Amino Acids, Cyclic
- Name
- Amino Acids, Cyclic
- Accession Number
- DBCAT000244
- Description
A class of amino acids characterized by a closed ring structure.
- Drugs
Drug Drug Description Histidine An amino acid commonly found as a component of total parenteral nutrition. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Technetium Tc-99m disofenin A radiopharmaceutical diagnostic agent used for hepatobiliary scans. Fluorodopa (18F) Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes... Solriamfetol Solriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744]. Melphalan flufenamide A melphalan prodrug used to treat relapsed or refractory multiple myeloma. Cycloleucine Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments. Phenylalanine An amino acid commonly found as a component of total parenteral nutrition. Tyrosine An amino acid commonly found as a component in total parenteral nutrition. Tryptophan An amino acid commonly found as a component of total parenteral nutrition. Proline An amino acid commonly found as a component of total parenteral nutrition. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Dextrothyroxine A thyroid hormone used to treat hyperlipidemia. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Metyrosine A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma. Tirofiban A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. Melphalan An alkylating agent used to treat multiple myeloma, ovarian carcinoma, uveal melanoma with unresectable hepatic metastases, and for high-dose conditioning before hematopoietic stem cell transplant in patients. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... Tetraiodothyroacetic acid Not Available Epicaptopril Not Available Pyrrole-2-Carboxylate Not Available N-(2-Acetamido)Iminodiacetic Acid Not Available Oxitriptan A naturally occurring amino acid that is used to manage post-hypoxic myoclonus. Pidolic acid There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in... N,O-didansyl-L-tyrosine Not Available Diphthamide Not Available 5-fluorotryptophan 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. N-Acetylproline Not Available L-tyrosinamide Not Available 3-Tyrosine Not Available Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. 4-Iodo-L-phenylalanine Not Available 3-nitro-L-tyrosine Not Available Batimastat Not Available 5-Oxoprolinal Not Available Phenylalanylamide Not Available 1-Methylhistidine Not Available L-proline betaine Not Available 6-hydroxydopa quinone Not Available Paratoulene phosphate Not Available Tryptophanamide Not Available Phenyldehydroalanine Not Available CDP323 Investigated for use/treatment in multiple sclerosis. Rupintrivir Investigated for use/treatment in viral infection. LX1031 Irritable bowel syndrome (IBS) and other gastrointestinal disorders WX-UK1 Investigated for use/treatment in solid tumors. AB192 Investigated for use/treatment in diabetes mellitus type 2. GW-559090 Investigated for use/treatment in asthma and allergic rhinitis. Etilevodopa Investigated for use/treatment in parkinson's disease. methyl L-phenylalaninate Not Available p-Benzoyl-L-phenylalanine Not Available Zofenoprilat Not Available Hydroxyproline Used in France as a combination product for the treatment of small, superficial wounds. Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Azelnidipine For the treatment of hypertension. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Paritaprevir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. N-acetyltyrosine An amino acid used in total parenteral nutrition. Pidotimod A synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections. Lifitegrast A medication used to treat dry eye disease. Vixotrigine Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. Danoprevir Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Vaniprevir Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C... Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Oxothiazolidinecarboxylic acid Procysteine has been used in trials studying the treatment of HIV Infections. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Indoximod Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others. Macimorelin A medication used to treat adult growth hormone deficiency. Tiropramide A medication indicated in the treatment of spastic pain of the gastrointestinal system. Zofenopril An ACE inhibitor indicated in the treatment of hypertension. Melevodopa A methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease. Oxaceprol Not Annotated Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Nordazepam A benzodiazepine indicated in the treatment of insomnia. Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. Narlaprevir Not Annotated GS-9191 GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts). Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Danicopan Danicopan is under investigation in clinical trial NCT03459443 (A Proof of Concept Study for a 12 Month Treatment in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN)). Efpeglenatide Efpeglenatide is under investigation in clinical trial NCT03713684 (Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in... MK-0668 Not Annotated TRC150094 TRC150094 is under investigation in clinical trial NCT03254446 (Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension). Carotegrast methyl Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and Efficacy of AJM300 in Participants With Active Ulcerative Colitis). Denagliptin Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM)). Fasoracetam Fasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations). Racemetyrosine Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer). Metadoxine A medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy. Nirmatrelvir An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19. Ergothioneine Not Annotated K-777 Not Annotated CPP-115 free base Not Annotated Nano-diamino-tetrac Not Annotated Nanvuranlat Not Annotated Chromium histidinate Not Annotated - Drugs & Drug Targets