Agents causing angioedema
- Name
- Agents causing angioedema
- Accession Number
- DBCAT004043
- Description
Medications known to cause angioedema, a swelling occurring in the lower layer of skin and tissue just under the skin or mucous membranes. The swelling may occur in the face, tongue, larynx, abdomen, or arms and legs. Drug-induced angioedema is caused via various mechanisms.
- Drugs
Drug Drug Description Streptokinase A purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism. Conjugated estrogens A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Ibuprofen An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. Pregabalin An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. Sirolimus An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors. Temsirolimus A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR. Sacubitril A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Icatibant A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). Valsartan An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. Losartan An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. Telmisartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Forasartan For the treatment of hypertension. Saprisartan Saprisartan is used in the treatment of hypertension and heart failure. Azilsartan medoxomil An angiotensin II receptor blocker used to treat hypertension alone or in combination with other antihypertensive agents, such as chlorthalidone. Eprosartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Gemigliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Evogliptin Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. Gosogliptin Gosogliptin has been used in trials studying the treatment of Renal Insufficiency, Chronic. Dutogliptin Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II. Carmegliptin Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2. Bisegliptin Investigated for use/treatment in diabetes mellitus type 2. AMG-222 Investigated for use/treatment in diabetes mellitus type 2. Teneligliptin Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus. Omarigliptin Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency. Anagliptin Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors. Sitagliptin An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Vildagliptin A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Ramipril An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Trandolapril A prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction. Benazepril An ACE inhibitor prodrug used to treat hypertension. Enalapril A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. Moexipril An angiotensin converting enzyme inhibitor prodrug used to treat hypertension. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Perindopril An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. Quinapril An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Cilazapril An ACE inhibitor used for the management of hypertension and heart failure. Spirapril Spirapril is an ACE inhibitor class drug used to treat hypertension. Enalaprilat An antihypertensive agent used for the management of hypertension when oral therapy is not practical. Temocapril Temocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction). Zofenopril An ACE inhibitor indicated in the treatment of hypertension. Omapatrilat For the treatment of hypertension. Imidapril An ACE inhibitor used in the treatment of essential hypertension. Delapril An ACE inhibitor indicated in the treatment of essential hypertension. Rescinnamine For the treatment of hypertension. Benazeprilat Not Annotated Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Ramiprilat The active metabolite of the prodrug Ramipril. Perindoprilat The active metabolite of the prodrug Perindopril. Quinaprilat The active metabolite of the prodrug quinapril. Trandolaprilat The active metabolite of the prodrug Trandolapril. Moexiprilat The active metabolite of the prodrug Moexipril. Quinoline Yellow WS A yellow colouring used around the world as a dye for food and medications. Alteplase A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Urokinase A low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines. Reteplase A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Anistreplase A form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Tenecteplase A modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Lanoteplase Investigated for use/treatment in myocardial infarction. Amediplase Investigated for use/treatment in myocardial infarction and thrombosis. Saruplase Not Annotated - Drugs & Drug Targets