADHAlcohol dehydrogenase class-3enzyme
NADHAlcohol dehydrogenase class 4 mu/sigma chainenzyme
LeucovorinSolute carrier family 22 member 8transporter
IdursulfasePerilipin-3target
IdursulfaseDermatan sulfatetarget
IdursulfaseHeparan sulfatetarget
Alglucosidase alfaCation-dependent mannose-6-phosphate receptortarget
Alglucosidase alfaGlycogentarget
GalsulfasePerilipin-3target
GalsulfaseDermatan sulfatetarget
Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
Flavin adenine dinucleotideNitric oxide synthase, braintarget
Flavin adenine dinucleotideNAD(P)H dehydrogenase [quinone] 1target
Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideERO1-like protein betatarget
Flavin adenine dinucleotideGlutathione reductase, mitochondrialtarget
Flavin adenine dinucleotideNADPH-ferredoxin reductase FprAtarget
Flavin adenine dinucleotideNADH-cytochrome b5 reductase 3target
Flavin adenine dinucleotideCholesterol oxidasetarget
Flavin adenine dinucleotideThymidylate synthase ThyXtarget
Flavin adenine dinucleotidePyruvate oxidasetarget
Flavin adenine dinucleotideGlutathione reductasetarget
Flavin adenine dinucleotideMonomeric sarcosine oxidasetarget
Flavin adenine dinucleotideTrypanothione reductasetarget
Flavin adenine dinucleotideRibosyldihydronicotinamide dehydrogenase [quinone]target
Flavin adenine dinucleotideIsovaleryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideXanthine dehydrogenase/oxidasetarget
Flavin adenine dinucleotideCholesterol oxidasetarget
Flavin adenine dinucleotideDihydropyrimidine dehydrogenase [NADP(+)]target
Flavin adenine dinucleotideD-lactate dehydrogenasetarget
Flavin adenine dinucleotideThioredoxin reductase 1, cytoplasmictarget
Flavin adenine dinucleotideIsobutyryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideApoptosis-inducing factor 1, mitochondrialtarget
Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
Flavin adenine dinucleotideFlavohemoproteintarget
Flavin adenine dinucleotideGlycine oxidasetarget
Flavin adenine dinucleotideNADPH--cytochrome P450 reductasetarget
Flavin adenine dinucleotideGlutaryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideMedium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideD-amino-acid oxidasetarget
Flavin adenine dinucleotideBifunctional protein PutAtarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Atarget
Flavin adenine dinucleotideShort-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideL-amino-acid oxidasetarget
Flavin adenine dinucleotide2,4-dienoyl-CoA reductase [NADPH]target
Flavin adenine dinucleotide2-oxopropyl-CoM reductase, carboxylatingtarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideThioredoxin reductasetarget
Flavin adenine dinucleotide5,10-methylenetetrahydrofolate reductasetarget
Flavin adenine dinucleotideN,N-dimethylglycine oxidasetarget
Flavin adenine dinucleotideNADH peroxidasetarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideSulfite reductase [NADPH] flavoprotein alpha-componenttarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideAcyl-CoA dehydrogenase, short-chain specifictarget
Flavin adenine dinucleotideFerredoxin reductasetarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideAmine oxidase, flavin-containing proteintarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideL-aspartate oxidasetarget
Flavin adenine dinucleotideCryptochrome DASHtarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideNADH-cytochrome b5 reductase 1target
Flavin adenine dinucleotideOxidoreductasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Btarget
Flavin adenine dinucleotideNADPH:adrenodoxin oxidoreductase, mitochondrialtarget
