Decreased Coagulation Factor Activity

Accession Number

DBCAT004167

Description

Not Available

Drugs

Drug	Drug Description
Protein C	A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Antithrombin Alfa	A recombinant antithrombin used to treat peri-operative and peripartum thromboembolic events in hereditary antithrombin deficiency.
Citric acid	An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
Edetic acid	A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.

Drugs & Drug Targets

Drug	Target	Type
Protein C	Coagulation factor V	target
Protein C	Coagulation factor VIII	target
Antithrombin Alfa	Prothrombin	target
Antithrombin Alfa	Coagulation factor X	target
Citric acid	Beta-lactamase 2	target
Citric acid	Aldose reductase	target
Citric acid	Citrate synthase, mitochondrial	target
Citric acid	Proto-oncogene tyrosine-protein kinase Src	target
Citric acid	Ribonuclease pancreatic	target
Citric acid	Isocitrate dehydrogenase [NADP]	target
Citric acid	Eosinophil cationic protein	target
Citric acid	Beta-lactamase	target
Citric acid	Fumarate hydratase class II	target
Citric acid	6-phosphogluconolactonase	target
Citric acid	L-amino-acid oxidase	target
Citric acid	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	target
Citric acid	Cytochrome c peroxidase	target
Citric acid	Hepatocyte growth factor-regulated tyrosine kinase substrate	target
Citric acid	Invasin	target
Citric acid	Intron-associated endonuclease 1	target
Citric acid	Short tail fiber protein	target
Citric acid	Malate dehydrogenase, mitochondrial	target
Citric acid	N5-carboxyaminoimidazole ribonucleotide mutase	target
Citric acid	50S ribosomal protein L4	target
Citric acid	Carboxypeptidase B	target
Citric acid	Hexon protein	target
Citric acid	Riboflavin biosynthesis protein RibF	target
Citric acid	Beta-fructosidase	target
Citric acid	Putative stringent starvation protein A	target
Citric acid	Citrate synthase	target
Citric acid	RNA 3'-terminal phosphate cyclase	target
Citric acid	U6 snRNA-associated Sm-like protein LSm6	target
Citric acid	Pleckstrin homology domain-containing family A member 1	target
Citric acid	Fe(3+)-binding periplasmic protein	target
Citric acid	Signal recognition particle receptor FtsY	target
Citric acid	Nicotinate-nucleotide adenylyltransferase	target
Citric acid	N utilization substance protein B homolog	target
Citric acid	Complement component C8 gamma chain	target
Citric acid	Ribonucleoside-diphosphate reductase subunit beta	target
Citric acid	Glutamine synthetase 1	target
Citric acid	Citrate synthase	target
Citric acid	Prostaglandin F synthase	target
Citric acid	Adenine phosphoribosyltransferase	target
Citric acid	Glucose-1-phosphate thymidylyltransferase	target
Citric acid	Glyoxalase family protein	target
Citric acid	Laccase domain protein YfiH	target
Citric acid	Ribose-5-phosphate isomerase A	target
Citric acid	GMP synthase [glutamine-hydrolyzing]	target
Citric acid	Inosine triphosphate pyrophosphatase	target
Citric acid	Lysozyme	target
Citric acid	Glycerol uptake operon antiterminator regulatory protein	target
Citric acid	3-carboxy-cis,cis-muconate cycloisomerase	target
Citric acid	Pyruvate decarboxylase	target
Citric acid	Solute carrier organic anion transporter family member 2B1	transporter
Citric acid	Metallo-beta-lactamase type 2	target
Edetic acid	Lead	target
Edetic acid	Iron	target
Edetic acid	Manganese cation	target
Edetic acid	Adenosine deaminase	enzyme
Edetic acid	Serum paraoxonase/lactonase 3	enzyme
Edetic acid	Cytochrome P450 19A1	enzyme