Cytochrome P-450 Substrates

Accession Number

DBCAT005101

Description

Not Available

Drugs

Drug	Drug Description
Bortezomib	A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
Caffeine	A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
Anagrelide	A platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
Ropinirole	A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
Theophylline	A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
Lidocaine	A local anesthetic used in a wide variety of superficial and invasive procedures.
Conjugated estrogens	A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
Ropivacaine	An amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain.
Zolmitriptan	A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults.
Amitriptyline	A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
Olanzapine	An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
Clozapine	An atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
Grepafloxacin	A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
Mirtazapine	A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Mexiletine	A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
Tacrine	An anticholinesterase drug used for the management of Alzheimer's disease symptoms.
Imipramine	A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
Duloxetine	A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
Flutamide	An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
Haloperidol	An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
Nortriptyline	A tricyclic antidepressant used in the treatment of depression.
Fluorouracil	A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
Propranolol	A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
Estrone	An estrogen used to treat perimenopausal and postmenopausal symptoms.
Verapamil	A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
Warfarin	A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
Tizanidine	An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
Riluzole	A glutamate antagonist used to treat amyotrophic lateral sclerosis.
Zileuton	A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
Estradiol	An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
Dacarbazine	An antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
Ondansetron	A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
Cyclobenzaprine	A skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
Ramelteon	A melatonin receptor agonist used to treat insomnia.
Frovatriptan	A 5-HT1B/1D receptor agonist used to treat migraines.
Levobupivacaine	A drug used for nerve block and anesthesia.
Cinacalcet	A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
Pimozide	An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder.
Propafenone	A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
Clomipramine	A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.
Rasagiline	An irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
Chlorzoxazone	A drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
Chlorpromazine	A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
Mephenytoin	A phenylhydantoin used to treat refractory partial epilepsy.
Diclofenac	An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Azelastine	A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
Acenocoumarol	An anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.
Aminophenazone	An analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine.
Palonosetron	A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
Melatonin	An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
Imatinib	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
Quinine	An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
Doxepin	A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
Carbamazepine	An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
Zolpidem	A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
Fluoxetine	A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
Antipyrine	An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
Terbinafine	An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
Cinnarizine	A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting.
Flunarizine	A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
Naproxen	An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
Phenacetin	Used principally as an analgesic.
Aminophylline	A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
Asenapine	An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.
Betaxolol	A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Estrone sulfate	An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
Guanabenz	An alpha-2 adrenergic agonist used to treat hypertension.
Thiothixene	An antipsychotic indicated for the management of schizophrenia.
Trifluoperazine	A phenothiazine used to treat depression, anxiety, and agitation.
Promazine	A phenothiazine used to manage schizophrenia.
Carvedilol	A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
Genistein	Currently Genistein is being studied in clinical trials as a treatment for prostate cancer.
Resveratrol	Being investigated for the treatment of Herpes labialis infections (cold sores).
Albendazole	A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
Bromazepam	A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
Desipramine	A tricyclic antidepressant used in the treatment of depression.
Dexfenfluramine	For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
Domperidone	A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
Ethanol	For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
Etoposide	A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Lumiracoxib	For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
Malathion	A parasympathomimetic organophosphate used to treat head lice.
Maprotiline	A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
Methadone	An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
Methoxyflurane	For use in the induction and maintenance of general anesthesia
Mianserin	A tetracyclic antidepressant with therapeutic activity similar to amitriptyline used to treat depression and anxiety.
Pentoxifylline	A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Perphenazine	A phenothiazine used to treat schizophrenia as well as nausea and vomiting.
Selegiline	A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Theobromine	theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
Tolperisone	A muscle relaxant used to relieve spasticity after stroke in adults.
Ziprasidone	An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.
Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Cilostazol	An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
Eltrombopag	A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Clonidine	An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
Muraglitazar	Investigated for use/treatment in diabetes mellitus type 2.
Vadimezan	Investigated for use/treatment in solid tumors, lung cancer, ovarian cancer, and prostate cancer.
Nabumetone	An NSAID used to treat osteoarthritis and rheumatoid arthritis.
Pazopanib	An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
Ulipristal	A selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed.
Lorcaserin	A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities.
Apixaban	An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
Axitinib	An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
Pomalidomide	A thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
Ixazomib	A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
Bendamustine	An antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
Rucaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Icotinib	Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
Deutetrabenazine	A vesicular monoamine transporter 2 inhibitor used for the symptomatic treatment of tardive dyskinesia and chorea associated with Huntington's disease.
Stiripentol	An antiepileptic agent used in combination with other anticonvulsants to treat seizures associated with Dravet syndrome.
Voxilaprevir	A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
Enasidenib	An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Estradiol acetate	An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
Estradiol benzoate	An estrogen indicated in combination with progesterone for the treatment of irregular menstruation.
Estradiol cypionate	An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
Estradiol dienanthate	An estrogen used in some combined hormonal oral contraceptives.
Estradiol valerate	An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
Zotepine	Zotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes...
Lofexidine	A centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
Tasimelteon	A melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder.
Pirfenidone	An agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
Ramosetron	A selective 5-HT3 antagonist used as an antiemetic for chemotherapy- and postoperative-associated nausea and vomiting. It may also possess efficacy in irritable bowel syndrome.
Acetaminophen	An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
Clopidogrel	An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
Fluvoxamine	A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
Tegafur	An antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
Amiodarone	A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
Dihydralazine	Dihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
Pimobendan	Not Annotated
Ranitidine	A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
Perampanel	A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
(R)-warfarin	Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
6-O-benzylguanine	6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
8-chlorotheophylline	When used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
Hypoxanthine	Hypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
Lisofylline	Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Oxtriphylline	A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
Xanthine	A drug used to manage uncomplicated liver dysfunction in combination with orotic acid.
Temafloxacin	For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
Acefylline	Not Annotated
Acyclovir	A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
Bamifylline	A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm.
Bromotheophylline	Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
Bufylline	Not Annotated
Cafedrine	Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Doxofylline	A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms.
Entecavir	A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
Etamiphylline	Not Annotated
Fenethylline	Not Available
Lobucavir	Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Peldesine	Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Pemetrexed	A folate analog used to treat mesothelioma and non-small cell lung cancer.
Penciclovir	A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
Pentifylline	Not Annotated
Propentofylline	Investigated for use/treatment in alzheimer's disease.
Proxyphylline	Not Annotated
Theodrenaline	Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Propacetamol	Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
Nicotine	A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
Carmustine	An alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
Lomefloxacin	A fluoroquinolone used to prevent and treat a wide variety of infections in the body.
Hesperetin	For lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
Leflunomide	A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
Rofecoxib	A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
Thiabendazole	A benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
Nifedipine	A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
Primaquine	An antimalarial indicated to prevent relapse of vivax malaria.
Etoricoxib	A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
Praziquantel	An anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis.
Triamterene	A potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
Dasatinib	A tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia.
Benzyl alcohol	An antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
Capsaicin	A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Binimetinib	A medication used to treat metastatic melanoma with specific mutations.
Azathioprine	An immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
8-azaguanine	8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
9-Deazaguanine	Not Available
9-Methylguanine	Not Available
Disopyramide	A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
Alosetron	A 5-HT3 antagonist used to treat diarrhea-predominant IBS.
Sorafenib	A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.
Agomelatine	Agomelatine is indicated to treat major depressive episodes in adults.
Tocainide	An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
Triclabendazole	An anthelmintic drug used to treat fascioliasis.
Dapagliflozin	A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
Apremilast	A non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis.
Paroxetine	A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
Tamoxifen	A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
Istradefylline	A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease.
Efavirenz	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
Metoclopramide	An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
Loratadine	A second generation antihistamine used to manage the symptoms of allergic rhinitis.
GTS-21	Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders.
Bicifadine	For the treatment of pain.
Vortioxetine	A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD).
Formoterol	An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
Letrozole	An aromatase inhibitor used to treat breast cancer in postmenopausal women.
Halothane	A general inhalation anesthetic used for the induction and maintenance of general anesthesia.
Ifosfamide	An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Valproic acid	An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
Nevirapine	A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
Montelukast	A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
Cisapride	A medication used to treat heartburn associated with GERD.
Clomethiazole	Investigated for use/treatment in strokes.
Cyclophosphamide	A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
Flunitrazepam	A benzodiazepine used to manage anxiety disorders and insomnia.
Sevoflurane	A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
Zidovudine	A dideoxynucleoside used in the treatment of HIV infection.
Flurazepam	A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia.
Tretinoin	A vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
Arformoterol	A beta-2 adrenergic agonist and bronchodilator used for long-term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Tegafur-uracil	Tegafur-uracil is indicated for the first line treatment of metastatic colorectal cancer with concomitant administration of calcium folinate. Colorectal cancer is the third most diagnosed cancer and 30% of the...
Asunaprevir	An NS3 protease inhibitor used to treat hepatitis C genotype 1b.
Artesunate	Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
Metronidazole	A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
Plitidepsin	Intended for the treatment of various forms of cancer.
Bupropion	A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Meperidine	An opioid agonist with analgesic and sedative properties used to manage severe pain.
Propofol	A medication used in general anesthesia and for sedation.
Ketamine	A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
Dosulepin	A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential.
Trimipramine	A tricyclic antidepressant used to treat depression.
Ritonavir	An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Loperamide	A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
Perhexiline	For the management of severe angina pectoris.
Tramadol	A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
Sertraline	A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
Methylphenobarbital	For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
Irinotecan	An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Promethazine	A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
Seratrodast	Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Dextromethorphan	An NMDA receptor antagonist used to treat cases of dry cough.
Benzphetamine	A sympathomimetic used to manage exogenous obesity short term.
Artemether	An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
Brompheniramine	A histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
Clobazam	A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.
Clotiazepam	A thienodiazepine used to manage anxiety disorders and insomnia.
Epinastine	An H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
Ethylmorphine	An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine.
Isoflurane	An inhaled general anesthetic used in surgery.