Flavin adenine dinucleotidePeroxisomal acyl-coenzyme A oxidase 1target
Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
Flavin adenine dinucleotideFAD-linked sulfhydryl oxidase ALRtarget
Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
Flavin adenine dinucleotideFlavohemoproteintarget
Flavin adenine dinucleotidePhenol 2-hydroxylase component Btarget
Flavin adenine dinucleotideMethylenetetrahydrofolate reductasetarget
Flavin adenine dinucleotidePutidaredoxin reductasetarget
Flavin adenine dinucleotideNAD(P)H dehydrogenase (quinone)target
Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
Flavin adenine dinucleotide4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerasetarget
Flavin adenine dinucleotide4-cresol dehydrogenase [hydroxylating] flavoprotein subunittarget
Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
Flavin adenine dinucleotideOuter membrane protein p64k or PM-6target
Flavin adenine dinucleotideGlutathione reductasetarget
Flavin adenine dinucleotidePhenylacetone monooxygenasetarget
Flavin adenine dinucleotideBenzoate 1,2-dioxygenase electron transfer componenttarget
Flavin adenine dinucleotidePutative acyl-CoA dehydrogenasetarget
Flavin adenine dinucleotideFkbItarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideMersacidin decarboxylasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Benzyme
Flavin adenine dinucleotideNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialtarget
3-Acetylpyridine Adenine Dinucleotide4-hydroxy-tetrahydrodipicolinate reductasetarget
AlfimepraseFibrinogen alpha chaintarget
AlfimepraseFibrinogen beta chaintarget
DesmoteplasePlasminogentarget
AncrodFibrinogen alpha chaintarget
FibrinolysinPlasminogen activator inhibitor 1target
FibrinolysinUrokinase-type plasminogen activatortarget
LanoteplaseUrokinase plasminogen activator surface receptortarget
LanoteplaseFibrinogen alpha chaintarget
LanoteplaseKallikrein-1target
LanoteplaseLaminin subunit alpha-5target
LanoteplaseCoagulation factor Xtarget
LanoteplaseFibronectintarget
LanoteplasePlasminogen activator inhibitor 2target
LanoteplaseTetranectintarget
LanoteplaseKeratin, type II cytoskeletal 8target
LanoteplaseAnnexin A2target
LanoteplaseLaminin subunit beta-1target
LanoteplaseLaminin subunit gamma-1target
LanoteplaseLaminin subunit alpha-1target
LanoteplaseCalreticulintarget
LanoteplaseCalnexintarget
LanoteplaseProlow-density lipoprotein receptor-related protein 1target
LanoteplaseLaminin subunit alpha-3target
ChymopapainBone marrow proteoglycantarget
Taliglucerase alfaGlucocerebrosidetarget
OcriplasminAlpha-2-macroglobulintarget
OcriplasminAlpha-2-antiplasmintarget
OcriplasminFibronectintarget
Asfotase alfaPyrophosphatetarget
PegloticaseUric acidtarget
PapainToll-like receptor 4target
ThrombinProteinase-activated receptor 1target
ThrombinProteinase-activated receptor 4target
ThrombinCoagulation factor XItarget
ThrombinCoagulation factor XIII A chaintarget
ThrombinCoagulation factor XIII B chaintarget
ThrombinFibrinogen alpha chaintarget
ThrombinFibrinogen beta chaintarget
ThrombinFibrinogen gamma chaintarget
ThrombinCoagulation factor Vtarget
ThrombinCoagulation factor VIIItarget
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
TilactaseLactosetarget
Ferric pyrophosphate citrateFerritin light chaintarget
Ferric pyrophosphate citrateFerritin heavy chaintarget
Ferric pyrophosphate citrateHemoglobin subunit alphatarget
Ferric pyrophosphate citrateHemoglobin subunit betatarget
Andexanet alfaTissue factor pathway inhibitortarget
CocarboxylaseAcetolactate synthase, catabolictarget
