Cytochrome P-450 CYP3A5 Inducers (strength unknown)

Name
Cytochrome P-450 CYP3A5 Inducers (strength unknown)
Accession Number
DBCAT004490
Description

Not Available

Drugs
DrugDrug Description
PhenytoinAn anticonvulsant drug used in the prophylaxis and control of various types of seizures.
DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
OxcarbazepineAn anti-epileptic used in the treatment of partial-onset seizures.
ReserpineFor the treatment of hypertension
ArmodafinilA stimulant used to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea, narcolepsy, or shift work disorder.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
FluticasoneA corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD.
Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
Betamethasone phosphateA fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Clobetasol propionateA corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
Clocortolone acetateNot Annotated
CloprednolA glucocorticoid indicated in the treatment of arthritis and asthma.
CortisoneA naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to...
Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
CortivazolCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
Dexamethasone isonicotinateDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
FluocortoloneA glucocorticoid used topically for localized skin reactions and also orally for systemic use.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
FluprednideneFluprednidene is a corticosteroid.
Fluprednidene acetateA corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses.
HalometasoneA corticosteroid indicated in the treatment of corticosteroid responsive dermatoses.
MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
Melengestrol acetateA 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus.
MeprednisoneNot Annotated
Methylprednisolone hemisuccinateA water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
MometasoneA corticosteroid with no indications.
Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
Prednisolone hemisuccinateA corticosteroid indicated in the treatment of anaphylaxis, asthma, edema, organ rejection, and other indications.
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Prednisone acetateNot Annotated
PrednylidenePrednylidene is an experimental systemic glucocorticoid.
RimexoloneA glucocorticoid used to treat inflammation of the eye.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
PralsetinibA RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
ThalidomideA medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
LevoketoconazoleOne of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.
OlaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
CariprazineAn atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
PirtobrutinibA kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
TezacaftorA medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis.
Drugs & Drug Targets
DrugTargetType
PhenytoinSodium channel protein type 5 subunit alphatarget
PhenytoinSodium channel protein type 1 subunit alphatarget
PhenytoinCytochrome P450 2C8enzyme
PhenytoinCytochrome P450 2C19enzyme
PhenytoinCytochrome P450 2C9enzyme
PhenytoinCytochrome P450 2B6enzyme
PhenytoinCytochrome P450 3A5enzyme
PhenytoinSerum albumincarrier
PhenytoinCytochrome P450 3A4enzyme
PhenytoinSolute carrier organic anion transporter family member 1C1transporter
PhenytoinP-glycoprotein 1transporter
PhenytoinCanalicular multispecific organic anion transporter 1transporter
PhenytoinCytochrome P450 11B1, mitochondrialenzyme
PhenytoinCytochrome P450 3A7enzyme
PhenytoinNuclear receptor subfamily 1 group I member 2target
PhenytoinSodium channel subunit beta-1target
