Sympathomimetics in Glaucoma Therapy

Name
Sympathomimetics in Glaucoma Therapy
Accession Number
DBCAT002382
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
ApraclonidineAn alpha adrenergic agonist used to treat raised intraocular pressure.
BrimonidineAn alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
Drugs & Drug Targets
DrugTargetType
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
ApraclonidineAlpha-2A adrenergic receptortarget
ApraclonidineAlpha-1A adrenergic receptortarget
ApraclonidineAlpha-2B adrenergic receptortarget
BrimonidineAlpha-2A adrenergic receptortarget
BrimonidineAlpha-2B adrenergic receptortarget
BrimonidineAlpha-2C adrenergic receptortarget
BrimonidineAldehyde oxidaseenzyme
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme