Accession Number

Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)

DrugDrug Description
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
Tranexamic acidAn antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders.
AcitretinAn oral retinoid used in the treatment of severe psoriasis.
AdenosineA medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia.
DicyclomineAn antimuscarinic agent used to treat IBS.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
BromhexineA mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance.
FumagillinNot Available
PeridininNot Available
AdamantaneA tricyclo bridged hydrocarbon. [PubChem]
ArylacenamideInvestigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.
Bisphenol ZNot Available
Prephenic acidNot Available
CrocinCrocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
MK-0557MK0557 has been investigated for the treatment of Schizophrenia and Paranoid Schizophrenia.
GDC-0152GDC-0152 has been used in trials studying the treatment of Solid Cancers.
BeloranibBeloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
GacyclidineGacyclidine has been used in trials studying the treatment of Tinnitus.
NorbixinNorbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals).
alpha-CaroteneNot Annotated
LuteinXanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.
VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
HexylcaineUsed as a local anesthetic for surface application, infiltration or nerve block
RimantadineAn RNA synthesis inhibitor used to prevent influenza A infection.
AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
TretinoinA vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
SibutramineA norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
1-PhenylcyclohexylamineNot Available
RoflumilastA selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat plaque psoriasis.
GabaculineNot Available
CyclohexanoneCyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an...
AdamantanoneNot Available
3-(cyclohexylamino)propanesulfonic acidNot Available
Oseltamivir acidNot Available
4-OxoretinolNot Available
Isochorismic AcidNot Available
Arotinoid acidArotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
Anhydrovitamin ANot Available
ViolaxanthinNot Available
CyclohexanolMonohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem]
CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
N-EthylretinamideN-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Shikimate-3-PhosphateNot Available
3-DehydroshikimateNot Available
CycloleucineCycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
VogliboseAn alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
NeramexaneInvestigated for use/treatment in alzheimer's disease, hearing loss, and pain (acute or chronic).
ApadenosonInvestigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified).
FenretinideInvestigated for use/treatment in macular degeneration.
SQ-109Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis.
Atl146eInvestigated for use/treatment in inflammatory disorders (unspecified).
Paclitaxel docosahexaenoic acidInvestigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer.
IRX-5183Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified).
LGD-1550Investigated for use/treatment in cancer/tumors (unspecified).
AI-850Investigated for use/treatment in breast cancer and solid tumors.
Paclitaxel trevatideInvestigated for use/treatment in brain cancer.
TedisamilInvestigated for use/treatment in arrhythmia, atrial fibrillation, and angina.
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
AR-9281Investigated for use/treatment in hypertension.
AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
CabazitaxelAn antineoplastic agent used in combination with corticosteroids to treat metastatic castration-resistant prostate cancer in patients previously treated with a docetaxel-containing treatment regimen.
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidNot Available
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanoneNot Available
PlatensimycinNot Available
TNP-470O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms.
LevomilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults.
(4R)-limoneneLimonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to...
CyclopentamineCyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. It has been widely discontinued due to...
TasimelteonA melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder.
ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
ZeaxanthinZeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some...
PentoxyverineA medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis.
LycopeneAn ingredient found in a variety of supplements and vitamins.
CaramiphenCaramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with phenylpropanolamine, as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal...
TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
GrazoprevirAn antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
CandoxatrilatA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,...
OrtataxelOrtataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
PeficitinibPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
NavarixinNavarixin has been investigated for the treatment of Asthma.
PevonedistatPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
DanoprevirDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
TanzisertibTanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
ArtefenomelArtefenomel has been investigated for the treatment of Malaria.
EsketamineA NMDA receptor antagonist used for treatment-resistant depression.
VaniprevirVaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C...
LomibuvirLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
TesetaxelTesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
AtagabalinAtagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep.
Zuretinol acetateZuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
DiphencyproneDiphencyprone has been used in trials studying the treatment and basic science of Melanoma, Ultraviolet Rays, Immunosuppression, Neoplasm Metastasis, and Hypersensitivity, Delayed, among others.