Ketobemidone	For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
Methyltestosterone	A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
Permethrin	An insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
Temazepam	A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia.
Testosterone	A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
Banoxantrone	For the treatment of various forms of cancer.
Prasugrel	A P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI.
Ospemifene	A non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.
Romidepsin	A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.
Velpatasvir	A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
Brivaracetam	An anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain.
Testosterone cypionate	An androgen used to treat low or absent testosterone.
Testosterone enanthate	An androgen used to treat low or absent testosterone.
Testosterone undecanoate	An androgen indicated for testosterone replacement therapy in adult males with primary hypogonadism and hypogonadotropic hypogonadism.
Artemisinin	A medication indicated in the treatment of malaria.
Esketamine	A NMDA receptor antagonist used for treatment-resistant depression.
Hydrocodone	An opioid agonist used as an analgesic and antitussive agent.
Amlodipine	A calcium channel blocker used to treat hypertension and angina.
Diazepam	A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
Dexloxiglumide	For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD).
Metoprolol	A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
Venlafaxine	A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder.
Atomoxetine	A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
Codeine	An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
Timolol	A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
Oxycodone	An opioid used in the management of moderate to severe pain.
Thioridazine	A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.
Risperidone	A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
Flecainide	A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
Aripiprazole	An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
Tafenoquine	An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
Progesterone	A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
Elagolix	A gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.
Acebutolol	A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
Alprenolol	For the treatment of hypertension, angina, and arrhythmia
Anisodamine	Anisodamine has been investigated for the treatment of Intestinal Diseases.
Arotinolol	Artinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is...
Atenolol	A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
Befunolol	Used in the management of open angle glaucoma. PMID: 12480285.
Bevantolol	For the treatment of angina pectoris and hypertension.
Bopindolol	For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Bucindolol	Bucindolol has been investigated in Heart Failure.
Bufuralol	Bufuralol is a new, non-selective -adrenoceptor blocking agent.
Bupranolol	Used to manage hypertension and tachycardia. Also used to treat glaucoma.
Carteolol	A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
Celiprolol	A beta-blocker for the management of hypertension and angina pectoris.
Cloranolol	Not Annotated
Epanolol	Epanolol is an beta blocker.
Esatenolol	Esatenolol is a beta blocker.
Esmolol	A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
Indenolol	Indenolol is a drug of the beta-adrenergic blocker class.
Landiolol	An ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia.
Levobetaxolol	Used in the treatment of open-angle glaucoma and ocular hypertension [FDA Label].
Levobunolol	A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Mepindolol	Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.
Metipranolol	A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Nadolol	A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension.
Nebivolol	A beta blocking agent used to treat hypertension and aid in the management of heart failure.
Oxprenolol	A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
Penbutolol	A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents.
Pindolol	A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Practolol	Used in the emergency treatment of cardiac arrhythmias.
Sotalol	A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.
Talinolol	Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
Tertatolol	Tertatolol is a beta blocker.
Paliperidone	An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
Dapoxetine	A selective serotonin reuptake inhibitor used in the treatment of premature ejaculation.
Citalopram	A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
Escitalopram	A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
Levomilnacipran	A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults.
Nefazodone	An antidepressant used in the treatment of depression.
Trazodone	A serotonin uptake inhibitor used to treat major depressive disorder.
Fusidic acid	A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
Galantamine	A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
Dasabuvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Buprenorphine	A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Buspirone	An anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
Bepridil	For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
Fluvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Aripiprazole lauroxil	An antipsychotic used to treat schizophrenia in adults.
Zuclopenthixol	An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance.
Fesoterodine	An antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
Pitolisant	An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.
Brexpiprazole	A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease.
Eliglustat	A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers.
Amphetamine	A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
Cevimeline	A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome.
Prochlorperazine	A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.
Darifenacin	An M3 muscarinic receptor blocker used to treat urinary incontinence.
Nicergoline	An ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities.
Dolasetron	An antinauseant and antiemetic used in chemotherapy and postoperatively.
Minaprine	For the treatment of depression
Donepezil	An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
Phenformin	For the reatment of type II diabetes mellitus.
Almotriptan	A 5-HT1B/1D receptor agonist used to treat migraines.
Procainamide	A medication used to treat life threatening ventricular arrhythmias.
Tolterodine	A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
Chlorpheniramine	A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
Encainide	A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
Moclobemide	A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
Tiotropium	A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
Diphenhydramine	A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
Debrisoquine	For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
Gefitinib	A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
Terfenadine	An antihistamine for the treatment of allergy symptoms.
Diltiazem	A calcium channel blocker used to treat hypertension and to manage chronic stable angina.
Delavirdine	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
Mesoridazine	A phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses.
Mequitazine	For the treatment of Hay fever, urticaria (hives) and allergic rhinitis
Oxymorphone	An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
Methotrimeprazine	A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
Dihydrocodeine	An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Sertindole	An atypical antipsychotic indicated in the treatment of schizophrenia.
Tesmilifene	Intended for the treatment of various forms of cancer.
Rotigotine	A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome.
Lisuride	For the management of Parkinson's Disease
Trabectedin	An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
4-Methoxyamphetamine	Not Available
Sparteine	Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category...
Ticlopidine	A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
Amoxapine	A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
Chloroquine	An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
Iloperidone	An atypical antipsychotic agent used for the acute treatment of schizophrenia in adults.
Metamfetamine	A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.
Pipotiazine	An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients.
Tamsulosin	An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
Tetrabenazine	A vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease.
Tipranavir	A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
Dronedarone	An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
Eletriptan	A triptan used for the treatment of migraines.
Sildenafil	A phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
Amprenavir	A protease inhibitor used to treat HIV infection.
Aprindine	Aprindine is a cardiac depressant used in arrhythmias.
Astemizole	A second generation antihistamine used to treat allergy symptoms.
Benzatropine	An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
Bupivacaine	A local anesthetic used in a wide variety of superficial and invasive procedures.
Doxazosin	An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
Idarubicin	An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
Nateglinide	A meglitinide used to treat non insulin dependent diabetes mellitus.
Pentamidine	An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
Piperazine	A medication used to treat roundworm and pinworm.
Quetiapine	A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.
Remoxipride	An discontinued atypical antipsychotic selective for dopamine D2 receptors.
Simvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
Tegaserod	A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
Yohimbine	An alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Vilazodone	An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors.
Repinotan	Investigated for use/treatment in strokes, cerebral ischemia, and depression.
Clevidipine	A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
Enclomiphene	Not Annotated
Tapentadol	An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate.
Mirabegron	A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.
Ponatinib	A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
Alogliptin	A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Netupitant	An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy.
Umeclidinium	A long-acting muscarinic antagonist used as a long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD).
Cariprazine	An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
Esmirtazapine	Investigated for use/treatment in insomnia and sleep disorders.
Dexchlorpheniramine maleate	A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
Vernakalant	An antiarrhythmic medication used to treat patients with atrial fibrillation.
Valbenazine	A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia and chorea associated with Huntington's disease.
Perospirone	For the treatment of schizophrenia and acute cases of bipolar mania.
Rupatadine	A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
Letermovir	An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.
Opium	A medication used to treat moderate to severe pain.
Ibrutinib	An antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
Ipecac	An emetic agent used to induce vomiting in poisoning.
Lysergic acid diethylamide	Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
Encorafenib	A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
Lorpiprazole	In 2016, lorpiprazole was classified in the "Chemical structure-related drug-like criteria of global approved drugs" as an antipsychotic and anxiolytic. An antipsychotic is a medication used to treat a state...
Dextropropoxyphene	An opioid analgesic used to treat mild to moderate pain.
Midomafetamine	Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used...
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Revefenacin	An anticholinergic agent used to treat COPD.
Ranolazine	An anti-anginal drug used for the treatment of chronic angina.
Dextroamphetamine	A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Meclizine	A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
Dexchlorpheniramine	A chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin.
Solifenacin	A muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
Quinidine	A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Celecoxib	An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
Butyrfentanyl	A methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug.
Midodrine	An alpha-adrenergic agonist used to treat orthostatic hypotension.
Labetalol	An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
Oxamniquine	For treatment of Schistosomiasis caused by Schistosoma mansoni
Ciclesonide	A glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
Cannabidiol	An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Azimilide	Investigated for use/treatment in arrhythmia and atrial fibrillation.
5-methoxy-N,N-dimethyltryptamine	5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,...
Nabiximols	In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
Enflurane	A halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery.
Aniline	Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor...
Ethosuximide	An anticonvulsant used to treat petit mal seizures.
Nilvadipine	A calcium channel blocker used to manage arterial hypertension.
Trimethadione	An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.
Dichlorobenzene	Dichlorobenzene refers to any of, or a mixture of, three isomers consisting of benzene in which two of the hydrogen atoms are replaced by chlorine atoms: ortho-, meta-, and paradichlorobenzene....
Felbamate	An anticonvulsant used to treat severe epilepsy.
Nicotinamide	An ingredient found in a variety of cosmetic products.
Zafirlukast	A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
Losartan	An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
Irbesartan	An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
Ibuprofen	An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
Glipizide	A sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
Torasemide	A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
Phenytoin	An anticonvulsant drug used in the prophylaxis and control of various types of seizures.
Rosiglitazone	A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
Glyburide	A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
Piroxicam	An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
Phenprocoumon	An anticoagulant drug used for the prevention of thrombosis.
(S)-Warfarin	Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
Fluindione	Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for...
Lynestrenol	A progestin used for contraception and in the treatment of menstrual disorders.
Etravirine	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
Voriconazole	A triazole compound used to treat fungal infections.
Dicoumarol	For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
Phenylbutazone	An NSAID used to treat backache and ankylosing spondylitis.
Chlorpropamide	A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
Tolazamide	A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
Gliclazide	A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Glimepiride	A sulfonylurea drug used to treat type 2 diabetes mellitus.
Acetohexamide	Used in the management of diabetes mellitus type 2 (adult-onset).
Gliquidone	A sulfonylurea drug used in the management of diabetes mellitus type 2.