PhenytoinSodium channel protein type 3 subunit alphatarget
PhenytoinUDP-glucuronosyltransferase 1-1enzyme
PhenytoinUDP-glucuronosyltransferase 1-6enzyme
PhenytoinUDP-glucuronosyltransferase 1-9enzyme
PhenytoinThyroxine-binding globulincarrier
PhenytoinPotassium voltage-gated channel subfamily H member 2target
PhenytoinVoltage-dependent L-type calcium channeltarget
PhenytoinSodium channel protein type 2 subunit alphatarget
PhenytoinSodium channel protein type 8 subunit alphatarget
PhenytoinGABA(A) Receptortarget
PhenytoinCytochrome P450 1A2enzyme
PhenytoinCytochrome P450 2A6enzyme
PhenytoinCytochrome P450 2D6enzyme
PhenytoinCytochrome P450 2E1enzyme
PhenytoinEpoxide hydrolase 1enzyme
PhenytoinUDP-glucuronosyltransferase 1-4enzyme
PhenytoinCatechol O-methyltransferaseenzyme
PhenytoinNAD(P)H dehydrogenase [quinone] 1enzyme
PhenytoinCytochrome P450 2C18enzyme
DaunorubicinDNAtarget
DaunorubicinCytochrome P450 3A5enzyme
DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DaunorubicinP-glycoprotein 1transporter
DaunorubicinMultidrug resistance-associated protein 1transporter
DaunorubicinMultidrug resistance-associated protein 6transporter
DaunorubicinMultidrug resistance-associated protein 7transporter
DaunorubicinATP-binding cassette sub-family G member 2transporter
DaunorubicinDNA topoisomerase 2-alphatarget
DaunorubicinDNA topoisomerase 2-betatarget
DaunorubicinCytochrome P450 1B1enzyme
DaunorubicinCytochrome P450 3A4enzyme
DaunorubicinAldose reductaseenzyme
DaunorubicinCarbonyl reductase [NADPH] 1enzyme
DaunorubicinCarbonyl reductase [NADPH] 3enzyme
Beclomethasone dipropionateCorticosteroid-binding globulincarrier
Beclomethasone dipropionateGlucocorticoid receptortarget
Beclomethasone dipropionateCytochrome P450 3A5enzyme
Beclomethasone dipropionateCytochrome P450 3A4enzyme
Beclomethasone dipropionateP-glycoprotein 1transporter
Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
OxcarbazepineCytochrome P450 2C19enzyme
OxcarbazepineCytochrome P450 3A4enzyme
OxcarbazepineCytochrome P450 3A5enzyme
OxcarbazepineSerum albumincarrier
OxcarbazepineP-glycoprotein 1transporter
OxcarbazepineAldo-keto reductase family 1 member C1enzyme
OxcarbazepineAldo-keto reductase family 1 member C2enzyme
OxcarbazepineAldo-keto reductase family 1 member C3enzyme
OxcarbazepineAldo-keto reductase family 1 member C4enzyme
OxcarbazepineCarbonyl reductase [NADPH] 1enzyme
OxcarbazepineCarbonyl reductase [NADPH] 3enzyme
OxcarbazepineSodium channel proteintarget
ReserpineSynaptic vesicular amine transportertarget
ReserpineP-glycoprotein 1transporter
ReserpineSolute carrier family 22 member 1transporter
ReserpineBile salt export pumptransporter
ReserpineCanalicular multispecific organic anion transporter 1transporter
ReserpineSolute carrier family 22 member 2transporter
ReserpineCytochrome P450 3A5enzyme
ReserpineChromaffin granule amine transportertarget
ReserpineBaculoviral IAP repeat-containing protein 5target
ReserpineSolute carrier organic anion transporter family member 1B1transporter
ReserpineSolute carrier organic anion transporter family member 2B1transporter
ArmodafinilCytochrome P450 2C19enzyme
ArmodafinilCytochrome P450 3A4enzyme
ArmodafinilCytochrome P450 1A2enzyme
ArmodafinilCytochrome P450 2B6enzyme
ArmodafinilCytochrome P450 3A5enzyme
ArmodafinilCytochrome P450 2C9enzyme
ArmodafinilSodium-dependent dopamine transportertarget
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
FluticasoneCytochrome P450 3A4enzyme
FluticasoneCytochrome P450 2C8enzyme
FluticasoneP-glycoprotein 1carrier
FluticasoneSolute carrier organic anion transporter family member 1B1carrier
FluticasoneP-glycoprotein 1transporter
FluticasoneSolute carrier organic anion transporter family member 1B1transporter
FluticasoneGlucocorticoid receptortarget