PF-03654746PF-03654746 has been investigated for the treatment of Narcolepsy, Schizophrenia, Tourette's Syndrome, and Excessive Daytime Sleepiness.
Squaric acid dibutyl esterSquaric acid dibutyl ester is under investigation in clinical trial NCT01971385 (Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis).
LosmapimodLosmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
DasotralineDasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and...
MilataxelMilataxel has been used in trials studying the treatment of Mesothelioma.
PF-03654764PF-03654764 has been used in trials studying the basic science and treatment of Allergic Rhinitis.
ABT-384ABT-384 has been used in trials studying the treatment of Alzheimer's Disease.
MK-5108MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.
AZD-9056AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis.
BMS-188797BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
BMS-184476BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
OpaganibOpaganib, also known as ABC294640, is a selective sphingosine kinase-2 (SK2) ( inhibitor that is orally administered. This drug has potential anticancer, anti-inflammatory, and antiviral activities, with potential applications in...
LarotaxelLarotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others.
AQX-1125AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
LobaplatinLobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
ZidebactamZidebactam is under investigation in clinical trial NCT02674347 (MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous Zidebactam in Healthy Adults).
Fluciclovine (18F)A radiolabelled L-leucine derivative used to image tumors, especially in the prostate.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
GuaiazulenNot Annotated
MotretinideNot Annotated
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
IprindoleNot Annotated
RociverineAn antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms.
EberconazoleNot Annotated
Paclitaxel poliglumexNot Annotated
GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
CyclopropaneCyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery...
13-cis-12-(3'-Carboxyphenyl)retinoic acidNot Annotated
MentholNot Annotated
NarlaprevirNot Annotated
ONO-2952ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome...
MartinostatMartinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
SimotaxelSimotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors).
FucoxanthinFucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). Fucoxanthin isis a marine carotenoid mainly found...
CryptoxanthinNot Annotated
MenthoneA medication used to treat stone formation in the gallbladder and liver.
ChamazuleneNot Annotated
SP-420SP-420 is under investigation in clinical trial NCT03801889 (SP-420 in Subjects With Transfusion-dependent Beta-thalassemia or Other Rare Anemias).
AxomadolAxomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain).
PeretinoinNot Annotated
SelodenosonSelodenoson is under investigation in clinical trial NCT00040001 (Safety and Efficacy Study of an A1-adenosine Receptor Agonist to Slow Heart Rate in Atrial Fibrillation).
ItanapracedNot Annotated
Abscisic AcidNot Annotated
DimethylaminomicheliolideNot Annotated
TPI-287Not Annotated
Paclitaxel ceribateNot Available
GSK-2879552Not Annotated
AbacavirAn antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV.
TranscrocetinateInvestigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
AvoralstatAvoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Abacavir hydroxyacetatePrurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.
JanagliflozinJanagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin).