CocarboxylasePyruvate dehydrogenase E1 componenttarget
CocarboxylasePyruvate-flavodoxin oxidoreductasetarget
CocarboxylaseIndole-3-pyruvate decarboxylasetarget
CocarboxylaseCarboxyethylarginine synthasetarget
CocarboxylaseTransketolase 1target
CocarboxylaseRNAtarget
CocarboxylaseBenzoylformate decarboxylaseenzyme
CocarboxylasePyruvate oxidaseenzyme
HyaluronidaseHyaluronic acidtarget
HyaluronidaseTransforming growth factor beta-1target
Thrombin alfaCoagulation factor VIIItarget
Thrombin alfaCoagulation factor Vtarget
Thrombin alfaFibrinogen alpha chaintarget
Thrombin alfaFibrinogen beta chaintarget
Thrombin alfaFibrinogen gamma chaintarget
Coagulation factor VII humanTissue factortarget
Coagulation factor VII humanCoagulation factor Xtarget
Coagulation factor VII humanCoagulation factor IXtarget
Cerliponase alfaCation-independent mannose-6-phosphate receptortarget
Pancrelipase lipaseDietary fattarget
Hyaluronidase (human recombinant)Hyaluronic acidtarget
Hyaluronidase (human recombinant)Transforming growth factor beta-1target
Agalsidase alfaCation-dependent mannose-6-phosphate receptortransporter
Agalsidase alfaGlobotriaosylceramidetarget
Coagulation Factor IX HumanCoagulation factor Xtarget
Coagulation Factor IX HumanCoagulation factor XItarget
Coagulation Factor IX HumanCoagulation factor VIItarget
Coagulation Factor IX HumanCoagulation factor VIIItarget
Coagulation Factor IX HumanProthrombintarget
Coagulation Factor IX HumanProlow-density lipoprotein receptor-related protein 1target
Coagulation Factor IX HumanVitamin K-dependent gamma-carboxylasetarget
Botulinum toxin type ASynaptosomal-associated protein 25target
Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
Botulinum toxin type ASerum albumincarrier
Hyaluronidase (ovine)Transforming growth factor beta-1target
Hyaluronidase (ovine)Serum albumincarrier
Hyaluronidase (ovine)Hyaluronantarget
LaronidaseIduronic acidtarget
Velaglucerase alfaGlucosylceramidasetarget
Alpha-1-proteinase inhibitorNeutrophil elastasetarget
Dipyrromethane CofactorPorphobilinogen deaminasetarget
PlasminogenTissue-type plasminogen activatorenzyme
PlasminogenUrokinase-type plasminogen activatorenzyme
Pancrelipase proteaseDietary proteintarget
Pyrroloquinoline QuinoneQuinohemoprotein ethanol dehydrogenase type-1target
Pyrroloquinoline QuinoneQuinoprotein glucose dehydrogenase Btarget
Pyrroloquinoline QuinonePyrroloquinoline-quinone synthasetarget
Pyrroloquinoline QuinoneQuinoprotein ethanol dehydrogenasetarget
Pyrroloquinoline QuinoneQuinohemoprotein alcohol dehydrogenase ADH IIBtarget
Pancrelipase amylaseDietary starchtarget
Lipoic acidLipoyltransferase 1, mitochondrialtarget
Lipoic acidSodium-dependent multivitamin transportertarget
Lipoic acidLipoyl synthase, mitochondrialtarget
Lipoic acidNADPH--cytochrome P450 reductaseenzyme
Coenzyme AGalactoside O-acetyltransferasetarget
Coenzyme A3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Coenzyme AFatty acid metabolism regulator proteintarget
Coenzyme AHistone acetyltransferase KAT5target
Coenzyme A2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferasetarget
Coenzyme AAcetyl-CoA acetyltransferase, cytosolictarget
Coenzyme AAcetyl-CoA acetyltransferasetarget
Coenzyme AStreptogramin A acetyltransferasetarget
Coenzyme ACitrate synthase, mitochondrialtarget
Coenzyme A3-oxoacyl-[acyl-carrier-protein] synthase 3target
Coenzyme AFormyl-coenzyme A transferasetarget
Coenzyme ADihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complextarget
Coenzyme APantothenate kinasetarget
Coenzyme AAcetyl-coenzyme A synthetasetarget
Coenzyme AAcyl-CoA-binding proteintarget
