Name
Alkaloids
Accession Number
DBCAT000443
Description

Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)

Drugs
DrugDrug Description
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
ReserpineFor the treatment of hypertension
BenzatropineAn anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
CabergolineA dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
MorphineAn opioid agonist used for the relief of moderate to severe acute and chronic pain.
VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
HydromorphoneAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
HyoscyamineAn anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
OxycodoneAn opioid used in the management of moderate to severe pain.
DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
LisurideFor the management of Parkinson's Disease
GalantamineA cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
ScopolamineA belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).
IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
HydrocodoneAn opioid agonist used as an analgesic and antitussive agent.
DimenhydrinateA medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
PilocarpineA muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
NaloxoneAn opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
PergolideA long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy.
TubocurarineTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
ColchicineAn alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.
TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
ArecolineAn alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the...
CamptothecinInvestigated for the treatment of cancer.
Omacetaxine mepesuccinateA cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
NoscapineA non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category...
DrotaverineA phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
HomatropineAn anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough.
VinflunineA vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
ZalypsisZalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others.
SamidorphanA novel opioid-system modulator, similar to naltrexone, that functions primarily as a μ-opioid receptor antagonist in vivo and is used primarily in combination with antipsychotics to reduce their metabolic dysfunction-associated adverse effects.
Sacituzumab govitecanSacituzumab govitecan targets TROP-2-expressing cancer cells through a humanized antibody (RS7) before subsequently becoming internalized and releasing the topoisomerase I inhibitor SN-38 to induce DNA damage-mediated apoptosis.
EmetineNot Annotated
ColchiceineColchiceine is one of several metabolites of the anti-gout medication colchicine.
Variolin BNot Available
1-deoxymannojirimycinAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]
beta-IsosparteineNot Annotated
AjmalineAn antiarrhythmic used to manage a variety of forms of tachycardias.
K-252aNot Available
LobelineInvestigated for use/treatment in addictions.
Rauwolfia serpentina rootRauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics...
MetoserpateNot Annotated
AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
TetrandrineNot Annotated
RaubasineNot Annotated
NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
MethysergideAn ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
MethylergometrineAn ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery.
Metocurine iodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
Methscopolamine bromideA muscarinic antagonist used to treat peptic ulcers, nausea, vomiting, and motion sickness.
MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
LevallorphanFor the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.
Anisotropine methylbromideFor use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.
ButorphanolAn opioid agonist-antagonist used to treat moderate to severe pain.
PentazocineAn analgesic used to treat moderate to severe pain.
ErgotamineAn alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
NicergolineAn ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities.
NaltrexoneA narcotic antagonist used in opioid overdose.
Homatropine methylbromideA muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
CryptenamineFor the treatment of hypertension.
EnprofyllineUsed in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
NalbuphineAn opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery.
LevorphanolAn opioid analgesic used to treat moderate to severe pain.
BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
PhysostigmineA cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
DeserpidineAn alkaloid that has been used to manage hypertension.
RescinnamineFor the treatment of hypertension.
OxymorphoneAn opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
BromocriptineA dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
ErgometrineAn ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony.
OxtriphyllineA bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
MetocurineMetocurine is a muscle relaxant.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
AlmitrineFor the treatment of chronic obstructive pulmonary disease.
5-Methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
DihydroetorphineNot Available
DiamorphineAn opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema.
EthylmorphineAn opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine.
CyprenorphineNot Available
FenethyllineNot Available
EtorphineEtorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals.
BenzoylecgonineBenzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after...
EcgonineNot Available
DesomorphineNot Available
DrotebanolNot Available
DiprenorphineDiprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans.
DihydrocodeineAn opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
DihydromorphineDihydromorphine is an opioid analgesic used for moderate to severe pain relief.
TropinoneNot Available
8-azaxanthineNot Available
7-HydroxystaurosporineNot Available
StaurosporineAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
XanthineA drug used to manage uncomplicated liver dysfunction in combination with orotic acid.
DeacetoxyvinzolidineNot Available
PseudotropineNot Available
BerberineAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal...
Calystegine B2Not Available
MethylecgonineNot Available
Lysergic acid diethylamideDebate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
VoacamineFor the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells.
PhenserineFor the treatment of Alzheimer's disease (AD).
AltropaneInvestigated for use/treatment in attention deficit/hyperactivity disorder (ADHD), parkinson's disease, and pediatric indications.
MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
VintafolideInvestigated for use/treatment in solid tumors.
SN-38Investigated for use/treatment in colorectal cancer.
NS-2359Investigated for use/treatment in addictions, attention deficit/hyperactivity disorder (ADHD), and depression.
CositecanInvestigated for use/treatment in brain cancer, lung cancer, and melanoma.
RivaniclineInvestigated for use/treatment in ulcerative colitis.
EP0057Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
XMT-1001Investigated for use/treatment in solid tumors.
RubitecanInvestigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
NalmefeneAn opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose.
Morphine glucuronideInvestigated for use/treatment in pain (acute or chronic).
NaxifyllineInvestigated for use/treatment in congestive heart failure.
PropentofyllineInvestigated for use/treatment in alzheimer's disease.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
GimatecanGimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
MethylnaltrexoneA μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
HarmineNot Available
Ioflupane I-123A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes.
Uric acidAt present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke.
AclidiniumAn inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD).
FentoniumFentonium is an atropine derivative.
NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
PholcodineAn opioid antitussive used to suppress unproductive coughing.
CimetropiumCimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which...
DoxofyllineA methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms.
ButylscopolamineAn antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
DihydroergocornineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
EpicriptineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
MethscopolamineMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The...
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
NalorphineUsed to reverse opioid overdose.
BicucullineBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and...
ThiocolchicosideA semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory.
PsilocybinPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
NaldemedineAn opioid antagonist used to to treat opioid-induced constipation.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
AxelopranAxelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
OrantinibOrantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
OxitropiumOxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
NamitecanNamitecan has been used in trials studying the treatment of Solid Tumors.
VinpocetineA synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
ExatecanExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
LurtotecanLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
MoxaverineMoxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
SilatecanSilatecan has been used in trials studying the treatment of GBM, Tumors, Gliosarcoma, Solid Malignancies, and Glioblastoma Multiforme, among others.
