Calcium-Regulating Hormones and Agents
- Name
- Calcium-Regulating Hormones and Agents
- Accession Number
- DBCAT004967
- Description
Hormones and molecules with calcium regulating hormone-like actions that modulate OSTEOLYSIS and other extra-skeletal activities to maintain calcium homeostasis.
- Drugs
Drug Drug Description Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Lamotrigine A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. Cinnarizine A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting. Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Calcium A mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency. Flunarizine A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. Gallium nitrate A drug previously indicated to treat cancer-related hypercalcemia. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Ziconotide An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. Elcatonin Not Annotated Lidoflazine Not Annotated Calcium citrate An ingredient found in a variety of supplements and vitamins. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Ergocalciferol A vitamin found in many supplement products. Cinacalcet A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Plicamycin For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Amlodipine A calcium channel blocker used to treat hypertension and angina. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Lercanidipine A calcium channel blocker for the management of hypertension. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Felodipine A calcium channel blocker used to treat hypertension. Nitrendipine A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension. Perhexiline For the management of severe angina pectoris. Bepridil For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). Mibefradil For the treatment of angina and high blood pressure. Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Azimilide Investigated for use/treatment in arrhythmia and atrial fibrillation. Dotarizine A calcium antagonist used to treat and prevent migraines. Nilvadipine A calcium channel blocker used to manage arterial hypertension. Tranilast For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. Fasudil Fasudil has been investigated in Carotid Stenosis. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Eperisone An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles. Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Tolfenamic acid In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. Barnidipine A calcium channel blocker used to treat various forms of hypertension. Benidipine A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. Cilnidipine A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension. Darodipine Darodipine is a calcium channel blocker. Efonidipine For the treatment of hypertension. Lacidipine A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. Manidipine A dihydropyridine calcium channel blocker used to treat hypertension. Niguldipine Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. Niludipine Niludipine is a calcium channel blocker. Carboxyamidotriazole Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. Naftopidil Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. Tetrahydropalmatine Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). Etripamil Etripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT). Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Bencyclane A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Terodiline Not Annotated Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. WIN 55212-2 WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... Dexverapamil Not Annotated Emopamil Prevents renal injury after warm & cold ischemia. Lomerizine Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated... Tetrandrine Not Annotated Dexniguldipine Not Annotated SOR-C13 SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel). Apinocaltamide Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients). Z-160 Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy. SKF-96365 free base SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists. 24,25-Dihydroxycholecalciferol Not Annotated Berbamine Not Annotated - Drugs & Drug Targets