Somatropin and Somatropin Agonists

Name
Somatropin and Somatropin Agonists
Accession Number
DBCAT002095
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
SomatotropinA recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
MecaserminA recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH.
TesamorelinA growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
Mecasermin rinfabateMecasermin rinfabate was approved for treatment of severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) ....
LonapegsomatropinA human growth hormone indicated in the treatment of growth failure due to inadequate endogenous growth hormone secretion.
SomatrogonA long-acting recombinant human growth hormone used as the long-term treatment of pediatric patients who have growth failure due to growth hormone deficiency.
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
Drugs & Drug Targets
DrugTargetType
SermorelinGrowth hormone-releasing hormone receptortarget
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatotropinCytochrome P450 1A2enzyme
SomatotropinCytochrome P450 2C19enzyme
SomatotropinP-glycoprotein 1transporter
MecaserminInsulin-like growth factor 1 receptortarget
MecaserminInsulin-like growth factor-binding protein 3target
MecaserminInsulin receptortarget
MecaserminCation-independent mannose-6-phosphate receptortarget
MecaserminInsulin-like growth factor-binding protein 3carrier
MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
MecaserminInsulin-like growth factor-binding protein 1carrier
MecaserminInsulin-like growth factor-binding protein 2carrier
MecaserminInsulin-like growth factor-binding protein 4carrier
MecaserminInsulin-like growth factor-binding protein 5carrier
MecaserminInsulin-like growth factor-binding protein 6carrier
TesamorelinGrowth hormone-releasing hormone receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
Mecasermin rinfabateInsulin-like growth factor 1 receptortarget
Mecasermin rinfabateInsulin receptortarget
Mecasermin rinfabateCation-independent mannose-6-phosphate receptortarget
LonapegsomatropinCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
LonapegsomatropinGrowth hormone receptortarget
LonapegsomatropinProlactin receptortarget
LonapegsomatropinCytochrome P450 1A2enzyme
LonapegsomatropinCytochrome P450 2C19enzyme
LonapegsomatropinP-glycoprotein 1transporter
SomatrogonGrowth hormone receptortarget
SomapacitanCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanSerum albumincarrier
SomapacitanGrowth hormone receptortarget