Transition Elements

Name
Transition Elements
Accession Number
DBCAT001388
Description

Elements with partially filled d orbitals. They constitute groups 3-12 of the periodic table of elements.

Drugs
DrugDrug Description
IronAn essential element commonly used for the treatment of patients with documented iron deficiency.
ZincAn essential element commonly used for the treatment of patients with documented zinc deficiency.
ManganeseA transition metal used for supplementation of manganese during Total Parenteral Nutrition (TPN).
ChromiumAn ingredient found in a variety of supplements and vitamins.
MolybdenumAn ingredient found in a variety of supplements and vitamins.
GoldA yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental...
Technetium Tc-99mA radiopharmaceutical indicated in imaging tests.
CopperA transition metal found in a variety of supplements and vitamins, including intravenous solutions for total parenteral nutrition (TPN).
PlatinumPlatinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine...
TantalumTantalum has been investigated for the treatment and prevention of Osteoarthritis, Knee Osteoarthritis, Intraoperative Bleeding, and Adolescent Idiopathic Scoliosis.
SilverIndicated for the treatment of acne for topical use or the management of dental caries for dental use.
NiobiumNiobium has been used in trials studying the treatment of Obesity and Overweight.
VanadiumA micronutrient used in some multivitamins and parenteral nutrition.
CadmiumAn element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
TitaniumNot Annotated
CobaltA metal element used in various nutritional products.
M40403Intended for the treatment of pain and possibly various forms of cancer.
TetrathiomolybdateInvestigated for use/treatment in liver disease and pulmonary fibrosis.
Cupric ChlorideA transition metal found in a variety of supplements and vitamins, including intravenous solutions for total parenteral nutrition (TPN).
Ferric pyrophosphateFerric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.[L1423, L1433] Iron deficiency appears when the...
Titanium dioxideA sunscreen agent found in sunscreens that absorbs UV rays.
Ammonium molybdateAmmonium molybdate is a source of molybdenum that exists in several hydrate forms. It is intravenously administered as an additive to solutions for Total Parenteral Nutrition (TPN). Molybdenum is an...
Cupric oxideAn ingredient found in a variety of supplements and vitamins.
Chromium Cr-51Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular...
PerflubutanePerflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable...
Yttrium Y-90Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer.
Gold Au-198Not Annotated
Lutetium Lu-177Not Annotated
Nickel sulfateNickel sulfate is used in allergenic testing.
Cobalt chlorideNot Annotated
Sodium molybdateNot Annotated
Bevacizumab zirconium Zr-89Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors).
Cobalt Co-60Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer).
Cuprous chlorideNot Annotated
Cobaltous sulfateA micronutrient found in some multivitamins.
MolybdateNot Annotated
Molybdenum trioxideNot Annotated
Zirconium dioxideNot Annotated
Hafnium oxideNot Annotated
Ammonium tetrathiomolybdateNot Annotated
Drugs & Drug Targets
DrugTargetType
IronTransferrin receptor protein 1target
IronEgl nine homolog 1target
IronHistone deacetylase 8target
IronAlpha-hemoglobin-stabilizing proteintarget
IronHemoglobin subunit alphatarget
IronFrataxin, mitochondrialtarget
IronFerritin heavy chaintarget
IronFlap endonuclease 1target
IronEndonuclease 8-like 1target
IronEndonuclease 8-like 2target
IronDNA polymerase betatarget
IronCeruloplasmintarget
IronSerotransferrintarget
ZincB1 bradykinin receptortarget
ZincMethylated-DNA--protein-cysteine methyltransferasetarget
ZincFructose-bisphosphate aldolase Atarget
ZincElongation factor 1-alpha 1target
ZincAlpha-enolasetarget
ZincGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
ZincNucleoside diphosphate kinase Atarget
ZincProtein disulfide-isomerasetarget
ZincProtein disulfide-isomerase A3target
ZincPeroxiredoxin-1target
ZincPhosphoserine phosphatasetarget
ZincTriosephosphate isomerasetarget
ZincElongation factor Tu, mitochondrialtarget
ZincEstrogen receptor alphatarget
ZincInterleukin-3target
ZincMetallothionein-2target
ZincCopper chaperone for superoxide dismutasetarget
ZincHistone deacetylase 1target
ZincHistone deacetylase 4target
ZincDNA-3-methyladenine glycosylasetarget
ZincSemenogelin-1target
ZincSuperoxide dismutase [Cu-Zn]target
ZincHistone deacetylase 8target
ZincApoptosis regulatory protein Sivatarget
ZincGlycine receptor subunit alpha-1target
ZincE3 ubiquitin-protein ligase Mdm2target
ZincInsulintarget
ZincUtrophintarget
ZincAspartoacylasetarget
ZincProtein S100-A8target
ZincProtein S100-A9target
ZincMatrix metalloproteinase-9target
ZincTumor protein p73target
ZincProtein S100-A2target
ZincCellular tumor antigen p53target
ZincMetallothionein-3target
ZincProgrammed cell death protein 6target
ZincDAN domain family member 5target
ZincMetallothionein-1Atarget
ZincAlpha-1B-glycoproteintarget
ZincAlpha-2-macroglobulintarget
ZincAngiotensinogentarget
ZincAlpha-2-HS-glycoproteintarget
ZincSerum amyloid P-componenttarget
ZincApolipoprotein A-Itarget
ZincApolipoprotein A-IItarget
ZincApolipoprotein A-IVtarget
ZincApolipoprotein B receptortarget
ZincApolipoprotein Etarget
ZincApolipoprotein L1target
ZincComplement C1q subcomponent subunit Btarget
ZincComplement C1q subcomponent subunit Ctarget
ZincComplement C1r subcomponenttarget
ZincComplement C1s subcomponenttarget
ZincComplement C3target
ZincComplement C4-Btarget
ZincC4b-binding protein alpha chaintarget
ZincC4b-binding protein beta chaintarget
ZincComplement C5target
ZincLys-63-specific deubiquitinase BRCC36target
ZincComplement component C8 alpha chaintarget
ZincComplement component C8 beta chaintarget
ZincComplement component C8 gamma chaintarget
ZincComplement factor Btarget
ZincComplement factor Htarget
ZincComplement factor Itarget
ZincClusterintarget
ZincCeruloplasmintarget
ZincCarboxypeptidase N catalytic chaintarget
ZincCarboxypeptidase N subunit 2target
ZincDermcidintarget
ZincDesmoplakintarget
ZincCoagulation factor XIItarget
ZincCoagulation factor XIII B chaintarget
ZincProthrombintarget
ZincFicolin-3target
ZincFibrinogen alpha chaintarget
ZincFibronectintarget
ZincGelsolintarget
ZincHemoglobin subunit alphatarget
ZincHemoglobin subunit betatarget
ZincHaptoglobin-related proteintarget
ZincHornerintarget
ZincInsulin-like growth factor-binding protein complex acid labile subunittarget
ZincIg alpha-1 chain C regiontarget
ZincIg mu chain C regiontarget
ZincImmunoglobulin kappa variable 1-17target
ZincIg kappa chain V-III region GOLtarget
ZincImmunoglobulin lambda variable 3-21target
ZincInter-alpha-trypsin inhibitor heavy chain H1target
ZincInter-alpha-trypsin inhibitor heavy chain H2target
ZincInter-alpha-trypsin inhibitor heavy chain H3target
ZincInter-alpha-trypsin inhibitor heavy chain H4target
ZincImmunoglobulin J chaintarget
ZincJunction plakoglobintarget
ZincPlasma kallikreintarget
ZincKininogen-1target
ZincKeratin, type II cytoskeletal 1target
ZincKeratin, type I cytoskeletal 10target
ZincKeratin, type I cytoskeletal 14target
ZincKeratin, type I cytoskeletal 16target
ZincKeratin, type II cytoskeletal 2 epidermaltarget
ZincKeratin, type II cytoskeletal 5target
ZincKeratin, type II cytoskeletal 6Atarget
ZincKeratin, type I cytoskeletal 9target
ZincAlpha-1-acid glycoprotein 2target
ZincN-acetylmuramoyl-L-alanine amidasetarget
ZincSerum paraoxonase/arylesterase 1target
ZincPregnancy zone proteintarget
ZincProtein S100-A7target
ZincSelenoprotein Ptarget
ZincAlpha-1-antitrypsintarget
ZincAlpha-1-antichymotrypsintarget
ZincKallistatintarget
ZincCorticosteroid-binding globulintarget
ZincHeparin cofactor 2target
