Amino Acids, Neutral

Accession Number

DBCAT000246

Description

Amino acids with uncharged R groups or side chains.

Drugs

Drug	Drug Description
L-Glutamine	An amino acid commonly found as a component in total parenteral nutrition.
Serine	An amino acid commonly found as a component in total parenteral nutrition.
Cysteine	An amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose.
Acetylcysteine	A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
Carbocisteine	A expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
Methionine	An amino acid commonly found as a component in total parenteral nutrition.
Threonine	An amino acid commonly found as a component of total parenteral nutrition.
Asparagine	Used for nutritional supplementation, also for treating dietary shortage or imbalance.
D-Glutamine	A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of...
Cycloserine	A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
N-Acetylmethionine	An amino acid used as a peritoneal dialysis treatment in patients with renal failure and nutritional therapy in patients with nutritional deficiency or post-infection weakness.
S-Methylcysteine	Not Available
L-methionine (R)-S-oxide	Not Available
4-methylthio-2-oxobutanoic acid	Not Available
Cysteine-S-acetamide	Not Available
Isoglutamine	Not Available
L-serine O-sulfate	Not Available
S-Phosphocysteine	Not Available
L-methionine sulfone	Not Available
Trifluoromethionine	Not Available
Aceglutamide	Not Available
S-sulphocysteine	Not Available
Dexfosfoserine	An amino acid used for nutritional supplementation therapy in over-fatigue states.
beta-Hydroxyasparagine	Not Available
S-Benzylcysteine	Not Available
Droxidopa	A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
Delanzomib	Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin.
Bucillamine	Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
Ombrabulin	Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others.
Racemethionine	A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Desmeninol	An amino acid derivative indicated in the management of balanced protein metabolism in patients with renal dysfunction.
Phenylacetylglutamine	Not Annotated

