OCT1 inhibitors

Name

OCT1 inhibitors

Accession Number

DBCAT004549

Description

Inhibitors of the OCT1 transporter

Drugs

Drug	Drug Description
Codeine	An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
Rocuronium	A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
Ganciclovir	A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
Acyclovir	A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
Dinoprostone	A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
Progesterone	A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
Prazosin	An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
Phenoxybenzamine	An alpha adrenergic antagonist used to treat pheochromocytoma and episodes of hypertension and sweating.
Phenformin	For the reatment of type II diabetes mellitus.
Procainamide	A medication used to treat life threatening ventricular arrhythmias.
Nicotine	A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
Choline	A nutrient found in a wide variety of vitamins including pre-natal formulations.
Verapamil	A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
Quinine	An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
Pancuronium	A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Cimetidine	A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
Disopyramide	A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
Desipramine	A tricyclic antidepressant used in the treatment of depression.
Guanidine	A strong organic base used to treat muscle weakness and fatigue associated with the myasthenic complications of Eaton-Lambert syndrome.
Probenecid	A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Saquinavir	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Chlorpheniramine	A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
Indinavir	A protease inhibitor used to treat HIV infection.
Reserpine	For the treatment of hypertension
Rucaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Estradiol acetate	An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
Estradiol benzoate	An estrogen indicated in combination with progesterone for the treatment of irregular menstruation.
Estradiol cypionate	An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
Estradiol dienanthate	An estrogen used in some combined hormonal oral contraceptives.
Estradiol valerate	An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
Pitolisant	An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.
Choline salicylate	The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
Quinidine	A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Amantadine	A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
Dexchlorpheniramine maleate	A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
Doxazosin	An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
Efavirenz	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
Nevirapine	A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
Clopidogrel	An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
Palbociclib	An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Linagliptin	A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
Nintedanib	A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
Dronedarone	An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
Lasmiditan	An oral 5HT1F agonist used for the acute treatment of migraine headache with or without aura.
Ranitidine	A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
Formoterol	An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
Guanfacine	An alpha-2A adrenergic receptor agonist used to treat ADHD.
Salmeterol	A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
Levofloxacin	A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
Osilodrostat	An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Lurbinectedin	A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer.
Tirbanibulin	A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
Cyproheptadine	A combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.
Infigratinib	An FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement.
Atogepant	An oral CGRP antagonist used for the preventative therapy of episodic migraine headaches.
Asciminib	An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Abrocitinib	A kinase inhibitor used to treat moderate-to-severe atopic dermatitis in adults.
Pacritinib	A kinase inhibitor used for the treatment of primary and secondary myelofibrosis in adult patients with significantly reduced platelet counts.
Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Tepotinib	An oral tyrosine kinase inhibitor targeted against MET for the treatment of metastatic non-small cell lung cancer in patients exhibiting MET exon 14 skipping mutations.
Palovarotene	A selective agonist of retinoic acid receptor gamma (RARγ) used to reduce heterotopic ossification in patients with Fibrodysplasia Ossificans Progressiva (FOP).

Drugs & Drug Targets

Drug	Target	Type
Codeine	Mu-type opioid receptor	target
Codeine	Delta-type opioid receptor	target
Codeine	Kappa-type opioid receptor	target
Codeine	Cytochrome P450 2D6	enzyme
Codeine	Cytochrome P450 3A4	enzyme
Codeine	Solute carrier family 22 member 1	transporter
Codeine	UDP-glucuronosyltransferase 2B7	enzyme
Codeine	UDP-glucuronosyltransferase 2B4	enzyme
Rocuronium	Neuronal acetylcholine receptor subunit alpha-2	target
Rocuronium	Muscarinic acetylcholine receptor M2	target
Rocuronium	5-hydroxytryptamine receptor 3A	target
Rocuronium	Solute carrier family 22 member 1	transporter
Rocuronium	Solute carrier organic anion transporter family member 1A2	transporter
Ganciclovir	DNA polymerase catalytic subunit	target
Ganciclovir	Solute carrier family 22 member 1	transporter
Ganciclovir	Solute carrier family 22 member 6	transporter
Ganciclovir	Solute carrier family 22 member 8	transporter
Ganciclovir	Solute carrier family 22 member 7	transporter
Ganciclovir	DNA	target
Ganciclovir	Multidrug and toxin extrusion protein 1	transporter
Ganciclovir	Multidrug and toxin extrusion protein 2	transporter
Ganciclovir	Thymidine kinase	target
Acyclovir	DNA polymerase catalytic subunit	target
Acyclovir	DNA polymerase catalytic subunit	target
Acyclovir	Solute carrier family 22 member 1	transporter
Acyclovir	Solute carrier family 22 member 6	transporter
Acyclovir	Solute carrier family 22 member 8	transporter
Acyclovir	Ileal sodium/bile acid cotransporter	transporter
Acyclovir	Multidrug and toxin extrusion protein 1	transporter
Acyclovir	Multidrug and toxin extrusion protein 2	transporter
Acyclovir	Thymidine kinase	enzyme
Acyclovir	Guanylate kinase	enzyme
Acyclovir	Nucleoside diphosphokinase	enzyme
Acyclovir	Pyruvate Kinases	enzyme
Acyclovir	Creatine Kinases	enzyme
Acyclovir	Phosphoglycerate Kinases	enzyme
Acyclovir	Succinyl-CoA Synthetases	enzyme
Acyclovir	Phosphoenolpyruvate Carboxykinases	enzyme
Acyclovir	Adenylosuccinate Synthetases	enzyme
Acyclovir	Serum albumin	carrier
Dinoprostone	Prostaglandin E2 receptor EP2 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP1 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP4 subtype	target
Dinoprostone	Prostaglandin E2 receptor EP3 subtype	target
Dinoprostone	Solute carrier family 22 member 2	transporter
Dinoprostone	Multidrug resistance-associated protein 5	transporter
Dinoprostone	Solute carrier family 22 member 6	transporter
Dinoprostone	Solute carrier family 22 member 8	transporter