ZincSex hormone-binding globulintarget
ZincSerotransferrintarget
ZincTransthyretintarget
ZincVitronectintarget
ZincAmyloid-like protein 1target
ZincAmyloid-like protein 2target
ZincAmyloid beta A4 proteintarget
ZincPoly [ADP-ribose] polymerase 1target
ZincCarbonic anhydrase 1enzyme
ManganeseCytoplasmic aconitate hydrataseenzyme
ManganeseIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
ManganeseIsocitrate dehydrogenase [NAD] subunit gamma, mitochondrialtarget
ManganeseTGF-beta-activated kinase 1 and MAP3K7-binding protein 1target
ManganeseArginase-1target
ManganeseSerotransferrintarget
ChromiumSerotransferrincarrier
ChromiumCytochrome b5target
CopperSuperoxide dismutase [Cu-Zn]enzyme
CopperAmiloride-sensitive amine oxidase [copper-containing]enzyme
CopperProtein-lysine 6-oxidaseenzyme
CopperHigh affinity copper uptake protein 1transporter
CopperNatural resistance-associated macrophage protein 2transporter
CopperSerum albumincarrier
CopperAlpha-2-macroglobulincarrier
CopperCeruloplasmincarrier
CopperCopper transport protein ATOX1carrier
CopperCopper-transporting ATPase 1transporter
CopperCopper-transporting ATPase 2transporter
CopperCopper chaperone for superoxide dismutasecarrier
CopperCytochrome c oxidase copper chaperonecarrier
CopperCytochrome c oxidase subunit 1enzyme
CopperTyrosinaseenzyme
CopperDopamine beta-hydroxylaseenzyme
CopperPeptidyl-glycine alpha-amidating monooxygenaseenzyme
CopperMonoamine oxidaseenzyme
CopperAngiogeninenzyme
CopperAmyloid beta A4 proteintarget
CopperHephaestincarrier
CopperMajor prion proteinenzyme
CopperAdenosylhomocysteinasetarget
CopperCoagulation factor Vcarrier
CopperCoagulation factor VIIIcarrier
CopperMetallothioneincarrier
CopperProbable low affinity copper uptake protein 2transporter
CopperHistone H2B type 1-C/E/F/G/Itarget
CopperGlyceraldehyde-3-phosphate dehydrogenasetarget
CopperNucleoside diphosphate kinase Atarget
CopperHistone H1.4target
CopperPeroxiredoxin-1target
CopperProtein S100-A8target
Copper40S ribosomal protein SAtarget
CopperActin, cytoplasmic 2target
CopperAlpha-enolasetarget
CopperElongation factor 1-alpha 1target
CopperKeratin, type II cytoskeletal 8target
CopperProtein disulfide-isomerasetarget
CopperProtein disulfide-isomerase A3target
Copper60 kDa heat shock protein, mitochondrialtarget
CopperHeat shock 70 kDa protein 13target
Copper78 kDa glucose-regulated proteintarget
CopperEndoplasmintarget
CopperSerotransferrintarget
CopperCell growth-regulating nucleolar proteintarget
Copper40S ribosomal protein S2target
CopperSerine/arginine-rich splicing factor 1target
CopperHeterogeneous nuclear ribonucleoproteins A2/B1target
CopperHeterogeneous nuclear ribonucleoprotein Htarget
CopperHeterogeneous nuclear ribonucleoprotein H3target
CopperCobalt-precorrin-5B C(1)-methyltransferasetarget
CopperHeterogeneous nuclear ribonucleoprotein Ltarget
CopperSplicing factor, proline- and glutamine-richtarget
CopperSplicing factor 3A subunit 2target
CopperReceptor of activated protein C kinase 1target
CopperAlpha-actinin-1target
CopperAminoacylase-1target
CopperAnnexin A4target
CopperAnnexin A5target
CopperCalreticulintarget
CopperPyruvate kinase PKMtarget
CopperAlcohol dehydrogenase [NADP(+)]target
CopperNADH-cytochrome b5 reductase 3target
CopperGlutathione reductase, mitochondrialtarget
CopperTransketolasetarget
CopperPeroxiredoxin-2target
CopperPeroxiredoxin-6target
CopperPeptidyl-prolyl cis-trans isomerase Atarget
CopperHeat shock cognate 71 kDa proteintarget
CopperHeat shock protein HSP 90-alphatarget
CopperProstaglandin E synthase 3target
CopperStress-induced-phosphoprotein 1target
CopperTranslation elongation factor 1 alpha 1-like 14target
CopperEukaryotic translation initiation factor 6target
CopperEukaryotic initiation factor 4A-Itarget
CopperGlucose-6-phosphate isomerasetarget
CopperL-lactate dehydrogenase A chaintarget
CopperPhosphoglycerate kinase 1target
CopperTubulin alpha 3C/D chaintarget