RuncaciguatNot Annotated
AB-001Not Annotated
ANG1005Not Annotated
GS-100GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence
CC-90001Not Annotated
NerandomilastNot Annotated
Drugs & Drug Targets
Vitamin ARetinol dehydrogenase 12target
Vitamin A11-cis retinol dehydrogenasetarget
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin ARetinal dehydrogenase 1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin AAldehyde dehydrogenase family 1 member A3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin ASerum albumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
TramadolMu-type opioid receptortarget
TramadolSodium-dependent noradrenaline transportertarget
Tramadol5-hydroxytryptamine receptor 2Ctarget
TramadolKappa-type opioid receptortarget
TramadolSodium-dependent serotonin transportertarget
TramadolCytochrome P450 2D6enzyme
TramadolDelta-type opioid receptortarget
TramadolCytochrome P450 3A4enzyme
TramadolCytochrome P450 2B6enzyme
TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
TramadolMuscarinic acetylcholine receptor M3target
TramadolMuscarinic acetylcholine receptor M1target
TramadolUDP-glucuronosyltransferase 1-1enzyme
TramadolNeurokinin 1 receptortarget
TramadolSodium channel protein type 2 subunit alphatarget
TramadolTransient receptor potential cation channel subfamily V member 1target
TramadolNMDA receptortarget
TramadolAdenosine receptor A1target
TramadolAlpha-2 adrenergic receptorstarget
Tranexamic acidPlasminogentarget
AcitretinRetinoic acid receptor alphatarget
AcitretinRetinoic acid receptor RXR-betatarget
AcitretinRetinoic acid receptor gammatarget
AcitretinRetinoic acid receptor betatarget
AcitretinRetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor RXR-alphatarget
AcitretinSerum albumincarrier
AcitretinRetinol-binding protein 1target
AcitretinRetinoic acid receptor RXRtarget
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
AdenosineEquilibrative nucleoside transporter 1transporter
AdenosineEquilibrative nucleoside transporter 2transporter
AdenosineEquilibrative nucleoside transporter 3transporter
AdenosineEquilibrative nucleoside transporter 4transporter
AdenosineSodium/nucleoside cotransporter 1transporter
AdenosineSodium/nucleoside cotransporter 2transporter
AdenosineGap junction alpha-1 proteintransporter
AdenosineAdenylate kinase isoenzyme 1enzyme
AdenosineNucleoside diphosphate kinase Aenzyme
AdenosineNucleoside diphosphate kinase Benzyme
AdenosinePurine nucleoside phosphorylaseenzyme
AdenosineXanthine dehydrogenase/oxidaseenzyme
AdenosineSerum albumincarrier
DicyclomineMuscarinic acetylcholine receptor M1target
DicyclomineMuscarinic acetylcholine receptor M2target
DicyclomineMuscarinic acetylcholine receptor M3target
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinSerum albumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
GabapentinAdenosine receptor A1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
GabapentinLarge neutral amino acids transporter small subunit 1transporter
GabapentinVoltage-dependent N-type calcium channeltarget
GabapentinPotassium voltage-gated channel subfamily KQT member 3target
GabapentinPotassium voltage-gated channel subfamily KQT member 5target
CilastatinDipeptidase 1target
CilastatinSolute carrier family 22 member 6transporter
CilastatinSolute carrier family 22 member 8transporter
VildagliptinDipeptidyl peptidase 4target
VildagliptinP-glycoprotein 1transporter
DesvenlafaxineCytochrome P450 3A4enzyme
DesvenlafaxineSodium-dependent serotonin transportertarget
DesvenlafaxineSodium-dependent noradrenaline transportertarget
DesvenlafaxineCytochrome P450 2D6enzyme
DesvenlafaxineSodium-dependent dopamine transportertarget
DesvenlafaxineUDP-glucuronosyltransferase 1-1enzyme
DesvenlafaxineUDP-glucuronosyltransferase 1-3enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B4enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B15enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B17enzyme