Dinoprostone	Solute carrier family 22 member 11	transporter
Dinoprostone	Solute carrier family 22 member 7	transporter
Dinoprostone	Multidrug resistance-associated protein 4	transporter
Dinoprostone	Solute carrier organic anion transporter family member 2B1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1A2	transporter
Dinoprostone	Organic solute transporter subunit alpha	transporter
Dinoprostone	Organic solute transporter subunit beta	transporter
Dinoprostone	Solute carrier organic anion transporter family member 2A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 4A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1C1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 3A1	transporter
Dinoprostone	Solute carrier organic anion transporter family member 1B1	transporter
Dinoprostone	Prostaglandin D2 receptor 2	target
Progesterone	Progesterone receptor	target
Progesterone	Estrogen receptor alpha	target
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Progesterone	Cytochrome P450 2C19	enzyme
Progesterone	Cytochrome P450 2C9	enzyme
Progesterone	Cytochrome P450 3A4	enzyme
Progesterone	Cytochrome P450 3A5	enzyme
Progesterone	Cytochrome P450 3A7	enzyme
Progesterone	P-glycoprotein 1	transporter
Progesterone	Solute carrier family 22 member 2	transporter
Progesterone	Solute carrier family 22 member 1	transporter
Progesterone	Solute carrier family 22 member 3	transporter
Progesterone	Bile salt export pump	transporter
Progesterone	Multidrug resistance-associated protein 1	transporter
Progesterone	Sodium/bile acid cotransporter	transporter
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Progesterone	Cytochrome P450 1A1	enzyme
Progesterone	Cytochrome P450 1B1	enzyme
Progesterone	Cytochrome P450 2A6	enzyme
Progesterone	Cytochrome P450 2D6	enzyme
Progesterone	Mineralocorticoid receptor	target
Progesterone	Kappa-type opioid receptor	target
Progesterone	Alpha-1-acid glycoprotein 1	target
Progesterone	Glucocorticoid receptor	target
Progesterone	Androgen receptor	target
Progesterone	Sex hormone-binding globulin	target
Progesterone	Solute carrier organic anion transporter family member 1B1	transporter
Progesterone	ATP-binding cassette sub-family G member 2	transporter
Progesterone	Estrogen receptor beta	target
Progesterone	Solute carrier organic anion transporter family member 1B3	transporter
Prazosin	Alpha-1A adrenergic receptor	target
Prazosin	Alpha-1B adrenergic receptor	target
Prazosin	Alpha-1D adrenergic receptor	target
Prazosin	Potassium voltage-gated channel subfamily H member 2	target
Prazosin	Alpha-1-acid glycoprotein 1	carrier
Prazosin	Solute carrier family 22 member 1	transporter
Prazosin	Solute carrier family 22 member 3	transporter
Prazosin	P-glycoprotein 1	transporter
Prazosin	ATP-binding cassette sub-family G member 2	transporter
Prazosin	Alpha-2A adrenergic receptor	target
Prazosin	Alpha-2B adrenergic receptor	target
Prazosin	Alpha-1 adrenergic receptors	target
Phenoxybenzamine	Alpha-1A adrenergic receptor	target
Phenoxybenzamine	Calmodulin	target
Phenoxybenzamine	Solute carrier family 22 member 2	transporter
Phenoxybenzamine	Solute carrier family 22 member 1	transporter
Phenoxybenzamine	Solute carrier family 22 member 3	transporter
Phenoxybenzamine	Alpha-2A adrenergic receptor	target
Phenoxybenzamine	Alpha-2C adrenergic receptor	target
Phenoxybenzamine	Alpha-2B adrenergic receptor	target
Phenoxybenzamine	Beta-2 adrenergic receptor	target
Phenoxybenzamine	Alpha-1B adrenergic receptor	target
Phenoxybenzamine	Alpha-1D adrenergic receptor	target
Phenformin	5'-AMP-activated protein kinase catalytic subunit alpha-1	target
Phenformin	Cytochrome P450 2D6	enzyme
Phenformin	Solute carrier family 22 member 2	transporter
Phenformin	Solute carrier family 22 member 1	transporter
Phenformin	ATP-sensitive inward rectifier potassium channel 8	target
Procainamide	Sodium channel protein type 5 subunit alpha	target
Procainamide	DNA (cytosine-5)-methyltransferase 1	target
Procainamide	Cytochrome P450 2D6	enzyme
Procainamide	Cholinesterase	enzyme
Procainamide	Solute carrier family 22 member 2	transporter
Procainamide	Solute carrier family 22 member 1	transporter
Procainamide	Solute carrier family 22 member 3	transporter
Procainamide	Solute carrier family 22 member 5	transporter
Procainamide	Solute carrier family 22 member 4	transporter
Procainamide	Potassium voltage-gated channel subfamily H member 2	target
Procainamide	Multidrug and toxin extrusion protein 1	transporter
Procainamide	Multidrug and toxin extrusion protein 2	transporter
Nicotine	Neuronal acetylcholine receptor subunit alpha-2	target
Nicotine	Neuronal acetylcholine receptor subunit beta-2	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-7	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-4	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-10	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-9	target
Nicotine	Cytochrome P450 2A6	enzyme
Nicotine	Cytochrome P450 2E1	enzyme
Nicotine	Cytochrome P450 2A13	enzyme
Nicotine	Cytochrome P450 2B6	enzyme
Nicotine	Neuronal acetylcholine receptor subunit beta-4	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-3	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-5	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-6	target
Nicotine	Neuronal acetylcholine receptor subunit beta-3	target
Nicotine	Solute carrier family 22 member 2	transporter
Nicotine	Solute carrier family 22 member 1	transporter
Nicotine	Solute carrier family 22 member 3	transporter
Nicotine	Solute carrier family 22 member 5	transporter
Nicotine	Solute carrier family 22 member 4	transporter
Nicotine	Cytochrome P450 1A1	enzyme
Nicotine	Cytochrome P450 1A2	enzyme
Nicotine	Cytochrome P450 2C19	enzyme
Nicotine	Cytochrome P450 2C8	enzyme
Nicotine	Cytochrome P450 2C9	enzyme
Nicotine	Cytochrome P450 2D6	enzyme
Nicotine	Cytochrome P450 3A4	enzyme
Nicotine	Amine oxidase [flavin-containing] A	enzyme
Nicotine	Amine oxidase [flavin-containing] B	enzyme
Nicotine	Cytochrome P450 19A1	target
Nicotine	Choline O-acetyltransferase	target
Choline	Choline-phosphate cytidylyltransferase B	target
Choline	Acetylcholinesterase	target
Choline	Choline-phosphate cytidylyltransferase A	target
Choline	Phospholipase D2	target
Choline	Cholinesterase	target
Choline	Phospholipase D1	target
Choline	Phosphoethanolamine/phosphocholine phosphatase	target
Choline	Solute carrier family 22 member 2	transporter
Choline	Solute carrier family 22 member 1	transporter
Choline	Solute carrier family 22 member 3	transporter
Choline	Solute carrier family 22 member 5	transporter
Choline	Solute carrier family 22 member 4	transporter
Choline	Choline/ethanolaminephosphotransferase 1	enzyme
Choline	Choline transporter-like protein 1	transporter
Choline	Choline transporter-like protein 4	transporter
Choline	Choline transporter-like protein 2	transporter
Choline	Choline transporter-like protein 3	transporter
Choline	Choline/ethanolamine kinase	enzyme
Choline	Choline O-acetyltransferase	enzyme
Choline	Choline kinase alpha	enzyme
Choline	Choline dehydrogenase, mitochondrial	enzyme
Choline	High affinity choline transporter 1	transporter
Choline	Neuronal acetylcholine receptor subunit alpha-7	target
Verapamil	ATP-sensitive inward rectifier potassium channel 11	target
Verapamil	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Verapamil	Potassium voltage-gated channel subfamily H member 2	target