Glisoxepide	For the treatment of diabetes mellitus type 2.
Glibornuride	Glibornuride is a sulfonylurea-type anti-diabetic drug.
Carbutamide	Not Annotated
Metahexamide	Not Annotated
Fosphenytoin	An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
Enzalutamide	A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
Lansoprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Omeprazole	A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
Alprazolam	A triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
Rosuvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Bexarotene	A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
Bosentan	A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
Lacosamide	An antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures.
Primidone	An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
Dapsone	A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
Hydromorphone	An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
Tenoxicam	An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
Dronabinol	A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
Valdecoxib	A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
Paramethadione	Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications.
Flurbiprofen	An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Etodolac	An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Mefenamic acid	An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
Meloxicam	An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
Suprofen	An NSAID used to prevent pupil constriction in ocular surgery.
Sulfamethoxazole	An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
Candesartan cilexetil	An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
Atazanavir	An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Arachidonic Acid	A natural fatty acid that plays an essential role in physiological homeostases, such as repair and growth of cells.
Phenobarbital	A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
Mestranol	A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
Hexobarbital	For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
Valsartan	An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
Thalidomide	A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
Vicriviroc	Investigated for use/treatment in HIV infection and viral infection.
Lornoxicam	An NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis.
Trimethoprim	An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
Zopiclone	A nonbenzodiazepine hypnotic used for the short-term management of insomnia.
Sitaxentan	Investigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.
Indomethacin	A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Salicylic acid	An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Ketoprofen	An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
Licofelone	For the management of osteoarthritis.
Zaltoprofen	A non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
Aceclofenac	Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Acetylsalicylic acid	A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
Dorzolamide	A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
Pioglitazone	A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus.
Proguanil	A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
Quazepam	A long-acting benzodiazepine used to manage insomnia.
Troglitazone	For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
Indisulam	Investigated for use/treatment in lung cancer.
Niclosamide	An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
Thiamylal	Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
Vismodegib	A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
Treprostinil	A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
Pitavastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Cabozantinib	A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
Olodaterol	A long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Parecoxib	A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
Lesinurad	A uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
Doconexent	An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
Candesartan	An angiotensin-receptor blocker indicated in the treatment of hypertension.
Piperaquine	For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
Bioallethrin	Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
Medical Cannabis	The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
Ximelagatran	For the treatment of acute deep vein thrombosis.
Tolbutamide	A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Coumarin	Not Available
Tranilast	For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
Desogestrel	A synthetic progestin used in contraception, often in combination with ethinyl estradiol.
Siponimod	A medication used to treat relapsing multiple sclerosis.
Erdafitinib	A fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma.
Dexibuprofen	A pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation.
Ketorolac	An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
Capravirine	Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Pantoprazole	A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
Carisoprodol	A centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions.
Esomeprazole	A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
Dexrabeprazole	A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
Rabeprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Barbital	A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
Pentobarbital	A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
Thiopental	A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
Methsuximide	A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
Lapatinib	An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments.
Zonisamide	A sulfonamide anticonvulsant used to treat partial seizures.
St. John's Wort	An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
Lorlatinib	An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Etizolam	A thienodiazepine derivative used to treat anxiety and insomnia.
Dexlansoprazole	A proton pump inhibitor used to treat erosive esophagitis, heartburn, and gastroesophageal reflux disease (GERD).
Fedratinib	Fedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis.[L8090,L47016]
Cerivastatin	A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events.
Repaglinide	A antihyperglycemic used to improve glycemic control in diabetes.
Paclitaxel	A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
Amodiaquine	An antimalarial drug.
Balaglitazone	Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Ciglitazone	Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in...
Lobeglitazone	Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use...
Netoglitazone	Netoglitazone (MCC-555) is a hypoglycemic agent.
Rivoglitazone	Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co.
Ombitasvir	A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Atorvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Diethylstilbestrol	Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
Ethinylestradiol	An estradiol used as a contraceptive.
Sitagliptin	An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
Eszopiclone	A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
Cabazitaxel	An antineoplastic agent used in combination with corticosteroids to treat metastatic castration-resistant prostate cancer in patients previously treated with a docetaxel-containing treatment regimen.
Halofantrine	An antimalarial used for the treatment of severe malaria.
Morphine	An opioid agonist used for the relief of moderate to severe acute and chronic pain.
Sulfadiazine	A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
Tazarotene	An acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
Beraprost	For the treatment of pulmonary hypertension.
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Mycophenolate mofetil	An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.
Selexipag	A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
Riociguat	A stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.
Odanacatib	Investigated for use/treatment in osteoporosis .
Brigatinib	An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Apalutamide	An androgen receptor inhibitor used to treat non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer.
Nicardipine	A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
Glasdegib	A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
Lovastatin	An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
Indinavir	A protease inhibitor used to treat HIV infection.
Nisoldipine	A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
Vincristine	A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Midazolam	A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders.
Alfentanil	An opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
Tadalafil	A phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
Vardenafil	A phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
Tacrolimus	A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
Sirolimus	An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.
Triazolam	A benzodiazepine used for short term treatment of insomnia.
Telithromycin	An ketolide used to treat community acquired pneumonia of mild to moderate severity.
Felodipine	A calcium channel blocker used to treat hypertension.
Nitrendipine	A dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension.
Clarithromycin	A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
Saquinavir	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
Erythromycin	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.
Cyclosporine	A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Azithromycin	A macrolide antibiotic used to treat a variety of bacterial infections.
Telaprevir	An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.
Boceprevir	A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
Isavuconazole	Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Fosamprenavir	An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
Simeprevir	A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
Temsirolimus	A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
Avanafil	A phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction.
Conivaptan	An antidiuretic hormone inhibitor used to raise serum sodium levels.
Darunavir	A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
Ebastine	A second generation H1-receptor antagonist useful in the treatment of allergic rhinitis and urticaria.
Everolimus	A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
Lomitapide	A microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke.
Naloxegol	A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
Budesonide	A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
Eplerenone	An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
Lurasidone	An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
Maraviroc	A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
Ticagrelor	A P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
Tolvaptan	A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia.
Aprepitant	A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
Colchicine	An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events.
Rilpivirine	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
Rivaroxaban	A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
Methysergide	An ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
Tianeptine	An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder.
Bromocriptine	A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
Cabergoline	A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
Dihydroergocornine	A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Dihydroergocristine	An ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
Dihydroergocryptine	A dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis.
Dihydroergotamine	An ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
Ergoloid mesylate	A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Ergometrine	An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony.
Ergotamine	An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
Methylergometrine	An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery.
Terguride	Not Annotated
Triamcinolone	A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Lopinavir	An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
Teniposide	A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
Alfuzosin	An alpha-1 adrenergic antagonist used in the symptomatic management of benign prostatic hypertrophy (BPH).
Fostamatinib	A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
Udenafil	A PDE5 inhibitor used to treat erectile dysfunction.
Prednisone	A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Fluticasone	A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD.
Lacidipine	A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension.
Allylestrenol	A steroid used to prevent premature labour in pregnant women.
Betamethasone	A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Cortisone acetate	A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Deflazacort	A corticosteroid used to treat Duchenne muscular dystrophy.
Dienogest	An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
Dexamethasone	A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Dexamethasone isonicotinate	Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Drospirenone	A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
Etonogestrel	A long-acting synthetic derived progestin contraceptive used in various devices such as contraceptive rings and intradermal implants.
Flunisolide	An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Fluocortolone	A glucocorticoid used topically for localized skin reactions and also orally for systemic use.
Fluorometholone	An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
Fluticasone furoate	An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
Fluticasone propionate	A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
Hydrocortisone	A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Hydrocortisone aceponate	For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone acetate	A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
Hydrocortisone butyrate	A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone cypionate	For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone phosphate	A corticosteroid used to treat congenital adrenal hyperplasia, for emergency asthma treatment, hypersensitivity, and inflammation.
Hydrocortisone probutate	A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone valerate	A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydroxyprogesterone caproate	A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
Levonorgestrel	A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.
Medroxyprogesterone acetate	A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
Methylprednisolone	A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Norethisterone	A synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis.
Norgestimate	A progesterone used as a contraceptive and to treat acne vulgaris.
Norgestrel	A progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
Paramethasone	For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
Prasterone	A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
Prednisolone	A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Diphenadione	Not Annotated
Ethyl biscoumacetate	Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Azelnidipine	For the treatment of hypertension.
Barnidipine	A calcium channel blocker used to treat various forms of hypertension.
Bencyclane	A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
Benidipine	A synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris.
Carboxyamidotriazole	Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Caroverine	A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus.
Cilnidipine	A dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension.
Cyclandelate	A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
Darodipine	Darodipine is a calcium channel blocker.
Dexniguldipine	Not Annotated
Dexverapamil	Not Annotated
Dotarizine	A calcium antagonist used to treat and prevent migraines.
Efonidipine	For the treatment of hypertension.
Emopamil	Prevents renal injury after warm & cold ischemia.
Eperisone	An antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles.
Fendiline	Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Fish oil	A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement.
Fluspirilene	An antipsychotic agent used in the treatment of schizophrenia.
Gallopamil	Gallopamil has been used in trials studying the treatment of Asthma.
Isradipine	A dihydropyridine calcium channel blocker used for the treatment of hypertension.
Lercanidipine	A calcium channel blocker for the management of hypertension.
Lidoflazine	Not Annotated
Lomerizine	Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated...
Manidipine	A dihydropyridine calcium channel blocker used to treat hypertension.
Levomenthol	An organic compound used to treat mild to moderate muscle and joint pain.
Mibefradil	For the treatment of angina and high blood pressure.
Naftopidil	Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Niludipine	Niludipine is a calcium channel blocker.
Nimesulide	A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
Nimodipine	A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
Nylidrin	A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
Niguldipine	Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
Otilonium	A spasmolytic medication used to treat irritable bowel syndrome (IBS).