FluticasoneCorticosteroid-binding globulincarrier
FluticasoneCytochrome P450 3A5enzyme
FluticasoneCytochrome P450 3A7enzyme
FluticasoneProgesterone receptortarget
FluticasoneCytosolic phospholipase A2target
FluticasoneMineralocorticoid receptortarget
Fluticasone furoateCytochrome P450 3A4enzyme
Fluticasone furoateGlucocorticoid receptortarget
Fluticasone furoateP-glycoprotein 1transporter
Fluticasone furoateCytochrome P450 2C8enzyme
Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
Fluticasone furoateCorticosteroid-binding globulincarrier
Fluticasone furoateCytochrome P450 3A5enzyme
Fluticasone furoateCytochrome P450 3A7enzyme
Fluticasone furoateProgesterone receptortarget
Fluticasone furoateMineralocorticoid receptortarget
Fluticasone furoateSerum albumincarrier
Fluticasone furoateAlpha-1-acid glycoprotein 1carrier
AmcinonideGlucocorticoid receptortarget
AmcinonideAnnexin A1target
AmcinonideCytochrome P450 3A4enzyme
AmcinonideCytochrome P450 3A5enzyme
Betamethasone phosphateCytochrome P450 3A4enzyme
Betamethasone phosphateCytochrome P450 3A5enzyme
Betamethasone phosphateGlucocorticoid receptortarget
Betamethasone phosphateAnnexin A1target
Betamethasone phosphateCorticosteroid-binding globulincarrier
Betamethasone phosphateSerum albumincarrier
Betamethasone phosphateSolute carrier organic anion transporter family member 1A2transporter
Betamethasone phosphateP-glycoprotein 1transporter
Betamethasone phosphateSolute carrier family 22 member 8transporter
ClobetasolCytochrome P450 3A4enzyme
ClobetasolCytochrome P450 3A5enzyme
Clobetasol propionateGlucocorticoid receptortarget
Clobetasol propionateCytochrome P450 3A4enzyme
Clobetasol propionateCytochrome P450 3A5enzyme
Clobetasol propionateAnnexin A1target
Clobetasol propionateMineralocorticoid receptortarget
Clobetasol propionateCorticosteroid-binding globulincarrier
Clobetasol propionateSerum albumincarrier
Clocortolone acetateCytochrome P450 3A4enzyme
Clocortolone acetateCytochrome P450 3A5enzyme
CloprednolCytochrome P450 3A4enzyme
CloprednolCytochrome P450 3A5enzyme
CortisoneCytochrome P450 3A4enzyme
CortisoneCytochrome P450 3A5enzyme
Cortisone acetateGlucocorticoid receptortarget
Cortisone acetateCytochrome P450 3A4enzyme
Cortisone acetateCytochrome P450 3A5enzyme
Cortisone acetateAnnexin A1target
Cortisone acetateCorticosteroid-binding globulincarrier
Cortisone acetateSerum albumincarrier
Cortisone acetateSolute carrier organic anion transporter family member 1A2transporter
Cortisone acetateP-glycoprotein 1transporter
Cortisone acetateSolute carrier family 22 member 8transporter
CortivazolGlucocorticoid receptortarget
CortivazolCytochrome P450 3A4enzyme
CortivazolCytochrome P450 3A5enzyme
DeflazacortCytochrome P450 3A4enzyme
DeflazacortGlucocorticoid receptortarget
DeflazacortCytochrome P450 3A5enzyme
Dexamethasone isonicotinateCytochrome P450 3A4enzyme
Dexamethasone isonicotinateCytochrome P450 3A5enzyme
DifluocortoloneAnnexin A3target
DifluocortoloneGlucocorticoid receptortarget
DifluocortoloneCytochrome P450 3A4enzyme
DifluocortoloneCytochrome P450 3A5enzyme
FluocinonideCorticosteroid-binding globulincarrier
FluocinonideGlucocorticoid receptortarget
FluocinonideSmoothened homologtarget
FluocinonideCytochrome P450 3A4enzyme
FluocinonideCytochrome P450 3A5enzyme
FluocortoloneCytochrome P450 3A4enzyme
FluocortoloneCytochrome P450 3A5enzyme
FluorometholoneCorticosteroid-binding globulincarrier
FluorometholoneCytochrome P450 3A4enzyme
FluorometholoneGlucocorticoid receptortarget
FluorometholoneCytochrome P450 3A5enzyme
FluprednideneCytochrome P450 3A4enzyme
FluprednideneCytochrome P450 3A5enzyme
Fluprednidene acetateCytochrome P450 3A4enzyme
Fluprednidene acetateCytochrome P450 3A5enzyme
HalometasoneCytochrome P450 3A4enzyme