10-hydroxycamptothecin10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
BelotecanBelotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
9-aminocamptothecinAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
TonapofyllineTonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
PatidegibPatidegib has been investigated for the treatment of Conventional Chondrosarcoma.
RolofyllineRolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
SolamargineSolamargine has been used in trials studying the treatment of Actinic Keratosis.
PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
ReproterolA short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma.
CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DPCPXCPX has been used in trials studying the treatment of Cystic Fibrosis.
CT-2584CT-2584 has been used in trials studying the treatment of Prostate Cancer.
Ambroxol acefyllinateA bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm.
BamifyllineA methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm.
DemecolcineNot Annotated
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
DihydroergocryptineA dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis.
TergurideNot Annotated
ProxyphyllineNot Annotated
NicomorphineNot Annotated
DeptropineNot Annotated
EtybenzatropineNot Annotated
NalfurafineNot Annotated
TenidapNot Annotated
MetergolineAn ergot-derivative that acts as an antagonist at certain 5-HT receptor subtypes and as an agonist at dopamine receptors. It is often used in situations where inhibition of prolactin is desirable.
PrajmalineNot Annotated
AcefyllineNot Annotated
BietaserpineNot Annotated
EtamiphyllineNot Annotated
PhenazocineNot Annotated
PentifyllineNot Annotated
LorajmineNot Annotated
HydroquinineNot Annotated
VinburnineNot Annotated
DimemorfanNot Annotated
BufyllineNot Annotated
MethylatropineNot Annotated
DehydroemetineNot Annotated
HarmalineNot Annotated
BromotheophyllineBromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
FurafyllineFurafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
8-chlorotheophyllineWhen used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
LoxicodegolLoxicodegol was developed as an opioid analgesic with low abuse potential for use in treating chronic pain . An application has been filed for FDA approval of Loxicodegol for use...
DextrorphanNot Annotated
PF-232798PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
Firtecan pegolFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
18-methoxycoronaridine18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
HydroquinidineA medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm.
PosiphenPosiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
DihydrocapsiateDihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
StrychnineNot Annotated
ButropiumA medication indicated to treat pain caused by gastrointestinal inflammation and ulcers, or diseases of the gallbladder.
DiflomotecanDiflomotecan is under investigation in clinical trial NCT00080015 (Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC)).
NazartinibNazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).
DihydroergotoxineNot Annotated
CepharanthineNot Annotated
CinchonidineNot Annotated
SinomenineNot Annotated
Ioflupane F-18Not Annotated
ChelerythrineA benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
EllipticineEllipticine is a potent antineoplastic agent.
SolasonineNot Annotated
Ukrain cationNot Annotated
DRF-1042Not Annotated
LipotecanNot Annotated
Gibberellic acidNot Available
Gibberellin A4Not Available
CytisineAn alkaloid with partial agonist activity at the α4β2 nicotinic acetylcholine receptor used to aid smoking cessation.
Salvinorin ASalvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
SteviolbiosideSteviolbioside has been used in trials studying the treatment of HIV-1 Infection.
Rebaudioside ARebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
OxymatrineOxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).
IsosteviolNot Annotated
SteviosideNot Annotated
IntermedineNot Annotated
N-9-MethoxynonyldeoxynojirimycinNot Annotated
LomifyllineNot Annotated
BerbamineNot Annotated
Drugs & Drug Targets
DrugTargetType
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
ReserpineSynaptic vesicular amine transportertarget
ReserpineP-glycoprotein 1transporter
ReserpineSolute carrier family 22 member 1transporter
ReserpineBile salt export pumptransporter
ReserpineCanalicular multispecific organic anion transporter 1transporter
ReserpineSolute carrier family 22 member 2transporter
ReserpineCytochrome P450 3A5enzyme
ReserpineChromaffin granule amine transportertarget
ReserpineBaculoviral IAP repeat-containing protein 5target
ReserpineSolute carrier organic anion transporter family member 1B1transporter
ReserpineSolute carrier organic anion transporter family member 2B1transporter
BenzatropineMuscarinic acetylcholine receptor M1target
BenzatropineSodium-dependent dopamine transportertarget
BenzatropineHistamine H1 receptortarget
BenzatropineSerum albumincarrier
BenzatropineSodium-dependent serotonin transportertarget
BenzatropineSodium-dependent noradrenaline transportertarget
CabergolineDopamine D2 receptortarget
Cabergoline5-hydroxytryptamine receptor 2Btarget
CabergolineDopamine D3 receptortarget
Cabergoline5-hydroxytryptamine receptor 2Atarget
CabergolineAlpha-2B adrenergic receptortarget
Cabergoline5-hydroxytryptamine receptor 1Dtarget
CabergolineDopamine D4 receptortarget
CabergolineAlpha-2A adrenergic receptortarget