Verapamil	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Verapamil	Cytochrome P450 1A2	enzyme
Verapamil	Cytochrome P450 3A5	enzyme
Verapamil	Voltage-dependent N-type calcium channel subunit alpha-1B	target
Verapamil	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	target
Verapamil	Sodium-dependent serotonin transporter	target
Verapamil	Cytochrome P450 3A4	enzyme
Verapamil	P-glycoprotein 1	transporter
Verapamil	Solute carrier family 22 member 1	transporter
Verapamil	Canalicular multispecific organic anion transporter 2	transporter
Verapamil	Multidrug resistance-associated protein 4	transporter
Verapamil	Solute carrier family 22 member 5	transporter
Verapamil	Solute carrier organic anion transporter family member 1A2	transporter
Verapamil	Multidrug resistance-associated protein 7	transporter
Verapamil	Solute carrier family 22 member 4	transporter
Verapamil	Solute carrier organic anion transporter family member 1B1	transporter
Verapamil	Cytochrome P450 2C8	enzyme
Verapamil	Cytochrome P450 2C9	enzyme
Verapamil	Cytochrome P450 2B6	enzyme
Verapamil	Cytochrome P450 2C19	enzyme
Verapamil	Cytochrome P450 2D6	enzyme
Verapamil	Alpha-1A adrenergic receptor	target
Verapamil	Alpha-1B adrenergic receptor	target
Verapamil	Alpha-1D adrenergic receptor	target
Verapamil	Serum albumin	carrier
Verapamil	Alpha-1-acid glycoprotein 1	carrier
Verapamil	Cytochrome P450 2C18	enzyme
Verapamil	Cytochrome P450 2E1	enzyme
Verapamil	Multidrug resistance-associated protein 1	transporter
Verapamil	Multidrug and toxin extrusion protein 1	transporter
Verapamil	Multidrug and toxin extrusion protein 2	transporter
Verapamil	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Verapamil	Voltage-dependent calcium channel	target
Verapamil	P-glycoprotein 1	target
Quinine	Platelet glycoprotein IX	target
Quinine	Intermediate conductance calcium-activated potassium channel protein 4	target
Quinine	Cytochrome P450 3A4	enzyme
Quinine	Cytochrome P450 3A5	enzyme
Quinine	Cytochrome P450 1A1	enzyme
Quinine	Cytochrome P450 2D6	enzyme
Quinine	Cytochrome P450 1A2	enzyme
Quinine	Cytochrome P450 2C8	enzyme
Quinine	Cytochrome P450 2C9	enzyme
Quinine	Cytochrome P450 2C19	enzyme
Quinine	Cytochrome P450 2E1	enzyme
Quinine	Cytochrome P450 3A7	enzyme
Quinine	Solute carrier family 22 member 2	transporter
Quinine	Solute carrier family 22 member 1	transporter
Quinine	Solute carrier family 22 member 5	transporter
Quinine	P-glycoprotein 1	transporter
Quinine	Solute carrier organic anion transporter family member 1A2	transporter
Quinine	Solute carrier family 22 member 4	transporter
Quinine	Fe(II)-protoporphyrin IX	target
Quinine	Solute carrier organic anion transporter family member 1B1	transporter
Pancuronium	Neuronal acetylcholine receptor subunit alpha-2	target
Pancuronium	Cholinesterase	enzyme
Pancuronium	Muscarinic acetylcholine receptor M2	target
Pancuronium	Muscarinic acetylcholine receptor M3	target
Pancuronium	Solute carrier family 22 member 1	transporter
Pancuronium	Solute carrier family 22 member 2	transporter
Cimetidine	Histamine H2 receptor	target
Cimetidine	Cytochrome P450 1A2	enzyme
Cimetidine	Cytochrome P450 2D6	enzyme
Cimetidine	Cytochrome P450 2C19	enzyme
Cimetidine	Cytochrome P450 3A4	enzyme
Cimetidine	Cytochrome P450 3A5	enzyme
Cimetidine	P-glycoprotein 1	transporter
Cimetidine	Solute carrier family 22 member 2	transporter
Cimetidine	Solute carrier family 22 member 1	transporter
Cimetidine	Solute carrier family 22 member 3	transporter
Cimetidine	Solute carrier family 22 member 5	transporter
Cimetidine	Solute carrier family 22 member 6	transporter
Cimetidine	Solute carrier family 22 member 8	transporter
Cimetidine	Multidrug and toxin extrusion protein 1	transporter
Cimetidine	Solute carrier family 22 member 4	transporter
Cimetidine	Solute carrier family 22 member 11	transporter
Cimetidine	Solute carrier family 22 member 7	transporter
Cimetidine	Cytochrome P450 11B1, mitochondrial	enzyme
Cimetidine	Cytochrome P450 2C8	enzyme
Cimetidine	Cytochrome P450 2C9	enzyme
Cimetidine	Cytochrome P450 2E1	enzyme
Cimetidine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Cimetidine	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Cimetidine	Bile salt export pump	transporter
Cimetidine	Multidrug and toxin extrusion protein 2	transporter
Cimetidine	Serum albumin	carrier
Disopyramide	Sodium channel protein type 5 subunit alpha	target
Disopyramide	Alpha-1-acid glycoprotein 1	carrier
Disopyramide	Cytochrome P450 3A4	enzyme
Disopyramide	Muscarinic acetylcholine receptor M1	target
Disopyramide	Muscarinic acetylcholine receptor M2	target
Disopyramide	Muscarinic acetylcholine receptor M3	target
Disopyramide	Potassium voltage-gated channel subfamily D member 2	target
Disopyramide	Potassium voltage-gated channel subfamily D member 3	target
Disopyramide	Solute carrier family 22 member 2	transporter
Disopyramide	Solute carrier family 22 member 1	transporter
Disopyramide	Potassium voltage-gated channel subfamily H member 2	target
Disopyramide	Alpha-1-acid glycoprotein 2	target
Disopyramide	Cytochrome P450 1A2	enzyme
Desipramine	Muscarinic acetylcholine receptor M1	target
Desipramine	Sodium-dependent noradrenaline transporter	target
Desipramine	Beta-2 adrenergic receptor	target
Desipramine	Muscarinic acetylcholine receptor M2	target
Desipramine	Sodium-dependent serotonin transporter	target
Desipramine	Histamine H1 receptor	target
Desipramine	Beta-1 adrenergic receptor	target
Desipramine	Cytochrome P450 2D6	enzyme
Desipramine	Muscarinic acetylcholine receptor M3	target
Desipramine	Muscarinic acetylcholine receptor M4	target
Desipramine	Muscarinic acetylcholine receptor M5	target
Desipramine	Alpha-1 adrenergic receptors	target
Desipramine	5-hydroxytryptamine receptor 2A	target
Desipramine	Alpha-1-acid glycoprotein 1	carrier
Desipramine	Cytochrome P450 2B6	enzyme
Desipramine	Cytochrome P450 3A4	enzyme
Desipramine	Solute carrier family 22 member 2	transporter
Desipramine	Solute carrier family 22 member 1	transporter
Desipramine	Solute carrier family 22 member 3	transporter
Desipramine	Solute carrier family 22 member 5	transporter
Desipramine	P-glycoprotein 1	transporter
Desipramine	Solute carrier family 22 member 4	transporter
Desipramine	Cytochrome P450 1A2	enzyme
Desipramine	Cytochrome P450 2E1	enzyme
Desipramine	Sphingomyelin phosphodiesterase	target
Desipramine	5-hydroxytryptamine receptor 1A	target
Desipramine	5-hydroxytryptamine receptor 2C	target
Desipramine	Dopamine D2 receptor	target
Desipramine	Alpha-2 adrenergic receptors	target
Guanidine	Ribonuclease pancreatic	target
Guanidine	DNA	target
Guanidine	Disks large homolog 4	target
Guanidine	Lysozyme	target
Guanidine	Aldehyde dehydrogenase, mitochondrial	target
Guanidine	Guanidinoacetate N-methyltransferase	target
Guanidine	Arginase	target
Guanidine	Solute carrier family 22 member 2	transporter
Guanidine	Solute carrier family 22 member 1	transporter
Guanidine	Solute carrier family 22 member 3	transporter
Guanidine	Solute carrier family 22 member 5	transporter
Guanidine	Solute carrier family 22 member 8	transporter
Guanidine	Solute carrier family 22 member 4	transporter
Guanidine	Multidrug and toxin extrusion protein 1	transporter
Guanidine	Multidrug and toxin extrusion protein 2	transporter
Probenecid	Solute carrier family 22 member 8	target
Probenecid	Solute carrier family 22 member 11	target
