Nitrates and Nitrites

Name
Nitrates and Nitrites
Accession Number
DBCAT003688
Description

Not Available

Drugs
DrugDrug Description
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
NitroglycerinA nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
Drugs & Drug Targets
DrugTargetType
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
Nitric OxideNitric oxide synthase, endothelialtarget
NitroglycerinAtrial natriuretic peptide receptor 1target
NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
NitroprussideAtrial natriuretic peptide receptor 1target
NitroprussideCytochrome P450 1A1enzyme