Esterases
- Name
- Esterases
- Accession Number
- DBCAT000190
- Description
Biological catalysts and their cofactors.
- Drugs
Drug Drug Description Pancrelipase A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. Sebelipase alfa A recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency. Desoxyribonuclease Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into... Alkaline Phosphatase Investigated for use/treatment in ulcerative colitis. Asfotase alfa An enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP). Dornase alfa A synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis. Idursulfase A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. Ranpirnase For the treatment of various forms of cancer. ALTU-135 Investigated for use/treatment in cystic fibrosis and pancreatic disorders. Butyrylcholinesterase Not Available Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. Olipudase alfa A recombinant human acid sphingomyelinase used to treat Acid Sphingomyelinase Deficiency (ASMD) in children and adults. Pancrelipase lipase A lipase used to treat pancreatic exocrine insufficiency. Deoxyribonuclease I Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of... CBP-501 Not Annotated Dimericine Not Annotated Liprotamase lipase Not Annotated - Drugs & Drug Targets
Drug Target Type Pancrelipase Dietary fat target Pancrelipase Dietary protein target Pancrelipase Dietary starch target Asfotase alfa Pyrophosphate target Dornase alfa DNA target Idursulfase Perilipin-3 target Idursulfase Dermatan sulfate target Idursulfase Heparan sulfate target Galsulfase Perilipin-3 target Galsulfase Dermatan sulfate target Ranpirnase DNA target Pancrelipase lipase Dietary fat target