Penfluridol	Not Annotated
Pinaverium	A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
Prenylamine	Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Terodiline	Not Annotated
Tetrahydropalmatine	Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Tetrandrine	Not Annotated
Tolfenamic acid	In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
Trimebutine	A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
Seletracetam	Investigated for use/treatment in epilepsy.
Vinpocetine	A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
WIN 55212-2	WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
Ivermectin	An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
Ixabepilone	A microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.
Rifabutin	An antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
Rifapentine	An antibiotic agent used in the treatment of pulmonary tuberculosis.
Rifaximin	A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
Regorafenib	A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
Ivabradine	A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.
Vemurafenib	A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
Crizotinib	A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
Isavuconazonium	A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis.
Dofetilide	A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
Reboxetine	A drug used for the acute treatment of major depression and for maintenance therapy of depression.
Vindesine	A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
Vinorelbine	A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
Toremifene	A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
Vinblastine	A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Clofibrate	A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol.
Modafinil	A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
Roxithromycin	An antibiotic used to treat a variety of susceptible bacterial infections.
Fentanyl	An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
Mifepristone	A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
Granisetron	A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.
Tiagabine	An antiepileptic used to treat partial seizures.
Cocaine	An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
Paricalcitol	A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.
Tinidazole	A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
Salmeterol	A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
Zaleplon	A sedative used for short term treatment of insomnia in adults.
Exemestane	An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
Doxorubicin	A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
Busulfan	An alkylating agent used to treat chronic myelogenous leukemia.
Ketoconazole	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Oxybutynin	An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
Clonazepam	A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
Sibutramine	A norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
Dutasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
Itraconazole	An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
Clindamycin	A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Estazolam	A benzodiazepine used for the short-term management of insomnia.
Finasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
Levacetylmethadol	For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
Retapamulin	A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.
Sunitinib	A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Posaconazole	A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Rimonabant	For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated...
Laquinimod	Investigated for use/treatment in multiple sclerosis.
Docetaxel	A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Ambrisentan	A selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
Bisoprolol	A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
Calcitriol	An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
Chlordiazepoxide	A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
Clorazepic acid	A benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal.
Digitoxin	A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Guanfacine	An alpha-2A adrenergic receptor agonist used to treat ADHD.
Mefloquine	An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.
Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Silodosin	An alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.
Saxagliptin	An DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
Sufentanil	An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
Bicalutamide	An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
Sulfinpyrazone	A platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
Adinazolam	For the treatment of anxiety and status epilepticus.
Vanoxerine	An investigational dopamine transporter antagonist suggested to be beneficial in the treatment of cocaine addiction.
Cholecalciferol	A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
Orphenadrine	A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
Desvenlafaxine	An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
Lumefantrine	An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
Ambroxol	A medication indicated for airway secretion clearance therapy.
Argatroban	A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
Bezafibrate	A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder.
Brinzolamide	A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Cephalexin	A first generation cephalosporin used to treat certain susceptible bacterial infections.
Cytarabine	A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Daunorubicin	An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Disulfiram	A carbamate derivative used to treat alcohol addiction.
Estramustine	An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
Fenofibrate	A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
Fulvestrant	An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
Imiquimod	A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
Quinacrine	For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
Methaqualone	For the treatment of insomnia, and as a sedative and muscle relaxant.
Nitrazepam	A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
Olopatadine	A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
Prazepam	A benzodiazepine used to manage more severe forms of anxiety disorders.
Tasosartan	Tasosartan is infrequently in the treatment of hypertension and heart failure.
Thiotepa	An alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
Troleandomycin	For the treatment of bacterial infection.
Zomepirac	Zomepirac was indicated for the management of mild to severe pain.
Ketazolam	A long-acting benzodiazepine used to manage anxiety and insomnia.
Indapamide	A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
Ivacaftor	A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication.
Indacaterol	An inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
Chenodeoxycholic acid	A bile acid used for the treatment of primary biliary cirrhosis.
Pinacidil	Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
Pimecrolimus	A topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
Brentuximab vedotin	A CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
Vandetanib	An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
Ruxolitinib	A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
Abiraterone	An antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer.
Tofacitinib	A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis.
Bosutinib	An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
Bedaquiline	A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).
Canagliflozin	A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
Trastuzumab emtansine	An antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
Taurochenodeoxycholic acid	Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy.
Macitentan	An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Palbociclib	An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Vilanterol	A long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Aliskiren	A direct renin inhibitor used to manage hypertension.
Elvitegravir	An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
Rolapitant	A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.
Flibanserin	A 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD).
Daclatasvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Sonidegib	An antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate.
Panobinostat	A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
Paritaprevir	A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Synthetic Conjugated Estrogens, A	A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal atrophy and dyspareunia.
Synthetic Conjugated Estrogens, B	A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal dryness.
Venetoclax	A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Esterified estrogens	A female hormone used to treat conditions related to estrogen deficiency and moderate to severe vasomotor menopausal symptoms in women.
Safinamide	A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
Grazoprevir	An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
Imidafenacin	An antispasmodic with anticholinergic effects used to reduce urinary frequency.
Neratinib	A protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.
Midostaurin	An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
Elbasvir	An antiviral and NS5A inhibitor used to treat hepatitis C infections.
Copanlisib	A PI3K inhibitor used to treat relapsed follicular lymphoma in adults.
Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.
Baricitinib	A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
Macimorelin	A medication used to treat adult growth hormone deficiency.
Blonanserin	Used for the treatment of schizophrenia .
Testosterone propionate	A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles.
Bictegravir	An integrase inhibitor used to treat HIV infections.
Tezacaftor	A medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis.
Tocopherol	Tocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
alpha-Tocopherol acetate	A form of vitamin E used to treat and prevent vitamin deficiencies.
Propiverine	An antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
Vinflunine	A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
Tocofersolan	A derivative of alpha tocopherol used to treat vitamin E deficiencies.
Delamanid	An antibiotic used to treat multidrug resistant tuberculosis.
Fosnetupitant	A medication used in combination with others to prevent chemotherapy associated nausea and vomiting.
Dihydro-alpha-ergocryptine	A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Midecamycin	A macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.
Segesterone acetate	Segesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen...
Cobicistat	A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
Methotrexate	An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Linagliptin	A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
Cobimetinib	An antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma.
Osimertinib	A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
Ceritinib	An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
Ribociclib	A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
Nintedanib	A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
Roflumilast	A selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat plaque psoriasis.
Suvorexant	A orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance.
Vorapaxar	A platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD).
Idelalisib	An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
Pranlukast	A leukotriene receptor antagonist for the treatment of allergic rhinitis and asthma symptoms.
Eravacycline	A tetracycline antibiotic used to treat complicated intra-abdominal infections.
Fosaprepitant	An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy.
Cethromycin	A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia.
Doravirine	A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.
Duvelisib	An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Ivosidenib	An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.
3,5-diiodothyropropionic acid	DITPA has been investigated in Congestive Heart Failure.
5-androstenedione	5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its...
Alclometasone	A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
Aldosterone	A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Amcinonide	A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
Androstenedione	A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as...
Beclomethasone dipropionate	An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
Clobetasol	Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Clobetasol propionate	A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
Clobetasone	A corticosteroid used to treat dry eyes, eczema, and dermatitis.
Corticosterone	An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Corticotropin	A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cyproterone acetate	A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
Nomegestrol	Nomegestrol is an ingredient in the EMA-authorised product Zoely.
Nomegestrol acetate	Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Desonide	A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Desoxycorticosterone acetate	Not Annotated
Desoxycorticosterone pivalate	Examined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of...
Difluocortolone	A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
Difluprednate	A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
Dydrogesterone	A synthetic progesterone for menstrual cycle regulation, infertility treatment, prevention of miscarriage, and other conditions.
Equilenin	Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine...
Equilin	For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and...
Etynodiol	Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers...
Ethynodiol diacetate	An oral contraceptive used to prevent pregnancy.
Fludrocortisone	A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
Flumethasone	A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
Fluocinolone acetonide	A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
Fluocinonide	A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
Fluprednidene	Fluprednidene is a corticosteroid.
Fluprednisolone	A synthetic glucocorticoid with anti-inflammatory properties.
Flurandrenolide	A corticosteroid used to treat corticosteroid-responsive dermatoses.
Gestodene	Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
Halcinonide	A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
HE3286	For the treatment of rheumatoid arthritis and type 2 diabetes.
Hydrocortisone succinate	A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Hydroxyprogesterone	Not Annotated
Liotrix	May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic...
Loteprednol etabonate	A corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery.
Medrogestone	A progestin used as an adjunct to control secondary amenorrhea and dysfunctional bleeding in adolescent and adult females, and treat endometrial shedding in menopausal women.
Medrysone	A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
Megestrol acetate	A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
Melengestrol	Melengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
Meprednisone	Not Annotated
Mometasone	A corticosteroid with no indications.
Mometasone furoate	A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
Norelgestromin	A progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception.
Norethynodrel	A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it...
Prednicarbate	A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
Prednylidene	Prednylidene is an experimental systemic glucocorticoid.
Pregnenolone	A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Promegestone	Not Annotated
Rimexolone	A glucocorticoid used to treat inflammation of the eye.
Atovaquone	An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
Gestrinone	Endometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].
Chlormadinone	A progestin indicated in combination with an estrogen for oral combined hormonal contraceptive therapy.
Quingestanol	Not Annotated
Demegestone	Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Agmatine	Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,...
Gemfibrozil	A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Indalpine	Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse...
Milnacipran	A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
Aranidipine	Aranidipine has been used for many years to treat angina pectoris and hypertension.
Lenvatinib	A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
Lorazepam	A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
9-aminocamptothecin	Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Methylprednisone	Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Larotrectinib	A kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments.
Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
1,2-Benzodiazepine	Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary...
Brotizolam	A benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia.
Vitamin D	An ingredient found in a variety of supplements and vitamins.
SN-38	Investigated for use/treatment in colorectal cancer.
Prucalopride	A 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation.
Phentermine	A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
Tenofovir alafenamide	A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
Alpelisib	Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer. This cancer must be hormone receptor (HR)-positive, human epidermal growth factor...
