Cardiac Therapy
- Name
- Cardiac Therapy
- Accession Number
- DBCAT002210 (DBCAT003655)
- Description
Not Available
- ATC Classification
- Drugs
Drug Drug Description Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Milrinone A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. Ranolazine An anti-anginal drug used for the treatment of chronic angina. Disopyramide A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. Ibutilide A class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Acetyldigitoxin Used for fast digitalization in congestive heart failure. Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage Adenosine A medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia. Moricizine An antiarrhythmic used to treat arrhythmias. Methoxamine An alpha adrenergic agonist used to treat hypotension. Nitroglycerin A nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures. Fenoldopam A dopamine D1 receptor agonist used for the short term management of hypertension. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Isosorbide dinitrate A vasodilator used to treat angina in coronary artery disease. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Levosimendan A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure. Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Isosorbide mononitrate A nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease. Procainamide A medication used to treat life threatening ventricular arrhythmias. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Deslanoside For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure. Ouabain For the treatment of atrial fibrillation and flutter and heart failure Arbutamine Used to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in... Amiodarone A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. Flecainide A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Mephentermine A sympathomimetic agent used in the treatment of hypotension. Digitoxin A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. Ajmaline An antiarrhythmic used to manage a variety of forms of tachycardias. Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Aprindine Aprindine is a cardiac depressant used in arrhythmias. Erythrityl tetranitrate For the prevention of angina. Camphor A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Dronedarone An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. Enoximone A selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure. Nesiritide A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. Acadesine Investigated for use/treatment in cardiac reperfusion injury, cardiovascular disorders, and coronary artery disease. Serelaxin Investigated for use/treatment in cardiovascular disorders, congestive heart failure, infertility, peripheral vascular disease, and scleroderma. Pentaerythritol tetranitrate Used for the treatment of angina pectoris . Tedisamil Investigated for use/treatment in arrhythmia, atrial fibrillation, and angina. Regadenoson A coronary vasodilator used in radionuclide myocardial perfusion imaging (MPI). Vernakalant An antiarrhythmic medication used to treat patients with atrial fibrillation. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Sparteine Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category... Etilefrine An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. Trimetazidine A piperazine derivative indicated as an adjunct therapy in symptomatic treatment of stable angina pectoris. Ivabradine A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. Nicorandil A vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina. Ubidecarenone A cofactor found in various dietary supplements. Molsidomine A long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction. Trapidil Used in the treatment of chronic stable angina . Imolamine Imolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic. Dopexamine Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Creatinolfosfate COP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease. COP has been investigated for the treatment of Diabetic Retinopathy. Phosphocreatine A cardioprotective agent indicated for use in cardiac surgery. Flosequinan Flosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in... Cymarin Not Annotated Bucladesine Not Annotated Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Propatyl nitrate Not Annotated Hexobendine Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has... Benziodarone Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout . It was withdrawn from France... Carbocromen Carbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development . Cloridarol Cloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s . Proscillaridin Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,... Amezinium metilsulfate Not Annotated Efloxate Not Annotated Cinepazet Not Annotated Cibenzoline Not Annotated Norfenefrine Not Annotated Oxyfedrine Not Annotated Linsidomine Not Annotated Metildigoxin A digitalis glycoside indicated in the treatment of acute and chronic heart failure. Methylpropylpropanediol dinitrate Not Annotated Lanatoside C Not Annotated Dimetofrine Not Annotated Angiotensinamide Not Annotated Gitoformate Not Annotated Prajmaline Not Annotated Heptaminol A cardiac stimulant and vasodilator indicated in the treatment of hemorrhoids and venolymphatic insufficiency. Aminoethyl nitrate Not Annotated Tiracizine Not Annotated Tenitramine Not Annotated Ethacizine Not Annotated Lorajmine Not Annotated Bunaftine Not Annotated Lorcainide Not Annotated Acetyldigoxin Not Annotated Gepefrine Not Annotated Dilazep Not Annotated Trolnitrate Not Annotated Meldonium Not Annotated Peruvoside Not Annotated Prenalterol Not Annotated Xamoterol Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... Etafenone Etafenone is a vasodilator. Fosfructose A phosphorylated form of fructose indicated in the treatment of hypophosphatemia. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Alprostadil A prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis. Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Bretylium A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. Hydroquinidine A medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm. Vericiguat A soluble guanylate cyclase stimulator used to reduce heart failure-related hospitalization and cardiovascular death in patients with chronic systolic heart failure. Mavacamten A myosin inhibitor used to treat obstructive hypertrophic cardiomyopathy. - Drugs & Drug Targets