Probenecid	Serum albumin	carrier
Probenecid	Solute carrier family 22 member 2	transporter
Probenecid	Solute carrier family 22 member 1	transporter
Probenecid	Canalicular multispecific organic anion transporter 2	transporter
Probenecid	Multidrug resistance-associated protein 4	transporter
Probenecid	Multidrug resistance-associated protein 5	transporter
Probenecid	Monocarboxylate transporter 2	transporter
Probenecid	Solute carrier family 22 member 5	transporter
Probenecid	Multidrug resistance-associated protein 6	transporter
Probenecid	Multidrug resistance-associated protein 1	transporter
Probenecid	Solute carrier organic anion transporter family member 1A2	transporter
Probenecid	Monocarboxylate transporter 1	transporter
Probenecid	Sodium/bile acid cotransporter	transporter
Probenecid	Solute carrier family 22 member 6	transporter
Probenecid	Solute carrier family 22 member 10	transporter
Probenecid	Solute carrier family 22 member 8	transporter
Probenecid	Canalicular multispecific organic anion transporter 1	transporter
Probenecid	ATP-binding cassette sub-family C member 11	transporter
Probenecid	Solute carrier family 22 member 11	transporter
Probenecid	Solute carrier organic anion transporter family member 1C1	transporter
Probenecid	Solute carrier family 22 member 7	transporter
Probenecid	Solute carrier family 22 member 6	target
Probenecid	Pannexin-1	target
Probenecid	Cytochrome P450 2C8	enzyme
Probenecid	Cytochrome P450 3A4	enzyme
Probenecid	Solute carrier family 22 member 12	transporter
Probenecid	Solute carrier family 2, facilitated glucose transporter member 9	transporter
Probenecid	Taste receptor type 2 member 16	target
Probenecid	UDP-glucuronosyltransferase 1-1	enzyme
Probenecid	Cytochrome P450 2C9	enzyme
Saquinavir	Human immunodeficiency virus type 1 protease	target
Saquinavir	Cytochrome P450 3A4	enzyme
Saquinavir	Cytochrome P450 3A5	enzyme
Saquinavir	Alpha-1-acid glycoprotein 1	carrier
Saquinavir	Serum albumin	carrier
Saquinavir	Cytochrome P450 3A7	enzyme
Saquinavir	P-glycoprotein 1	transporter
Saquinavir	Solute carrier family 22 member 1	transporter
Saquinavir	Solute carrier organic anion transporter family member 1A2	transporter
Saquinavir	ATP-binding cassette sub-family G member 2	transporter
Saquinavir	Solute carrier organic anion transporter family member 1B1	transporter
Saquinavir	Multidrug resistance-associated protein 1	transporter
Saquinavir	Canalicular multispecific organic anion transporter 1	transporter
Saquinavir	Cytochrome P450 2C8	enzyme
Saquinavir	Cytochrome P450 2D6	enzyme
Saquinavir	Solute carrier organic anion transporter family member 2B1	transporter
Saquinavir	Bile salt export pump	transporter
Nelfinavir	HIV-1 protease	target
Nelfinavir	Cytochrome P450 2C19	enzyme
Nelfinavir	Cytochrome P450 3A4	enzyme
Nelfinavir	Cytochrome P450 2B6	enzyme
Nelfinavir	Cytochrome P450 3A5	enzyme
Nelfinavir	Cytochrome P450 3A7	enzyme
Nelfinavir	P-glycoprotein 1	transporter
Nelfinavir	Solute carrier family 22 member 1	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1A2	transporter
Nelfinavir	ATP-binding cassette sub-family G member 2	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1B1	transporter
Nelfinavir	Cytochrome P450 2D6	enzyme
Nelfinavir	Serum albumin	carrier
Nelfinavir	UDP-glucuronosyltransferase 1-1	enzyme
Nelfinavir	Solute carrier organic anion transporter family member 1B3	transporter
Nelfinavir	Solute carrier organic anion transporter family member 2B1	transporter
Nelfinavir	Bile salt export pump	transporter
Nelfinavir	Cytochrome P450 2C9	enzyme
Nelfinavir	Alpha-1-acid glycoprotein 1	carrier
Chlorpheniramine	Histamine H1 receptor	target
Chlorpheniramine	Cytochrome P450 3A4	enzyme
Chlorpheniramine	Cytochrome P450 2D6	enzyme
Chlorpheniramine	Sodium-dependent serotonin transporter	target
Chlorpheniramine	Sodium-dependent noradrenaline transporter	target
Chlorpheniramine	Sodium-dependent dopamine transporter	target
Chlorpheniramine	Cytochrome P450 3A5	enzyme
Chlorpheniramine	Cytochrome P450 3A7	enzyme
Chlorpheniramine	Solute carrier family 22 member 2	transporter
Chlorpheniramine	Solute carrier family 22 member 1	transporter
Indinavir	Human immunodeficiency virus type 1 protease	target
Indinavir	Cytochrome P450 3A4	enzyme
Indinavir	Cytochrome P450 3A5	enzyme
Indinavir	Cytochrome P450 3A7	enzyme
Indinavir	P-glycoprotein 1	transporter
Indinavir	Solute carrier family 22 member 1	transporter
Indinavir	Multidrug resistance-associated protein 1	transporter
Indinavir	Solute carrier organic anion transporter family member 1A2	transporter
Indinavir	Solute carrier organic anion transporter family member 1B1	transporter
Indinavir	Canalicular multispecific organic anion transporter 1	transporter
Indinavir	Cytochrome P450 2D6	enzyme
Indinavir	UDP-glucuronosyltransferase 1-1	enzyme
Indinavir	Solute carrier organic anion transporter family member 2B1	transporter
Indinavir	Bile salt export pump	transporter
Reserpine	Synaptic vesicular amine transporter	target
Reserpine	P-glycoprotein 1	transporter
Reserpine	Solute carrier family 22 member 1	transporter
Reserpine	Bile salt export pump	transporter
Reserpine	Canalicular multispecific organic anion transporter 1	transporter
Reserpine	Solute carrier family 22 member 2	transporter
Reserpine	Cytochrome P450 3A5	enzyme
Reserpine	Chromaffin granule amine transporter	target
Reserpine	Baculoviral IAP repeat-containing protein 5	target
Reserpine	Solute carrier organic anion transporter family member 1B1	transporter
Reserpine	Solute carrier organic anion transporter family member 2B1	transporter
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Poly [ADP-ribose] polymerase 3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	P-glycoprotein 1	transporter
Rucaparib	ATP-binding cassette sub-family G member 2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	Multidrug resistance-associated protein 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Solute carrier family 22 member 8	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol acetate	Estrogen receptor alpha	target
Estradiol acetate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol acetate	Sex hormone-binding globulin	carrier
Estradiol acetate	Estrogen receptor beta	target
Estradiol acetate	Cytochrome P450 1A2	enzyme
Estradiol acetate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol acetate	Serum albumin	carrier
Estradiol acetate	Fatty acid-binding protein, intestinal	carrier
Estradiol acetate	Cytochrome P450 3A4	enzyme
Estradiol acetate	Cytochrome P450 3A5	enzyme
Estradiol acetate	Cytochrome P450 3A7	enzyme
Estradiol acetate	Solute carrier family 22 member 2	transporter
Estradiol acetate	Solute carrier family 22 member 1	transporter
Estradiol acetate	Solute carrier family 22 member 3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol acetate	Multidrug resistance-associated protein 7	transporter
Estradiol acetate	Solute carrier family 22 member 11	transporter
Estradiol acetate	ATP-binding cassette sub-family G member 2	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol acetate	P-glycoprotein 1	transporter
Estradiol acetate	Cytochrome P450 1A1	enzyme
Estradiol acetate	Cytochrome P450 1B1	enzyme
Estradiol acetate	Cytochrome P450 2C19	enzyme
Estradiol acetate	Cytochrome P450 2C8	enzyme
Estradiol acetate	Cytochrome P450 2C9	enzyme
