Amino Acids, Branched-Chain
- Name
- Amino Acids, Branched-Chain
- Accession Number
- DBCAT000344
- Description
Amino acids which have a branched carbon chain.
- Drugs
Drug Drug Description Leucine An amino acid commonly found as a component of total parenteral nutrition. Valine An amino acid commonly found as a component of total parenteral nutrition. Isoleucine An amino acid commonly found as a component of total parenteral nutrition. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. L-alloisoleucine Not Available 2-aminoisobutyric acid Not Available Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Promazine A phenothiazine used to manage schizophrenia. Leucine Phosphonic Acid Not Available Beta-Hydroxyleucine Not Available Ubenimex An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia. Norvaline A drug used to treat vaginal inflammation with betamethasone and tyrothricin. Rupintrivir Investigated for use/treatment in viral infection. PPI-2458 Investigated for use/treatment in lymphoma (non-hodgkin's) and solid tumors. Daclatasvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Sacubitril A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Valbenazine A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia and chorea associated with Huntington's disease. Vaniprevir Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C... Nirogacestat A gamma-secretase inhibitor used to treat desmoid tumors ORE-1001 ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor. Decernotinib Decernotinib has been used in trials studying the treatment of Drug Interactions and Rheumatoid Arthritis. Acetylleucine Used for treating vestibular-related imbalance and vertigo. Narlaprevir Not Annotated BMS-817399 BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis). Ravidasvir Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection). GC-376 free acid GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound... PF-07304814 PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the... Nirmatrelvir An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19. L-Acetylleucine Not Annotated GC-373 GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that... Aloxistatin Not Annotated - Drugs & Drug Targets