Phenols
- Name
- Phenols
- Accession Number
- DBCAT000420
- Description
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
- Drugs
Drug Drug Description Mesalazine An aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved. Tolcapone A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. Methocarbamol A CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions. Entacapone A selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Proparacaine A topical anesthetic used for ophthalmic practice. Propofol A medication used in general anesthesia and for sedation. Guaifenesin An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses. Dienestrol A non steroidal estrogen used to treat atrophic vaginitis and kraurosis vulvae. Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Bismuth subsalicylate An antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. Probucol Used to lower LDL and HDL cholesterol. Phenol An antiseptic and disinfectant used in a variety of settings. Bithionol Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Triclosan An antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew. Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. Bisacodyl A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. Phloroglucinol A spasmolytic agent to treat colic, as well as spastic pain of the digestive and biliary tracts. Carbidopa A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Tapentadol An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. Fluorodopa (18F) Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes... Anethole An excipient added to medications for flavouring. Haloprogin Used to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor. Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Olsalazine An anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis. Magnesium salicylate An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. Salsalate A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. 2-Aminophenol Not Available 2,4-Dihydroxybenzoic Acid Not Available KB-141 An anticholesteremic agent. 3,4-Dihydroxybenzoic Acid Not Available Balanol Not Available Tesmilifene Intended for the treatment of various forms of cancer. Vernakalant An antiarrhythmic medication used to treat patients with atrial fibrillation. Dersalazine Investigated for use/treatment in inflammatory bowel disease. BNC105 Investigated for use/treatment in cancer/tumors (unspecified). Phenyl aminosalicylate Not Annotated Andarine Andarine is a non-steroidal selective androgen receptor modulator. Triflusal A medication related to acetylsalicylic acid with antithrombotic effects used in the treatment of thromboembolic diseases. Mequinol A topical agent used in combination with tretinoin to treat solar lentigines. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Octisalate Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer. Homosalate As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer. Phenyl salicylate Pain and fever . Trolamine salicylate A medication used to relieve minor aches and pains of the muscles and joints. Diethylamino hydroxybenzoyl hexyl benzoate Indicated for use as a sunscreen agent. Glycol salicylate A salicylate used to treat mild to moderate muscle pain. Vixotrigine Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Lifibrol Lifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia. Emixustat Emixustat has been used in trials studying the treatment of Geographic Atrophy, Age-Related Macular Degeneration, and Dry Age-related Macular Degeneration. Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. 4-dimethylaminophenol Not Annotated Benorilate Not Annotated Anethole trithione A medication used to treat dry mouth associated with medication or radiotherapy of the head and neck. Nifuroxazide An antibiotic indicated in the treatment of susceptible gastrointestinal infections. Imidazole salicylate Not Annotated Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Thiosalicylic acid Not Annotated p-Aminophenol Not Annotated PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). Ampreloxetine Ampreloxetine is under investigation in clinical trial NCT03750552 (Clinical Effect of TD-9855 for Treating snOH in Subjects With Primary Autonomic Failure). Ethyl salicylate A salicylate indicated in the treatment of sports related pain. Masoprocol Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated). Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Monobenzone A hydroquinone derivative used to treat vitiligo. Clofibrate A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Hexachlorophene A chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser. Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Diflunisal An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Balsalazide An aminosalicylate used to treat ulcerative colitis. Tolterodine A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. Arbutamine Used to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in... Fenoterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. p-Hydroxymercuribenzoic acid Not Available P-Cresol Not Available M-Cresol Not Available 4-Nitrocatechol sulfate Not Available Hyperforin Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also... 3-Chlorophenol Not Available 3,5-Dinitrocatechol Not Available Vanillic acid A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). 1,2-Dihydroxybenzene Not Available Thymol An essential oil found in various over-the-counter antibacterial and antifungal products. Resveratrol Being investigated for the treatment of Herpes labialis infections (cold sores). P-Anisic Acid Not Available IC261 Not Available 2-Chlorophenol Not Available 4-Nitrocatechol Not Available 4-Vinylguaiacol Not Available Picric acid Used as antiseptic, astringent, and stimulant for epitheliazation. 2-Nitro-4-cresol Not Available 4-Nitrophenyl Phosphate Not Available 4-hydroxybenzoic acid Not Available 6-hydroxydopa quinone Not Available P-Nitrophenol Not Available 2,4-Dinitrophenol A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,... 