DesvenlafaxineCytochrome P450 2C19enzyme
BromhexineTransmembrane protease serine 2target
BromhexineAngiotensin-converting enzyme 2target
BromhexineAngiotensin-converting enzyme 2enzyme
FumagillinMethionine aminopeptidase 2target
AdamantaneCamphor 5-monooxygenasetarget
ArylacenamideHCG20471, isoform CRA_ctarget
Bisphenol ZEstrogen-related receptor gammatarget
Prephenic acidChorismate mutase AroHtarget
LuteinSerum albumincarrier
VenlafaxineSodium-dependent serotonin transportertarget
VenlafaxineSodium-dependent noradrenaline transportertarget
VenlafaxineCytochrome P450 2D6enzyme
VenlafaxineCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent dopamine transportertarget
VenlafaxineP-glycoprotein 1transporter
VenlafaxineATP-binding cassette sub-family G member 2transporter
VenlafaxineCytochrome P450 2C9enzyme
VenlafaxineCytochrome P450 2C19enzyme
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
PicrotoxinGlycine receptor subunit alpha-2target
PicrotoxinGlycine receptor subunit alpha-3target
PicrotoxinCytochrome P450 1A1enzyme
PicrotoxinGlutamine synthetaseenzyme
PicrotoxinGlycine receptor subunit alpha-1target
MontelukastCysteinyl leukotriene receptor 1target
MontelukastArachidonate 5-lipoxygenasetarget
MontelukastCytochrome P450 3A4enzyme
MontelukastCytochrome P450 2C9enzyme
MontelukastCytochrome P450 2C8enzyme
MontelukastSolute carrier organic anion transporter family member 2B1transporter
MontelukastProstaglandin G/H synthase 1enzyme
MontelukastCytochrome P450 2A6enzyme
HexylcaineSodium channel protein type 5 subunit alphatarget
HexylcaineSodium channel protein type 10 subunit alphatarget
RimantadineMatrix protein 2target
AlitretinoinRetinoic acid receptor alphatarget
AlitretinoinRetinoic acid receptor RXR-betatarget
AlitretinoinRetinoic acid receptor gammatarget
AlitretinoinRetinoic acid receptor betatarget
AlitretinoinRetinoic acid receptor RXR-gammatarget
AlitretinoinRetinoic acid receptor RXR-alphatarget
AlitretinoinCellular retinoic acid-binding protein 2carrier
AlitretinoinCellular retinoic acid-binding protein 1carrier
AlitretinoinP-glycoprotein 1transporter
AlitretinoinInsulin-like growth factor-binding protein 3target
AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
AlitretinoinCytochrome P450 26C1target
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
NateglinideATP-binding cassette sub-family C member 8target
NateglinideCytochrome P450 3A4enzyme
NateglinideCytochrome P450 2C9enzyme
NateglinidePeroxisome proliferator-activated receptor gammatarget
NateglinideCytochrome P450 3A5enzyme
NateglinideCytochrome P450 3A7enzyme
NateglinideSolute carrier family 15 member 1transporter
NateglinideSolute carrier family 15 member 2transporter
NateglinideSolute carrier family 22 member 6transporter
NateglinideMonocarboxylate transporter 1transporter
NateglinideProstaglandin G/H synthase 1enzyme
NateglinideUDP-glucuronosyltransferase 1-9enzyme
NateglinideCytochrome P450 2D6enzyme
NateglinideMultidrug resistance-associated protein 4transporter
NateglinideSerum albumincarrier
NateglinideAlpha-1-acid glycoprotein 1carrier
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCarcinoembryonic antigentarget
TretinoinUDP-glucuronosyltransferase 2B7enzyme
TretinoinCytochrome P450 2E1enzyme
TretinoinCytochrome P450 26A1enzyme
TretinoinCellular retinoic acid-binding protein 1target
SibutramineSodium-dependent serotonin transportertarget
SibutramineSodium-dependent noradrenaline transportertarget
SibutramineCytochrome P450 3A4enzyme
SibutramineSodium-dependent dopamine transportertarget
CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineNitric oxide synthase, braintarget
PaclitaxelApoptosis regulator Bcl-2target
PaclitaxelTubulin beta-1 chaintarget
PaclitaxelCytochrome P450 2C8enzyme
PaclitaxelCytochrome P450 3A4enzyme
PaclitaxelCytochrome P450 3A5enzyme
PaclitaxelCytochrome P450 3A7enzyme