Drugs & Drug Targets

Drug	Target	Type
L-Glutamine	CTP synthase 1	target
L-Glutamine	Amidophosphoribosyltransferase	target
L-Glutamine	Glutamine synthetase	target
L-Glutamine	Monocarboxylate transporter 10	transporter
L-Glutamine	Coagulation factor XIII A chain	enzyme
L-Glutamine	Glutaminase kidney isoform, mitochondrial	enzyme
L-Glutamine	Glutaminase liver isoform, mitochondrial	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 2	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 5	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 6	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase K	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 4	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase E	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase Z	enzyme
L-Glutamine	Sodium-coupled neutral amino acid transporter 3	transporter
L-Glutamine	Neutral amino acid transporter B(0)	transporter
L-Glutamine	GMP synthase [glutamine-hydrolyzing]	enzyme
L-Glutamine	Asparagine synthetase [glutamine-hydrolyzing]	enzyme
L-Glutamine	Kynurenine--oxoglutarate transaminase 1	enzyme
L-Glutamine	Phosphoribosylformylglycinamidine synthase	enzyme
L-Glutamine	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	enzyme
L-Glutamine	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2	enzyme
L-Glutamine	CAD protein	enzyme
L-Glutamine	Glutamine--tRNA ligase	enzyme
L-Glutamine	Glutamine-dependent NAD(+) synthetase	enzyme
L-Glutamine	Large neutral amino acids transporter small subunit 2	transporter
L-Glutamine	Sodium-coupled neutral amino acid transporter 1	transporter
L-Glutamine	Sodium-coupled neutral amino acid transporter 2	transporter
L-Glutamine	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	transporter
L-Glutamine	Y+L amino acid transporter 1	transporter
L-Glutamine	Y+L amino acid transporter 2	transporter
L-Glutamine	Large neutral amino acids transporter small subunit 1	transporter
L-Glutamine	B(0,+)-type amino acid transporter 1	transporter
Serine	Cystathionine beta-synthase	target
Serine	L-serine dehydratase/L-threonine deaminase	target
Serine	Serine racemase	target
Serine	Serine palmitoyltransferase 2	target
Serine	Serine palmitoyltransferase 1	target
Serine	Serine--tRNA ligase, cytoplasmic	target
Serine	Serine--pyruvate aminotransferase	target
Serine	Monocarboxylate transporter 10	transporter
Cysteine	Cysteine--tRNA ligase, cytoplasmic	target
Cysteine	Glutamate--cysteine ligase regulatory subunit	target
Cysteine	Glutamate--cysteine ligase catalytic subunit	target
Cysteine	Aspartate aminotransferase, cytoplasmic	target
Cysteine	Cystathionine gamma-lyase	target
Cysteine	Cystathionine beta-synthase	target
Cysteine	Cysteine dioxygenase type 1	target
Cysteine	Methylated-DNA--protein-cysteine methyltransferase	target
Cysteine	Glutathione synthetase	target
Cysteine	Probable cysteine--tRNA ligase, mitochondrial	target
Cysteine	Cysteine sulfinic acid decarboxylase	target
Cysteine	Cysteine desulfurase, mitochondrial	target
Cysteine	Monocarboxylate transporter 10	transporter
Cysteine	Aspartate aminotransferase, mitochondrial	target
Acetylcysteine	Solute carrier organic anion transporter family member 1B1	transporter
Acetylcysteine	NAPQI (N-acetyl-p-benzoquinone imine)	target
Acetylcysteine	Solute carrier family 22 member 6	transporter
Acetylcysteine	Aminoacylase-1	target
Acetylcysteine	Inhibitor of nuclear factor kappa-B kinase subunit alpha	target
Acetylcysteine	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Acetylcysteine	Glutathione synthetase	target
Acetylcysteine	Cystine/glutamate transporter	target
Acetylcysteine	Glutamate receptor ionotropic, NMDA 2B	target
Acetylcysteine	Glutamate receptor ionotropic, NMDA 1	target
Acetylcysteine	Glutamate receptor ionotropic, NMDA 2A	target
Acetylcysteine	Glutamate receptor ionotropic, NMDA 2D	target
Acetylcysteine	Glutamate receptor ionotropic, NMDA 3A	target
Acetylcysteine	Serum albumin	carrier
Acetylcysteine	Aminoacylase-1	enzyme
Carbocisteine	Cysteine dioxygenase type 1	enzyme
Carbocisteine	Phenylalanine-4-hydroxylase	enzyme
Carbocisteine	PI-PLC X domain-containing protein 3	target
Carbocisteine	Lactosylceramide alpha-2,3-sialyltransferase	enzyme
Carbocisteine	Lactosylceramide alpha-2,3-sialyltransferase	target
Methionine	Methionine synthase reductase	target
Methionine	Methionine synthase	target
Methionine	Methionine aminopeptidase 2	target
Methionine	Betaine--homocysteine S-methyltransferase 1	target
Methionine	S-methylmethionine--homocysteine S-methyltransferase BHMT2	target
Methionine	Glutamine synthetase	enzyme
Methionine	Methylenetetrahydrofolate reductase	enzyme
Methionine	Monocarboxylate transporter 10	transporter
Methionine	S-adenosylmethionine synthase isoform type-2	enzyme
Methionine	Methionine-R-sulfoxide reductase B2, mitochondrial	enzyme
Methionine	S-adenosylmethionine synthase isoform type-1	enzyme
Methionine	Methionine-R-sulfoxide reductase B1	enzyme
Methionine	Mitochondrial peptide methionine sulfoxide reductase	enzyme
Methionine	Methionine--tRNA ligase, cytoplasmic	enzyme
Methionine	Methionine--tRNA ligase, mitochondrial	enzyme
Methionine	Methionine adenosyltransferase 2 subunit beta	enzyme
Methionine	S-methylmethionine--homocysteine S-methyltransferase BHMT2	enzyme
Threonine	Threonine--tRNA ligase, cytoplasmic	target
Threonine	Threonine--tRNA ligase, mitochondrial	target
Threonine	Monocarboxylate transporter 10	transporter
Threonine	Beta-lactamase Toho-1	target
Asparagine	Neutral amino acid transporter B(0)	target
Asparagine	Asparagine synthetase [glutamine-hydrolyzing]	target
Asparagine	Asparagine--tRNA ligase, cytoplasmic	target
Asparagine	Isoaspartyl peptidase/L-asparaginase	target
Asparagine	Probable asparagine--tRNA ligase, mitochondrial	target
Asparagine	Monocarboxylate transporter 10	transporter
Asparagine	Sodium-coupled neutral amino acid transporters	target
D-Glutamine	Glutamate racemase	target
Cycloserine	D-alanine--D-alanine ligase A	target
Cycloserine	Alanine racemase	target
Cycloserine	Aromatic-L-amino-acid decarboxylase	enzyme
Cycloserine	Proton-coupled amino acid transporter 2	transporter
N-Acetylmethionine	N-acylamino acid racemase	target
N-Acetylmethionine	Rhodopsin	target
S-Methylcysteine	Cathepsin D	target
S-Methylcysteine	Fatty acid-binding protein, liver	carrier
S-Methylcysteine	Methylated-DNA--protein-cysteine methyltransferase	target
L-methionine (R)-S-oxide	Catalase	target
L-methionine (R)-S-oxide	Protease	target
L-methionine (R)-S-oxide	Amyloid beta A4 protein	target
4-methylthio-2-oxobutanoic acid	Aminotransferase	target
Cysteine-S-acetamide	Ribonuclease pancreatic	target
Cysteine-S-acetamide	2'-5'-oligoadenylate synthase 1	target
Isoglutamine	ATP synthase subunit b	target
S-Phosphocysteine	N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component	target
S-Phosphocysteine	Enamine/imine deaminase	target
L-methionine sulfone	Catalase	target
Trifluoromethionine	Methionine--tRNA ligase	target
Trifluoromethionine	Methionine aminopeptidase	target
Aceglutamide	N-acylamino acid racemase	target
Dexfosfoserine	3-phosphoinositide-dependent protein kinase 1	target
Dexfosfoserine	Serine/threonine-protein kinase pim-1	target
Dexfosfoserine	Protein kinase C theta type	target
Dexfosfoserine	Glycogen phosphorylase, liver form	target
Dexfosfoserine	Phosphomannomutase/phosphoglucomutase	target
Dexfosfoserine	Glycogen phosphorylase, muscle form	target
Dexfosfoserine	cAMP-dependent protein kinase catalytic subunit alpha	target
Dexfosfoserine	Anti-sigma F factor antagonist	target
Dexfosfoserine	Fimbrial protein	target
Dexfosfoserine	Alkaline phosphatase	target
Dexfosfoserine	Rhodopsin	target
Dexfosfoserine	Serpin B3	target
Dexfosfoserine	Endo-1,4-beta-xylanase Y	target
Dexfosfoserine	Serine/threonine-protein kinase TAO2	target
Dexfosfoserine	Potassium voltage-gated channel subfamily C member 4	target
Dexfosfoserine	Lithostathine-1-alpha	target
Dexfosfoserine	Mothers against decapentaplegic homolog 2	target
Dexfosfoserine	Glutaminase 1	target
Dexfosfoserine	Siroheme synthase	target
Dexfosfoserine	Phosphocarrier protein HPr	target
Dexfosfoserine	Cystic fibrosis transmembrane conductance regulator	target
beta-Hydroxyasparagine	Mannan-binding lectin serine protease 2	target
S-Benzylcysteine	Methylated-DNA--protein-cysteine methyltransferase	target
Droxidopa	Phenylalanine-4-hydroxylase	target
Droxidopa	Alpha-1A adrenergic receptor	target
Droxidopa	Alpha-1B adrenergic receptor	target
Droxidopa	Alpha-1D adrenergic receptor	target
Droxidopa	Alpha-2A adrenergic receptor	target
Droxidopa	Alpha-2B adrenergic receptor	target
Droxidopa	Alpha-2C adrenergic receptor	target
Droxidopa	Beta-1 adrenergic receptor	target
Droxidopa	Beta-2 adrenergic receptor	target
Droxidopa	Beta-3 adrenergic receptor	target
Droxidopa	Aromatic-L-amino-acid decarboxylase	enzyme
Droxidopa	Monocarboxylate transporter 10	transporter
Droxidopa	Sodium-dependent noradrenaline transporter	transporter