Estradiol acetate	Solute carrier family 22 member 8	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol acetate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol acetate	Nuclear receptor coactivator 2	target
Estradiol acetate	G-protein coupled estrogen receptor 1	target
Estradiol acetate	ATP synthase subunit a	target
Estradiol acetate	Beclin-1	target
Estradiol acetate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol acetate	Estrogen-related receptor gamma	target
Estradiol benzoate	Estrogen receptor alpha	target
Estradiol benzoate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol benzoate	Sex hormone-binding globulin	carrier
Estradiol benzoate	Estrogen receptor beta	target
Estradiol benzoate	Cytochrome P450 1A2	enzyme
Estradiol benzoate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol benzoate	Serum albumin	carrier
Estradiol benzoate	Fatty acid-binding protein, intestinal	carrier
Estradiol benzoate	Cytochrome P450 3A4	enzyme
Estradiol benzoate	Cytochrome P450 3A5	enzyme
Estradiol benzoate	Cytochrome P450 3A7	enzyme
Estradiol benzoate	Solute carrier family 22 member 2	transporter
Estradiol benzoate	Solute carrier family 22 member 1	transporter
Estradiol benzoate	Solute carrier family 22 member 3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol benzoate	Multidrug resistance-associated protein 7	transporter
Estradiol benzoate	Solute carrier family 22 member 11	transporter
Estradiol benzoate	ATP-binding cassette sub-family G member 2	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol benzoate	P-glycoprotein 1	transporter
Estradiol benzoate	Cytochrome P450 1A1	enzyme
Estradiol benzoate	Cytochrome P450 1B1	enzyme
Estradiol benzoate	Cytochrome P450 2C19	enzyme
Estradiol benzoate	Cytochrome P450 2C8	enzyme
Estradiol benzoate	Cytochrome P450 2C9	enzyme
Estradiol benzoate	Solute carrier family 22 member 8	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol benzoate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol benzoate	Nuclear receptor coactivator 2	target
Estradiol benzoate	G-protein coupled estrogen receptor 1	target
Estradiol benzoate	ATP synthase subunit a	target
Estradiol benzoate	Beclin-1	target
Estradiol benzoate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol benzoate	Estrogen-related receptor gamma	target
Estradiol cypionate	Estrogen receptor alpha	target
Estradiol cypionate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol cypionate	Sex hormone-binding globulin	carrier
Estradiol cypionate	Estrogen receptor beta	target
Estradiol cypionate	Cytochrome P450 1A2	enzyme
Estradiol cypionate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol cypionate	Serum albumin	carrier
Estradiol cypionate	Fatty acid-binding protein, intestinal	carrier
Estradiol cypionate	Cytochrome P450 3A4	enzyme
Estradiol cypionate	Cytochrome P450 3A5	enzyme
Estradiol cypionate	Cytochrome P450 3A7	enzyme
Estradiol cypionate	Solute carrier family 22 member 2	transporter
Estradiol cypionate	Solute carrier family 22 member 1	transporter
Estradiol cypionate	Solute carrier family 22 member 3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol cypionate	Multidrug resistance-associated protein 7	transporter
Estradiol cypionate	Solute carrier family 22 member 11	transporter
Estradiol cypionate	ATP-binding cassette sub-family G member 2	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol cypionate	P-glycoprotein 1	transporter
Estradiol cypionate	Cytochrome P450 1A1	enzyme
Estradiol cypionate	Cytochrome P450 1B1	enzyme
Estradiol cypionate	Cytochrome P450 2C19	enzyme
Estradiol cypionate	Cytochrome P450 2C8	enzyme
Estradiol cypionate	Cytochrome P450 2C9	enzyme
Estradiol cypionate	Solute carrier family 22 member 8	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol cypionate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol cypionate	Nuclear receptor coactivator 2	target
Estradiol cypionate	G-protein coupled estrogen receptor 1	target
Estradiol cypionate	ATP synthase subunit a	target
Estradiol cypionate	Beclin-1	target
Estradiol cypionate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol cypionate	Estrogen-related receptor gamma	target
Estradiol dienanthate	Estrogen receptor alpha	target
Estradiol dienanthate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol dienanthate	Sex hormone-binding globulin	carrier
Estradiol dienanthate	Estrogen receptor beta	target
Estradiol dienanthate	Cytochrome P450 1A2	enzyme
Estradiol dienanthate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol dienanthate	Serum albumin	carrier
Estradiol dienanthate	Fatty acid-binding protein, intestinal	carrier
Estradiol dienanthate	Cytochrome P450 3A4	enzyme
Estradiol dienanthate	Cytochrome P450 3A5	enzyme
Estradiol dienanthate	Cytochrome P450 3A7	enzyme
Estradiol dienanthate	Solute carrier family 22 member 2	transporter
Estradiol dienanthate	Solute carrier family 22 member 1	transporter
Estradiol dienanthate	Solute carrier family 22 member 3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol dienanthate	Multidrug resistance-associated protein 7	transporter
Estradiol dienanthate	Solute carrier family 22 member 11	transporter
Estradiol dienanthate	ATP-binding cassette sub-family G member 2	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol dienanthate	P-glycoprotein 1	transporter
Estradiol dienanthate	Cytochrome P450 1A1	enzyme
Estradiol dienanthate	Cytochrome P450 1B1	enzyme
Estradiol dienanthate	Cytochrome P450 2C19	enzyme
Estradiol dienanthate	Cytochrome P450 2C8	enzyme
Estradiol dienanthate	Cytochrome P450 2C9	enzyme
Estradiol dienanthate	Solute carrier family 22 member 8	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol dienanthate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol dienanthate	Nuclear receptor coactivator 2	target
Estradiol dienanthate	G-protein coupled estrogen receptor 1	target
Estradiol dienanthate	ATP synthase subunit a	target
Estradiol dienanthate	Beclin-1	target
Estradiol dienanthate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol dienanthate	Estrogen-related receptor gamma	target
Estradiol valerate	Estrogen receptor alpha	target
Estradiol valerate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol valerate	Sex hormone-binding globulin	carrier
Estradiol valerate	Estrogen receptor beta	target
Estradiol valerate	Cytochrome P450 1A2	enzyme
Estradiol valerate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol valerate	Serum albumin	carrier
Estradiol valerate	Fatty acid-binding protein, intestinal	carrier
Estradiol valerate	Cytochrome P450 3A4	enzyme
Estradiol valerate	Cytochrome P450 3A5	enzyme
Estradiol valerate	Cytochrome P450 3A7	enzyme
Estradiol valerate	Solute carrier family 22 member 2	transporter
Estradiol valerate	Solute carrier family 22 member 1	transporter
Estradiol valerate	Solute carrier family 22 member 3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol valerate	Multidrug resistance-associated protein 7	transporter
Estradiol valerate	Solute carrier family 22 member 11	transporter
Estradiol valerate	ATP-binding cassette sub-family G member 2	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol valerate	P-glycoprotein 1	transporter
Estradiol valerate	Cytochrome P450 1A1	enzyme
Estradiol valerate	Cytochrome P450 1B1	enzyme
Estradiol valerate	Cytochrome P450 2C19	enzyme
Estradiol valerate	Cytochrome P450 2C8	enzyme
Estradiol valerate	Cytochrome P450 2C9	enzyme