Selinexor	Selinexor is indicated in combination with bortezomib and dexamethasone for the treatment of multiple myeloma in adult patients who have received at least one prior therapy. Selinexor is also indicated...
Clotrimazole	A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Vitamin E	An antioxidant vitamin used in many skin creams and multivitamin preparations.
Isotretinoin	A retinoid used to treat severe recalcitrant acne.
Levocetirizine	An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.
Pexidartinib	An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Bimatoprost	A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
Pretomanid	Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.
Hydroxychloroquine	An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
Entrectinib	Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
Lefamulin	A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP).
Flucloxacillin	A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA).
Mexazolam	A benzodiazepine indicated to treat anxiety with or without psychoneurotic conditions.
Calanolide A	For use in combination treatment of HIV infection (AIDS).
Rifalazil	Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease.
Polatuzumab vedotin	A CD79b antibody conjugate indicated to treat different types of large B-cell lymphoma.
Levamlodipine	A calcium channel blocker used to treat hypertension.
Fluprednisolone acetate	Not Annotated
Baloxavir marboxil	A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
Tenapanor	An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic kidney disease,
Anastrozole	A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Trifarotene	A topical retinoid indicated for the treatment of acne vulgaris.
Elexacaftor	A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.
Mitoxantrone	A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
Fomepizole	An inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
Isoniazid	An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
Dexmedetomidine	An alpha-2 agonist used for sedation during various procedures.
Enfuvirtide	An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
Tirapazamine	For the treatment of head and neck cancer.
Dalfampridine	A potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
Fingolimod	A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19.
N-Methyl-N-(Methylbenzyl)Formamide	Not Available
1,2-dichlorobenzene	1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
N,N-dimethylformamide	Not Available
Nilutamide	An antineoplastic hormone used to treat prostate cancer.
Oxiconazole	A topical antifungal used to treat a variety of dermatophyte infections.
Prednisolone acetate	A glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions.
Hydroxyzine	An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
Zanubrutinib	A kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
Voxelotor	A drug used to inhibit the polymerization of hemoglobin S, preventing the painful and sometimes lethal vaso-occlusive crises associated with sickle cell disease.
Cenobamate	A small molecule drug indicated to treat partial onset seizures in adults.
Enfortumab vedotin	An antibody-drug conjugate comprised of a fully human monoclonal antibody and microtubule-disrupting chemotherapeutic agent used in the treatment of advanced or metastatic urothelial cancer.
Trastuzumab deruxtecan	An antibody used to treat certain types of unresectable or metastatic HER2 positive breast cancer.
Lemborexant	A dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia.
Darolutamide	An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer and metastatic hormone-sensitive prostate cancer.
Lumateperone	A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia.
Upadacitinib	An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, and severe atopic dermatitis, including in patients who did not respond well to other therapies.
Ubrogepant	An oral CGRP antagonist used in the acute treatment of migraine with or without aura.
Avapritinib	A selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors.
Tazemetostat	A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Rimegepant	An oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults.
Umifenovir	A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses.
Osilodrostat	An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Norethindrone enanthate	A synthetic progestogen indicated for contraceptive therapy.
Ozanimod	A sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD).
Selumetinib	A MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN).
Prednisolone phosphate	A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
Tucatinib	A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer.
Pemigatinib	A kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
Remdesivir	A nucleoside analog used to treat RNA virus infections including COVID-19.
Acalabrutinib	A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
Capmatinib	A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
Alectinib	A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Belinostat	A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
Capecitabine	A nucleoside metabolic inhibitor indicated to treat different gastrointestinal, including pancreatic cancer, and breast cancer.
Selpercatinib	A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.
Ripretinib	A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST).
Apomorphine	A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
Betamethasone phosphate	A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Lurbinectedin	A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer.
Dexamethasone acetate	Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Fenfluramine	Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
Fostemsavir	An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
Abametapir	A pediculicide metalloproteinase used topically in the treatment of head lice infection.
Risdiplam	An oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA).
Oliceridine	A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists.
Pralsetinib	A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Lonafarnib	A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies.
Tirbanibulin	A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
Relugolix	An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
Vibegron	A beta-3 adrenergic agonist the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.
Desflurane	A general inhalation anesthetic for inpatient and outpatient surgery in adults.
Oxymetazoline	An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea.
Methylene blue	An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Tepotinib	An oral tyrosine kinase inhibitor targeted against MET for the treatment of metastatic non-small cell lung cancer in patients exhibiting MET exon 14 skipping mutations.
Voclosporin	A calcineurin inhibitor for the treatment of lupus nephritis (LN) in patients diagnosed with systemic lupus erythematosus (SLE).
Scopolamine	A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).
Umbralisib	A kinase inhibitor used to treat rare forms of refractory lymphoma.
Febuxostat	A xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol.
Benzocaine	A topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
Tivozanib	A kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease.
Ponesimod	A sphingosine 1-phosphate receptor modulator indicated to treat relapsing multiple sclerosis.
Pimavanserin	A second generation atypical antipsychotic used for the treatment of hallucinations and delusions caused by Parkinson's Disease.
Azilsartan medoxomil	An angiotensin II receptor blocker used to treat hypertension alone or in combination with other antihypertensive agents, such as chlorthalidone.
Glycopyrronium	An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
Estetrol	An estrogen used in combination with drospirenone for oral contraception.
Loncastuximab tesirine	An antibody-drug conjugate used for the treatment of relapsed and refractory B-cell lymphomas.
Naloxone	An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
Sotorasib	An experimental KRAS inhibitor being investigated for the treatment of KRAS G12C mutant non small cell lung cancer, colorectal cancer, and appendix cancer.
Infigratinib	An FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement.
Samidorphan	A novel opioid-system modulator, similar to naltrexone, that functions primarily as a μ-opioid receptor antagonist in vivo and is used primarily in combination with antipsychotics to reduce their metabolic dysfunction-associated adverse effects.
Ibrexafungerp	A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.
Finerenone	A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes.
Belumosudil	An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
Belzutifan	An inhibitor of hypoxia-inducible factor 2α used as an antineoplastic in the treatment of certain cancers associated with von Hippel-Lindau (VHL) disease.
Fexinidazole	An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Tisotumab vedotin	A tissue factor-directed antibody drug conjugate that is used to treat adults with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy.
Mobocertinib	An oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations.
Vicagrel	Vicagrel is under investigation in clinical trial NCT03599284 (The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel).
Atogepant	An oral CGRP antagonist used for the preventative therapy of episodic migraine headaches.
Avacopan	An orally bioavailable complement 5a receptor (C5aR) antagonist for the treatment of severe anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis.
Asciminib	An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Maribavir	A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection.
Nirmatrelvir	An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
Levoketoconazole	One of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.
Daridorexant	A dual orexin receptor antagonist used to treat insomnia in adults.
Sotagliflozin	An orally administered dual SGLT1/2 inhibitor used alongside insulin to improve glycemic control in patients with type 1 diabetes mellitus.
Abrocitinib	A kinase inhibitor used to treat moderate-to-severe atopic dermatitis in adults.
Palovarotene	A selective agonist of retinoic acid receptor gamma (RARγ) used to reduce heterotopic ossification in patients with Fibrodysplasia Ossificans Progressiva (FOP).
Roxadustat	A hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease.
Mitapivat	A pyruvate kinase activator used to treat hemolytic anemia in adults with pyruvate kinase (PK) deficiency.
Secnidazole	A nitroimidazole antibiotic used to treat bacterial vaginosis.
Nabilone	A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
Cannabinol	Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Nalmefene	An opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose.
Pacritinib	A kinase inhibitor used for the treatment of primary and secondary myelofibrosis in adult patients with significantly reduced platelet counts.
Ganaxolone	A neuroactive steroid GABA-A receptor modulator used for the treatment of seizures associated with CDKL5 deficiency disorder (CDD).
Viloxazine	A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.
Mavacamten	A myosin inhibitor used to treat obstructive hypertrophic cardiomyopathy.
Tapinarof	A therapeutic aryl hydrocarbon receptor-modulating agent (TAMA) indicated for the treatment of adult psoriasis.
Mycophenolic acid	An immunosuppressant used to prevent organ transplant rejections.
Terpinen-4-ol	Terpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Lenacapavir	A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment.
Deucravacitinib	A TYK2 inhibitor being investigated as a treatment for psoriasis.
Futibatinib	A kinase inhibitor used to treat intrahepatic cholangiocarcinoma in previously treated adults.
Linzagolix	A selective gonadotropin-releasing hormone (GnRH) receptor antagonist used for the symptomatic treatment of uterine fibroids.
Vonoprazan	A potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication.
Mirvetuximab soravtansine	A folate receptor alpha-directed antibody and microtubule inhibitor conjugate used to treat folate receptor alpha positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.
Olutasidenib	An isocitrate dehydrogenase-1 (IDH1) inhibitor indicated for the treatment of patients with relapsed or refractory acute myeloid leukemia with a susceptible IDH1 mutation as detected by an FDA-approved test.
Adagrasib	A KRAS inhibitor indicated for the treatment of locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer in patients who have received at least one prior systemic therapy.
Bexagliflozin	A sodium-glucose co-transporter 2 inhibitor used to improve glycemic control in patients with type 2 diabetes mellitus.
Elacestrant	An estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
Pirtobrutinib	A kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
Daprodustat	A small-molecule hypoxia-inducible factor prolyl hydroxylase inhibitor used for the treatment of anemia in patients with chronic kidney disease.
Sparsentan	An endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression.
Omaveloxolone	A semisynthetic triterpenoid used to treat Friedreich’s ataxia in adults and adolescents 16 years and older.
Zavegepant	A calcitonin gene-related peptide receptor antagonist indicated for the acute treatment of migraine with or without aura.
Trametinib	A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer.
Leniolisib	A phosphoinositide 3-kinase-delta inhibitor that is used to treat activated phosphoinositide 3-kinase delta syndrome.
Fezolinetant	A non-hormonal drug used to treat moderate to severe vasomotor symptoms due to menopause
Momelotinib	A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis.
Quizartinib	A FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication
Ritlecitinib	A kinase inhibitor used to treat severe alopecia areata in adults and adolescents 12 years and older.
Zuranolone	A neuroactive steroid drug used to treat postpartum depression
Gepirone	A serotonin receptor agonist used to treat major depressive disorder in adults
Etrasimod	An S1P receptors modulator used to treat moderate to severely active ulcerative colitis in adults
Vamorolone	A synthetic glucocorticoid used as an anti-inflammatory and immunosuppressant in the management of Duchenne muscular dystrophy (DMD).
Capivasertib	A serine/threonine kinase inhibitor used to treat hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer
Repotrectinib	A tyrosine kinase inhibitor used to treat locally active or metastatic non-small cell lung cancer
Fruquintinib	A VEGF receptor inhibitor used to treat metastatic colorectal cancer.
Pilocarpine	A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.
Nirogacestat	A gamma-secretase inhibitor used to treat desmoid tumors
Iptacopan	A factor B inhibitor used to treat paroxysmal nocturnal hemoglobinuria.

Drugs & Drug Targets

Drug	Target	Type
Bortezomib	Cytochrome P450 3A4	enzyme
Bortezomib	Cytochrome P450 2C19	enzyme
Bortezomib	Cytochrome P450 1A2	enzyme
Bortezomib	Cytochrome P450 2D6	enzyme
Bortezomib	Cytochrome P450 2C9	enzyme
Bortezomib	Proteasome subunit beta type-5	target
Bortezomib	Proteasome subunit beta type-1	target
Bortezomib	P-glycoprotein 1	transporter
Bortezomib	Solute carrier organic anion transporter family member 1B3	transporter
Caffeine	Adenosine receptor A1	target
Caffeine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Caffeine	Adenosine receptor A2a	target
Caffeine	Cytochrome P450 1A2	enzyme
Caffeine	Ryanodine receptor 1	target
Caffeine	Cytochrome P450 3A4	enzyme
Caffeine	Cytochrome P450 2E1	enzyme
Caffeine	Cytochrome P450 2C8	enzyme
Caffeine	Cytochrome P450 2C9	enzyme
Caffeine	Cytochrome P450 1A1	enzyme
Caffeine	Cytochrome P450 1B1	enzyme
Caffeine	Cytochrome P450 2D6	enzyme
Caffeine	Cyclic nucleotide phosphodiesterase	target
Caffeine	DNA-dependent protein kinase catalytic subunit	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	target
Caffeine	Inositol 1,4,5-trisphosphate receptor	target
Caffeine	Serine-protein kinase ATM	target
Caffeine	ATP-binding cassette sub-family G member 2	transporter
Caffeine	Adenosine receptor A2b	target
Caffeine	Adenosine receptor A3	target
Caffeine	Phosphodiesterase enzymes	target
Anagrelide	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Anagrelide	Cytochrome P450 1A2	enzyme
Ropinirole	Dopamine D2 receptor	target
Ropinirole	Dopamine D3 receptor	target
Ropinirole	Dopamine D4 receptor	target
Ropinirole	Cytochrome P450 1A2	enzyme
Ropinirole	Alpha adrenergic receptor	target
Theophylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Theophylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Theophylline	Adenosine receptor A2b	target
Theophylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Theophylline	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Theophylline	Adenosine receptor A1	target
Theophylline	Adenosine receptor A2a	target
Theophylline	Cytochrome P450 1A2	enzyme
Theophylline	Adenosine deaminase	enzyme
Theophylline	Cytochrome P450 2E1	enzyme
Theophylline	Cytochrome P450 3A4	enzyme
Theophylline	Solute carrier family 22 member 7	transporter
Theophylline	Cytochrome P450 1A1	enzyme
Theophylline	Cytochrome P450 1B1	enzyme
Theophylline	Cytochrome P450 2D6	enzyme
Theophylline	Histone deacetylase 2	target
Theophylline	Copine-1	target
Theophylline	Minor histocompatibility antigen H13	target
Theophylline	Nodal modulator 1	target
Theophylline	Poly [ADP-ribose] polymerase 1	target
Theophylline	Protein RIC-3	target
Theophylline	Tubulin monoglycylase TTLL3	target
Lidocaine	Sodium channel protein type 5 subunit alpha	target
Lidocaine	Sodium channel protein type 10 subunit alpha	target
Lidocaine	Epidermal growth factor receptor	target
Lidocaine	Sodium channel protein type 9 subunit alpha	target
Lidocaine	Cytochrome P450 1A2	enzyme
Lidocaine	Cytochrome P450 2D6	enzyme
Lidocaine	Cytochrome P450 3A4	enzyme
Lidocaine	Cytochrome P450 3A5	enzyme
Lidocaine	Cytochrome P450 3A7	enzyme
Lidocaine	Solute carrier family 22 member 5	transporter
Lidocaine	P-glycoprotein 1	transporter
Lidocaine	Cytochrome P450 2A6	enzyme
Lidocaine	Cytochrome P450 2B6	enzyme
Lidocaine	Cytochrome P450 2C8	enzyme
Lidocaine	Cytochrome P450 2C9	enzyme
Lidocaine	Sodium channel protein type 4 subunit alpha	target
Lidocaine	Alpha-1-acid glycoprotein 1	target
Lidocaine	Alpha-1-acid glycoprotein 2	target
Conjugated estrogens	Estrogen receptor alpha	target
Conjugated estrogens	Cytochrome P450 3A4	enzyme
Conjugated estrogens	Cytochrome P450 1A2	enzyme
Conjugated estrogens	Catechol O-methyltransferase	enzyme
Conjugated estrogens	Canalicular multispecific organic anion transporter 2	transporter
Conjugated estrogens	Multidrug resistance-associated protein 4	transporter
Conjugated estrogens	Multidrug resistance-associated protein 1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1A2	transporter
Conjugated estrogens	Sodium/bile acid cotransporter	transporter
Conjugated estrogens	Solute carrier family 22 member 10	transporter
Conjugated estrogens	Solute carrier family 22 member 8	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1C1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1B1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 2B1	transporter
Conjugated estrogens	P-glycoprotein 1	transporter
Conjugated estrogens	Solute carrier family 22 member 6	transporter
Conjugated estrogens	Organic solute transporter subunit alpha	transporter
Conjugated estrogens	Organic solute transporter subunit beta	transporter
Conjugated estrogens	Canalicular multispecific organic anion transporter 1	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 4A1	transporter
Conjugated estrogens	ATP-binding cassette sub-family C member 11	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 1B3	transporter
Conjugated estrogens	Solute carrier family 22 member 11	transporter
Conjugated estrogens	Solute carrier organic anion transporter family member 3A1	transporter
Conjugated estrogens	ATP-binding cassette sub-family G member 2	transporter
Conjugated estrogens	Thyroxine-binding globulin	carrier
Conjugated estrogens	Sex hormone-binding globulin	carrier
Conjugated estrogens	Serum albumin	carrier
Conjugated estrogens	Estrogen receptor beta	target
Ropivacaine	Sodium channel protein type 10 subunit alpha	target
Ropivacaine	Cytochrome P450 1A2	enzyme
Ropivacaine	Cytochrome P450 2B6	enzyme
Ropivacaine	Cytochrome P450 3A4	enzyme
Ropivacaine	Alpha-1-acid glycoprotein 1	carrier
Zolmitriptan	5-hydroxytryptamine receptor 1D	target
Zolmitriptan	5-hydroxytryptamine receptor 1B	target
Zolmitriptan	5-hydroxytryptamine receptor 1F	target
Zolmitriptan	Cytochrome P450 1A2	enzyme
Zolmitriptan	Amine oxidase [flavin-containing] A	enzyme
Zolmitriptan	5-hydroxytryptamine receptor 1A	target
Zolmitriptan	P-glycoprotein 1	transporter
Zolmitriptan	5-hydroxytryptamine receptor 7	target
Zolmitriptan	5-hydroxytryptamine receptor 2A	target
Zolmitriptan	5-hydroxytryptamine receptor 2B	target
Zolmitriptan	5-hydroxytryptamine receptor 1E	target
Amitriptyline	Sodium-dependent serotonin transporter	target
Amitriptyline	Sodium-dependent noradrenaline transporter	target
Amitriptyline	Potassium voltage-gated channel subfamily KQT member 2	target
Amitriptyline	Alpha-2A adrenergic receptor	target
Amitriptyline	Cytochrome P450 1A2	enzyme
Amitriptyline	Cytochrome P450 2C19	enzyme
Amitriptyline	Cytochrome P450 2D6	enzyme
Amitriptyline	Serum albumin	carrier
Amitriptyline	Alpha-1-acid glycoprotein 1	carrier
Amitriptyline	Histamine H1 receptor	target
Amitriptyline	5-hydroxytryptamine receptor 2A	target
Amitriptyline	5-hydroxytryptamine receptor 1A	target
Amitriptyline	Alpha-1A adrenergic receptor	target
Amitriptyline	Cytochrome P450 3A4	enzyme
Amitriptyline	Cytochrome P450 3A5	enzyme
Amitriptyline	Potassium voltage-gated channel subfamily A member 1	target
Amitriptyline	Alpha-1D adrenergic receptor	target
