Agents causing hyperkalemia
- Name
- Agents causing hyperkalemia
- Accession Number
- DBCAT003960
- Description
Drugs that produce elevated potassium serum concentration as part of its side effects
- Drugs
Drug Drug Description Aliskiren A direct renin inhibitor used to manage hypertension. Canagliflozin A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Potassium chloride A potassium salt used to treat hypokalemia. Potassium cation Potassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions. Potassium citrate An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. Potassium bicarbonate An ingredient used as an antacid or to treat hypokalemia. Potassium acetate A medication used to treat hypokalemia. Triamterene A potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. Amiloride A pyrizine compound used to treat hypertension and congestive heart failure. Spironolactone An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. Danaparoid A heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT. Heparin An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation. Enoxaparin A low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction. Sulodexide A drug used to treat chronic venous ulcers in the legs. Bemiparin An ultra-low molecular weight heparin (ultra-LMWH) used to prevent thromboembolism following surgery and extracorporeal clotting during dialysis. Nadroparin A low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction. Reviparin By the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of... Tinzaparin A low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin. Parnaparin A low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis. Certoparin A low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis. Dalteparin A low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction. Ardeparin For prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery. Ramipril An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Trandolapril A prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction. Benazepril An ACE inhibitor prodrug used to treat hypertension. Enalapril A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. Moexipril An angiotensin converting enzyme inhibitor prodrug used to treat hypertension. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Perindopril An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. Quinapril An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Cilazapril An ACE inhibitor used for the management of hypertension and heart failure. Spirapril Spirapril is an ACE inhibitor class drug used to treat hypertension. Enalaprilat An antihypertensive agent used for the management of hypertension when oral therapy is not practical. Temocapril Temocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction). Zofenopril An ACE inhibitor indicated in the treatment of hypertension. Omapatrilat For the treatment of hypertension. Imidapril An ACE inhibitor used in the treatment of essential hypertension. Delapril An ACE inhibitor indicated in the treatment of essential hypertension. Rescinnamine For the treatment of hypertension. Benazeprilat Not Annotated Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Ramiprilat The active metabolite of the prodrug Ramipril. Perindoprilat The active metabolite of the prodrug Perindopril. Quinaprilat The active metabolite of the prodrug quinapril. Olmesartan An angiotensin receptor blocker (ARB) used in the treatment of hypertension. Candesartan An angiotensin-receptor blocker indicated in the treatment of hypertension. Candesartan cilexetil An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy. Irbesartan An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure. Tasosartan Tasosartan is infrequently in the treatment of hypertension and heart failure. Saralasin Not Annotated Fimasartan An angiotensin II receptor antagonist (ARB) used to treat hypertension and heart failure. Valsartan An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. Losartan An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. Telmisartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Forasartan For the treatment of hypertension. Saprisartan Saprisartan is used in the treatment of hypertension and heart failure. Azilsartan medoxomil An angiotensin II receptor blocker used to treat hypertension alone or in combination with other antihypertensive agents, such as chlorthalidone. Eprosartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Itraconazole An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. Sotalol A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. Alprenolol For the treatment of hypertension, angina, and arrhythmia Penbutolol A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Bopindolol For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Bupranolol Used to manage hypertension and tachycardia. Also used to treat glaucoma. Cloranolol Not Annotated Mepindolol Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. Tertatolol Tertatolol is a beta blocker. Timolol A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. Esmolol A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension. Betaxolol A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. Atenolol A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Bisoprolol A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Levobunolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metipranolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Nebivolol A beta blocking agent used to treat hypertension and aid in the management of heart failure. Bevantolol For the treatment of angina pectoris and hypertension. Practolol Used in the emergency treatment of cardiac arrhythmias. Celiprolol A beta-blocker for the management of hypertension and angina pectoris. Bufuralol Bufuralol is a new, non-selective -adrenoceptor blocking agent. Indenolol Indenolol is a drug of the beta-adrenergic blocker class. Befunolol Used in the management of open angle glaucoma. PMID: 12480285. Arotinolol Artinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is... Talinolol Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. Landiolol An ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia. Bucindolol Bucindolol has been investigated in Heart Failure. Epanolol Epanolol is an beta blocker. Esatenolol Esatenolol is a beta blocker. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. Levobetaxolol Used in the treatment of open-angle glaucoma and ocular hypertension [FDA Label]. Anisodamine Anisodamine has been investigated for the treatment of Intestinal Diseases. Cyclosporine A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Mannitol A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. Mannitol busulfan Mm has been used in trials studying the treatment of Cocaine Dependence and Diabetes Mellitus, Type 2. Penicillin G Acyl-Serine Not Available Pentamidine An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Tacrolimus A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. Trimethoprim An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. Canrenoic acid An aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels. Canrenone An antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure). Ammonium chloride Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium... Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. Tolvaptan A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia. Nicorandil A vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina. Aceclofenac Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Acemetacin A NSAID indicated in the treatment of pain and inflammation. Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. Alclofenac Alclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies. Alminoprofen Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. Aminophenazone An analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine. Antipyrine An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. Antrafenine Antrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain. Azapropazone Not Available Balsalazide An aminosalicylate used to treat ulcerative colitis. Bendazac A non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions. Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Benzydamine A locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy. Bromfenac An NSAID used to treat postoperative pain and inflammation of the eye. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Bumadizone Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis... Carbaspirin calcium An NSAID indicated in the treatment of short term pain and fever. Carprofen For use as a pain reliever in the treatment of joint pain and post-surgical pain. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Cimicoxib Investigated for use/treatment in depression. Clonixin An NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders. Dexibuprofen A pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. Dexketoprofen An NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Difenpiramide Not Annotated Diflunisal An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. Droxicam Droxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis . Epirizole Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain. Ethenzamide Not Annotated Etodolac An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. Etofenamate An NSAID used to treat muscle and joint pain. Etoricoxib A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. Felbinac Not Available Fenbufen Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is... Fenoprofen An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. Fentiazac Not Annotated Feprazone Not Annotated Firocoxib Used for the treatment of pain inflammation and fever in horses and dogs. Floctafenine An anti-inflammatory analgesic used to manage mild to moderate acute pain. Flunixin Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form.... Flunoxaprofen Not Annotated Flurbiprofen An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Guacetisal Not Annotated Ibuprofen An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Imidazole salicylate Not Annotated Indobufen A reversible platelet aggregation inhibitor used to prevent coronary and peripheral artery occlusion. Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. Indoprofen A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. Isoxicam Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. Kebuzone Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug. Ketoprofen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. Ketorolac An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. Lonazolac Not Annotated Lornoxicam An NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis. Loxoprofen An NSAID used to treat pain and inflammation in musculoskeletal conditions. Lumiracoxib For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults. Magnesium salicylate An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. Meclofenamic acid An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. Mefenamic acid An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. Mesalazine An aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved. Metamizole An antipyretic and analgesic drug used to relieve severe and persistent fever and pain. Mofebutazone Not Annotated Morniflumate An NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems. Nabumetone An NSAID used to treat osteoarthritis and rheumatoid arthritis. Naproxen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Nifenazone Not Annotated Niflumic acid A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma. Nimesulide A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Nitroaspirin Nitroaspirin has been investigated for the treatment of Intermittent Claudication. NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Olsalazine An anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis. Oxaprozin An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Oxyphenbutazone A nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. Parecoxib A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. Phenylbutazone An NSAID used to treat backache and ankylosing spondylitis. Piroxicam An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. Pirprofen Not Annotated Pranoprofen A topical anti-inflammatory agent used for the treatment of non-infectious inflammatory conditions such as blepharitis and conjunctivitis. Pranoprofen ophthalmic solution may also be used post-operatively to manage inflammation. Proglumetacin A non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Propyphenazone Not Annotated Proquazone Not Annotated Robenacoxib Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs. Rofecoxib A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. Salicylamide Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Salsalate A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . Sulfasalazine A salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Sulindac An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. Suprofen An NSAID used to prevent pupil constriction in ocular surgery. Suxibuzone Not Annotated Talniflumate Talnifumate is a phthalidyl ester of nifumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis and osteoarthritis ,... Tenidap Not Annotated Tenoxicam An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis. Tepoxalin Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused... Tiaprofenic acid A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. Tinoridine Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults). Tolfenamic acid In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. Tolmetin An NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis. Trolamine salicylate A medication used to relieve minor aches and pains of the muscles and joints. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Zomepirac Zomepirac was indicated for the management of mild to severe pain. Benorilate Not Annotated Dantrolene A direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis. Agmatine Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... Amiodarone A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. Amlodipine A calcium channel blocker used to treat hypertension and angina. Aranidipine Aranidipine has been used for many years to treat angina pectoris and hypertension. Azelnidipine For the treatment of hypertension. Barnidipine A calcium channel blocker used to treat various forms of hypertension. Bencyclane A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. Benidipine A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. Bepridil For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). Bioallethrin Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. Carboxyamidotriazole Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. Cilnidipine A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension. Cinnarizine A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Cyclandelate A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. Darodipine Darodipine is a calcium channel blocker. Dexniguldipine Not Annotated Dexverapamil Not Annotated Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Dotarizine A calcium antagonist used to treat and prevent migraines. Efonidipine For the treatment of hypertension. Emopamil Prevents renal injury after warm & cold ischemia. Eperisone An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles. Ethosuximide An anticonvulsant used to treat petit mal seizures. Felodipine A calcium channel blocker used to treat hypertension. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Fish oil A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. Flunarizine A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. Fluspirilene An antipsychotic agent used in the treatment of schizophrenia. Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Lacidipine A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. Lamotrigine A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. Lercanidipine A calcium channel blocker for the management of hypertension. Lidoflazine Not Annotated Lomerizine Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated... Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Methsuximide A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. Mibefradil For the treatment of angina and high blood pressure. Naftopidil Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Niguldipine Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. Niludipine Niludipine is a calcium channel blocker. Nilvadipine A calcium channel blocker used to manage arterial hypertension. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Nitrendipine A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension. Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Penfluridol Not Annotated Perhexiline For the management of severe angina pectoris. Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Seletracetam Investigated for use/treatment in epilepsy. Terodiline Not Annotated Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Tetrandrine Not Annotated Tranilast For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Trimethadione An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. Vinpocetine A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease. WIN 55212-2 WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Nitrofurantoin An antibiotic used to treat urinary tract infections. Potassium A medication used to treat hypokalemic conditions and to clear the colon prior to colonoscopy. Finerenone A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes. - Drugs & Drug Targets