Coenzyme AFormyl-coenzyme A transferasetarget
Coenzyme ACarnitine O-acetyltransferasetarget
Coenzyme ACrotonobetainyl-CoA:carnitine CoA-transferasetarget
Coenzyme AFormate acetyltransferase 1target
Coenzyme AMalate synthase Gtarget
Coenzyme A3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Coenzyme APhosphopantetheine adenylyltransferasetarget
Coenzyme AHolo-[acyl-carrier-protein] synthasetarget
Coenzyme AProtease synthase and sporulation negative regulatory protein PAI 1target
Coenzyme AGentamicin 3'-acetyltransferasetarget
Coenzyme ABifunctional protein GlmUtarget
Coenzyme AAcetyl transferasetarget
Coenzyme AUncharacterized N-acetyltransferase YvbKtarget
Coenzyme AAminoglycoside N(6')-acetyltransferase type 1target
Coenzyme AAcyl-CoA hydrolasetarget
Coenzyme AUncharacterized acyl-CoA thioester hydrolase HI_0827target
Coenzyme A3-oxoacyl-[acyl-carrier-protein] synthase 3target
Coenzyme AMycothiol acetyltransferasetarget
Coenzyme AHistone acetyltransferase KAT2Atarget
Coenzyme AAcyl-CoA hydrolasetarget
Coenzyme AHistone acetyltransferase KAT2Btarget
Coenzyme A1,4-Dihydroxy-2-naphthoyl-CoA synthasetarget
Coenzyme ACitrate synthasetarget
Coenzyme AAminoglycoside 2'-N-acetyltransferasetarget
Coenzyme AAac(6')-Ii proteintarget
Coenzyme A4'-phosphopantetheinyl transferase sfptarget
Coenzyme AUncharacterized proteintarget
Coenzyme ASerine acetyltransferasetarget
Coenzyme ACitrate synthasetarget
Coenzyme A4-hydroxybenzoyl-CoA thioesterasetarget
Coenzyme AAminoglycoside 2'-N-acetyltransferaseenzyme
NADPHThioredoxin reductase 1, cytoplasmictarget
NADPHGlucose-6-phosphate 1-dehydrogenasetarget
NADPHPteridine reductase 1target
NADPHGlucose--fructose oxidoreductasetarget
NADPHDihydropyrimidine dehydrogenase [NADP(+)]target
NADPHAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
Nicotinamide adenine dinucleotide phosphateIsocitrate dehydrogenase [NADP]target
Nicotinamide adenine dinucleotide phosphateAldose reductasetarget
Nicotinamide adenine dinucleotide phosphateGlucose-6-phosphate 1-dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateAldo-keto reductase family 1 member C2target
Nicotinamide adenine dinucleotide phosphateEstradiol 17-beta-dehydrogenase 1target
Nicotinamide adenine dinucleotide phosphateNAD(P) transhydrogenase, mitochondrialtarget
Nicotinamide adenine dinucleotide phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1target
Nicotinamide adenine dinucleotide phosphateSepiapterin reductasetarget
Nicotinamide adenine dinucleotide phosphatePteridine reductase 1target
Nicotinamide adenine dinucleotide phosphateL-xylulose reductasetarget
Nicotinamide adenine dinucleotide phosphateIsocitrate dehydrogenase [NADP] cytoplasmictarget
Nicotinamide adenine dinucleotide phosphateAldo-keto reductase family 1 member C1target
Nicotinamide adenine dinucleotide phosphateNitric oxide synthase, braintarget
Nicotinamide adenine dinucleotide phosphateGlucose-6-phosphate 1-dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateDihydrofolate reductasetarget
Nicotinamide adenine dinucleotide phosphateADP-L-glycero-D-manno-heptose-6-epimerasetarget
Nicotinamide adenine dinucleotide phosphateC-1-tetrahydrofolate synthase, cytoplasmictarget
Nicotinamide adenine dinucleotide phosphateAldo-keto reductase family 1 member C3target
Nicotinamide adenine dinucleotide phosphateFlavin reductase (NADPH)target
Nicotinamide adenine dinucleotide phosphateIsocitrate dehydrogenase [NADP]target
Nicotinamide adenine dinucleotide phosphateDihydrofolate reductasetarget
Nicotinamide adenine dinucleotide phosphateQuinone oxidoreductasetarget
Nicotinamide adenine dinucleotide phosphate3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Nicotinamide adenine dinucleotide phosphateAlcohol dehydrogenase 1Btarget
Nicotinamide adenine dinucleotide phosphateNADPH--cytochrome P450 reductasetarget
Nicotinamide adenine dinucleotide phosphateShikimate dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateNADP-dependent isopropanol dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateGDP-L-fucose synthasetarget
Nicotinamide adenine dinucleotide phosphateAspartate-semialdehyde dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphate2,4-dienoyl-CoA reductase [NADPH]target
Nicotinamide adenine dinucleotide phosphateNADP-dependent malic enzymetarget
Nicotinamide adenine dinucleotide phosphateDihydrofolate reductasetarget
Nicotinamide adenine dinucleotide phosphateNAD(P) transhydrogenase subunit betatarget
Nicotinamide adenine dinucleotide phosphate3-oxoacyl-[acyl-carrier-protein] reductase FabGtarget
Nicotinamide adenine dinucleotide phosphateDehydrogenase/reductase SDR family member 11target
Nicotinamide adenine dinucleotide phosphateMalate dehydrogenase, cytoplasmictarget
Nicotinamide adenine dinucleotide phosphateOxidoreductase YdhFtarget
Nicotinamide adenine dinucleotide phosphatePutative pteridine reductase 2target
Nicotinamide adenine dinucleotide phosphateEstradiol 17-beta-dehydrogenase 8target
Nicotinamide adenine dinucleotide phosphateAlcohol dehydrogenase [NADP(+)]target
Nicotinamide adenine dinucleotide phosphatePutative ketoacyl reductasetarget
Nicotinamide adenine dinucleotide phosphate2,4-dienoyl-CoA reductase, mitochondrialtarget
Nicotinamide adenine dinucleotide phosphateOxidoreductase, short chain dehydrogenase/reductase familytarget
Nicotinamide adenine dinucleotide phosphateProstaglandin F synthasetarget
Nicotinamide adenine dinucleotide phosphateGeneral stress protein 69target
Nicotinamide adenine dinucleotide phosphateFerredoxin--NADP reductasetarget
Nicotinamide adenine dinucleotide phosphateBifunctional protein MdtAtarget
Nicotinamide adenine dinucleotide phosphateAlcohol dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateNADPH:adrenodoxin oxidoreductase, mitochondrialtarget
Nicotinamide adenine dinucleotide phosphateFerredoxin--NADP reductasetarget
Nicotinamide adenine dinucleotide phosphate2,5-diketo-D-gluconic acid reductase Atarget
Nicotinamide adenine dinucleotide phosphateProtein IolStarget
Nicotinamide adenine dinucleotide phosphateNADP-dependent glyceraldehyde-3-phosphate dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphateProstaglandin reductase 1target
Nicotinamide adenine dinucleotide phosphateSulfite reductase [NADPH] flavoprotein alpha-componenttarget
Nicotinamide adenine dinucleotide phosphateAldo-keto reductase family 1 member B10target
Nicotinamide adenine dinucleotide phosphateAlcohol dehydrogenase (NADP(+))target
Nicotinamide adenine dinucleotide phosphateNADP-dependent fatty aldehyde dehydrogenasetarget
Nicotinamide adenine dinucleotide phosphatePutative dehydrogenase/reductase SDR family member 4-like 2target
Nicotinamide adenine dinucleotide phosphateAldehyde reductasetarget
BiopterinSepiapterin reductasetarget
Biopterin6-pyruvoyl tetrahydrobiopterin synthasetarget
BiopterinDihydrofolate reductasetarget
ProthrombinFibrinogen alpha chaintarget
ProthrombinFibrinogen beta chaintarget
ProthrombinCoagulation factor XIII A chaintarget
ProthrombinCarboxypeptidase B2target
ProthrombinCoagulation factor Xenzyme
Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
Denileukin diftitoxCytokine receptor common subunit gammatarget