Cabergoline5-hydroxytryptamine receptor 1Atarget
CabergolineAlpha-2C adrenergic receptortarget
CabergolineDopamine D5 receptortarget
CabergolineDopamine D1 receptortarget
Cabergoline5-hydroxytryptamine receptor 1Btarget
Cabergoline5-hydroxytryptamine receptor 2Ctarget
CabergolineCytochrome P450 3A4enzyme
Cabergoline5-hydroxytryptamine receptor 7target
CabergolineAlpha-1A adrenergic receptortarget
CabergolineAlpha-1B adrenergic receptortarget
CabergolineAlpha-1D adrenergic receptortarget
CabergolineBeta-1 adrenergic receptortarget
CabergolineBeta-2 adrenergic receptortarget
CabergolineD(1) dopamine receptortarget
CabergolineP-glycoprotein 1transporter
MorphineMu-type opioid receptortarget
MorphineDelta-type opioid receptortarget
MorphineKappa-type opioid receptortarget
MorphineP-glycoprotein 1transporter
MorphineCytochrome P450 2C8enzyme
MorphineCytochrome P450 3A4enzyme
MorphineUDP-glucuronosyltransferase 2B7enzyme
MorphineUDP-glucuronosyltransferase 1-1enzyme
MorphineUDP-glucuronosyltransferase 1-8enzyme
MorphineUDP-glucuronosyltransferase 2B15enzyme
MorphineUDP-glucuronosyltransferase 2B4enzyme
MorphineUDP-glucuronosyltransferase 1-3enzyme
MorphineLymphocyte antigen 96target
MorphineSerum albumincarrier
VindesineTubulin beta-1 chaintarget
VindesineCytochrome P450 3A4enzyme
CodeineMu-type opioid receptortarget
CodeineDelta-type opioid receptortarget
CodeineKappa-type opioid receptortarget
CodeineCytochrome P450 2D6enzyme
CodeineCytochrome P450 3A4enzyme
CodeineSolute carrier family 22 member 1transporter
CodeineUDP-glucuronosyltransferase 2B7enzyme
CodeineUDP-glucuronosyltransferase 2B4enzyme
Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DihydroergotamineCytochrome P450 3A4enzyme
DihydroergotamineAlpha-2A adrenergic receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DihydroergotamineP-glycoprotein 1transporter
Dihydroergotamine5-hydroxytryptamine receptor 1Atarget
Dihydroergotamine5-hydroxytryptamine receptor 1Etarget
Dihydroergotamine5-hydroxytryptamine receptor 2Atarget
Dihydroergotamine5-hydroxytryptamine receptor 2Ctarget
DihydroergotamineAlpha-1 adrenergic receptorstarget
DihydroergotamineAlpha-2 adrenergic receptorstarget
DihydroergotamineDopamine D2 receptortarget
DihydroergotamineDopamine D3 receptortarget
DihydroergotamineDopamine D4 receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 1Ftarget
Dihydroergotamine5-hydroxytryptamine receptor 4target
DihydroergotamineBeta-3 adrenergic receptortarget
HydromorphoneMu-type opioid receptortarget
HydromorphoneDelta-type opioid receptortarget
HydromorphoneKappa-type opioid receptortarget
HydromorphoneCytochrome P450 2C9enzyme
HydromorphoneUDP-glucuronosyltransferase 1-3enzyme
HydromorphoneUDP-glucuronosyltransferase 2B7enzyme
HydromorphoneSerum albumincarrier
IpratropiumMuscarinic acetylcholine receptor M1target
IpratropiumMuscarinic acetylcholine receptor M2target
IpratropiumMuscarinic acetylcholine receptor M3target
IpratropiumSolute carrier family 22 member 5transporter
IpratropiumSolute carrier family 22 member 4transporter
IpratropiumSerum albumincarrier
Ipratropiumalpha1-acid glycoproteincarrier
VinorelbineTubulin beta chaintarget
VinorelbineCytochrome P450 3A4enzyme
VinorelbineCytochrome P450 2D6enzyme
HyoscyamineMuscarinic acetylcholine receptor M1target
HyoscyamineMuscarinic acetylcholine receptor M2target
HyoscyamineMuscarinic acetylcholine receptor M3target
HyoscyamineMuscarinic acetylcholine receptor M4target
HyoscyamineAdenylate cyclase type 1target
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
OxycodoneMu-type opioid receptortarget
OxycodoneKappa-type opioid receptortarget
OxycodoneDelta-type opioid receptortarget
OxycodoneCytochrome P450 2D6enzyme
OxycodoneCytochrome P450 3A4enzyme
OxycodoneCytochrome P450 3A5enzyme
OxycodoneSerum albumincarrier
Oxycodonealpha1-acid glycoproteincarrier
DextromethorphanSigma non-opioid intracellular receptor 1target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DextromethorphanSodium-dependent serotonin transportertarget
DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DextromethorphanCytochrome P450 2D6enzyme
DextromethorphanCytochrome P450 3A4enzyme
DextromethorphanCytochrome P450 3A7enzyme
DextromethorphanCytochrome P450 2C9enzyme
DextromethorphanCytochrome P450 2B6enzyme
DextromethorphanCytochrome P450 2C19enzyme
DextromethorphanMembrane-associated progesterone receptor component 1target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DextromethorphanMu-type opioid receptortarget
DextromethorphanDelta-type opioid receptortarget
DextromethorphanKappa-type opioid receptortarget
DextromethorphanNADPH oxidasetarget
DextromethorphanSodium-dependent noradrenaline transportertarget
DextromethorphanUDP-glucuronosyltransferase 2B4enzyme
DextromethorphanUDP-glucuronosyltransferase 2B7enzyme
DextromethorphanUDP-glucuronosyltransferase 2B15enzyme
DextromethorphanUDP-glucuronosyltransferase 2B17enzyme
VincristineTubulin beta chaintarget
VincristineCytochrome P450 3A4enzyme
VincristineCytochrome P450 3A5enzyme
VincristineCytochrome P450 3A7enzyme
VincristineP-glycoprotein 1transporter
VincristineCanalicular multispecific organic anion transporter 2transporter
VincristineSolute carrier family 22 member 3transporter
VincristineMultidrug resistance-associated protein 1transporter
VincristineMultidrug resistance-associated protein 7transporter
VincristineCanalicular multispecific organic anion transporter 1transporter
VincristineBile salt export pumptransporter
VincristineATP-binding cassette sub-family G member 2transporter