Estradiol valerate	Solute carrier family 22 member 8	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol valerate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol valerate	Nuclear receptor coactivator 2	target
Estradiol valerate	G-protein coupled estrogen receptor 1	target
Estradiol valerate	ATP synthase subunit a	target
Estradiol valerate	Beclin-1	target
Estradiol valerate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol valerate	Estrogen-related receptor gamma	target
Pitolisant	Histamine H3 receptor	target
Pitolisant	Cytochrome P450 3A4	enzyme
Pitolisant	Cytochrome P450 2D6	enzyme
Pitolisant	Cytochrome P450 1A2	enzyme
Pitolisant	Cytochrome P450 2B6	enzyme
Pitolisant	Solute carrier family 22 member 1	transporter
Pitolisant	Potassium voltage-gated channel subfamily H member 2	target
Pitolisant	Serum albumin	carrier
Pitolisant	Alpha-1-acid glycoprotein 1	carrier
Choline salicylate	Choline-phosphate cytidylyltransferase B	target
Choline salicylate	Acetylcholinesterase	target
Choline salicylate	Choline-phosphate cytidylyltransferase A	target
Choline salicylate	Phospholipase D2	target
Choline salicylate	Cholinesterase	target
Choline salicylate	Phospholipase D1	target
Choline salicylate	Solute carrier family 22 member 2	transporter
Choline salicylate	Solute carrier family 22 member 1	transporter
Choline salicylate	Solute carrier family 22 member 3	transporter
Choline salicylate	Solute carrier family 22 member 5	transporter
Choline salicylate	Solute carrier family 22 member 4	transporter
Choline salicylate	Choline/ethanolaminephosphotransferase 1	enzyme
Choline salicylate	Choline transporter-like protein 1	transporter
Choline salicylate	Choline transporter-like protein 4	transporter
Choline salicylate	Choline transporter-like protein 3	transporter
Choline salicylate	Choline/ethanolamine kinase	enzyme
Choline salicylate	Choline O-acetyltransferase	enzyme
Choline salicylate	Choline kinase alpha	enzyme
Choline salicylate	Choline dehydrogenase, mitochondrial	enzyme
Choline salicylate	High affinity choline transporter 1	transporter
Choline salicylate	Neuronal acetylcholine receptor subunit alpha-7	target
Quinidine	Sodium channel protein type 5 subunit alpha	target
Quinidine	Alpha-1-acid glycoprotein 1	carrier
Quinidine	Potassium voltage-gated channel subfamily H member 2	target
Quinidine	Potassium channel subfamily K member 1	target
Quinidine	Potassium channel subfamily K member 6	target
Quinidine	Cytochrome P450 1A2	enzyme
Quinidine	Cytochrome P450 2E1	enzyme
Quinidine	Cytochrome P450 1A1	enzyme
Quinidine	Cytochrome P450 2D6	enzyme
Quinidine	Cytochrome P450 3A4	enzyme
Quinidine	Cytochrome P450 3A7	enzyme
Quinidine	Solute carrier family 22 member 2	transporter
Quinidine	Solute carrier family 22 member 1	transporter
Quinidine	Solute carrier family 22 member 5	transporter
Quinidine	P-glycoprotein 1	transporter
Quinidine	Solute carrier organic anion transporter family member 1A2	transporter
Quinidine	Solute carrier family 22 member 8	transporter
Quinidine	Canalicular multispecific organic anion transporter 1	transporter
Quinidine	Solute carrier family 22 member 4	transporter
Quinidine	Solute carrier organic anion transporter family member 1B1	transporter
Quinidine	Cytochrome P450 2B6	enzyme
Quinidine	Cytochrome P450 2C9	enzyme
Quinidine	Alpha-1A adrenergic receptor	target
Quinidine	Alpha-1B adrenergic receptor	target
Quinidine	Alpha-1D adrenergic receptor	target
Quinidine	Bile salt export pump	transporter
Quinidine	Cytochrome P450 2C8	enzyme
Quinidine	Serum albumin	carrier
Amantadine	Dopamine D2 receptor	target
Amantadine	Matrix protein 2	target
Amantadine	Aromatic-L-amino-acid decarboxylase	enzyme
Amantadine	Amine oxidase [flavin-containing] B	enzyme
Amantadine	Solute carrier family 22 member 2	transporter
Amantadine	Solute carrier family 22 member 1	transporter
Amantadine	Glutamate receptor ionotropic, NMDA 3A	target
Amantadine	Neuronal acetylcholine receptor subunit alpha-7	target
Amantadine	Neuronal acetylcholine receptor subunit alpha-4	target
Amantadine	Neuronal acetylcholine receptor subunit alpha-3	target
Dexchlorpheniramine maleate	Cytochrome P450 2D6	enzyme
Dexchlorpheniramine maleate	Histamine H1 receptor	target
Dexchlorpheniramine maleate	Solute carrier family 22 member 1	carrier
Dexchlorpheniramine maleate	Solute carrier family 22 member 2	carrier
Dexchlorpheniramine maleate	Cytochrome P450 3A4	enzyme
Doxazosin	Alpha-1A adrenergic receptor	target
Doxazosin	Alpha-1D adrenergic receptor	target
Doxazosin	HERG human cardiac K+ channel	target
Doxazosin	P-glycoprotein 1	transporter
Doxazosin	Cytochrome P450 2C19	enzyme
Doxazosin	Cytochrome P450 2D6	enzyme
Doxazosin	Solute carrier family 22 member 1	transporter
Doxazosin	Cytochrome P450 3A4	enzyme
Doxazosin	Alpha-1B adrenergic receptor	target
Doxazosin	Cytochrome P450 2C9	enzyme
Efavirenz	Cytochrome P450 2B6	enzyme
Efavirenz	Cytochrome P450 3A4	enzyme
Efavirenz	Cytochrome P450 2C19	enzyme
Efavirenz	Cytochrome P450 2C9	enzyme
Efavirenz	Cytochrome P450 1A2	enzyme
Efavirenz	Cytochrome P450 2D6	enzyme
Efavirenz	Reverse transcriptase/RNaseH	target
Efavirenz	Cytochrome P450 2C8	enzyme
Efavirenz	Serum albumin	carrier
Efavirenz	Cytochrome P450 3A5	enzyme
Efavirenz	Cytochrome P450 3A7	enzyme
Efavirenz	UDP-glucuronosyltransferase 1-1	enzyme
Efavirenz	Bile salt export pump	transporter
Efavirenz	Solute carrier family 22 member 1	transporter
Nevirapine	Cytochrome P450 3A4	enzyme
Nevirapine	Cytochrome P450 2B6	enzyme
Nevirapine	Cytochrome P450 3A5	enzyme
Nevirapine	Cytochrome P450 2C9	enzyme
Nevirapine	Cytochrome P450 2A6	enzyme
Nevirapine	Cytochrome P450 2D6	enzyme
Nevirapine	Reverse transcriptase/RNaseH	target
Nevirapine	Serum albumin	carrier
Nevirapine	Cytochrome P450 1A2	enzyme
Nevirapine	Solute carrier family 22 member 1	transporter
Nevirapine	Cytochrome P450 3A7	enzyme
Clopidogrel	P2Y purinoceptor 12	target
Clopidogrel	Cytochrome P450 3A4	enzyme
Clopidogrel	Cytochrome P450 2B6	enzyme
Clopidogrel	Cytochrome P450 3A5	enzyme
Clopidogrel	Cytochrome P450 2C19	enzyme
Clopidogrel	Cytochrome P450 2C9	enzyme
Clopidogrel	Cytochrome P450 1A2	enzyme
Clopidogrel	Cytochrome P450 2C8	enzyme
Clopidogrel	Liver carboxylesterase 1	enzyme
Clopidogrel	P-glycoprotein 1	transporter
Clopidogrel	Solute carrier family 22 member 1	transporter
Clopidogrel	Solute carrier family 22 member 2	transporter
Clopidogrel	Serum albumin	carrier
Dacomitinib	Cytochrome P450 2D6	enzyme
Dacomitinib	Serum albumin	carrier
Dacomitinib	Cytochrome P450 3A4	enzyme
Dacomitinib	Cytochrome P450 2C9	enzyme
Dacomitinib	UDP-glucuronosyltransferase 1-1	enzyme
Dacomitinib	P-glycoprotein 1	transporter
Dacomitinib	ATP-binding cassette sub-family G member 2	transporter
Dacomitinib	Solute carrier family 22 member 1	transporter
Dacomitinib	Epidermal growth factor receptor	target
Gilteritinib	Serum albumin	carrier
Gilteritinib	Cytochrome P450 3A4	enzyme
Gilteritinib	Receptor-type tyrosine-protein kinase FLT3	target
Gilteritinib	Serotonin Receptors	target
Gilteritinib	P-glycoprotein 1	transporter
Gilteritinib	Multidrug and toxin extrusion protein 1	transporter
Gilteritinib	ATP-binding cassette sub-family G member 2	transporter
Gilteritinib	Solute carrier family 22 member 1	transporter
Gilteritinib	Tyrosine-protein kinase receptor UFO	target
Gilteritinib	ALK tyrosine kinase receptor	target
Palbociclib	Cyclin-dependent kinase 4	target