Denileukin diftitoxInterleukin-2 receptor subunit betatarget
Asparaginase Escherichia coliL-asparaginetarget
Asparaginase Escherichia coliThyroxine-binding globulincarrier
PegaspargaseL-asparaginetarget
PegaspargaseThyroxine-binding globulincarrier
PegademaseAdenosinetarget
PegademaseGrowth factor receptor-bound protein 2target
RiboflavinFlavin reductase (NADPH)target
RiboflavinRiboflavin kinasetarget
RiboflavinRiboflavin synthasetarget
RiboflavinAmine oxidase [flavin-containing] Aenzyme
RiboflavinMethylenetetrahydrofolate reductaseenzyme
RiboflavinSolute carrier family 22 member 6transporter
SapropterinPhenylalanine-4-hydroxylasetarget
SapropterinNitric oxide synthase, endothelialtarget
SapropterinTyrosine 3-monooxygenasetarget
SapropterinTryptophan 5-hydroxylase 1target
SapropterinProstaglandin G/H synthase 2enzyme
SapropterinP-glycoprotein 1transporter
4-hydroxybenzoyl-CoA4-chlorobenzoyl CoA dehalogenasetarget
4-hydroxybenzoyl-CoA4-hydroxybenzoyl-CoA thioesterasetarget
Methacrylyl-Coenzyme AIsobutyryl-CoA dehydrogenase, mitochondrialtarget
Desulfo-coenzyme AChloramphenicol acetyltransferasetarget
Molybdenum cofactorAldehyde oxidoreductasetarget
Myristoyl-CoaGlycylpeptide N-tetradecanoyltransferasetarget
Myristoyl-CoaGlycylpeptide N-tetradecanoyltransferase 2target
Pyridoxine phosphatePyridoxine 5'-phosphate synthasetarget
Pyridoxine phosphateOrnithine decarboxylasetarget
Pyridoxine phosphatePyridoxine-5'-phosphate oxidaseenzyme
Pyridoxine phosphatePyridoxine 5'-phosphate phosphataseenzyme
Hexanoyl-CoAEnoyl-CoA hydratase, mitochondrialtarget
Octanoyl-Coenzyme AEnoyl-CoA hydratase, mitochondrialtarget
Octanoyl-Coenzyme AEnoyl-CoA delta isomerase 1, mitochondrialtarget
Octanoyl-Coenzyme AMedium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Propanoyl-CoAPropionyl-CoA carboxylase complex B subunittarget
Acetoacetyl-CoAHydroxyacyl-coenzyme A dehydrogenase, mitochondrialtarget
Acetoacetyl-CoAAcetyl-CoA acetyltransferasetarget
Acetoacetyl-CoAShort-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Acetoacetyl-CoAEnoyl-CoA hydratase, mitochondrialtarget
Acetoacetyl-CoA1,4-Dihydroxy-2-naphthoyl-CoA synthasetarget
Acetoacetyl-CoAAcyl-CoA dehydrogenase, short-chain specifictarget
Acetoacetyl-CoAHMG-CoA synthasetarget
Acetoacetyl-CoA3-hydroxy-3-methylglutaryl CoA synthasetarget
Flavin mononucleotideFlavin reductase (NADPH)target
Flavin mononucleotideHydroxyacid oxidase 1target
Flavin mononucleotidePyridoxine-5'-phosphate oxidasetarget
Flavin mononucleotideMajor NAD(P)H-flavin oxidoreductasetarget
Flavin mononucleotideRiboflavin kinasetarget
Flavin mononucleotideOxygen-insensitive NADPH nitroreductasetarget
Flavin mononucleotideNitric oxide synthase, braintarget
Flavin mononucleotideDihydroorotate dehydrogenase (quinone)target
Flavin mononucleotideDihydropyrimidine dehydrogenase [NADP(+)]target
Flavin mononucleotideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideOxygen-insensitive NAD(P)H nitroreductasetarget
Flavin mononucleotideChorismate synthasetarget
Flavin mononucleotide2,4-dienoyl-CoA reductase [NADPH]target
Flavin mononucleotideDihydroorotate dehydrogenase A (fumarate)target
Flavin mononucleotidePyridoxine/pyridoxamine 5'-phosphate oxidasetarget
Flavin mononucleotidePentaerythritol tetranitrate reductasetarget
Flavin mononucleotideFMN-dependent NADH-azoreductasetarget
Flavin mononucleotideEpidermin decarboxylasetarget
Flavin mononucleotideFMN-dependent NADH-azoreductasetarget
Flavin mononucleotideChorismate synthasetarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotidePutative uncharacterized proteintarget
Flavin mononucleotidePutative monooxygenase MoxCtarget