VincristineTubulin alpha-4A chaintarget
VincristineRalA-binding protein 1transporter
VincristineSolute carrier organic anion transporter family member 1B1transporter
VincristineSolute carrier organic anion transporter family member 1B3transporter
VinblastineTubulin beta chaintarget
VinblastineTranscription factor AP-1target
VinblastineCytochrome P450 3A4enzyme
VinblastineP-glycoprotein 1transporter
VinblastineMultidrug resistance-associated protein 1transporter
VinblastineCanalicular multispecific organic anion transporter 1transporter
VinblastineMultidrug resistance-associated protein 6transporter
VinblastineBile salt export pumptransporter
VinblastineTubulin alpha-1A chaintarget
VinblastineTubulin delta chaintarget
VinblastineTubulin epsilon chaintarget
VinblastineTubulin gamma-1 chaintarget
VinblastineCytochrome P450 2D6enzyme
VinblastineSolute carrier organic anion transporter family member 1B1transporter
AtropineMuscarinic acetylcholine receptor M2target
AtropineMuscarinic acetylcholine receptor M1target
AtropineMuscarinic acetylcholine receptor M4target
AtropineMuscarinic acetylcholine receptor M5target
AtropineMuscarinic acetylcholine receptor M3target
AtropineGlycine receptor subunit alpha-1target
AtropineNeuronal acetylcholine receptor subunit alpha-4target
AtropineNeuronal acetylcholine receptor subunit beta-2target
AtropineBile salt export pumptransporter
AtropineAlpha-1-acid glycoprotein 1carrier
LisurideDopamine D1 receptortarget
Lisuride5-hydroxytryptamine receptor 1Atarget
LisurideDopamine D2 receptortarget
LisurideAlpha-2A adrenergic receptortarget
LisurideAlpha-2B adrenergic receptortarget
LisurideAlpha-2C adrenergic receptortarget
LisurideDopamine D3 receptortarget
Lisuride5-hydroxytryptamine receptor 1Dtarget
Lisuride5-hydroxytryptamine receptor 2Btarget
Lisuride5-hydroxytryptamine receptor 2Atarget
LisurideDopamine D4 receptortarget
Lisuride5-hydroxytryptamine receptor 2Ctarget
LisurideDopamine D5 receptortarget
Lisuride5-hydroxytryptamine receptor 1Btarget
LisurideCytochrome P450 3A4enzyme
Lisuride5-hydroxytryptamine receptor 7target
GalantamineAcetylcholinesterasetarget
GalantamineCytochrome P450 3A4enzyme
GalantamineCytochrome P450 2D6enzyme
GalantamineCholinesterasetarget
GalantamineP-glycoprotein 1transporter
GalantamineNeuronal acetylcholine receptor subunit alpha-7target
GalantamineMuscle nicotinic acetylcholine receptortarget
ApomorphineDopamine D2 receptortarget
ApomorphineDopamine D1 receptortarget
ApomorphineDopamine D4 receptortarget
ApomorphineDopamine D3 receptortarget
ApomorphineDopamine D5 receptortarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
ApomorphineCatechol O-methyltransferaseenzyme
ApomorphineSulfotransferase 1A1enzyme
ApomorphineSulfotransferase 1A2enzyme
ApomorphineSulfotransferase 1A3/1A4enzyme
ApomorphineEstrogen sulfotransferaseenzyme
ApomorphineSulfotransferase family cytosolic 1B member 1enzyme
ApomorphineCytochrome P450 2B6enzyme
ApomorphineCytochrome P450 2C8enzyme
ApomorphineCytochrome P450 3A4enzyme
ApomorphineCytochrome P450 3A5enzyme
ApomorphineUDP-glucuronosyltransferases (UGTs)enzyme
ApomorphineSerum albumincarrier
ApomorphineSynaptic vesicular amine transportertransporter
ScopolamineMuscarinic acetylcholine receptor M1target
ScopolamineSucrase-isomaltase, intestinaltarget
ScopolamineMuscarinic acetylcholine receptor M2target
ScopolamineMuscarinic acetylcholine receptor M3target
ScopolamineMuscarinic acetylcholine receptor M4target
ScopolamineMuscarinic acetylcholine receptor M5target
ScopolamineNeuronal acetylcholine receptor subunit alpha-4target
ScopolamineNeuronal acetylcholine receptor subunit beta-2target
ScopolamineCytochrome P450 3A4enzyme
IrinotecanDNA topoisomerase I, mitochondrialtarget
IrinotecanDNA topoisomerase 1target
IrinotecanCytochrome P450 3A4enzyme
IrinotecanCytochrome P450 3A5enzyme
IrinotecanUDP-glucuronosyltransferase 1-1enzyme
IrinotecanUDP-glucuronosyltransferase 1-9enzyme
IrinotecanLiver carboxylesterase 1enzyme
IrinotecanCytochrome P450 3A7enzyme
IrinotecanCytochrome P450 2B6enzyme
IrinotecanSolute carrier family 22 member 3transporter
IrinotecanSolute carrier organic anion transporter family member 1B1transporter
IrinotecanMultidrug resistance-associated protein 1transporter
IrinotecanATP-binding cassette sub-family G member 2transporter
IrinotecanSerum albumincarrier
IrinotecanCocaine esteraseenzyme
IrinotecanCholinesteraseenzyme
IrinotecanP-glycoprotein 1transporter
IrinotecanCanalicular multispecific organic anion transporter 1transporter
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
CocaineSodium-dependent noradrenaline transportertarget
CocaineSodium channel proteintarget
CocaineSodium-dependent serotonin transportertarget
CocaineSodium-dependent dopamine transportertarget
CocaineCytochrome P450 3A4enzyme
CocaineMuscarinic acetylcholine receptor M1target
CocaineMuscarinic acetylcholine receptor M2target
CocaineCytochrome P450 2D6enzyme
CocaineSolute carrier family 22 member 2transporter
CocaineCytochrome P450 2C8enzyme
CocaineSigma non-opioid intracellular receptor 1target
CocaineLiver carboxylesterase 1target
CocaineCholinesteraseenzyme
CocaineSodium-dependent dopamine transportertransporter
Cocainealpha1-acid glycoproteincarrier
CocaineLiver carboxylesterase 1enzyme
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
QuinidineSerum albumincarrier
HydrocodoneMu-type opioid receptortarget
HydrocodoneDelta-type opioid receptortarget
HydrocodoneCytochrome P450 3A4enzyme
HydrocodoneCytochrome P450 2D6enzyme
HydrocodoneCytochrome P450 2B6enzyme
