Serotonin Modulators
- Name
- Serotonin Modulators
- Accession Number
- DBCAT002706
- Description
Not Available
- Drugs
Drug Drug Description Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). Fluvoxamine A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Citalopram A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Amitriptyline A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Protriptyline A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision. Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. Meperidine An opioid agonist with analgesic and sedative properties used to manage severe pain. Imipramine A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. Duloxetine A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Nortriptyline A tricyclic antidepressant used in the treatment of depression. Amoxapine A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Paroxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. Trimipramine A tricyclic antidepressant used to treat depression. Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder. Phenelzine A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Almotriptan A 5-HT1B/1D receptor agonist used to treat migraines. Maprotiline A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression. Naratriptan A 5-HT1B/1D receptor agonist used to treat migraines. Rizatriptan A triptan used to treat migraines with or without aura. Frovatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Sertraline A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Nefazodone An antidepressant used in the treatment of depression. Desipramine A tricyclic antidepressant used in the treatment of depression. Procarbazine An antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Escitalopram A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Clomipramine A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. Isocarboxazid A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs. Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Lithium cation A drug used for the management of bipolar disorder and other psychiatric conditions. Rasagiline An irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa. Lorcaserin A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. Milnacipran A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. Tapentadol An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Levomilnacipran A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults. Tedizolid phosphate An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections. Tianeptine An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder. Tenamfetamine An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons... Zolmitriptan A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults. Eletriptan A triptan used for the treatment of migraines. Sibutramine A norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. Dapoxetine A selective serotonin reuptake inhibitor used in the treatment of premature ejaculation. Indalpine Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse... Zimelidine For the treatment of depression. Alaproclate Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity... Ritanserin Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders. Mianserin A tetracyclic antidepressant with therapeutic activity similar to amitriptyline used to treat depression and anxiety. Mazindol A sympathomimetic used to treat obesity in combination with lifestyle modifications. Chlorpheniramine A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. Dexmethylphenidate A norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies. Dosulepin A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential. Etoperidone Etoperidone has been studied for the treatment of depression , tremors in Parkinson, extrapyramidal symptoms and male impotence . It is not certain if it was ever approved and marketed... Seproxetine Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an... Lithium citrate Lithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment. Lithium carbonate A medication used to treat manic episodes of bipolar disorder. Lorpiprazole In 2016, lorpiprazole was classified in the "Chemical structure-related drug-like criteria of global approved drugs" as an antipsychotic and anxiolytic. An antipsychotic is a medication used to treat a state... Lumateperone A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia. Flibanserin A 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). - Drugs & Drug Targets