N-substituted Glycines

Name
N-substituted Glycines
Accession Number
DBCAT001454
Description

AMINO ACIDS composed of GLYCINE substituted at the nitrogen rather than the usual carbon position, resulting in the loss of HYDROGEN BONDING donors. Polymers of these compounds are called PEPTOIDS.

Drugs
DrugDrug Description
SarcosineSarcosine has been investigated for the treatment of Schizophrenia.
Glycocholic acidThe glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
TioproninA thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria.
ThiorphanA potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
N,N-dimethylglycineNot Available
Glycochenodeoxycholic AcidA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed....
RacecadotrilAn anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea.
Drugs & Drug Targets
DrugTargetType
Glycocholic acidGastrotropintarget
Glycocholic acidSolute carrier organic anion transporter family member 1A2transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B1transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B3transporter
TioproninMyeloperoxidaseenzyme
ThiorphanNeprilysintarget
N,N-dimethylglycineMonomeric sarcosine oxidasetarget
Glycochenodeoxycholic Acid7-alpha-hydroxysteroid dehydrogenasetarget
Glycochenodeoxycholic AcidBile salt export pumptransporter
Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
Glycochenodeoxycholic AcidSodium/bile acid cotransportertransporter