Palbociclib	Cyclin-dependent kinase 6	target
Palbociclib	Cytochrome P450 3A4	enzyme
Palbociclib	Bile salt sulfotransferase	enzyme
Palbociclib	P-glycoprotein 1	transporter
Palbociclib	ATP-binding cassette sub-family G member 2	transporter
Palbociclib	Serum albumin	carrier
Palbociclib	Solute carrier family 22 member 1	transporter
Linagliptin	Dipeptidyl peptidase 4	target
Linagliptin	Cytochrome P450 3A4	enzyme
Linagliptin	P-glycoprotein 1	transporter
Linagliptin	Solute carrier family 22 member 1	transporter
Linagliptin	Solute carrier family 22 member 2	transporter
Linagliptin	Solute carrier family 22 member 3	transporter
Nintedanib	Vascular endothelial growth factor receptor 1	target
Nintedanib	Vascular endothelial growth factor receptor 2	target
Nintedanib	Vascular endothelial growth factor receptor 3	target
Nintedanib	Platelet-derived growth factor receptor alpha	target
Nintedanib	Platelet-derived growth factor receptor beta	target
Nintedanib	Fibroblast growth factor receptor 1	target
Nintedanib	Fibroblast growth factor receptor 2	target
Nintedanib	Fibroblast growth factor receptor 3	target
Nintedanib	Receptor-type tyrosine-protein kinase FLT3	target
Nintedanib	Tyrosine-protein kinase Lck	target
Nintedanib	Tyrosine-protein kinase Lyn	target
Nintedanib	Proto-oncogene tyrosine-protein kinase Src	target
Nintedanib	P-glycoprotein 1	transporter
Nintedanib	Cytochrome P450 3A4	enzyme
Nintedanib	Solute carrier family 22 member 1	transporter
Nintedanib	Serum albumin	carrier
Nintedanib	UDP-glucuronosyltransferase 1-1	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-7	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-8	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-10	enzyme
Nintedanib	ATP-binding cassette sub-family G member 2	transporter
Dronedarone	Alpha-1A adrenergic receptor	target
Dronedarone	Beta-1 adrenergic receptor	target
Dronedarone	Alpha-1B adrenergic receptor	target
Dronedarone	Alpha-1D adrenergic receptor	target
Dronedarone	Alpha-2A adrenergic receptor	target
Dronedarone	Alpha-2B adrenergic receptor	target
Dronedarone	Alpha-2C adrenergic receptor	target
Dronedarone	Potassium voltage-gated channel subfamily H member 2	target
Dronedarone	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Dronedarone	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Dronedarone	Voltage-dependent L-type calcium channel subunit alpha-1F	target
Dronedarone	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Dronedarone	Voltage-dependent L-type calcium channel subunit beta-1	target
Dronedarone	Voltage-dependent L-type calcium channel subunit beta-2	target
Dronedarone	Voltage-dependent L-type calcium channel subunit beta-3	target
Dronedarone	Voltage-dependent L-type calcium channel subunit beta-4	target
Dronedarone	Cytochrome P450 2D6	enzyme
Dronedarone	Cytochrome P450 3A4	enzyme
Dronedarone	P-glycoprotein 1	transporter
Dronedarone	Potassium channel subfamily K member 2	target
Dronedarone	Serum albumin	carrier
Dronedarone	Solute carrier family 22 member 2	transporter
Dronedarone	Solute carrier family 22 member 1	transporter
Dronedarone	Solute carrier organic anion transporter family member 1B1	transporter
Dronedarone	Solute carrier organic anion transporter family member 1B3	transporter
Dronedarone	Solute carrier family 22 member 8	transporter
Dronedarone	Cytochrome P450 3A5	enzyme
Dronedarone	Cytochrome P450 2J2	enzyme
Dronedarone	Thyroid hormone receptor alpha	target
Dronedarone	Sodium channel protein type 5 subunit alpha	target
Dronedarone	G protein-activated inward rectifier potassium channel 1	target
Dronedarone	Potassium voltage-gated channel subfamily KQT member 1	target
Dronedarone	Inward rectifier potassium channel	target
Dronedarone	Sodium/calcium exchanger 1	target
Dronedarone	Potassium voltage-gated channel subfamily D member 3	target
Lasmiditan	5-hydroxytryptamine receptor 1F	target
Lasmiditan	P-glycoprotein 1	transporter
Lasmiditan	ATP-binding cassette sub-family G member 2	transporter
Lasmiditan	Solute carrier family 22 member 1	transporter
Lasmiditan	Multidrug and toxin extrusion protein 1	transporter
Lasmiditan	Multidrug and toxin extrusion protein 2	transporter
Lasmiditan	Cytochrome P450 2D6	enzyme
Ranitidine	Histamine H2 receptor	target
Ranitidine	Cytochrome P450 1A2	enzyme
Ranitidine	Cytochrome P450 2D6	enzyme
Ranitidine	Solute carrier family 22 member 1	transporter
Ranitidine	P-glycoprotein 1	transporter
Ranitidine	Solute carrier family 22 member 8	transporter
Ranitidine	Cytochrome P450 3A4	enzyme
Ranitidine	Acetylcholinesterase	target
Ranitidine	Solute carrier family 22 member 2	transporter
Ranitidine	Acetylcholinesterase	enzyme
Formoterol	Beta-2 adrenergic receptor	target
Formoterol	Beta-1 adrenergic receptor	target
Formoterol	Beta-3 adrenergic receptor	target
Formoterol	Cytochrome P450 2D6	enzyme
Formoterol	Cytochrome P450 2C19	enzyme
Formoterol	Cytochrome P450 2C9	enzyme
Formoterol	Cytochrome P450 2A6	enzyme
Formoterol	UDP-glucuronosyltransferase 1A1	enzyme
Formoterol	UDP-glucuronosyltransferase 1-8	enzyme
Formoterol	UDP-glucuronosyltransferase 1-9	enzyme
Formoterol	UDP-glucuronosyltransferase 2B7	enzyme
Formoterol	UDP-glucuronosyltransferase 2B15	enzyme
Formoterol	Solute carrier family 22 member 1	transporter
Formoterol	Solute carrier family 22 member 4	transporter
Formoterol	Solute carrier family 22 member 5	transporter
Formoterol	Solute carrier family 22 member 3	transporter
Formoterol	Serum albumin	carrier
Guanfacine	Alpha-2A adrenergic receptor	target
Guanfacine	Cytochrome P450 2C19	enzyme
Guanfacine	Cytochrome P450 3A4	enzyme
Guanfacine	Alpha-2B adrenergic receptor	target
Guanfacine	Multidrug and toxin extrusion protein 1	transporter
Guanfacine	Solute carrier family 22 member 1	transporter
Guanfacine	Solute carrier family 22 member 2	transporter
Salmeterol	Beta-2 adrenergic receptor	target
Salmeterol	Cytochrome P450 3A4	enzyme
Salmeterol	Cytochrome P450 2C8	enzyme
Salmeterol	Cytochrome P450 3A5	enzyme
Salmeterol	Cytochrome P450 3A7	enzyme
Salmeterol	Beta-1 adrenergic receptor	target
Salmeterol	Beta-3 adrenergic receptor	target
Salmeterol	Serum albumin	carrier
Salmeterol	alpha1-acid glycoprotein	carrier
Salmeterol	Solute carrier family 22 member 1	transporter
Salmeterol	Solute carrier family 22 member 2	transporter
Salmeterol	Solute carrier family 22 member 3	transporter
Levofloxacin	DNA gyrase subunit A	target
Levofloxacin	DNA topoisomerase 4 subunit A	target
Levofloxacin	Solute carrier family 22 member 2	transporter
Levofloxacin	P-glycoprotein 1	transporter
Levofloxacin	Solute carrier family 22 member 4	transporter
Levofloxacin	Multidrug and toxin extrusion protein 1	transporter
Levofloxacin	Multidrug and toxin extrusion protein 2	transporter
Levofloxacin	Cytochrome P450 2C9	enzyme
Levofloxacin	Serum albumin	carrier
Levofloxacin	Solute carrier organic anion transporter family member 4C1	transporter
Levofloxacin	Solute carrier family 22 member 1	transporter
Levofloxacin	Solute carrier organic anion transporter family member 1A2	transporter
Osilodrostat	Cytochrome P450 11B1, mitochondrial	target
Osilodrostat	Cytochrome P450 11B2, mitochondrial	target
Osilodrostat	Cytochrome P450 3A4	enzyme
Osilodrostat	Cytochrome P450 2B6	enzyme
Osilodrostat	Cytochrome P450 2D6	enzyme
Osilodrostat	UDP-glucuronosyltransferase 1-4	enzyme
Osilodrostat	UDP-glucuronosyltransferase 2B7	enzyme
