Pyrimidine Nucleotides

Name
Pyrimidine Nucleotides
Accession Number
DBCAT000913
Description

Pyrimidines with a RIBOSE and phosphate attached that can polymerize to form DNA and RNA.

Drugs
DrugDrug Description
ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
Thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Uridine diphosphate glucoseA key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and...
Cytidine 3'-monophosphateNot Available
5-methylcytidine 5'-monophosphateNot Available
Thymidine 5'-triphosphateNot Available
3'-UridinemonophosphateNot Available
Stavudine triphosphateNot Available
Orotidylic acidNot Available
UDP-alpha-D-glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides....
2'-Deoxycytidine 5'-triphosphateNot Available
Deoxycytidylyl-3',5'-guanosineNot Available
Cytidine-5'-MonophosphateA pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Galactose-uridine-5'-diphosphateA nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides,...
Zidovudine monophosphateNot Available
Uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
6-aza uridine 5'-monophosphateNot Available
2'-Deoxy-thymidine-beta-L-rhamnoseNot Available
5-fluoro-2'-deoxyuridine-5'-monophosphateNot Available
2'-cytidylic acidNot Available
Deoxyuridine monophosphateNot Available
Uridine 5'-triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
TMPNot Available
Zidovudine diphosphateNot Available
Cyclic 3',5'-thymidine monophosphateNot Available
DenufosolFor use as an inhaled treatment for cystic fibrosis.
SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
CiticolineAn endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.
osgemcitabine palabenamideNUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
DiquafosolA medication indicated to treat dry eyes associated with keratoconjunctival disorders.
Drugs & Drug Targets
DrugTargetType
ChlordiazepoxideGABA(A) Receptortarget
ChlordiazepoxideGABA(A) Receptor Benzodiazepine Binding Sitetarget
ChlordiazepoxideCytochrome P450 3A4enzyme
Thymidine monophosphateThymidylate kinasetarget
Thymidine monophosphateThymidylate kinasetarget
Thymidine monophosphateThymidylate synthasetarget
Thymidine monophosphateDNA topoisomerase 1target
Thymidine monophosphateThymidylate synthasetarget
Thymidine monophosphatePCZA361.16target
Thymidine monophosphateDNA polymerase III subunit epsilontarget
Thymidine monophosphateGlucose-1-phosphate thymidylyltransferasetarget
Uridine diphosphate glucoseGalactose-1-phosphate uridylyltransferasetarget
Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
Uridine diphosphate glucoseAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
Uridine diphosphate glucoseGlucose-1-phosphate thymidylyltransferasetarget
Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
Uridine diphosphate glucoseDNA beta-glucosyltransferasetarget
Uridine diphosphate glucoseGlycosyltransferase 6 domain-containing protein 1target
Uridine diphosphate glucoseWbpPtarget
Uridine diphosphate glucoseGlycogenin-1target
Uridine diphosphate glucoseUracil nucleotide/cysteinyl leukotriene receptortarget
Cytidine 3'-monophosphateRibonuclease pancreatictarget
Thymidine 5'-triphosphateThymidine kinase, cytosolictarget
Thymidine 5'-triphosphateAnaerobic ribonucleoside-triphosphate reductasetarget
Thymidine 5'-triphosphateThymidylate kinasetarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferase 2target
Thymidine 5'-triphosphateDNA primase/helicasetarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferasetarget
Thymidine 5'-triphosphateThymidine kinase 2, mitochondrialtarget
Thymidine 5'-triphosphateThymidine kinasetarget
Thymidine 5'-triphosphateRibonucleoside-diphosphate reductase 2 subunit alphatarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferasetarget
3'-UridinemonophosphateRibonuclease pancreatictarget
