Aminobutyrates
- Name
- Aminobutyrates
- Accession Number
- DBCAT000424
- Description
Derivatives of BUTYRIC ACID that contain one or more amino groups attached to the aliphatic structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobutryrate structure.
- ATC Classification
- Drugs
Drug Drug Description Baclofen A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients. Pregabalin An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. Gabapentin An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. Vigabatrin An irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. gamma-Aminobutyric acid The most common inhibitory neurotransmitter in the central nervous system. 2-aminoisobutyric acid Not Available Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Progabide Indicated for the treatment of epilepsy. BL-1020 Investigated for use/treatment in schizophrenia and schizoaffective disorders. Gabapentin enacarbil A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Arbaclofen Placarbil Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. PD-217014 PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome. Pivagabine Pivagabine has been used in trials studying the treatment of Stress and Anxiety. Phenibut Not Annotated Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Gamma-amino-beta-hydroxybutyric acid An anticonvulsant indicated to treat convulsions in children and epilepsy. - Drugs & Drug Targets