Osilodrostat	UDP-glucuronosyltransferase 2B10	enzyme
Osilodrostat	Cytochrome P450 3A5	enzyme
Osilodrostat	Cytochrome P450 1A2	enzyme
Osilodrostat	Cytochrome P450 2C19	enzyme
Osilodrostat	Cytochrome P450 2E1	enzyme
Osilodrostat	UDP-glucuronosyltransferase 1A1	enzyme
Osilodrostat	Solute carrier organic anion transporter family member 1B1	transporter
Osilodrostat	Solute carrier family 22 member 1	transporter
Osilodrostat	Solute carrier family 22 member 2	transporter
Osilodrostat	Solute carrier family 22 member 6	transporter
Osilodrostat	Solute carrier family 22 member 8	transporter
Osilodrostat	Multidrug and toxin extrusion protein 1	transporter
Lurbinectedin	Cytochrome P450 3A4	enzyme
Lurbinectedin	DNA	target
Lurbinectedin	Serum albumin	carrier
Lurbinectedin	Alpha-1-acid glycoprotein 1	carrier
Lurbinectedin	P-glycoprotein 1	transporter
Lurbinectedin	Solute carrier organic anion transporter family member 1B1	transporter
Lurbinectedin	Solute carrier organic anion transporter family member 1B3	transporter
Lurbinectedin	Solute carrier family 22 member 1	transporter
Tirbanibulin	Proto-oncogene tyrosine-protein kinase Src	target
Tirbanibulin	Tubulin beta chain	target
Tirbanibulin	Cytochrome P450 3A4	enzyme
Tirbanibulin	Cytochrome P450 2C8	enzyme
Tirbanibulin	Cytochrome P450 1A2	enzyme
Tirbanibulin	Cytochrome P450 2B6	enzyme
Tirbanibulin	Cytochrome P450 2C9	enzyme
Tirbanibulin	Cytochrome P450 2C19	enzyme
Tirbanibulin	Cytochrome P450 2D6	enzyme
Tirbanibulin	Multidrug and toxin extrusion protein 1	transporter
Tirbanibulin	Multidrug and toxin extrusion protein 2	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B1	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B3	transporter
Tirbanibulin	Solute carrier family 22 member 1	transporter
Tirbanibulin	Solute carrier family 22 member 2	transporter
Cyproheptadine	5-hydroxytryptamine receptor 2A	target
Cyproheptadine	Histamine H1 receptor	target
Cyproheptadine	Muscarinic acetylcholine receptor M1	target
Cyproheptadine	Muscarinic acetylcholine receptor M2	target
Cyproheptadine	Muscarinic acetylcholine receptor M3	target
Cyproheptadine	5-hydroxytryptamine receptor 2C	target
Cyproheptadine	UDP-glucuronosyltransferase 1-3	enzyme
Cyproheptadine	5-hydroxytryptamine receptor 7	target
Cyproheptadine	UDP-glucuronosyltransferase 2B10	enzyme
Cyproheptadine	UDP-glucuronosyltransferase 1-4	enzyme
Cyproheptadine	5-hydroxytryptamine receptor 2B	target
Cyproheptadine	Histamine H2 receptor	target
Cyproheptadine	Solute carrier family 22 member 1	transporter
Cyproheptadine	Serum albumin	carrier
Infigratinib	Cytochrome P450 3A4	enzyme
Infigratinib	Multidrug and toxin extrusion protein 1	transporter
Infigratinib	ATP-binding cassette sub-family G member 2	transporter
Infigratinib	Bile salt export pump	transporter
Infigratinib	Solute carrier family 22 member 1	transporter
Infigratinib	Solute carrier family 22 member 2	transporter
Infigratinib	Multidrug and toxin extrusion protein 2	transporter
Infigratinib	P-glycoprotein 1	transporter
Infigratinib	Solute carrier organic anion transporter family member 1B1	transporter
Infigratinib	Solute carrier organic anion transporter family member 1B3	transporter
Infigratinib	Apolipoproteins	carrier
Infigratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Infigratinib	Fibroblast growth factor receptor 1	target
Infigratinib	Fibroblast growth factor receptor 2	target
Infigratinib	Fibroblast growth factor receptor 3	target
Infigratinib	Fibroblast growth factor receptor 4	target
Atogepant	Calcitonin gene-related peptide type 1 receptor	target
Atogepant	Cytochrome P450 3A4	enzyme
Atogepant	Solute carrier organic anion transporter family member 1B1	transporter
Atogepant	Solute carrier organic anion transporter family member 1B3	transporter
Atogepant	Solute carrier family 22 member 6	transporter
Atogepant	ATP-binding cassette sub-family G member 2	transporter
Atogepant	P-glycoprotein 1	transporter
Atogepant	Solute carrier family 22 member 1	transporter
Atogepant	Multidrug and toxin extrusion protein 1	transporter
Asciminib	Cytochrome P450 3A4	enzyme
Asciminib	UDP-glucuronosyltransferase 2B7	enzyme
Asciminib	UDP-glucuronosyltransferase 2B17	enzyme
Asciminib	Tyrosine-protein kinase ABL1	target
Asciminib	ATP-binding cassette sub-family G member 2	transporter
Asciminib	UDP-glucuronosyltransferase 1-1	enzyme
Asciminib	Cytochrome P450 2C19	enzyme
Asciminib	P-glycoprotein 1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B3	transporter
Asciminib	Solute carrier family 22 member 1	transporter
Asciminib	Cytochrome P450 2C9	enzyme
Abrocitinib	Cytochrome P450 2C19	enzyme
Abrocitinib	Cytochrome P450 2C9	enzyme
Abrocitinib	Cytochrome P450 3A4	enzyme
Abrocitinib	Cytochrome P450 2B6	enzyme
Abrocitinib	Tyrosine-protein kinase JAK1	target
Abrocitinib	P-glycoprotein 1	transporter
Abrocitinib	Solute carrier family 22 member 1	transporter
Abrocitinib	Tyrosine-protein kinase JAK2	target
Abrocitinib	Tyrosine-protein kinase JAK3	target
Abrocitinib	Non-receptor tyrosine-protein kinase TYK2	target
Abrocitinib	Serum albumin	carrier
Abrocitinib	Solute carrier family 22 member 8	transporter
Pacritinib	Cytochrome P450 3A4	enzyme
Pacritinib	Cytochrome P450 1A2	enzyme
Pacritinib	Tyrosine-protein kinase JAK2	target
Pacritinib	Receptor-type tyrosine-protein kinase FLT3	target
Pacritinib	P-glycoprotein 1	transporter
Pacritinib	ATP-binding cassette sub-family G member 2	transporter
Pacritinib	Solute carrier family 22 member 1	transporter
Pacritinib	Cytochrome P450 2C19	enzyme
Pacritinib	Solute carrier family 22 member 2	transporter
Olaparib	Poly [ADP-ribose] polymerase 1	target
Olaparib	Cytochrome P450 3A4	enzyme
Olaparib	Cytochrome P450 2B6	enzyme
Olaparib	Poly [ADP-ribose] polymerase 2	target
Olaparib	Poly [ADP-ribose] polymerase 3	target
Olaparib	Cytochrome P450 3A5	enzyme
Olaparib	P-glycoprotein 1	transporter
Olaparib	ATP-binding cassette sub-family G member 2	transporter
Olaparib	Aldo-keto reductase family 1 member C3	target
Olaparib	UDP-glucuronosyltransferase 1-1	enzyme
Olaparib	Serum albumin	carrier
Olaparib	Alpha-1-acid glycoprotein 1	carrier
Tepotinib	P-glycoprotein 1	transporter
Tepotinib	Cytochrome P450 3A4	enzyme
Tepotinib	Cytochrome P450 2C8	enzyme
Tepotinib	ATP-binding cassette sub-family G member 2	transporter
Tepotinib	Hepatocyte growth factor receptor	target
Tepotinib	Nischarin	target
Tepotinib	Melatonin receptor type 1B	target
Tepotinib	Serum albumin	carrier
Tepotinib	Alpha-1-acid glycoprotein 1	carrier
Tepotinib	Solute carrier family 22 member 1	transporter
Tepotinib	Solute carrier family 22 member 2	transporter
Tepotinib	Multidrug and toxin extrusion protein 1	transporter
Tepotinib	Multidrug and toxin extrusion protein 2	transporter
Tepotinib	Bile salt export pump	transporter
Tepotinib	Cytochrome P450 2C9	enzyme
Palovarotene	Retinoic acid receptor gamma	target
Palovarotene	Cytochrome P450 3A4	enzyme
Palovarotene	Cytochrome P450 2C8	enzyme
Palovarotene	Cytochrome P450 2C19	enzyme
Palovarotene	ATP-binding cassette sub-family G member 2	transporter
Palovarotene	Solute carrier organic anion transporter family member 1B1	transporter
Palovarotene	Solute carrier organic anion transporter family member 1B3	transporter
Palovarotene	Solute carrier family 22 member 1	transporter
Palovarotene	Bile salt export pump	transporter
Palovarotene	Cytochrome P450 2B6	enzyme