Glucosidases

Name
Glucosidases
Accession Number
DBCAT001323
Description

Enzymes that hydrolyze O-glucosyl-compounds. (Enzyme Nomenclature, 1992) EC 3.2.1.-.

Drugs
DrugDrug Description
Alglucosidase alfaAn acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency.
ImigluceraseA form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
AlgluceraseA form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
Taliglucerase alfaA hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease.
Drugs & Drug Targets
DrugTargetType
Alglucosidase alfaCation-dependent mannose-6-phosphate receptortarget
Alglucosidase alfaGlycogentarget
ImigluceraseGlucocerebrosidetarget
AlgluceraseGlucocerebrosidetarget
Taliglucerase alfaGlucocerebrosidetarget