Sweetening Agents

Name
Sweetening Agents
Accession Number
DBCAT000378
Description

Substances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)

Drugs
DrugDrug Description
AspartameUsed as a diet supplement and sugar substitute.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
SucroseA nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as...
MaltoseA sugar used as a sweetener and an inactive ingredient in drug products.
FructoseNot Available
LactoseAn additive and filler found in various products to maintain structure and consistency.
SC45647Not Available
Invert sugarInvert sugar presents a large variety of uses. It can be used therapeutically for parenteral hyperalimentation or to be used as an excipient with a known effect. Invert sugar is...
XylitolAn ingredient added to dental products to remove bacteria.
SaccharinA non-nutritive artificial sweetener for sweetening foods and drinks.
SteviolbiosideSteviolbioside has been used in trials studying the treatment of HIV-1 Infection.
AV-101AV-101 has been used in trials studying the treatment of Neuropathic Pain.
LactitolAn orally administered osmotic laxative used to treat chronic idiopathic constipation.
D-glucoseA most commonly occurring isomer of glucose used as a carbohydrate supplementation in case of nutrient deprivation and metabolic disorders, such as hypoglycemia.
SucraloseSucralose is an artificial sweetener used as a sugar substitute.
Rebaudioside ARebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
LevoglucoseLevoglucose has been used in trials studying the diagnostic of Bowel Cleansing Prior to Colonoscopy.
MaltitolNot Annotated
AcesulfameNot Annotated
SteviosideNot Annotated
Drugs & Drug Targets
DrugTargetType
AspartameTaste receptor type 1 member 2target
AspartameTransient receptor potential cation channel subfamily V member 1target
AspartameSolute carrier family 22 member 6transporter
AspartameSolute carrier family 22 member 8transporter
AspartameSolute carrier family 22 member 11transporter
AspartameTaste receptor type 1 member 3target
MannitolMannitol dehydrogenaseenzyme
SucroseBeta-lactamasetarget
SucroseLysozyme Ctarget
SucroseActin, alpha skeletal muscletarget
SucroseBeta-glucosidasetarget
SucroseAmylosucrasetarget
SucroseBeta-lactamasetarget
SucroseBeta-lactamase CTX-Mtarget
SucroseHeme oxygenasetarget
SucroseCopper transport protein ATOX1target
SucrosetRNA-splicing ligase RtcB homologtarget
SucroseOrange carotenoid-binding proteintarget
SucroseSucrose porintarget
SucroseLevansucrasetarget
SucroseTaste receptor type 1 member 2target
MaltoseCyclomaltodextrin glucanotransferasetarget
MaltoseAlpha-amylase 2Btarget
MaltoseBeta-amylasetarget
MaltoseMaltogenic alpha-amylasetarget
MaltoseMaltodextrin phosphorylasetarget
MaltoseMaltose-binding periplasmic proteintarget
MaltoseAlpha-glucosidasetarget
MaltoseMaltose binding proteintarget
MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
FructoseMaltoporintarget
LactoseBeta-galactosidasetarget
LactoseGlycosyltransferase 6 domain-containing protein 1target
LactoseGlycolipid transfer proteintarget
LactoseHydrolasetarget
LactoseEndo-1,4-beta-xylanase Atarget
LactoseGalectin-3target
LactoseSialidasetarget
LactoseBeta-galactosidasetarget
Invert sugarSolute carrier family 2, facilitated glucose transporter member 2transporter
Invert sugarSolute carrier family 2, facilitated glucose transporter member 5transporter
Invert sugarGlucokinaseenzyme
Invert sugar6-phosphofructokinaseenzyme
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolHyaluronate lyasetarget
SaccharinCarbonic anhydrase 3target
D-glucoseHexokinase-1enzyme
D-glucoseGlucokinaseenzyme
D-glucoseSolute carrier family 2, facilitated glucose transporter member 1transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 2transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 3transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 4transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 5transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 6transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 7transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 8transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 9transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 10transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 11transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 12transporter
D-glucoseSodium/glucose cotransporter 1transporter
D-glucoseSodium/glucose cotransporter 2transporter
D-glucoseSerum albumincarrier