NMDA Receptor Antagonists
- Name
- NMDA Receptor Antagonists
- Accession Number
- DBCAT002723
- Description
Not Available
- Drugs
Drug Drug Description Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Amantadine A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. Ketamine A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. Orphenadrine A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. Meperidine An opioid agonist with analgesic and sedative properties used to manage severe pain. Agmatine Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... Ifenprodil N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer... Tenocyclidine Because of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors. Haloperidol An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. Felbamate An anticonvulsant used to treat severe epilepsy. Memantine An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. Halothane A general inhalation anesthetic used for the induction and maintenance of general anesthesia. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Profenamine An antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease. Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. Ethanol For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... Phencyclidine A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like... Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Esketamine A NMDA receptor antagonist used for treatment-resistant depression. - Drugs & Drug Targets