Pyrimidines
- Name
- Pyrimidines
- Accession Number
- DBCAT000349
- Description
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
- Drugs
Drug Drug Description Thiamine A vitamin used to correct vitamin B1 deficiency. Pyrimethamine An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. Butabarbital A barbiturate drug used as a sedative and hypnotic. Butalbital A barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine. Talbutal For use as a sedative and hypnotic. Trifluridine A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers. Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. Gemcitabine A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. Buspirone An anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression. Risperidone A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. Primidone An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. Methylphenobarbital For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Pemirolast A medication used to treat allergies such as hay fever and allergic conjunctivitis. Dipyridamole A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events. Cytarabine A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Phenobarbital A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. Dasatinib A tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia. Decitabine A chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression. Paliperidone An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders. Oxypurinol Intended for the treatment of congestive heart failure and hyperuricemia. Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Hexetidine An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa. Epirizole Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain. Trapidil Used in the treatment of chronic stable angina . Relugolix An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer. Brincidofovir An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease. Febarbamate Not Annotated Vibegron A beta-3 adrenergic agonist the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults. Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Tipiracil A thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies. N4-Hydroxycytidine A cytidine analog being investigated to treat COVID-19. Minoxidil An antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. Metharbital Metharbital is used for the treatment of epilepsy. Imatinib A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. Amobarbital A barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures. Aprobarbital Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment... Butobarbital For the treatment of insomnia. Heptabarbital Used mainly for sedation and hypnosis. Immucillin-G Not Available Freselestat Investigated for use/treatment in chronic obstructive pulmonary disease (COPD). Forodesine Investigated for use/treatment in lymphoma (non-hodgkin's) and leukemia (lymphoid). Ocaperidone Investigated for use/treatment in schizophrenia and schizoaffective disorders. Darapladib Investigated for use/treatment in atherosclerosis. Trametinib A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer. Pyrantel An anthelmintic used to treat helminth infections. Nicarbazin Not Annotated AZD-4877 AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others. Daprodustat A small-molecule hypoxia-inducible factor prolyl hydroxylase inhibitor used for the treatment of anemia in patients with chronic kidney disease. PF-06282999 Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects). Adavosertib MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others. Mirodenafil Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction. Gisadenafil Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia. PF-04447943 PF-04447943 has been investigated for the treatment of Alzheimer's Disease. Letaxaban Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome. TAK-733 TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies. Ulodesine Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease. Verdiperstat Verdiperstat has been used in trials studying the basic science and treatment of Multiple System Atrophy (MSA). Zoliflodacin Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea. Enibomal Not Annotated Proxibarbal Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing... Rimazolium Rimazolium is an experimental analgesic drug . Allobarbital Not Annotated Cyclobarbital Not Annotated Vinylbital Not Annotated IQP-0528 IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study). AZD-6482 AZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482). PRI-724 PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis). Cambinol An investigational histone deacetylase inhibitor that may have future use in cancer treatment. Nifekalant Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection). Ensifentrine Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD). Firsocostat Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)). Revaprazan Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)). Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Pentobarbital A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. Floxuridine An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy. Cidofovir An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. Secobarbital A barbiturate used for the short-term treatment of insomnia. Methohexital An anesthetic used to induce deep sedation. Chlordiazepoxide A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Fluorouracil A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. Propylthiouracil A thiourea antithyroid agent used to treat hyperthyroidism. Pentostatin An adenosine deaminase inhibitor used to treat hairy cell leukemia. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Uracil mustard Used for its antineoplastic properties. Azacitidine A pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome. Zalcitabine A dideoxynucleoside used to treat HIV. Flucytosine An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. Thiamylal Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. Telbivudine A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). Hexobarbital For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... Barbital A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... 5-fluorouridine 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine... Thymidine monophosphate 5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. Dihydrouracil Not Available Uridine diphosphate glucose A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and... Cytidine 3'-monophosphate Not Available Cocarboxylase The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. 5-methylcytidine 5'-monophosphate Not Available Cytidine A drug used to manage neuropsychiatric deficits associated with cerebrovascular diseases in combination with uridine. Orotic acid A drug used to manage uncomplicated liver dysfunction in combination with xanthine. Formycin Not Available Thymidine 5'-triphosphate Not Available 3'-Uridinemonophosphate Not Available Uridine A drug used to manage neuropsychiatric deficits associated with cerebrovascular diseases in combination with cytidine. Stavudine triphosphate Not Available Orotidylic acid Not Available UDP-alpha-D-glucuronic acid A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides.... Zebularine A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also... 2'-Deoxycytidine 5'-triphosphate Not Available Brivudine A drug used to treat herpes zoster. Deoxycytidylyl-3',5'-guanosine Not Available Cytidine-5'-Monophosphate A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase. Uracil An antineoplastic agent used in combination with tegafur to treat various cancers, including breast, prostate, and liver cancer. Thymine Not Available Galactose-uridine-5'-diphosphate A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides,... Eniluracil For the treatment of cancer in combination with 5-fluorouracil. 