Progestin-containing Intrauterine Device

Accession Number

DBCAT003338

Description

Not Available

Drugs

Drug	Drug Description
Progesterone	A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
Levonorgestrel	A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.

Drugs & Drug Targets

Drug	Target	Type
Progesterone	Progesterone receptor	target
Progesterone	Estrogen receptor alpha	target
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Progesterone	Cytochrome P450 2C19	enzyme
Progesterone	Cytochrome P450 2C9	enzyme
Progesterone	Cytochrome P450 3A4	enzyme
Progesterone	Cytochrome P450 3A5	enzyme
Progesterone	Cytochrome P450 3A7	enzyme
Progesterone	P-glycoprotein 1	transporter
Progesterone	Solute carrier family 22 member 2	transporter
Progesterone	Solute carrier family 22 member 1	transporter
Progesterone	Solute carrier family 22 member 3	transporter
Progesterone	Bile salt export pump	transporter
Progesterone	Multidrug resistance-associated protein 1	transporter
Progesterone	Sodium/bile acid cotransporter	transporter
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Progesterone	Cytochrome P450 1A1	enzyme
Progesterone	Cytochrome P450 1B1	enzyme
Progesterone	Cytochrome P450 2A6	enzyme
Progesterone	Cytochrome P450 2D6	enzyme
Progesterone	Mineralocorticoid receptor	target
Progesterone	Kappa-type opioid receptor	target
Progesterone	Alpha-1-acid glycoprotein 1	target
Progesterone	Glucocorticoid receptor	target
Progesterone	Androgen receptor	target
Progesterone	Sex hormone-binding globulin	target
Progesterone	Solute carrier organic anion transporter family member 1B1	transporter
Progesterone	ATP-binding cassette sub-family G member 2	transporter
Progesterone	Estrogen receptor beta	target
Progesterone	Solute carrier organic anion transporter family member 1B3	transporter
Levonorgestrel	Progesterone receptor	target
Levonorgestrel	Estrogen receptor alpha	target
Levonorgestrel	3-oxo-5-alpha-steroid 4-dehydrogenase 1	target
Levonorgestrel	Cytochrome P450 3A4	enzyme
Levonorgestrel	Androgen receptor	target
Levonorgestrel	Sex hormone-binding globulin	target
Levonorgestrel	Glucocorticoid receptor	target
Levonorgestrel	Cytochrome P450 3A5	enzyme