Amitriptyline	Delta-type opioid receptor	target
Amitriptyline	Kappa-type opioid receptor	target
Amitriptyline	High affinity nerve growth factor receptor	target
Amitriptyline	BDNF/NT-3 growth factors receptor	target
Amitriptyline	Cytochrome P450 2C9	enzyme
Amitriptyline	Cytochrome P450 2B6	enzyme
Amitriptyline	Cytochrome P450 2C8	enzyme
Amitriptyline	Histamine H2 receptor	target
Amitriptyline	Histamine H4 receptor	target
Amitriptyline	Sigma non-opioid intracellular receptor 1	target
Amitriptyline	5-hydroxytryptamine receptor 2C	target
Amitriptyline	Alpha-1B adrenergic receptor	target
Amitriptyline	5-hydroxytryptamine receptor 7	target
Amitriptyline	5-hydroxytryptamine receptor 1D	target
Amitriptyline	Mu-type opioid receptor	target
Amitriptyline	5-hydroxytryptamine receptor 1B	target
Amitriptyline	5-hydroxytryptamine receptor 6	target
Amitriptyline	Potassium voltage-gated channel subfamily KQT member 3	target
Amitriptyline	UDP-glucuronosyltransferase 2B10	enzyme
Amitriptyline	5-hydroxytryptamine receptor 1C	target
Amitriptyline	Muscarinic acetylcholine receptor	target
Amitriptyline	HERG human cardiac K+ channel	target
Amitriptyline	P-glycoprotein 1	transporter
Amitriptyline	UDP-glucuronosyltransferase 1-4	enzyme
Amitriptyline	Glutathione S-transferases (Cytosolic)	enzyme
Olanzapine	Dopamine D1 receptor	target
Olanzapine	Muscarinic acetylcholine receptor M1	target
Olanzapine	Muscarinic acetylcholine receptor M3	target
Olanzapine	5-hydroxytryptamine receptor 2A	target
Olanzapine	Dopamine D4 receptor	target
Olanzapine	Histamine H1 receptor	target
Olanzapine	Muscarinic acetylcholine receptor M4	target
Olanzapine	Muscarinic acetylcholine receptor M2	target
Olanzapine	Dopamine D2 receptor	target
Olanzapine	5-hydroxytryptamine receptor 2C	target
Olanzapine	Dopamine D3 receptor	target
Olanzapine	Alpha-1B adrenergic receptor	target
Olanzapine	Cytochrome P450 1A2	enzyme
Olanzapine	5-hydroxytryptamine receptor 3A	target
Olanzapine	5-hydroxytryptamine receptor 6	target
Olanzapine	Alpha-1A adrenergic receptor	target
Olanzapine	Dopamine D5 receptor	target
Olanzapine	Serum albumin	carrier
Olanzapine	Alpha-1-acid glycoprotein 1	carrier
Olanzapine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Olanzapine	Cytochrome P450 2D6	enzyme
Olanzapine	P-glycoprotein 1	transporter
Olanzapine	Cytochrome P450 2C19	enzyme
Olanzapine	D(1) dopamine receptor	target
Olanzapine	Beta adrenergic receptor	target
Olanzapine	5-hydroxytryptamine receptor 1	target
Olanzapine	GABA(A) Receptor Benzodiazepine Binding Site	target
Olanzapine	Cytochrome P450 2C9	enzyme
Olanzapine	UDP-glucuronosyltransferase 1-4	enzyme
Olanzapine	Cytochrome P450 3A4	enzyme
Olanzapine	Cytochrome P450 3A Subfamily	enzyme
Clozapine	Dopamine D4 receptor	target
Clozapine	Histamine H1 receptor	target
Clozapine	Dopamine D2 receptor	target
Clozapine	Neuron-specific vesicular protein calcyon	target
Clozapine	Histamine H4 receptor	target
Clozapine	5-hydroxytryptamine receptor 2A	target
Clozapine	5-hydroxytryptamine receptor 1A	target
Clozapine	5-hydroxytryptamine receptor 2C	target
Clozapine	Dopamine D1 receptor	target
Clozapine	Cytochrome P450 1A2	enzyme
Clozapine	Cytochrome P450 2D6	enzyme
Clozapine	Dopamine D3 receptor	target
Clozapine	Muscarinic acetylcholine receptor M1	target
Clozapine	Muscarinic acetylcholine receptor M2	target
Clozapine	Muscarinic acetylcholine receptor M3	target
Clozapine	Muscarinic acetylcholine receptor M4	target
Clozapine	Muscarinic acetylcholine receptor M5	target
Clozapine	5-hydroxytryptamine receptor 1B	target
Clozapine	5-hydroxytryptamine receptor 1D	target
Clozapine	5-hydroxytryptamine receptor 1E	target
Clozapine	5-hydroxytryptamine receptor 3A	target
Clozapine	5-hydroxytryptamine receptor 6	target
Clozapine	5-hydroxytryptamine receptor 7	target
Clozapine	Alpha-1A adrenergic receptor	target
Clozapine	Alpha-1B adrenergic receptor	target
Clozapine	Alpha-2A adrenergic receptor	target
Clozapine	Alpha-2B adrenergic receptor	target
Clozapine	Alpha-2C adrenergic receptor	target
Clozapine	Cytochrome P450 2C9	enzyme
Clozapine	P-glycoprotein 1	transporter
Clozapine	Cytochrome P450 3A4	enzyme
Clozapine	Cytochrome P450 2C19	enzyme
Clozapine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Clozapine	UDP-glucuronosyltransferase 1-4	enzyme
Clozapine	Cytochrome P450 1A1	enzyme
Clozapine	Cytochrome P450 2A6	enzyme
Clozapine	Cytochrome P450 2C8	enzyme
Clozapine	Glutathione S-transferase P	target
Clozapine	Alpha-1-acid glycoprotein 1	carrier
Clozapine	Serum albumin	carrier
Clozapine	Dopamine D5 receptor	target
Clozapine	Gamma-aminobutyric acid type B receptor subunit 1	target
Clozapine	Gamma-aminobutyric acid type B receptor subunit 2	target
Clozapine	Solute carrier family 22 member 1	transporter
Clozapine	Solute carrier family 22 member 2	transporter
Clozapine	Solute carrier family 22 member 3	transporter
Clozapine	Gamma-aminobutyric acid receptor subunit alpha-1	target
Clozapine	Gamma-aminobutyric acid receptor subunit beta-1	target
Clozapine	Gamma-aminobutyric acid receptor subunit gamma-1	target
Grepafloxacin	DNA gyrase subunit A	target
Grepafloxacin	DNA topoisomerase 4 subunit A	target
Grepafloxacin	Cytochrome P450 3A4	enzyme
Grepafloxacin	Cytochrome P450 1A2	enzyme
Grepafloxacin	Solute carrier family 22 member 2	transporter
Grepafloxacin	Solute carrier family 22 member 5	transporter
Grepafloxacin	Canalicular multispecific organic anion transporter 1	transporter
Grepafloxacin	P-glycoprotein 1	transporter
Grepafloxacin	Multidrug resistance-associated protein 1	transporter
Grepafloxacin	Solute carrier family 22 member 6	transporter
Mirtazapine	5-hydroxytryptamine receptor 2A	target
Mirtazapine	5HT3 serotonin receptor	target
Mirtazapine	Alpha-2A adrenergic receptor	target
Mirtazapine	5-hydroxytryptamine receptor 2C	target
Mirtazapine	Kappa-type opioid receptor	target
Mirtazapine	Histamine H1 receptor	target
Mirtazapine	Cytochrome P450 1A2	enzyme
Mirtazapine	Cytochrome P450 3A4	enzyme
Mirtazapine	Cytochrome P450 2D6	enzyme
Mirtazapine	Alpha-1 adrenergic receptors	target
Mirtazapine	Sodium-dependent serotonin transporter	transporter
Mexiletine	Sodium channel protein type 5 subunit alpha	target
Mexiletine	Cytochrome P450 1A2	enzyme
Mexiletine	Cytochrome P450 2D6	enzyme
Mexiletine	Cytochrome P450 2B6	enzyme
Mexiletine	Cytochrome P450 2E1	enzyme
Mexiletine	Cytochrome P450 3A4	enzyme
Mexiletine	Aryl hydrocarbon receptor	target
Tacrine	Acetylcholinesterase	target
Tacrine	Cytochrome P450 1A2	enzyme
Tacrine	Cholinesterase	target
Tacrine	P-glycoprotein 1	transporter
Tacrine	Liver carboxylesterase 1	target
Imipramine	Sodium-dependent noradrenaline transporter	target
Imipramine	Sodium-dependent serotonin transporter	target
Imipramine	Cytochrome P450 1A2	enzyme
Imipramine	Cytochrome P450 2C19	enzyme
Imipramine	Cytochrome P450 2D6	enzyme
Imipramine	Histamine H1 receptor	target
Imipramine	Alpha-1A adrenergic receptor	target
Imipramine	5-hydroxytryptamine receptor 2A	target
Imipramine	Muscarinic acetylcholine receptor M1	target
Imipramine	Muscarinic acetylcholine receptor M2	target
Imipramine	Muscarinic acetylcholine receptor M3	target
Imipramine	Muscarinic acetylcholine receptor M4	target
Imipramine	Muscarinic acetylcholine receptor M5	target
Imipramine	Potassium voltage-gated channel subfamily D member 2	target
Imipramine	Potassium voltage-gated channel subfamily D member 3	target
Imipramine	Alpha-1D adrenergic receptor	target
Imipramine	Alpha-1-acid glycoprotein 1	carrier
Imipramine	Solute carrier family 22 member 2	transporter
Imipramine	Solute carrier family 22 member 3	transporter
Imipramine	P-glycoprotein 1	transporter
Imipramine	Solute carrier family 22 member 4	transporter
Imipramine	Cytochrome P450 3A4	enzyme
Imipramine	Cytochrome P450 2B6	enzyme
Imipramine	Cytochrome P450 2C18	enzyme
Imipramine	Cytochrome P450 2E1	enzyme
Imipramine	Cytochrome P450 3A7	enzyme
Imipramine	5-hydroxytryptamine receptor 2C	target
Imipramine	Alpha-1B adrenergic receptor	target
Imipramine	5-hydroxytryptamine receptor 7	target
Imipramine	D(1) dopamine receptor	target
Imipramine	Dopamine D2 receptor	target
Imipramine	Potassium voltage-gated channel subfamily H member 2	target