HalometasoneCytochrome P450 3A5enzyme
MedrysoneCorticosteroid-binding globulincarrier
MedrysoneGlucocorticoid receptortarget
MedrysoneCytochrome P450 3A4enzyme
MedrysoneCytochrome P450 3A5enzyme
MedrysoneSolute carrier organic anion transporter family member 1A2transporter
MedrysoneP-glycoprotein 1transporter
MedrysoneSolute carrier family 22 member 8transporter
Melengestrol acetateCytochrome P450 3A4enzyme
Melengestrol acetateCytochrome P450 3A5enzyme
MeprednisoneSerum albumincarrier
MeprednisoneCytochrome P450 3A4enzyme
MeprednisoneCytochrome P450 3A5enzyme
Methylprednisolone hemisuccinateCytochrome P450 3A4enzyme
Methylprednisolone hemisuccinateCytochrome P450 3A5enzyme
MometasoneGlucocorticoid receptortarget
MometasoneCytochrome P450 2C8enzyme
MometasoneProgesterone receptortarget
MometasoneCytochrome P450 3A4enzyme
MometasoneCytochrome P450 3A5enzyme
Mometasone furoateGlucocorticoid receptortarget
Mometasone furoateCytochrome P450 2C8enzyme
Mometasone furoateProgesterone receptortarget
Mometasone furoateCytochrome P450 3A4enzyme
Mometasone furoateCytochrome P450 3A5enzyme
ParamethasoneCorticosteroid-binding globulincarrier
ParamethasoneGlucocorticoid receptortarget
ParamethasoneCytochrome P450 3A4enzyme
ParamethasoneCytochrome P450 3A5enzyme
Prednisolone hemisuccinateCytochrome P450 3A4enzyme
Prednisolone hemisuccinateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A4enzyme
Prednisolone phosphateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
Prednisolone phosphateCytochrome P450 2A6enzyme
Prednisolone phosphateCytochrome P450 1B1enzyme
Prednisolone phosphateCytochrome P450 2B6enzyme
Prednisolone phosphateCytochrome P450 2C8enzyme
Prednisolone phosphateCytochrome P450 2C9enzyme
Prednisolone phosphateCytochrome P450 2C19enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Prednisolone phosphateGlucocorticoid receptortarget
Prednisolone phosphateAnnexin A1target
Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
Prednisolone phosphateP-glycoprotein 1transporter
Prednisolone phosphateSolute carrier family 22 member 8transporter
Prednisolone phosphateCorticosteroid-binding globulincarrier
Prednisolone phosphateSerum albumincarrier
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Prednisone acetateCytochrome P450 3A4enzyme
Prednisone acetateCytochrome P450 3A5enzyme
PrednylideneCytochrome P450 3A4enzyme
PrednylideneCytochrome P450 3A5enzyme
RimexoloneCorticosteroid-binding globulincarrier
RimexoloneGlucocorticoid receptortarget
RimexoloneCytochrome P450 3A4enzyme
RimexoloneCytochrome P450 3A5enzyme
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
PralsetinibProto-oncogene tyrosine-protein kinase receptor Rettarget
PralsetinibEpithelial discoidin domain-containing receptor 1target
PralsetinibNT-3 growth factor receptortarget
PralsetinibReceptor-type tyrosine-protein kinase FLT3target
PralsetinibTyrosine-protein kinase JAK1target
PralsetinibTyrosine-protein kinase JAK2target
PralsetinibHigh affinity nerve growth factor receptortarget
PralsetinibVascular endothelial growth factor receptor 2target
PralsetinibPlatelet-derived growth factor receptor betatarget
PralsetinibFibroblast growth factor receptor 1target
PralsetinibFibroblast growth factor receptor 2target
PralsetinibCytochrome P450 3A4enzyme
PralsetinibCytochrome P450 3A5enzyme
PralsetinibCytochrome P450 2D6enzyme
PralsetinibCytochrome P450 1A2enzyme
PralsetinibCytochrome P450 2C8enzyme
PralsetinibCytochrome P450 2C9enzyme
PralsetinibP-glycoprotein 1transporter
PralsetinibATP-binding cassette sub-family G member 2transporter
PralsetinibSolute carrier organic anion transporter family member 1B1transporter
PralsetinibSolute carrier organic anion transporter family member 1B3transporter
PralsetinibSolute carrier family 22 member 6transporter