2-Amino-4-methylphenol Not Available 2,5-di-tert-butylhydroquinone Not Available Phenolphthalein A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. Permethrin An insecticide used to prevent infestation with Sarcoptes scabiei (scabies). Succinobucol Investigated for use/treatment in atherosclerosis, coronary artery disease, diabetes mellitus type 2, and in-stent restenosis. Tapinarof A therapeutic aryl hydrocarbon receptor-modulating agent (TAMA) indicated for the treatment of adult psoriasis. Cenobamate A small molecule drug indicated to treat partial onset seizures in adults. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Etilevodopa Investigated for use/treatment in parkinson's disease. Levonordefrin A topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures. Fospropofol A sedative-hypnotic agent indicated for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Protokylol Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. t-Butylhydroquinone Not Available Phloretin Phloretin is a natural dihydrochalcone found in apples and many other fruits. Hypothemycin Not Available Methyl vanillate Not Available Etofibrate Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. Bromopride A substituted benzamide, closely related to metoclopramide, used as an antiemetic. Ciprofibrate Not Annotated Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Efonidipine For the treatment of hypertension. Hydroquinone A topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. Resorcinol Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin... Racepinephrine A bronchodilator used to treat intermittent asthma. Cresol A dental disinfectant used to remove dental pulp. Hexylresorcinol An ingredient used to relieve irritation, pain, and prevent infection. Protocatechualdehyde Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza . Protocatechualdehyde... Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Guaiacol It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a... Dichlorophen Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from... Zeranol Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x... Curcumin No approved therapeutic indications. AUY922 AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others. HX-1171 Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety, Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects). Terameprocol Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors. Dopexamine Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. Nitroaspirin Nitroaspirin has been investigated for the treatment of Intermittent Claudication. Propyl Gallate Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects). Dichloroisoproterenol Dichloroisoproterenol has been used in trials studying the treatment and basic science of Insulin Resistance and Polycystic Ovary Syndrome. Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma. Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Parachlorophenol An antibacterial agent used to prevent infections in root canals. Phenolsulfonphthalein Phenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions... Sulfobromophthalein Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans . Clofoctol An antibacterial agent indicated in the treatment of respiratory infections; or prevention of infections after ear, nose, and throat surgery. Hexobendine Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has... Wood creosote Not Annotated Bucetin Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication. Melevodopa A methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease. Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Adrenalone Not Annotated Simfibrate Not Annotated Cyclofenil Not Annotated Policresulen Not Annotated Aloxiprin Not Annotated Clefamide Not Annotated Guacetisal Not Annotated Rimiterol Not Annotated Carbaspirin calcium An NSAID indicated in the treatment of short term pain and fever. Ethyl hydroxybenzoate Not Annotated Potassium guaiacolsulfonate A mucolytic and expectorant indicated to relieve a productive cough. Bibrocathol Not Annotated Clofibride Not Annotated Hemoglobin crosfumaril Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. Fenofibric acid A fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. Amylmetacresol An antiseptic used to treat infections in the mouth and throat. Bismuth subgallate A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery. Deoxyepinephrine Sympathomimetic, vasoconstrictor agent. Diclofop-methyl Herbicide for control of wild oat & foxtails in cereal crops. J147 J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic... Butylparaben Not Annotated Phenylethyl resorcinol A tyrosinase inhibitor with skin-lightening activity. Benzylparaben Benzylparaben is used in allergenic testing. Propylparaben Propylparaben is used in allergenic testing. Methylparaben Methylparaben is used in allergenic testing. Deacetylbisacodyl Not Annotated Dienestrol diacetate Not Annotated Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). Resorcinol monoacetate Not Annotated Zingerone Zingerone is a pungent component of ginger. 1,3,5-Trimethoxybenzene A medication indicated for the symptomatic treatment of spastic pain of the urinary tract, renal colic, and painful disorders of the digestive and biliary tract. Dopastatin Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). Thyme oil Not Annotated Lavendustin b Not Annotated WZB-117 Not Annotated Butylated hydroxytoluene Not Annotated Chlorocresol Not Annotated Rosmarinic acid Not Annotated ASC-JM-17 Not Annotated ABT-737 An inhibitor of members of the Bcl‑2 family of apoptosis regulators. N-oleoyldopamine N-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid. Tannic acid Tannic acid is indicated for cold sores, fever blisters, diaper rash, minor burn or sunburn and prickly heat. Vaginally, tannic acid is used as a douche for leukorrhea. It has... Acteoside Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy). Mesdopetam Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia). Pocapavir Not Annotated Docarpamine Not Available Crisdesalazine Not Annotated - Drugs & Drug Targets