Accession Number

Biological catalysts and their cofactors.

DrugDrug Description
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
Sebelipase alfaA recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency.
DesoxyribonucleaseDesoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into...
Alkaline PhosphataseInvestigated for use/treatment in ulcerative colitis.
Asfotase alfaAn enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP).
Dornase alfaA synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis.
IdursulfaseA purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients.
GalsulfaseA recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme.
RanpirnaseFor the treatment of various forms of cancer.
ALTU-135Investigated for use/treatment in cystic fibrosis and pancreatic disorders.
ButyrylcholinesteraseNot Available
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Olipudase alfaA recombinant human acid sphingomyelinase used to treat Acid Sphingomyelinase Deficiency (ASMD) in children and adults.
Pancrelipase lipaseA lipase used to treat pancreatic exocrine insufficiency.
Deoxyribonuclease IDeoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of...
CBP-501Not Annotated
DimericineNot Annotated
Liprotamase lipaseNot Annotated
Drugs & Drug Targets
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
Asfotase alfaPyrophosphatetarget
Dornase alfaDNAtarget
IdursulfaseDermatan sulfatetarget
IdursulfaseHeparan sulfatetarget
GalsulfaseDermatan sulfatetarget
Pancrelipase lipaseDietary fattarget