Stavudine triphosphateNucleoside diphosphate kinase Atarget
UDP-alpha-D-glucuronic acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3target
UDP-alpha-D-glucuronic acidUDP-glucose 6-dehydrogenasetarget
UDP-alpha-D-glucuronic acidUDP-glucose 4-epimerasetarget
2'-Deoxycytidine 5'-triphosphateAnaerobic ribonucleoside-triphosphate reductasetarget
2'-Deoxycytidine 5'-triphosphateDeoxycytidine triphosphate deaminasetarget
2'-Deoxycytidine 5'-triphosphateDNA polymerase I, thermostabletarget
2'-Deoxycytidine 5'-triphosphateRibonucleoside-diphosphate reductase 2 subunit alphatarget
Deoxycytidylyl-3',5'-guanosineRibonuclease pancreatictarget
Cytidine-5'-MonophosphateUridine-cytidine kinase 2target
Cytidine-5'-Monophosphate3-deoxy-manno-octulosonate cytidylyltransferasetarget
Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
Cytidine-5'-MonophosphateBifunctional enzyme IspD/IspFtarget
Cytidine-5'-MonophosphateUMP-CMP kinasetarget
Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
Cytidine-5'-MonophosphateCytidylate kinasetarget
Cytidine-5'-MonophosphateCoenzyme A biosynthesis bifunctional protein CoaBCtarget
Cytidine-5'-MonophosphateAlpha-2,3-/2,8-sialyltransferasetarget
Galactose-uridine-5'-diphosphateHisto-blood group ABO system transferasetarget
Galactose-uridine-5'-diphosphateUDP-glucose 4-epimerasetarget
Galactose-uridine-5'-diphosphateBeta-1,4-galactosyltransferase 1target
Galactose-uridine-5'-diphosphateUracil nucleotide/cysteinyl leukotriene receptortarget
Zidovudine monophosphateThymidylate kinasetarget
Zidovudine monophosphateThymidylate kinasetarget
Uridine monophosphateUridine-cytidine kinase-like 1target
Uridine monophosphateGalactose-1-phosphate uridylyltransferasetarget
Uridine monophosphateThymidylate synthasetarget
Uridine monophosphateGlycosyltransferase 6 domain-containing protein 1target
Uridine monophosphateU6 snRNA-associated Sm-like protein LSm6target
Uridine monophosphateUracil phosphoribosyltransferasetarget
Uridine monophosphateBeta-1,4-galactosyltransferase 1target
Uridine monophosphateInterferon-stimulated gene 20 kDa proteintarget
Uridine monophosphateOrotidine 5'-phosphate decarboxylasetarget
Uridine monophosphateBifunctional protein PyrRtarget
Uridine monophosphateUracil phosphoribosyltransferasetarget
Uridine monophosphateBifunctional polymyxin resistance protein ArnAtarget
Uridine monophosphateRibosomal small subunit pseudouridine synthase Atarget
2'-Deoxy-thymidine-beta-L-rhamnosedTDP-4-dehydrorhamnose reductasetarget
2'-Deoxy-thymidine-beta-L-rhamnoseGlucose-1-phosphate thymidylyltransferasetarget
5-fluoro-2'-deoxyuridine-5'-monophosphateThymidylate synthasetarget
5-fluoro-2'-deoxyuridine-5'-monophosphateThymidylate synthasetarget
5-fluoro-2'-deoxyuridine-5'-monophosphateThymidylate synthase ThyXtarget
5-fluoro-2'-deoxyuridine-5'-monophosphateThymidylate synthase 1target
2'-cytidylic acidRibonuclease pancreatictarget
Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthase ThyXtarget
Deoxyuridine monophosphatePol polyproteintarget
Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Uridine 5'-triphosphateUridine-cytidine kinase 2target
Uridine 5'-triphosphateGenome polyproteintarget
Uridine 5'-triphosphateGenome polyproteintarget
TMPSingle-stranded DNA-binding proteintarget
Zidovudine diphosphateNucleoside diphosphate kinase Atarget
Cyclic 3',5'-thymidine monophosphate5'(3')-deoxyribonucleotidase, mitochondrialtarget
DenufosolP2Y purinoceptor 2target
SofosbuvirP-glycoprotein 1transporter
SofosbuvirATP-binding cassette sub-family G member 2transporter
SofosbuvirRNA-dependent RNA-polymerasetarget
SofosbuvirLysosomal protective proteinenzyme
SofosbuvirCarboxylesteraseenzyme
SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
SofosbuvirUMP-CMP kinaseenzyme
SofosbuvirNucleoside diphosphate kinase Aenzyme
CiticolineLicC proteintarget