Flavin mononucleotidetRNA-dihydrouridine synthasetarget
Flavin mononucleotideProtein NrdItarget
Flavin mononucleotideProbable aromatic acid decarboxylasetarget
Flavin mononucleotide(S)-mandelate dehydrogenasetarget
Flavin mononucleotideFMN-dependent NADPH-azoreductasetarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideSerine/threonine-protein kinase Sgk1target
Flavin mononucleotideOxygen-insensitive NAD(P)H nitroreductasetarget
Flavin mononucleotideNitric oxide reductasetarget
Flavin mononucleotideIsopentenyl-diphosphate delta-isomerasetarget
Flavin mononucleotideTrimethylamine dehydrogenasetarget
Flavin mononucleotideRubredoxin-oxygen oxidoreductasetarget
Flavin mononucleotideRiboflavin biosynthesis protein RibFtarget
Flavin mononucleotideMorphinone reductasetarget
Flavin mononucleotideNADPH-flavin oxidoreductasetarget
Flavin mononucleotideRibosomal protein S6 kinase alpha-4target
Flavin mononucleotidePhenazine biosynthesis protein PhzGtarget
Flavin mononucleotideHydroxyacid oxidase 2target
Flavin mononucleotideNAD(P)H dehydrogenase (quinone)target
Flavin mononucleotideFlavodoxin-1target
Flavin mononucleotideIsopentenyl-diphosphate delta-isomerasetarget
Flavin mononucleotideNADH dehydrogenasetarget
Flavin mononucleotideFMN-binding proteintarget
Flavin mononucleotideNitroreductase family proteintarget
Flavin mononucleotideNADPH--cytochrome P450 reductasetarget
Flavin mononucleotidePhosphopantothenoylcysteine decarboxylasetarget
Flavin mononucleotidePhzGtarget
Flavin mononucleotideFerredoxin-dependent glutamate synthase 2target
Flavin mononucleotideNADPH--cytochrome P450 reductaseenzyme
2-IminobiotinStreptavidintarget
3-Hydroxybutyryl-Coenzyme AHydroxyacyl-coenzyme A dehydrogenase, mitochondrialtarget
Succinyl-Coenzyme A2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferasetarget
Dihydrolipoic AcidAminomethyltransferasetarget
Dihydrolipoic AcidGlycine cleavage system H protein, mitochondrialtarget
Dihydrolipoic AcidDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
Dihydrolipoic Acid[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
DethiobiotinATP-dependent dethiobiotin synthetase BioD 1target
DethiobiotinBiotin synthasetarget
DethiobiotinATP-dependent dethiobiotin synthetase BioDtarget
Coenzyme A persulfideIsovaleryl-CoA dehydrogenase, mitochondrialtarget
(R)-methylmalonyl-CoAMethylmalonyl-CoA carboxyltransferase 12S subunittarget
LumichromeFlavin reductase (NADPH)target
LumichromeRiboflavin biosynthesis protein RibFtarget
L-erythro-7,8-dihydrobiopterinPhenylalanine-4-hydroxylasetarget
L-erythro-7,8-dihydrobiopterinPteridine reductase 1target
L-erythro-7,8-dihydrobiopterinNitric oxide synthase, inducibletarget
L-erythro-7,8-dihydrobiopterinTyrosine 3-monooxygenasetarget
L-erythro-7,8-dihydrobiopterinPterin-4-alpha-carbinolamine dehydratasetarget
L-erythro-7,8-dihydrobiopterinDihydroneopterin aldolasetarget
7,8-DihydroneopterinDihydroneopterin aldolasetarget
Malonyl-CoA3-oxoacyl-[acyl-carrier-protein] synthase 3target
5-methyltetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
5-methyltetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
RanpirnaseDNAtarget
PEG-uricaseUric acid degradation bifunctional proteintarget
Nelipepimut-SHLA class I histocompatibility antigen, A-2 alpha chaintarget
Nelipepimut-SHLA class I histocompatibility antigen, A-3 alpha chaintarget
MangafodipirAlpha-2-macroglobulincarrier
MangafodipirSerum albumincarrier
MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
MangafodipirNatural resistance-associated macrophage protein 2transporter
