Name
Catechols
Accession Number
DBCAT000419
Description

A group of 1,2-benzenediols that contain the general formula R-C6H5O2.

Drugs
DrugDrug Description
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
CarbidopaA dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
AlprazolamA triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
MethyldopaA centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises.
IsoprenalineA catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block.
LevodopaA dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.
Fluorodopa (18F)Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes...
GuaiacolIt is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a...
CurcuminNo approved therapeutic indications.
AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
4-VinylguaiacolNot Available
6-hydroxydopa quinoneNot Available
DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
EtilevodopaInvestigated for use/treatment in parkinson's disease.
LevonordefrinA topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
RacepinephrineA bronchodilator used to treat intermittent asthma.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
TerameprocolTerameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
DichloroisoproterenolDichloroisoproterenol has been used in trials studying the treatment and basic science of Insulin Resistance and Polycystic Ovary Syndrome.
ReproterolA short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma.
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
MelevodopaA methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease.
IbopamineA sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia.
AdrenaloneNot Annotated
Potassium guaiacolsulfonateA mucolytic and expectorant indicated to relieve a productive cough.
DeoxyepinephrineSympathomimetic, vasoconstrictor agent.
J147J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic...
DihydrocapsiateDihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
ZingeroneZingerone is a pungent component of ginger.
DopastatinDopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
ASC-JM-17Not Annotated
N-oleoyldopamineN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.
DocarpamineNot Available
Drugs & Drug Targets
DrugTargetType
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolSex hormone-binding globulintarget
MasoprocolTransient receptor potential cation channel subfamily M member 7target
MethocarbamolCarbonic anhydrase 1target
GuaifenesinNMDA receptortarget
CarbidopaAromatic-L-amino-acid decarboxylasetarget
AlprazolamCytochrome P450 3A4enzyme
AlprazolamCytochrome P450 2C9enzyme
AlprazolamCytochrome P450 3A5enzyme
AlprazolamCytochrome P450 3A7enzyme
AlprazolamGABA(A) Receptortarget
AlprazolamSerum albumincarrier
Alprazolamalpha1-acid glycoproteincarrier
AlprazolamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
MethyldopaSerum albumincarrier
MethyldopaSulfotransferaseenzyme
MethyldopaDopamine beta-hydroxylaseenzyme
MethyldopaPhenylethanolamine N-methyltransferaseenzyme
MethyldopaAromatic-L-amino-acid decarboxylaseenzyme
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineSuperoxide dismutase [Cu-Zn]target
IsoprenalineCytochrome P450 1B1enzyme
IsoprenalineSerum albumincarrier
IsoprenalineCatechol O-methyltransferaseenzyme
IsoprenalineCholinesteraseenzyme
LevodopaDopamine D1 receptortarget
LevodopaDopamine D2 receptortarget
LevodopaAromatic-L-amino-acid decarboxylaseenzyme
LevodopaSolute carrier family 15 member 1transporter
LevodopaMonocarboxylate transporter 10transporter
LevodopaDopamine D3 receptortarget
LevodopaDopamine D4 receptortarget
LevodopaDopamine D5 receptortarget
LevodopaLarge neutral amino acids transporter small subunit 1transporter
LevodopaLarge neutral amino acids transporter small subunit 2transporter
LevodopaSerum albumincarrier
Fluorodopa (18F)Aromatic-L-amino-acid decarboxylaseenzyme
GuaiacolSerum albumintarget
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
AmphetamineSodium-dependent dopamine transportertarget
AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
AmphetamineTrace amine-associated receptor 1target
AmphetamineCytochrome P450 2D6enzyme
AmphetamineSolute carrier family 22 member 3transporter
AmphetamineSolute carrier family 22 member 5transporter
AmphetamineSynaptic vesicular amine transportertarget
AmphetamineCytochrome P450 2A6enzyme
AmphetamineSodium-dependent noradrenaline transportertarget
AmphetamineAlpha adrenergic receptortarget
AmphetamineBeta adrenergic receptortarget
AmphetamineDopamine D2 receptortarget
AmphetamineAmine oxidase [flavin-containing] Btarget
AmphetamineSodium-dependent serotonin transportertarget
AmphetamineMonoamine oxidasetarget
Amphetaminevesicular monoamine transporter 2 (VMAT2)target
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
OrciprenalineBeta-2 adrenergic receptortarget
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptor alphatarget
DopamineDopamine D1 receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineSolute carrier family 22 member 5transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineDopamine D5 receptortarget
DopamineDopamine D2 receptortarget
DopamineDopamine D3 receptortarget
DopamineDopamine D4 receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
ArbutamineBeta-1 adrenergic receptortarget
ArbutamineBeta-2 adrenergic receptortarget
ArbutamineBeta-3 adrenergic receptortarget
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
6-hydroxydopa quinoneMembrane primary amine oxidasetarget
6-hydroxydopa quinonePrimary amine oxidasetarget
6-hydroxydopa quinonePhenylethylamine oxidasetarget
DroxidopaPhenylalanine-4-hydroxylasetarget
DroxidopaAlpha-1A adrenergic receptortarget
DroxidopaAlpha-1B adrenergic receptortarget
DroxidopaAlpha-1D adrenergic receptortarget
DroxidopaAlpha-2A adrenergic receptortarget
DroxidopaAlpha-2B adrenergic receptortarget
DroxidopaAlpha-2C adrenergic receptortarget
DroxidopaBeta-1 adrenergic receptortarget
DroxidopaBeta-2 adrenergic receptortarget
DroxidopaBeta-3 adrenergic receptortarget
DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DroxidopaMonocarboxylate transporter 10transporter
DroxidopaSodium-dependent noradrenaline transportertransporter
LevonordefrinAlpha-2 adrenergic receptorstarget
ProtokylolBeta-2 adrenergic receptortarget
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
NonivamideTransient receptor potential cation channel subfamily V member 1target