HydrocodoneCytochrome P450 2C19enzyme
HydrocodoneSigma non-opioid intracellular receptor 1target
DimenhydrinateHistamine H1 receptortarget
TopotecanDNA topoisomerase I, mitochondrialtarget
TopotecanDNA topoisomerase 1target
TopotecanATP-binding cassette sub-family G member 2transporter
TopotecanP-glycoprotein 1transporter
TopotecanDNAtarget
TopotecanMultidrug and toxin extrusion protein 1transporter
TopotecanMultidrug and toxin extrusion protein 2transporter
PilocarpineMuscarinic acetylcholine receptor M1target
PilocarpineMuscarinic acetylcholine receptor M2target
PilocarpineCytochrome P450 2A6enzyme
PilocarpineMuscarinic acetylcholine receptor M3target
PilocarpineCytochrome P450 3A4enzyme
PilocarpineMuscarinic acetylcholine receptor M4target
PilocarpineMuscarinic acetylcholine receptor M5target
PilocarpineSerum paraoxonase/arylesterase 1enzyme
PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
PapaverinePhosphodiesterase enzymestarget
NaloxoneMu-type opioid receptortarget
NaloxoneEstrogen receptor alphatarget
NaloxoneCyclic AMP-responsive element-binding protein 1target
NaloxoneDelta-type opioid receptortarget
NaloxoneSolute carrier organic anion transporter family member 1A2transporter
NaloxoneP-glycoprotein 1transporter
NaloxoneKappa-type opioid receptortarget
NaloxoneCytochrome P450 3A4enzyme
NaloxoneSerum albumincarrier
NaloxoneToll-like receptor 4target
NaloxoneLiver carboxylesterase 1target
NaloxoneUDP-glucuronosyltransferase 1-1enzyme
NaloxoneCytochrome P450 2C18enzyme
NaloxoneCytochrome P450 2C19enzyme
PergolideDopamine D2 receptortarget
PergolideDopamine D1 receptortarget
PergolideDopamine D3 receptortarget
Pergolide5-hydroxytryptamine receptor 1Atarget
PergolideAlpha-1A adrenergic receptortarget
PergolideAlpha-2 adrenergic receptorstarget
PergolideAlpha-1B adrenergic receptortarget
PergolideAlpha-1D adrenergic receptortarget
PergolideDopamine D4 receptortarget
PergolideDopamine D5 receptortarget
Pergolide5-hydroxytryptamine receptor 1Btarget
Pergolide5-hydroxytryptamine receptor 1Dtarget
Pergolide5-hydroxytryptamine receptor 2Atarget
Pergolide5-hydroxytryptamine receptor 2Btarget
Pergolide5-hydroxytryptamine receptor 2Ctarget
PergolideCytochrome P450 3A4enzyme
TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
TubocurarineAcetylcholinesterasetarget
Tubocurarine5-hydroxytryptamine receptor 3Atarget
TubocurarineSolute carrier family 22 member 1transporter
TubocurarineSolute carrier family 22 member 2transporter
TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
TubocurarineCholinesteraseenzyme
ColchicineTubulin beta chaintarget
ColchicineCytochrome P450 3A4enzyme
ColchicineP-glycoprotein 1transporter
ColchicineCytochrome P450 2B6enzyme
ColchicineCytochrome P450 2C8enzyme
ColchicineCytochrome P450 2E1enzyme
ColchicineSerum albumincarrier
TiotropiumMuscarinic acetylcholine receptor M3target
TiotropiumCytochrome P450 2D6enzyme
TiotropiumCytochrome P450 3A4enzyme
TiotropiumMuscarinic acetylcholine receptor M1target
TiotropiumMuscarinic acetylcholine receptor M2target
TiotropiumSolute carrier family 22 member 5transporter
TiotropiumSolute carrier family 22 member 4transporter
TiotropiumMuscarinic acetylcholine receptor M4target
TiotropiumMuscarinic acetylcholine receptor M5target
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
ArecolineMuscarinic acetylcholine receptor M1target
ArecolineMuscarinic acetylcholine receptor M3target
CamptothecinDNA topoisomerase 1target
CamptothecinP-glycoprotein 1transporter
CamptothecinATP-binding cassette sub-family G member 2transporter
CamptothecinSerum albumincarrier
Omacetaxine mepesuccinate50S ribosomal protein L2target
Omacetaxine mepesuccinate60S ribosomal protein L3target
NoscapineSigma non-opioid intracellular receptor 1target
NoscapineCytochrome P450 2C9enzyme
NoscapineCytochrome P450 3A4enzyme
SparteineCytochrome P450 2D6enzyme
DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DrotaverineVoltage-dependent L-type calcium channeltarget
HomatropineLiver carboxylesterase 1enzyme
HomatropineMuscarinic acetylcholine receptor M1target
HomatropineMuscarinic acetylcholine receptor M2target
HomatropineMuscarinic acetylcholine receptor M3target
HomatropineMuscarinic acetylcholine receptor M4target
HomatropineMuscarinic acetylcholine receptor M5target
VinflunineATP-binding cassette sub-family B member 5transporter
VinflunineP-glycoprotein 1transporter
VinflunineSerum albumincarrier
Vinfluninealpha1-acid glycoproteincarrier
VinflunineCytochrome P450 3A4enzyme
VinflunineTubulin beta chaintarget
SamidorphanMu-type opioid receptortarget
SamidorphanKappa-type opioid receptortarget
SamidorphanDelta-type opioid receptortarget
SamidorphanCytochrome P450 3A4enzyme
SamidorphanCytochrome P450 3A5enzyme
SamidorphanCytochrome P450 2C19enzyme
SamidorphanCytochrome P450 2C8enzyme
Sacituzumab govitecanTumor-associated calcium signal transducer 2target
Sacituzumab govitecanDNA topoisomerase 1target
Sacituzumab govitecanFar upstream element-binding protein 1target
Sacituzumab govitecanUDP-glucuronosyltransferase 1-1enzyme
ColchiceineTubulin beta chaintarget
ColchiceineTubulin alpha-1A chaintarget
ColchiceineSerum albumincarrier
Variolin BCyclin-dependent kinase 2target
Variolin BCyclin-A2target
1-deoxymannojirimycinAlpha-mannosidase 2target
AjmalineAlpha-1-acid glycoprotein 1carrier
AjmalineSodium channel protein type 5 subunit alphatarget
K-252aHepatocyte growth factor receptortarget
K-252aDual specificity mitogen-activated protein kinase kinase 1target
