Cyclohexanes
- Name
- Cyclohexanes
- Accession Number
- DBCAT000358
- Description
Six-carbon alicyclic hydrocarbons.
- Drugs
Drug Drug Description Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. Tranexamic acid An antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders. Nitisinone A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods. Acitretin An oral retinoid used in the treatment of severe psoriasis. Picrotoxin Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates. Hexylcaine Used as a local anesthetic for surface application, infiltration or nerve block Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Adenosine A medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia. Tretinoin A vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications. Dicyclomine An antimuscarinic agent used to treat IBS. Isotretinoin A retinoid used to treat severe recalcitrant acne. Gabapentin An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. Cyclohexanol Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem] Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Ambroxol A medication indicated for airway secretion clearance therapy. Beta carotene A vitamin A precursor found in various nutritional supplements and health products. Bromhexine A mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance. Zeaxanthin Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some... Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Lutein Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance. Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Ciclopirox A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. Esketamine A NMDA receptor antagonist used for treatment-resistant depression. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Peridinin Not Available Prephenic acid Not Available TNP-470 O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms. Tiletamine This drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt... Crocin Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. Gacyclidine Gacyclidine has been used in trials studying the treatment of Tinnitus. Norbixin Norbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals). alpha-Carotene Not Annotated 1-Phenylcyclohexylamine Not Available Gabaculine Not Available Cyclohexanone Cyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an... 3-(cyclohexylamino)propanesulfonic acid Not Available Oseltamivir acid Not Available 4-Oxoretinol Not Available Isochorismic Acid Not Available Arotinoid acid Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. Anhydrovitamin A Not Available Violaxanthin Not Available Cilomilast Investigated for use/treatment in chronic obstructive pulmonary disease (COPD). Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. N-Ethylretinamide N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. Shikimate-3-Phosphate Not Available 3-Dehydroshikimate Not Available Voglibose An alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes. Apadenoson Investigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified). Fenretinide Investigated for use/treatment in macular degeneration. Atl146e Investigated for use/treatment in inflammatory disorders (unspecified). IRX-5183 Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified). LGD-1550 Investigated for use/treatment in cancer/tumors (unspecified). Astaxanthin Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid Not Available (4R)-limonene Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to... Lycopene An ingredient found in a variety of supplements and vitamins. Candoxatrilat A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,... Tanzisertib Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others. Lomibuvir Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection. Zuretinol acetate Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). MK-5108 MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors. AQX-1125 AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome. Motretinide Not Annotated Rociverine An antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms. 13-cis-12-(3'-Carboxyphenyl)retinoic acid Not Annotated Menthol Not Annotated Fucoxanthin Fucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). Fucoxanthin isis a marine carotenoid mainly found... Cryptoxanthin Not Annotated Menthone A medication used to treat stone formation in the gallbladder and liver. SP-420 SP-420 is under investigation in clinical trial NCT03801889 (SP-420 in Subjects With Transfusion-dependent Beta-thalassemia or Other Rare Anemias). Axomadol Axomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain). Peretinoin Not Annotated Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. Abscisic Acid Not Annotated Transcrocetinate Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes. Janagliflozin Janagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin). GS-100 GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence CC-90001 Not Annotated - Drugs & Drug Targets