Serotonin 5-HT3 Receptor Antagonists
- Name
- Serotonin 5-HT3 Receptor Antagonists
- Accession Number
- DBCAT002341 (DBCAT001738, DBCAT003341, DBCAT003736)
- Description
Drugs that bind to but do not activate SEROTONIN 5-HT3 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT3 RECEPTOR AGONISTS.
- ATC Classification
- Drugs
Drug Drug Description Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. Dolasetron An antinauseant and antiemetic used in chemotherapy and postoperatively. Granisetron A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. Ondansetron A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. Tropisetron A 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. Esmirtazapine Investigated for use/treatment in insomnia and sleep disorders. - Drugs & Drug Targets