Peptides, Cyclic
- Name
- Peptides, Cyclic
- Accession Number
- DBCAT000099
- Description
Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).
- Drugs
Drug Drug Description Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Cyclosporine A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. Octreotide A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Romidepsin A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma. Viomycin Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. Thiostrepton Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally... Tyrothricin A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. Voclosporin A calcineurin inhibitor for the treatment of lupus nephritis (LN) in patients diagnosed with systemic lupus erythematosus (SLE). Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Eptifibatide A peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention. Dotatate gallium Ga-68 Dotatate gallium 68 is one of the most prominent radiopharmaceuticals used in imaging with positron emission tomography. It binds to the somatostatin-2 receptor which is usually overexpressed in many neuroendocrine... Echinomycin Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis. Dactinomycin An actinomycin used to treat a wide variety of cancers. Gramicidin D A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections. Anidulafungin An antifungal used in the treatment of several types of candida infections. Caspofungin An echinocandin used to treat a variety of fungal infections. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Quinupristin An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections. Virginiamycin M1 For the treatment of bacterial infections. Dalfopristin An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. Gallichrome Not Available Virginiamycin S1 One of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. It is used to treat infections... Ramoplanin For the treatment of bacterial infections. Plitidepsin Intended for the treatment of various forms of cancer. PM02734 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. Fusafungine Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections. Enviomycin Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. Emodepside Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the... Virginiamycin Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent... Valspodar Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. Alisporivir Alisporivir has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C. SCY-635 SCY-635 has been investigated for the treatment of Chronic Hepatitis C and Hepatitis C Infection. Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Dolastatin 10 Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others. 9-(N-methyl-L-isoleucine)-cyclosporin A 9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse. Pristinamycin Not Annotated Lutetium Lu 177 dotatate A radiolabeled somatostatin analog used to treat somatostatin receptor positive gastroenteropancreatic neuroendocrine tumors. Valinomycin A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately... Basifungin Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , . Copper oxodotreotide Cu-64 A Cu labeled somatostatin analog used in positron emission tomography to detect certain types of neuroendocrine tumors. Rezafungin An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis. Edotreotide yttrium Y-90 Not Annotated Lutetium Lu177 Edotreotide Not Annotated OBP-801 OBP-801 has been used in trials studying the treatment of Solid Tumor. 99mTc-HYNIC (Tyr3)-octreotide Not Annotated Edotreotide Not Annotated Rencofilstat Not Annotated - Drugs & Drug Targets