Anti-Retroviral Agents
- Name
- Anti-Retroviral Agents
- Accession Number
- DBCAT000123 (DBCAT003778)
- Description
Agents used to treat RETROVIRIDAE INFECTIONS.
- Drugs
Drug Drug Description Enfuvirtide An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. Nelfinavir A viral protease inhibitor used in the treatment of HIV infection. Indinavir A protease inhibitor used to treat HIV infection. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Tenofovir disoproxil A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Efavirenz A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Amprenavir A protease inhibitor used to treat HIV infection. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Didanosine A reverse transcriptase inhibitor used to treat HIV. Tipranavir A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. Zalcitabine A dideoxynucleoside used to treat HIV. Abacavir An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Lopinavir An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. Calanolide A For use in combination treatment of HIV infection (AIDS). Leronlimab A humanized monoclonal antibody being investigated Etravirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. Raltegravir An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Dolutegravir An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. Cenicriviroc Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex. Atevirdine Atevirdine has been used in trials studying the treatment of HIV Infections. Lobucavir Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Tenofovir A nucleotide analog indicated in the treatment of HIV infections. Emivirine Emivirine has been used in trials studying the treatment of HIV Infections. Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. UC-781 Investigated for use/treatment in HIV infection. R-82913 Not Available Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). Cabotegravir An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection. Pradefovir mesylate Investigated for use as a prodrug for Hepsera in treating hepatitis (viral, B). Pradefovir Pradefovir is a prodrug of adefovir. Elvitegravir An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. BMS-488043 Investigated for use/treatment in HIV infection. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Aplaviroc Investigated for use/treatment in HIV infection. Capravirine Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. Dapivirine Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures. Fostemsavir An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Ibalizumab A CD4-specific antibody used to treat HIV infections. PF-232798 PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects). Rovafovir etalafenamide Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen). Tenofovir exalidex Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers). Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Tipranavir C-14 Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects). BMS-955176 BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults). Viral Macrophage-Inflammatory Protein Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer... HIV Integrase Inhibitor HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects). Azodicarbonamide Not Annotated Carbovir Not Annotated - Drugs & Drug Targets