LobelineNeuronal acetylcholine receptor subunit alpha-9target
LobelineNeuronal acetylcholine receptor subunit alpha-10target
LobelineNeuronal acetylcholine receptor subunit alpha-7target
Rauwolfia serpentina rootSynaptic vesicular amine transportertarget
Rauwolfia serpentina rootMonoamine oxidaseenzyme
Rauwolfia serpentina rootSodium-dependent noradrenaline transportertransporter
Rauwolfia serpentina rootvesicular monoamine transporter 2 (VMAT2)transporter
TetrandrineP-glycoprotein 1target
TetrandrineCytochrome P450 3A4enzyme
TetrandrineP-glycoprotein 1transporter
NicotineNeuronal acetylcholine receptor subunit alpha-2target
NicotineNeuronal acetylcholine receptor subunit beta-2target
NicotineNeuronal acetylcholine receptor subunit alpha-7target
NicotineNeuronal acetylcholine receptor subunit alpha-4target
NicotineNeuronal acetylcholine receptor subunit alpha-10target
NicotineNeuronal acetylcholine receptor subunit alpha-9target
NicotineCytochrome P450 2A6enzyme
NicotineCytochrome P450 2E1enzyme
NicotineCytochrome P450 2A13enzyme
NicotineCytochrome P450 2B6enzyme
NicotineNeuronal acetylcholine receptor subunit beta-4target
NicotineNeuronal acetylcholine receptor subunit alpha-3target
NicotineNeuronal acetylcholine receptor subunit alpha-5target
NicotineNeuronal acetylcholine receptor subunit alpha-6target
NicotineNeuronal acetylcholine receptor subunit beta-3target
NicotineSolute carrier family 22 member 2transporter
NicotineSolute carrier family 22 member 1transporter
NicotineSolute carrier family 22 member 3transporter
NicotineSolute carrier family 22 member 5transporter
NicotineSolute carrier family 22 member 4transporter
NicotineCytochrome P450 1A1enzyme
NicotineCytochrome P450 1A2enzyme
NicotineCytochrome P450 2C19enzyme
NicotineCytochrome P450 2C8enzyme
NicotineCytochrome P450 2C9enzyme
NicotineCytochrome P450 2D6enzyme
NicotineCytochrome P450 3A4enzyme
NicotineAmine oxidase [flavin-containing] Aenzyme
NicotineAmine oxidase [flavin-containing] Benzyme
NicotineCytochrome P450 19A1target
NicotineCholine O-acetyltransferasetarget
Methysergide5-hydroxytryptamine receptor 2Atarget
Methysergide5-hydroxytryptamine receptor 1Atarget
Methysergide5-hydroxytryptamine receptor 7target
Methysergide5-hydroxytryptamine receptor 2Ctarget
Methysergide5-hydroxytryptamine receptor 2Btarget
Methysergide5-hydroxytryptamine receptor 1Btarget
Methysergide5-hydroxytryptamine receptor 1Ftarget
Methysergide5-hydroxytryptamine receptor 1Etarget
MethysergideCytochrome P450 3A4enzyme
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
MethylergometrineDopamine D1 receptortarget
MethylergometrineCytochrome P450 3A4enzyme
Methylergometrine5-hydroxytryptamine receptor 2Btarget
Metocurine iodideNeuronal acetylcholine receptor subunit alpha-2target
MiglustatCeramide glucosyltransferasetarget
Methscopolamine bromideMuscarinic acetylcholine receptor M1target
Methscopolamine bromideMuscarinic acetylcholine receptor M2target
Methscopolamine bromideMuscarinic acetylcholine receptor M3target
MiglitolMaltase-glucoamylase, intestinaltarget
MiglitolPancreatic alpha-amylaseenzyme
MiglitolLysosomal alpha-glucosidasetarget
MiglitolNeutral alpha-glucosidase ABtarget
MiglitolNeutral alpha-glucosidase Ctarget
LevallorphanMu-type opioid receptortarget
Anisotropine methylbromideMuscarinic acetylcholine receptor M1target
Anisotropine methylbromideMuscarinic acetylcholine receptor M2target
Anisotropine methylbromideMuscarinic acetylcholine receptor M3target
ButorphanolKappa-type opioid receptortarget
ButorphanolMu-type opioid receptortarget
ButorphanolDelta-type opioid receptortarget
PentazocineMu-type opioid receptortarget
PentazocineKappa-type opioid receptortarget
PentazocineSigma non-opioid intracellular receptor 1target
PentazocineP-glycoprotein 1transporter
ErgotamineAlpha-1A adrenergic receptortarget
Ergotamine5-hydroxytryptamine receptor 1Dtarget
Ergotamine5-hydroxytryptamine receptor 1Btarget
Ergotamine5-hydroxytryptamine receptor 2Atarget
ErgotamineAlpha-2A adrenergic receptortarget
ErgotamineDopamine D2 receptortarget
ErgotamineCytochrome P450 3A4enzyme
ErgotamineAlpha-1B adrenergic receptortarget
ErgotamineAlpha-1D adrenergic receptortarget
ErgotamineP-glycoprotein 1transporter
ErgotamineD(1) dopamine receptortarget
Ergotamine5-hydroxytryptamine receptor 1Atarget
Ergotamine5-hydroxytryptamine receptor 1Ftarget
Ergotamine5-hydroxytryptamine receptor 2Ctarget
Ergotamine5-hydroxytryptamine receptor 2Btarget
ErgotamineAlpha-2C adrenergic receptortarget
NicergolineAlpha-1A adrenergic receptortarget
NicergolineCytochrome P450 2D6enzyme
NaltrexoneMu-type opioid receptortarget
NaltrexoneKappa-type opioid receptortarget
NaltrexoneDelta-type opioid receptortarget
NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
NaltrexoneSigma non-opioid intracellular receptor 1target
Homatropine methylbromideMuscarinic acetylcholine receptor M2target
Homatropine methylbromideMuscarinic acetylcholine receptor M1target
Homatropine methylbromideMuscarinic acetylcholine receptor M4target
Homatropine methylbromideMuscarinic acetylcholine receptor M5target
Homatropine methylbromideMuscarinic acetylcholine receptor M3target
CryptenamineMuscarinic acetylcholine receptor M2target
CryptenamineBeta adrenergic receptortarget
EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
EnprofyllineAdenosine receptor A2btarget
EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
EnprofyllineAdenosine receptor A1target
EnprofyllineAdenosine receptor A2atarget
EnprofyllineAdenosine receptor A3target
NalbuphineKappa-type opioid receptortarget