PralsetinibMultidrug and toxin extrusion protein 1transporter
PralsetinibMultidrug and toxin extrusion protein 2transporter
PralsetinibBile salt export pumptransporter
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideDNAtarget
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
ThalidomideCytochrome P450 3A4enzyme
ThalidomideCytochrome P450 1A1enzyme
ThalidomideCytochrome P450 2B6enzyme
LevoketoconazoleCytochrome P450 11B1, mitochondrialtarget
LevoketoconazoleLanosterol 14-alpha demethylasetarget
LevoketoconazoleCytochrome P450 3A4enzyme
LevoketoconazoleCytochrome P450 3A5enzyme
LevoketoconazoleSteroid 21-hydroxylaseenzyme
LevoketoconazoleP-glycoprotein 1transporter
LevoketoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
LevoketoconazoleCytochrome P450 11B2, mitochondrialtarget
LevoketoconazoleCholesterol side-chain cleavage enzyme, mitochondrialtarget
LevoketoconazoleSolute carrier family 22 member 2transporter
LevoketoconazoleMultidrug and toxin extrusion protein 1transporter
LevoketoconazoleCytochrome P450 2B6enzyme
LevoketoconazoleCytochrome P450 2C8enzyme
LevoketoconazoleCytochrome P450 1A2enzyme
LevoketoconazoleCytochrome P450 7A1enzyme
LevoketoconazoleCytochrome P450 19A1enzyme
OlaparibPoly [ADP-ribose] polymerase 1target
OlaparibCytochrome P450 3A4enzyme
OlaparibCytochrome P450 2B6enzyme
OlaparibPoly [ADP-ribose] polymerase 2target
OlaparibPoly [ADP-ribose] polymerase 3target
OlaparibCytochrome P450 3A5enzyme
OlaparibP-glycoprotein 1transporter
OlaparibATP-binding cassette sub-family G member 2transporter
OlaparibAldo-keto reductase family 1 member C3target
OlaparibUDP-glucuronosyltransferase 1-1enzyme
OlaparibSerum albumincarrier
OlaparibAlpha-1-acid glycoprotein 1carrier
CariprazineCytochrome P450 3A4enzyme
CariprazineCytochrome P450 2D6enzyme
CariprazineP-glycoprotein 1transporter
CariprazineCytochrome P450 3A5enzyme
CariprazineDopamine D3 receptortarget
CariprazineDopamine D2 receptortarget
Cariprazine5-hydroxytryptamine receptor 1Atarget
Cariprazine5-hydroxytryptamine receptor 2Btarget
Cariprazine5-hydroxytryptamine receptor 2Atarget
CariprazineHistamine H1 receptortarget
Cariprazine5-hydroxytryptamine receptor 2Ctarget
CariprazineAlpha-1A adrenergic receptortarget
CariprazineCytochrome P450 1A2enzyme
CariprazineCytochrome P450 2C9enzyme
CariprazineCytochrome P450 2C19enzyme
CariprazineCytochrome P450 2E1enzyme
PirtobrutinibCytochrome P450 3A4enzyme
PirtobrutinibUDP-glucuronosyltransferase 1-8enzyme
PirtobrutinibUDP-glucuronosyltransferase 1-9enzyme
PirtobrutinibCytochrome P450 2C8enzyme
PirtobrutinibCytochrome P450 2C9enzyme
PirtobrutinibCytochrome P450 1A2enzyme
PirtobrutinibCytochrome P450 2B6enzyme
PirtobrutinibCytochrome P450 2C19enzyme
PirtobrutinibCytochrome P450 2D6enzyme
PirtobrutinibCytochrome P450 3A5enzyme
PirtobrutinibTyrosine-protein kinase BTKtarget
PirtobrutinibP-glycoprotein 1transporter
PirtobrutinibATP-binding cassette sub-family G member 2transporter
TezacaftorCytochrome P450 3A4enzyme
TezacaftorCytochrome P450 3A5enzyme
TezacaftorCystic fibrosis transmembrane conductance regulatortarget
TezacaftorP-glycoprotein 1transporter
TezacaftorATP-binding cassette sub-family G member 2transporter
TezacaftorSolute carrier family 22 member 2transporter
TezacaftorSolute carrier family 22 member 6transporter
TezacaftorSolute carrier family 22 member 8transporter
TezacaftorSolute carrier organic anion transporter family member 1B1transporter
TezacaftorCytochrome P450 1A2enzyme
TezacaftorCytochrome P450 2B6enzyme
TezacaftorCytochrome P450 2C8enzyme
TezacaftorCytochrome P450 2C9enzyme
TezacaftorCytochrome P450 2C19enzyme
TezacaftorCytochrome P450 2D6enzyme
TezacaftorSolute carrier organic anion transporter family member 1B3transporter