Cytochrome P-450 CYP2C9 Inducers (weak)

Name
Cytochrome P-450 CYP2C9 Inducers (weak)
Accession Number
DBCAT003039
Description

Not Available

Drugs
DrugDrug Description
DelafloxacinA fluoroquinolone antibiotic used to treat skin and skin structure infections.
ApalutamideAn androgen receptor inhibitor used to treat non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer.
AvatrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
Drugs & Drug Targets
DrugTargetType
DelafloxacinUDP-glucuronosyltransferase 1-1enzyme
DelafloxacinUDP-glucuronosyltransferase 1-3enzyme
DelafloxacinUDP-glucuronosyltransferase 2B15enzyme
DelafloxacinDNA topoisomerase 4 subunit Atarget
DelafloxacinDNA gyrase subunit Atarget
DelafloxacinCytochrome P450 2E1enzyme
DelafloxacinCytochrome P450 2C9enzyme
DelafloxacinCytochrome P450 3A4enzyme
DelafloxacinATP-binding cassette sub-family B member 5transporter
DelafloxacinATP-binding cassette sub-family G member 2transporter
DelafloxacinSerum albumincarrier
ApalutamideAndrogen receptortarget
ApalutamideCytochrome P450 3A4enzyme
ApalutamideCytochrome P450 2C8enzyme
ApalutamideCytochrome P450 2C19enzyme
ApalutamideCytochrome P450 2C9enzyme
ApalutamideP-glycoprotein 1transporter
ApalutamideATP-binding cassette sub-family G member 2transporter
ApalutamideSolute carrier organic anion transporter family member 1B1transporter
ApalutamideSolute carrier family 22 member 2transporter
ApalutamideSolute carrier family 22 member 8transporter
ApalutamideMultidrug and toxin extrusion protein 2transporter
ApalutamideGABA(A) Receptortarget
ApalutamideMultidrug and toxin extrusion protein 1transporter
ApalutamideSerum albumincarrier
AvatrombopagATP-binding cassette sub-family G member 2target
AvatrombopagCytochrome P450 2C8enzyme
AvatrombopagCytochrome P450 2C9enzyme
AvatrombopagThrombopoietin receptortarget
AvatrombopagP-glycoprotein 1transporter
AvatrombopagSolute carrier family 22 member 8target
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
IsavuconazoleCytochrome P450 3A4enzyme
IsavuconazoleCytochrome P450 3A5enzyme
IsavuconazoleCytochrome P450 2C8enzyme
IsavuconazoleCytochrome P450 2C9enzyme
IsavuconazoleCytochrome P450 2C19enzyme
IsavuconazoleCytochrome P450 2D6enzyme
IsavuconazoleCytochrome P450 2B6enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
IsavuconazoleP-glycoprotein 1transporter
IsavuconazoleATP-binding cassette sub-family G member 2transporter
IsavuconazoleSolute carrier family 22 member 2transporter
IsavuconazoleLanosterol 14-alpha demethylasetarget
IsavuconazolePotassium voltage-gated channel subfamily H member 2target
IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsavuconazoleG protein-activated inward rectifier potassium channel 2target
IsavuconazoleG protein-activated inward rectifier potassium channel 3target
IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
IsavuconazolePotassium voltage-gated channel subfamily A member 5target
IsavuconazolePotassium voltage-gated channel subfamily D member 3target
IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
IsavuconazoleSodium channel protein type 5 subunit alphatarget
TicagrelorCytochrome P450 3A4enzyme
TicagrelorP2Y purinoceptor 12target
TicagrelorP-glycoprotein 1transporter
TicagrelorCytochrome P450 2C9enzyme
TicagrelorSerum albumincarrier
TicagrelorCytochrome P450 3A5enzyme
TicagrelorCytochrome P450 2B6enzyme