Ubiquinone Q1Photosynthetic reaction center cytochrome c subunittarget
Ubiquinone Q1Reaction center protein H chaintarget
Ubiquinone Q1Reaction center protein L chaintarget
Ubiquinone Q1Reaction center protein M chaintarget
Ubiquinone Q1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
Ubiquinone Q1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrialtarget
Ubiquinone Q1Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialtarget
Ubiquinone Q1Succinate dehydrogenase cytochrome b560 subunit, mitochondrialtarget
Ubiquinone Q1Thiol:disulfide interchange protein DsbAtarget
Ubiquinone Q1Disulfide bond formation protein Btarget
Ubiquinone Q1NrfC proteintarget
Ubiquinone Q1Thiosulfate reductasetarget
Ubiquinone Q1Hypothetical membrane spanning proteintarget
Ubiquinone Q2Succinate dehydrogenase flavoprotein subunittarget
Ubiquinone Q2Succinate dehydrogenase iron-sulfur subunittarget
Ubiquinone Q2Succinate dehydrogenase cytochrome b556 subunittarget
Ubiquinone Q2Succinate dehydrogenase hydrophobic membrane anchor subunittarget
Ubiquinone Q2Cytochrome c1, heme protein, mitochondrialtarget
Ubiquinone Q2Cytochrome btarget
Ubiquinone Q2Cytochrome b-c1 complex subunit 1, mitochondrialtarget
Ubiquinone Q2Cytochrome b-c1 complex subunit 2, mitochondrialtarget
Ubiquinone Q2Cytochrome b-c1 complex subunit 6, mitochondrialtarget
Ubiquinone Q2Cytochrome b-c1 complex subunit 8target
Ubiquinone Q2Cytochrome b-c1 complex subunit Rieske, mitochondrialtarget
Ubiquinone Q2Cytochrome b-c1 complex subunit 10target
Ubiquinone Q2Cytochrome b-c1 complex subunit 7target
Ubiquinone Q2Cytochrome b-c1 complex subunit 9target
Ubiquinone Q2Photosynthetic reaction center cytochrome c subunittarget
Ubiquinone Q2Reaction center protein H chaintarget
Ubiquinone Q2Reaction center protein L chaintarget
Ubiquinone Q2Reaction center protein M chaintarget
Ubiquinone Q2Disulfide bond formation protein Btarget
Ubiquinone Q2Cytochrome btarget
Ubiquinone Q2Ubiquinol-cytochrome c reductase iron-sulfur subunittarget
Ubiquinone Q2Cytochrome c1target
Ubiquinone Q2Reaction center protein L chaintarget
Ubiquinone Q2Reaction center protein M chaintarget
Ubiquinone Q2Reaction center protein H chaintarget
AfliberceptVascular endothelial growth factor Atarget
AfliberceptPlacenta growth factortarget
AfliberceptVascular endothelial growth factor Btarget
UbidecarenoneNADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialtarget
UbidecarenoneSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
UbidecarenoneLow-density lipoprotein receptorcarrier
UbidecarenoneVery low-density lipoprotein receptorcarrier
UbidecarenoneP-glycoprotein 1transporter
Ubidecarenone3-hydroxy-3-methylglutaryl-coenzyme A reductaseenzyme
Levomefolic acidProton-coupled folate transportertransporter
Levomefolic acidFolate transporter 1transporter
Levomefolic acidMethionine synthaseenzyme
LevoleucovorinSerine hydroxymethyltransferasetarget
LometrexolDihydrofolate reductasetarget
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget
ElapegademaseAdenosinetarget
Calaspargase pegolL-asparaginetarget
Pegunigalsidase alfaGlobotriaosylceramidetarget
Avalglucosidase alfaCation-independent mannose-6-phosphate receptortarget
SOT-107Glioma pathogenesis-related protein 1target
AnacaulaseCytochrome P450 2C8enzyme
AnacaulaseCytochrome P450 2C9enzyme
AnacaulaseAlpha-1-antichymotrypsintarget
AnacaulaseAlpha-2-macroglobulintarget
Atidarsagene autotemcelHuman Arylsulfatase A mRNAtarget
Cipaglucosidase alfaCation-independent mannose-6-phosphate receptortarget
Cipaglucosidase alfaAlpha glucosidase (GAA)target
Apadamtase alfavon Willebrand factortarget