CopperTubulin beta chaintarget
CopperCofilin-1target
Copper14-3-3 protein beta/alphatarget
CopperAspartate aminotransferase, cytoplasmictarget
CopperGlutathione synthetasetarget
CopperHepatoma-derived growth factortarget
CopperIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
CopperChloride intracellular channel protein 1target
CopperProteasome activator complex subunit 1target
CopperPhosphatidylethanolamine-binding protein 1target
CopperPhosphoglycerate mutase 1target
CopperRan-specific GTPase-activating proteintarget
CopperUDP-glucose 6-dehydrogenasetarget
CopperBeta-2-microglobulintarget
CopperProtein SCO1 homolog, mitochondrialtarget
CopperAlternative prion proteintarget
CopperGlycine receptor subunit alpha-1target
CopperHuntingtintarget
CopperEndonuclease 8-like 1target
CopperEndonuclease 8-like 2target
CopperHephaestin-like protein 1target
CopperPlasminogen activator inhibitor 1target
CopperProtein S100-A2target
CopperProtein S100-A4target
CopperAlpha-synucleintarget
CopperBrain-derived neurotrophic factortarget
CopperProtein DJ-1target
CopperIslet amyloid polypeptidetarget
CopperTachykinin-3target
CopperAlpha-1B-glycoproteintarget
CopperAfamintarget
CopperAngiotensinogentarget
CopperAlpha-2-HS-glycoproteintarget
CopperSerum amyloid P-componenttarget
CopperApolipoprotein A-Itarget
CopperApolipoprotein A-IItarget
CopperApolipoprotein A-IVtarget
CopperApolipoprotein B receptortarget
CopperApolipoprotein C-IItarget
CopperApolipoprotein C-IIItarget
CopperApolipoprotein Dtarget
CopperApolipoprotein Etarget
CopperBeta-2-glycoprotein 1target
CopperZinc-alpha-2-glycoproteintarget
CopperComplement C1q subcomponent subunit Ctarget
CopperComplement C1s subcomponenttarget
CopperComplement C3target
CopperComplement C4-Btarget
CopperC4b-binding protein alpha chaintarget
CopperComplement C5target
CopperComplement component C8 beta chaintarget
CopperComplement component C9target
CopperComplement factor Htarget
CopperComplement factor Itarget
CopperTetranectintarget
CopperClusterintarget
CopperProthrombintarget
CopperComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
CopperGelsolintarget
CopperHemoglobin subunit alphatarget
CopperHemoglobin subunit betatarget
CopperChromobox protein homolog 5target
CopperHaptoglobin-related proteintarget
CopperInsulin-like growth factor-binding protein complex acid labile subunittarget
CopperIg gamma-1 chain C regiontarget
CopperIg gamma-4 chain C regiontarget
CopperIg kappa chain V-III region GOLtarget
CopperImmunoglobulin lambda-like polypeptide 1target
CopperInter-alpha-trypsin inhibitor heavy chain H2target
CopperKininogen-1target
CopperKeratin, type II cytoskeletal 1target
CopperKeratin, type I cytoskeletal 10target
CopperKeratin, type II cytoskeletal 2 epidermaltarget
CopperKeratin, type I cytoskeletal 9target
CopperLeucine-rich alpha-2-glycoproteintarget
CopperLumicantarget
CopperN-acetylmuramoyl-L-alanine amidasetarget
CopperPlasminogentarget
CopperSerum paraoxonase/arylesterase 1target
CopperPlatelet basic proteintarget
CopperAlpha-1-antitrypsintarget
CopperKallistatintarget
CopperCorticosteroid-binding globulintarget
CopperThyroxine-binding globulintarget
CopperAntithrombin-IIItarget
CopperHeparin cofactor 2target
CopperPigment epithelium-derived factortarget
CopperAlpha-2-antiplasmintarget
CopperPlasma protease C1 inhibitortarget
CopperTransthyretintarget
CopperVitronectintarget
CopperAmyloid-like protein 1target
SilverMetallothioneintarget
SilverCeruloplasmintarget
SilverSerum albumintarget
SilverAlpha-2-macroglobulintarget
TetrathiomolybdateAmyloid beta A4 proteintarget
Cupric ChlorideVitamin K-dependent protein Ctarget
Cupric ChlorideCystatin-Btarget
Ferric pyrophosphateFerritin light chaintarget
Ferric pyrophosphateHemoglobin subunit alphatarget
Ferric pyrophosphateHemoglobin subunit betatarget
Titanium dioxideMacrophage receptor MARCOtarget
Cupric oxideSerum albumincarrier
Cupric oxideCeruloplasmincarrier