PaclitaxelBile salt export pumptransporter
PaclitaxelP-glycoprotein 1transporter
PaclitaxelMultidrug resistance-associated protein 1transporter
PaclitaxelMultidrug resistance-associated protein 7transporter
PaclitaxelCytochrome P450 19A1enzyme
PaclitaxelCytochrome P450 1B1enzyme
PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
PaclitaxelNuclear receptor subfamily 1 group I member 2target
PaclitaxelMicrotubule-associated protein 4target
PaclitaxelMicrotubule-associated protein 2target
PaclitaxelMicrotubule-associated protein tautarget
PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelApoptosis regulator Bcl-2target
DocetaxelTubulin beta-1 chaintarget
DocetaxelCytochrome P450 3A4enzyme
DocetaxelCytochrome P450 3A5enzyme
DocetaxelCytochrome P450 3A7enzyme
DocetaxelP-glycoprotein 1transporter
DocetaxelMultidrug resistance-associated protein 7transporter
DocetaxelCytochrome P450 1B1enzyme
DocetaxelMicrotubule-associated protein 2target
DocetaxelMicrotubule-associated protein 4target
DocetaxelMicrotubule-associated protein tautarget
DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DocetaxelSolute carrier family 22 member 7transporter
DocetaxelATP-binding cassette sub-family G member 2transporter
DocetaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelMultidrug resistance-associated protein 1transporter
DocetaxelNuclear receptor subfamily 1 group I member 2target
RoflumilastCytochrome P450 3A4enzyme
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)target
RoflumilastCytochrome P450 1A2enzyme
GabaculineOrnithine aminotransferase, mitochondrialtarget
GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
CyclohexanonePentaerythritol tetranitrate reductasetarget
AdamantanoneCamphor 5-monooxygenasetarget
Oseltamivir acidNeuraminidasetarget
Isochorismic AcidPhenazine biosynthesis protein PhzDtarget
Arotinoid acidRetinoic acid receptor betatarget
CyclohexanolAlcohol dehydrogenase 1Btarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
N-EthylretinamideRetinol-binding protein 4carrier
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
CycloleucineGlutamate receptor ionotropic, NMDA 1target
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme
VogliboseMaltase-glucoamylase, intestinaltarget
NeramexaneGlutamate receptor ionotropic, NMDA 3Atarget
ApadenosonAdenosine receptor A2atarget
FenretinideRetinol-binding protein 4carrier
Atl146eAdenosine receptor A2atarget
Paclitaxel docosahexaenoic acidApoptosis regulator Bcl-2target
LGD-1550Retinoic acid receptor alphatarget
LGD-1550Retinoic acid receptor betatarget
LGD-1550Retinoic acid receptor gammatarget
LGD-1550Transcription factor AP-1target
SaxagliptinDipeptidyl peptidase 4target
SaxagliptinCytochrome P450 3A4enzyme
SaxagliptinCytochrome P450 3A5enzyme
SaxagliptinMultidrug resistance-associated protein 1transporter
SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
SaxagliptinSolute carrier family 22 member 8transporter
AR-9281Bifunctional epoxide hydrolase 2target
AstaxanthinNF-kappa-B inhibitor alphatarget
Beta caroteneBeta,beta-carotene 15,15'-dioxygenaseenzyme
Beta caroteneFree radicalstarget
Beta caroteneVery low-density lipoprotein receptorcarrier
Beta caroteneRetinol-binding protein 1carrier
Beta caroteneRetinol-binding protein 2carrier
Beta caroteneRetinol-binding protein 3carrier
Beta caroteneRetinol-binding protein 4carrier
Beta caroteneRetinol-binding protein 5carrier
CabazitaxelCytochrome P450 3A4enzyme
CabazitaxelCytochrome P450 3A5enzyme
CabazitaxelCytochrome P450 2C8enzyme
CabazitaxelP-glycoprotein 1transporter
CabazitaxelATP-binding cassette sub-family G member 2transporter
CabazitaxelTubulin beta-1 chaintarget
CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
CabazitaxelSerum albumincarrier
CabazitaxelLow-density lipoprotein receptorcarrier
CabazitaxelVery low-density lipoprotein receptorcarrier
CabazitaxelGlycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1carrier
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidRetinoic acid receptor gammatarget
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanoneHeme oxygenase 1target
Platensimycin3-oxoacyl-[acyl-carrier-protein] synthase 2target
TNP-470Methionine aminopeptidase 2target
LevomilnacipranCytochrome P450 3A4enzyme
LevomilnacipranCytochrome P450 2C8enzyme
LevomilnacipranCytochrome P450 2C19enzyme
LevomilnacipranCytochrome P450 2D6enzyme
LevomilnacipranCytochrome P450 2J2enzyme
LevomilnacipranSodium-dependent serotonin transportertarget
LevomilnacipranSodium-dependent noradrenaline transportertarget
LevomilnacipranP-glycoprotein 1transporter
TasimelteonMelatonin receptor type 1Atarget
TasimelteonMelatonin receptor type 1Btarget
TasimelteonCytochrome P450 3A4enzyme
TasimelteonCytochrome P450 1A2enzyme
ParitaprevirNS3/4A proteintarget
ParitaprevirCytochrome P450 3A4enzyme
ParitaprevirCytochrome P450 3A5enzyme
ParitaprevirATP-binding cassette sub-family G member 2transporter
ParitaprevirP-glycoprotein 1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
ParitaprevirUDP-glucuronosyltransferase 1-1enzyme
PentoxyverineSigma non-opioid intracellular receptor 1target
PentoxyverinePotassium voltage-gated channel subfamily H member 2target
PentoxyverineVoltage-gated sodium channel alpha subunittarget
PentoxyverineKappa-type opioid receptortarget
PentoxyverineMu-type opioid receptortarget
GrazoprevirP-glycoprotein 1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B3transporter
GrazoprevirCytochrome P450 3A4enzyme
GrazoprevirNS3/4A proteintarget
GrazoprevirSerum albumincarrier
GrazoprevirAlpha-1-acid glycoprotein 1carrier
DanoprevirGenome polyproteintarget
DanoprevirCytochrome P450 3A4enzyme
EsketamineNMDA receptortarget
EsketamineCytochrome P450 2B6enzyme
EsketamineCytochrome P450 3A4enzyme
EsketamineCytochrome P450 2C19enzyme
EsketamineCytochrome P450 2C9enzyme
EsketamineGlutamate receptor ionotropic, NMDA 2Btarget
EsketamineElongation factor 2target
EsketamineBrain-derived neurotrophic factortarget
EsketamineBDNF/NT-3 growth factors receptortarget
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
DasotralineSodium-dependent dopamine transportertarget
DasotralineSodium-dependent serotonin transportertarget
DasotralineSodium-dependent noradrenaline transportertarget
MilataxelTubulin beta-1 chaintarget
MilataxelTubulin beta chaintarget
MK-5108Aurora kinase Atarget
OpaganibSphingosine kinase 2target
Fluciclovine (18F)Neutral amino acid transporter B(0)target
Fluciclovine (18F)Y+L amino acid transporter 1target
Fluciclovine (18F)Cationic amino acid transporter 3target
Fluciclovine (18F)Glutamate (NMDA) receptortarget
Fluciclovine (18F)Glutamate receptor 1target
Fluciclovine (18F)Glutamate receptor 2target
Fluciclovine (18F)Glutamate receptor 3target
Fluciclovine (18F)Glutamate receptor 4target
Fluciclovine (18F)Multidrug resistance-associated protein 4transporter
BencyclaneCytochrome P450 3A4enzyme
RociverineMuscarinic acetylcholine receptor M1target
RociverineMuscarinic acetylcholine receptor M2target
RociverineMuscarinic acetylcholine receptor M3target
RociverineMuscarinic acetylcholine receptor M4target
RociverineMuscarinic acetylcholine receptor M5target
GlecaprevirCytochrome P450 3A Subfamilyenzyme
GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
GlecaprevirP-glycoprotein 1transporter
GlecaprevirATP-binding cassette sub-family G member 2transporter
GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirNS3 proteasetarget
GlecaprevirCytochrome P450 3A4enzyme
GlecaprevirNS3/4A proteintarget
MentholTransient receptor potential cation channel subfamily M member 8target
AbacavirAlcohol dehydrogenase 6enzyme
AbacavirUDP-glucuronosyltransferase 1-1enzyme
AbacavirReverse transcriptase/RNaseHtarget
AbacavirAdenosine kinaseenzyme
AbacavirHLA class I histocompatibility antigen, B-57 alpha chaintarget