Adipokines

Name
Adipokines
Accession Number
DBCAT001664
Description

Polypeptides produced by the ADIPOCYTES. They include LEPTIN; ADIPONECTIN; RESISTIN; and many cytokines of the immune system, such as TUMOR NECROSIS FACTOR-ALPHA; INTERLEUKIN-6; and COMPLEMENT FACTOR D (also known as ADIPSIN). They have potent autocrine, paracrine, and endocrine functions.

Drugs
DrugDrug Description
LeptinInvestigated for use/treatment in lipodystrophy and obesity.
MetreleptinA leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.
Drugs & Drug Targets
DrugTargetType
LeptinLeptin receptortarget
MetreleptinLeptin receptortarget