5-Iodouracil Not Available Zidovudine monophosphate Not Available Uridine monophosphate 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. 6-aza uridine 5'-monophosphate Not Available 2'-Deoxy-thymidine-beta-L-rhamnose Not Available 5-fluoro-2'-deoxyuridine-5'-monophosphate Not Available 2'-cytidylic acid Not Available 5-Aminouracil Not Available Deoxyuridine monophosphate Not Available 5,6-Diaminouracil Not Available Uridine 5'-triphosphate Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. 3-Methylcytosine Not Available Willardiine Willardiine is a compound isolated from seeds of Acacia willariana. Bropirimine Not Available Formycin B Not Available Sparsomycin An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem] TMP Not Available 1-Methylcytosine Not Available 3-Deazacytidine Not Available Thymidine Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in... Zidovudine diphosphate Not Available Cyclouridine Not Available Metoprine Not Available Cyclic 3',5'-thymidine monophosphate Not Available Troxacitabine Investigated for use/treatment in leukemia (myeloid). Denufosol For use as an inhaled treatment for cystic fibrosis. Thymectacin Investigated for use/treatment in colorectal cancer. Elacytarabine Investigated for use/treatment in leukemia (unspecified) and melanoma. Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Sapacitabine Investigated for use/treatment in solid tumors, cutaneous t-cell lymphoma, myelodysplastic syndrome, and leukemia (lymphoid). Tezacitabine Investigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer. Ropidoxuridine Investigated for use/treatment in cancer/tumors (unspecified). TAS-106 Investigated for use/treatment in solid tumors and cancer/tumors (unspecified). Clevudine Investigated for use/treatment in hepatitis (viral, B). 5-Benzylacyclouridine Not Available Emivirine Emivirine has been used in trials studying the treatment of HIV Infections. Sofosbuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. TAS-102 TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. It is composed of the thymidine phosphorylase... Fursultiamine Compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative. Barbexaclone Created for the treatment for epilepsy, with the intent of creating an antiepileptic with less sedative properties than phenobarbital. Carmofur Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy. Uridine triacetate A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Tegafur An antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers. Radgocitabine 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer. Benfotiamine A derivative of thiamine thought to be useful in the management of diabetic neuropathy, although evidence is lacking. Guadecitabine Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer. Sorivudine Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. Broxuridine Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer. Mericitabine Mericitabine has been investigated for the treatment of Hepatitis C, Chronic. Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of... Censavudine Censavudine has been used in trials studying the treatment of HIV-1 Infection. CE-224535 CE-224535 has been used in trials studying the treatment of Osteoarthritis. Citicoline An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Fozivudine Tidoxil Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Tetrahydrouridine Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others. Gemcitabine elaidate Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. Netivudine Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. Ritanserin Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders. Racivir Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has... Apricitabine Apricitabine has been used in trials studying the treatment of HIV Infections. Fiacitabine Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. LY-2334737 LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor. Resmetirom MGL-3196 has been used in trials studying the treatment of Non-alcoholic steatohepatitis and Heterozygous Familial Hypercholesterolemia. Doxifluridine Doxifluridine has been investigated for the treatment of Stomach Cancer. 5-fluoro-2'-deoxycytidine 5-fluoro-2'-deoxycytidine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, and Urinary Bladder Neoplasms, among others. 2'-fluoro-5-ethylarabinosyluracil 2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma,... Tunicamycin Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes... Sulbutiamine A thiamine derivative indicated in the treatment of asthenia. Edoxudine A deoxythymidine analog used to treat herpetic keratitis. Methylthiouracil Not Annotated Oxantel An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections. Ibacitabine Not Annotated Magnesium orotate Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat... Brodimoprim Not Annotated Benzylthiouracil Not Annotated Valopicitabine The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite... 2'-C-methylcytidine A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks... Lumicitabine Lumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to... Adafosbuvir Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335). Mavacamten A myosin inhibitor used to treat obstructive hypertrophic cardiomyopathy. osgemcitabine palabenamide NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study). ABT-072 ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat... Uprifosbuvir Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and... Trelagliptin A dipeptidyl peptidase-4 inhibitor indicated in the control of diabetes mellitus. Fialuridine Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU). Molnupiravir An orally bioavailable isopropylester cytidine analog used to treat COVID-19. Cedazuridine A cytidine deaminase inhibitor coadministered with the hypomethylating agent decitabine for the treatment of variable forms of myelodysplastic syndrome (MDS). Zinc orotate A zinc supplement indicated in zinc deficiency. Diquafosol A medication indicated to treat dry eyes associated with keratoconjunctival disorders. Thiamine disulfide A B-vitamin indicated to treat neurological conditions caused by B vitamin deficiency. Monophosphothiamine A B vitamin for supplementation to treat macrocytic anemia, and other conditions caused by B vitamin deficiencies. Fluorocyclopentenylcytosine Fluorocyclopentenylcytosine is under investigation in clinical trial NCT03189914 (RX-3117 in Combination With Abraxane® in Subjects With Metastatic Pancreatic Cancer). Miricorilant Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking... Azvudine Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)). Benzoyloxymethylthiamine Not Annotated Tolimidone Not Annotated MB07133 Not Annotated 5,6-dihydro-5-azacytidine Not Annotated Navuridine Not Annotated North-methanocarbathymidine Not Annotated Dihydrouridine Not Annotated ICG-001 Not Annotated - Drugs & Drug Targets