Insulin
- Name
- Insulin
- Accession Number
- DBCAT000170 (DBCAT000136)
- Description
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
- Drugs
Drug Drug Description Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. NN344 Investigated for use/treatment in diabetes mellitus type 1 and 2. Insulin peglispro Not Annotated Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Insulin beef Insulin beef has been discontinued in the US and Canada since 2017. Insulin tregopil code text here Insulin argine Not Annotated C-peptide C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy). Pegylated synthetic human c-peptide Not Annotated Insulin icodec Not Annotated Proinsulin human Not Annotated - Drugs & Drug Targets