Dehydroepiandrosterone

All categories
Name
Dehydroepiandrosterone
Accession Number
DBCAT001749
Description

A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.

ATC Classification
Drugs
DrugDrug Description
Prasterone sulfateInvestigated for use/treatment in asthma and burns and burn infections.
Drugs & Drug Targets
DrugTargetType
Prasterone sulfateCytochrome P450 19A1enzyme
Prasterone sulfateCytochrome P450 3A7enzyme
Prasterone sulfateProstaglandin G/H synthase 2enzyme
Prasterone sulfateSolute carrier family 22 member 8transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1A2transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1B1transporter
Prasterone sulfateSolute carrier organic anion transporter family member 1B3transporter
Prasterone sulfateSolute carrier organic anion transporter family member 2B1transporter
Prasterone sulfateSolute carrier family 10 member 6transporter
Prasterone sulfateBile salt export pumptransporter