Cytochrome P-450 CYP3A5 Inhibitors (weak)
- Name
- Cytochrome P-450 CYP3A5 Inhibitors (weak)
- Accession Number
- DBCAT004488
- Description
Not Available
- Drugs
Drug Drug Description Acalabrutinib A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. Indinavir A protease inhibitor used to treat HIV infection. Fluconazole A triazole antifungal used to treat various fungal infections including candidiasis. Amlodipine A calcium channel blocker used to treat hypertension and angina. Osilodrostat An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism. Cimetidine A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. Dronabinol A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Cannabinol Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa. Olaparib A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. - Drugs & Drug Targets