NalbuphineMu-type opioid receptortarget
NalbuphineDelta-type opioid receptortarget
LevorphanolMu-type opioid receptortarget
LevorphanolDelta-type opioid receptortarget
LevorphanolKappa-type opioid receptortarget
BuprenorphineKappa-type opioid receptortarget
BuprenorphineMu-type opioid receptortarget
BuprenorphineCytochrome P450 3A4enzyme
BuprenorphineCytochrome P450 2D6enzyme
BuprenorphineP-glycoprotein 1transporter
BuprenorphineATP-binding cassette sub-family G member 2transporter
BuprenorphineCytochrome P450 2C9enzyme
BuprenorphineCytochrome P450 3A5enzyme
BuprenorphineCytochrome P450 2C8enzyme
BuprenorphineCytochrome P450 3A7enzyme
BuprenorphineDelta-type opioid receptortarget
BuprenorphineCytochrome P450 2C18enzyme
BuprenorphineCytochrome P450 2C19enzyme
BuprenorphineNociceptin receptortarget
PhysostigmineAcetylcholinesterasetarget
PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
Ergoloid mesylateDopamine receptortarget
Ergoloid mesylateAlpha adrenergic receptortarget
Ergoloid mesylateBeta adrenergic receptortarget
Ergoloid mesylateSerotonin Receptorstarget
Ergoloid mesylateCytochrome P450 3A4enzyme
DeserpidineSynaptic vesicular amine transportertarget
RescinnamineAngiotensin-converting enzymetarget
OxymorphoneMu-type opioid receptortarget
OxymorphoneCytochrome P450 2D6enzyme
OxymorphoneDelta-type opioid receptortarget
OxymorphoneCytochrome P450 3A4enzyme
BromocriptineDopamine D2 receptortarget
BromocriptineCytochrome P450 3A4enzyme
Bromocriptine5-hydroxytryptamine receptor 1Dtarget
BromocriptineAlpha-2A adrenergic receptortarget
BromocriptineDopamine D3 receptortarget
Bromocriptine5-hydroxytryptamine receptor 1Atarget
BromocriptineAlpha-2C adrenergic receptortarget
BromocriptineAlpha-2B adrenergic receptortarget
Bromocriptine5-hydroxytryptamine receptor 2Btarget
BromocriptineDopamine D4 receptortarget
Bromocriptine5-hydroxytryptamine receptor 2Atarget
Bromocriptine5-hydroxytryptamine receptor 1Btarget
Bromocriptine5-hydroxytryptamine receptor 2Ctarget
BromocriptineDopamine D5 receptortarget
BromocriptineDopamine D1 receptortarget
BromocriptineAlpha-1A adrenergic receptortarget
BromocriptineAlpha-1B adrenergic receptortarget
BromocriptineAlpha-1D adrenergic receptortarget
Bromocriptine5-hydroxytryptamine receptor 7target
BromocriptineP-glycoprotein 1transporter
ErgometrineCytochrome P450 3A4enzyme
ErgometrineP-glycoprotein 1transporter
ErgometrineAlpha-1A adrenergic receptortarget
OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
OxtriphyllineAdenosine receptor A2atarget
OxtriphyllineAdenosine receptor A1target
OxtriphyllineCytochrome P450 1A2enzyme
OxtriphyllineSolute carrier family 22 member 7transporter
OxtriphyllineHistone deacetylase 2target
MetocurineNeuronal acetylcholine receptor subunit alpha-2target
MetocurineMuscarinic acetylcholine receptor M2target
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
AlmitrineSodium/potassium-transporting ATPase subunit alpha-1target
DiamorphineMu-type opioid receptortarget
DiamorphineKappa-type opioid receptortarget
DiamorphineDelta-type opioid receptortarget
DiamorphineLiver carboxylesterase 1target
DiamorphineThyroxine-binding globulincarrier
EthylmorphineCytochrome P450 2D6enzyme
EthylmorphineNADPH--cytochrome P450 reductaseenzyme
EthylmorphineMu-type opioid receptortarget
EthylmorphineCytochrome P450 2B6enzyme
EthylmorphineCytochrome P450 3A4enzyme
FenethyllineCytochrome P450 1A2enzyme
EtorphineE3 ubiquitin-protein ligase TRIM13target
EtorphinePro-opiomelanocortintarget
EtorphineMu-type opioid receptortarget
EtorphineDelta-type opioid receptortarget
EtorphineKappa-type opioid receptortarget
EtorphineNociceptin receptortarget
DiprenorphineE3 ubiquitin-protein ligase TRIM13target
DiprenorphineDelta-type opioid receptortarget
DiprenorphineKappa-type opioid receptortarget
DiprenorphineMu-type opioid receptortarget
DihydrocodeineCytochrome P450 2D6enzyme
DihydrocodeineCytochrome P450 3A4enzyme
DihydromorphineE3 ubiquitin-protein ligase TRIM13target
DihydromorphinePro-opiomelanocortintarget
DihydromorphineMu-type opioid receptortarget
DihydromorphineDelta-type opioid receptortarget
DihydromorphineKappa-type opioid receptortarget
8-azaxanthineUric acid degradation bifunctional proteintarget
7-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
StaurosporineTyrosine-protein kinase Lcktarget
StaurosporineSerine/threonine-protein kinase pim-1target
StaurosporineTyrosine-protein kinase ITK/TSKtarget
StaurosporineTyrosine-protein kinase SYKtarget
StaurosporineMAP kinase-activated protein kinase 2target
StaurosporineGlycogen synthase kinase-3 betatarget
StaurosporineTyrosine-protein kinase CSKtarget
StaurosporineCyclin-dependent kinase 2target
StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
Staurosporine3-phosphoinositide-dependent protein kinase 1target
StaurosporineProtein kinase C theta typetarget
StaurosporineTyrosine-protein kinase ZAP-70target
StaurosporineP-glycoprotein 1transporter
StaurosporineMuscarinic acetylcholine receptor M1target
StaurosporineProtein kinase Ctarget
XanthinePurine nucleoside phosphorylase 2target
XanthineXanthine phosphoribosyltransferasetarget
XanthineCytochrome P450 1A2enzyme
DeacetoxyvinzolidineCalmodulintarget
BerberineHTH-type transcriptional regulator QacRtarget
BerberineBaculoviral IAP repeat-containing protein 5target
Calystegine B2Beta-glucosidase Atarget
MethylecgonineIg gamma-2 chain C regiontarget
MethylecgonineIg kappa chain C regiontarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 1Atarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 2Btarget
Lysergic acid diethylamide5-hydroxytryptamine receptor 6target
Lysergic acid diethylamideCytochrome P450 3A4enzyme
Lysergic acid diethylamideCytochrome P450 2D6enzyme
VoacamineP-glycoprotein 1target
VoacamineP-glycoprotein 1transporter
PhenserineAcetylcholinesterasetarget
PhenserineCholinesterasetarget
PhenserineAmyloid beta A4 proteintarget
AltropaneSodium-dependent dopamine transportertarget
MigalastatAlpha-galactosidase Atarget
MigalastatSodium/glucose cotransporter 1transporter
VintafolideFolate receptor betatarget
VintafolideFolate receptor gammatarget
VintafolideFolate receptor alphatarget
SN-38DNA topoisomerase 1target
SN-38Cytochrome P450 3A4enzyme
CositecanDNA topoisomerase 1target
RivaniclineNeuronal acetylcholine receptor subunit beta-2target
RivaniclineInterleukin-8target
XMT-1001DNA topoisomerase 1target
RubitecanDNA topoisomerase 1target
NalmefeneMu-type opioid receptortarget
NalmefeneKappa-type opioid receptortarget
NalmefeneDelta-type opioid receptortarget
NalmefeneUDP-glucuronosyltransferase 2B7enzyme
NalmefeneUDP-glucuronosyltransferase 1-3enzyme
NalmefeneUDP-glucuronosyltransferase 1-8enzyme
NalmefeneCytochrome P450 3A4enzyme
NalmefeneCytochrome P450 3A5enzyme
Morphine glucuronideMu-type opioid receptortarget
Morphine glucuronideDelta-type opioid receptortarget
Morphine glucuronideKappa-type opioid receptortarget
NaxifyllineAdenosine receptor A1target
PropentofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PropentofyllineCytochrome P450 1A2enzyme
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
GimatecanSolute carrier organic anion transporter family member 1B1transporter
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
MethylnaltrexoneMu-type opioid receptortarget
MethylnaltrexoneKappa-type opioid receptortarget
HarmineAmine oxidase [flavin-containing] Atarget
Ioflupane I-123Sodium-dependent dopamine transportertransporter
Uric acidSolute carrier family 22 member 6transporter
Uric acidSolute carrier family 22 member 8transporter
Uric acidGlycogen phosphorylase, liver formtarget
Uric acidSolute carrier family 2, facilitated glucose transporter member 9transporter
AclidiniumMuscarinic acetylcholine receptor M1target
AclidiniumMuscarinic acetylcholine receptor M2target
AclidiniumMuscarinic acetylcholine receptor M3target
AclidiniumMuscarinic acetylcholine receptor M4target
AclidiniumMuscarinic acetylcholine receptor M5target
AclidiniumCholinesteraseenzyme
NaloxegolCytochrome P450 3A4enzyme
NaloxegolCytochrome P450 2D6enzyme
NaloxegolCytochrome P450 2C19enzyme
NaloxegolMu-type opioid receptortarget
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
PholcodineMu-type opioid receptortarget
PholcodineKappa-type opioid receptortarget
PholcodineDelta-type opioid receptortarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
DoxofyllinecGMP-dependent 3',5'-cyclic phosphodiesterasetarget
ButylscopolamineMuscarinic acetylcholine receptor M3target
ButylscopolamineMuscarinic acetylcholine receptor M2target
DihydroergocornineSerotonin Receptorstarget
DihydroergocornineBeta adrenergic receptortarget
DihydroergocornineAlpha adrenergic receptortarget
DihydroergocornineCytochrome P450 3A4enzyme
EpicriptineDopamine receptortarget
NonivamideTransient receptor potential cation channel subfamily V member 1target
ThiocolchicosideGABA(A) Receptortarget
ThiocolchicosideGlycine receptor subunit alpha-1target
ThiocolchicosideTumor necrosis factor ligand superfamily member 11target
NaldemedineCytochrome P450 3A Subfamilyenzyme
NaldemedineUDP-glucuronosyltransferase 1-3enzyme
NaldemedineMu-type opioid receptortarget
NaldemedineDelta-type opioid receptortarget
NaldemedineKappa-type opioid receptortarget
NaldemedineATP-binding cassette sub-family B member 5transporter
AnisodamineCytochrome P450 2D6enzyme
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
VinpocetineCytochrome P450 3A4enzyme
9-aminocamptothecinCytochrome P450 3A4enzyme
TonapofyllineAdenosine receptor A1target
RolofyllineAdenosine receptor A1target
Ambroxol acefyllinateCytochrome P450 3A Subfamilyenzyme
BamifyllineCytochrome P450 1A2enzyme
DihydroergocristineSerotonin Receptorstarget
DihydroergocristineBeta adrenergic receptortarget
DihydroergocristineAlpha adrenergic receptortarget
DihydroergocristineDopamine receptortarget
DihydroergocristineBile salt export pumptransporter
DihydroergocristineCytochrome P450 3A4enzyme
DihydroergocryptineCytochrome P450 3A4enzyme
TergurideCytochrome P450 3A4enzyme
ProxyphyllineCytochrome P450 1A2enzyme
MetergolineSodium channel protein type 2 subunit alphatarget
AcefyllineCytochrome P450 1A2enzyme
EtamiphyllineCytochrome P450 1A2enzyme
PentifyllineCytochrome P450 1A2enzyme
BufyllineCytochrome P450 1A2enzyme
HarmalineHistamine N-methyltransferasetarget
BromotheophyllineCytochrome P450 1A2enzyme
FurafyllineCytochrome P450 1A2enzyme
8-chlorotheophyllineAdenosine receptor A2atarget
8-chlorotheophyllineCytochrome P450 1A2enzyme
LoxicodegolMu-type opioid receptortarget
LoxicodegolDelta-type opioid receptortarget
LoxicodegolKappa-type opioid receptortarget
LoxicodegolP-glycoprotein 1transporter
Gibberellic acidArylacetamide deacetylase-like 2target
Gibberellin A4Arylacetamide deacetylase-like 2target
CytisineNeuronal acetylcholine receptor subunit alpha-4target
CytisineNeuronal acetylcholine receptor subunit alpha-7target
CytisineNeuronal acetylcholine receptor subunit alpha-3target
CytisineNeuronal acetylcholine receptor subunit alpha-6target
CytisineNeuronal acetylcholine receptor subunit beta-2target