Imipramine	Sodium-dependent dopamine transporter	target
Imipramine	5-hydroxytryptamine receptor 1A	target
Imipramine	5-hydroxytryptamine receptor 6	target
Imipramine	Potassium voltage-gated channel subfamily H member 1	target
Imipramine	Serum albumin	carrier
Imipramine	Alpha-1-acid glycoprotein 2	target
Duloxetine	Sodium-dependent serotonin transporter	target
Duloxetine	Sodium-dependent dopamine transporter	target
Duloxetine	Sodium-dependent noradrenaline transporter	target
Duloxetine	Cytochrome P450 1A2	enzyme
Duloxetine	Cytochrome P450 2D6	enzyme
Duloxetine	Cytochrome P450 2C9	enzyme
Duloxetine	Serum albumin	carrier
Duloxetine	alpha1-acid glycoprotein	carrier
Duloxetine	P-glycoprotein 1	transporter
Duloxetine	Cytochrome P450 3A4	enzyme
Duloxetine	Cytochrome P450 2B6	enzyme
Duloxetine	Cytochrome P450 2C19	enzyme
Flutamide	Androgen receptor	target
Flutamide	Cytochrome P450 1A2	enzyme
Flutamide	Cytochrome P450 3A4	enzyme
Flutamide	Cytochrome P450 1A1	enzyme
Flutamide	Cytochrome P450 1B1	enzyme
Flutamide	Cytochrome P450 3A5	enzyme
Flutamide	Aryl hydrocarbon receptor	target
Flutamide	Nuclear receptor subfamily 1 group I member 2	target
Flutamide	Multidrug resistance-associated protein 1	transporter
Haloperidol	Dopamine D2 receptor	target
Haloperidol	Glutamate receptor ionotropic, NMDA 2B	target
Haloperidol	Dopamine D1 receptor	target
Haloperidol	Cytochrome P450 1A2	enzyme
Haloperidol	Cytochrome P450 2D6	enzyme
Haloperidol	5-hydroxytryptamine receptor 2A	target
Haloperidol	Dopamine D3 receptor	target
Haloperidol	Cytochrome P450 3A4	enzyme
Haloperidol	Cytochrome P450 3A5	enzyme
Haloperidol	Cytochrome P450 3A7	enzyme
Haloperidol	P-glycoprotein 1	transporter
Haloperidol	Carbonyl reductase [NADPH] 1	enzyme
Haloperidol	UDP-glucuronosyltransferase 1-9	enzyme
Haloperidol	Cytochrome P450 2C19	enzyme
Haloperidol	Cytochrome P450 2C9	enzyme
Haloperidol	Melanin-concentrating hormone receptor 1	target
Haloperidol	Synaptic vesicular amine transporter	target
Haloperidol	5-hydroxytryptamine receptor 2C	target
Haloperidol	Sigma non-opioid intracellular receptor 1	target
Haloperidol	Histamine H1 receptor	target
Haloperidol	Muscarinic acetylcholine receptor M3	target
Haloperidol	Alpha-1A adrenergic receptor	target
Haloperidol	Alpha-2A adrenergic receptor	target
Haloperidol	Alpha-2B adrenergic receptor	target
Haloperidol	Alpha-2C adrenergic receptor	target
Haloperidol	5-hydroxytryptamine receptor 1A	target
Haloperidol	5-hydroxytryptamine receptor 6	target
Haloperidol	5-hydroxytryptamine receptor 7	target
Haloperidol	Cytochrome P450 1A1	enzyme
Nortriptyline	Sodium-dependent serotonin transporter	target
Nortriptyline	Sodium-dependent noradrenaline transporter	target
Nortriptyline	Cytochrome P450 1A2	enzyme
Nortriptyline	Cytochrome P450 2D6	enzyme
Nortriptyline	Serum albumin	carrier
Nortriptyline	Alpha-1-acid glycoprotein 1	carrier
Nortriptyline	Histamine H1 receptor	target
Nortriptyline	5-hydroxytryptamine receptor 2A	target
Nortriptyline	Alpha-1A adrenergic receptor	target
Nortriptyline	5-hydroxytryptamine receptor 1A	target
Nortriptyline	Cytochrome P450 3A4	enzyme
Nortriptyline	Cytochrome P450 3A5	enzyme
Nortriptyline	Alpha-1D adrenergic receptor	target
Nortriptyline	Cytochrome P450 2C19	enzyme
Nortriptyline	Cytochrome P450 2E1	enzyme
Nortriptyline	5-hydroxytryptamine receptor 2C	target
Nortriptyline	Alpha-1B adrenergic receptor	target
Nortriptyline	Alpha-2 adrenergic receptors	target
Nortriptyline	Beta adrenergic receptor	target
Nortriptyline	Dopamine D2 receptor	target
Nortriptyline	Sigma receptor	target
Nortriptyline	5-hydroxytryptamine receptor 1C	target
Nortriptyline	Sodium-dependent noradrenaline transporter	transporter
Nortriptyline	Muscarinic acetylcholine receptor	target
Nortriptyline	P-glycoprotein 1	transporter
Fluorouracil	Thymidylate synthase	target
Fluorouracil	Cytochrome P450 1A2	enzyme
Fluorouracil	Thymidine phosphorylase	enzyme
Fluorouracil	Serum albumin	carrier
Fluorouracil	Cytochrome P450 2C9	enzyme
Fluorouracil	Dihydropyrimidine dehydrogenase [NADP(+)]	enzyme
Fluorouracil	Uridine phosphorylase 1	enzyme
Fluorouracil	Uridine phosphorylase 2	enzyme
Fluorouracil	DNA	target
Fluorouracil	RNA	target
Fluorouracil	Cytochrome P450 2A6	enzyme
Fluorouracil	Cytochrome P450 2C8	enzyme
Fluorouracil	Methylenetetrahydrofolate reductase	enzyme
Fluorouracil	Thymidylate synthase	enzyme
Fluorouracil	Uridine 5'-monophosphate synthase	enzyme
Fluorouracil	Amidophosphoribosyltransferase	enzyme
Fluorouracil	Solute carrier family 22 member 7	transporter
Fluorouracil	Equilibrative nucleoside transporter 1	transporter
Fluorouracil	ATP-binding cassette sub-family G member 2	transporter
Fluorouracil	Canalicular multispecific organic anion transporter 2	transporter
Fluorouracil	Multidrug resistance-associated protein 4	transporter
Fluorouracil	Multidrug resistance-associated protein 5	transporter
Fluorouracil	Thyroxine-binding globulin	carrier
Propranolol	Beta-1 adrenergic receptor	target
Propranolol	Beta-2 adrenergic receptor	target
Propranolol	Beta-3 adrenergic receptor	target
Propranolol	5-hydroxytryptamine receptor 1A	target
Propranolol	5-hydroxytryptamine receptor 1B	target
Propranolol	Cytochrome P450 1A2	enzyme
Propranolol	Cytochrome P450 2D6	enzyme
Propranolol	Alpha-1-acid glycoprotein 1	carrier
Propranolol	Cytochrome P450 2C19	enzyme
Propranolol	Cytochrome P450 3A4	enzyme
Propranolol	Cytochrome P450 3A5	enzyme
Propranolol	Cytochrome P450 3A7	enzyme
Propranolol	Solute carrier family 22 member 2	transporter
Propranolol	P-glycoprotein 1	transporter
Propranolol	Cytochrome P450 1A1	enzyme
Propranolol	Amine oxidase [flavin-containing] A	enzyme
Propranolol	Serum albumin	carrier
Estrone	Estrogen receptor alpha	target
Estrone	Cytochrome P450 1A2	enzyme
Estrone	Cytochrome P450 1A1	enzyme
Estrone	Serum albumin	carrier
Estrone	Solute carrier organic anion transporter family member 2B1	transporter
Estrone	P-glycoprotein 1	transporter
Estrone	Solute carrier organic anion transporter family member 1A2	transporter
Estrone	ATP-binding cassette sub-family G member 2	transporter
Estrone	Solute carrier organic anion transporter family member 1B1	transporter
Estrone	Cytochrome P450 3A4	enzyme
Estrone	Cytochrome P450 1B1	enzyme
Estrone	Cytochrome P450 2B6	enzyme
Estrone	Cytochrome P450 2C9	enzyme
Estrone	Cytochrome P450 2E1	enzyme
Estrone	Cytochrome P450 3A5	enzyme
Estrone	Estrogen receptor beta	target
Estrone	Androgen receptor	target
Estrone	Cytochrome P450 19A1	target
Estrone	Sex hormone-binding globulin	target
Estrone	Solute carrier family 22 member 8	transporter
Verapamil	ATP-sensitive inward rectifier potassium channel 11	target
Verapamil	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Verapamil	Potassium voltage-gated channel subfamily H member 2	target
Verapamil	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Verapamil	Cytochrome P450 1A2	enzyme
Verapamil	Cytochrome P450 3A5	enzyme
Verapamil	Voltage-dependent N-type calcium channel subunit alpha-1B	target
Verapamil	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	target
Verapamil	Sodium-dependent serotonin transporter	target
Verapamil	Cytochrome P450 3A4	enzyme
Verapamil	P-glycoprotein 1	transporter
Verapamil	Solute carrier family 22 member 1	transporter
Verapamil	Canalicular multispecific organic anion transporter 2	transporter
Verapamil	Multidrug resistance-associated protein 4	transporter
Verapamil	Solute carrier family 22 member 5	transporter
Verapamil	Solute carrier organic anion transporter family member 1A2	transporter
Verapamil	Multidrug resistance-associated protein 7	transporter
Verapamil	Solute carrier family 22 member 4	transporter
Verapamil	Solute carrier organic anion transporter family member 1B1	transporter
Verapamil	Cytochrome P450 2C8	enzyme
Verapamil	Cytochrome P450 2C9	enzyme
Verapamil	Cytochrome P450 2B6	enzyme
Verapamil	Cytochrome P450 2C19	enzyme
Verapamil	Cytochrome P450 2D6	enzyme
Verapamil	Alpha-1A adrenergic receptor	target
Verapamil	Alpha-1B adrenergic receptor	target
Verapamil	Alpha-1D adrenergic receptor	target
Verapamil	Serum albumin	carrier
Verapamil	Alpha-1-acid glycoprotein 1	carrier
Verapamil	Cytochrome P450 2C18	enzyme
Verapamil	Cytochrome P450 2E1	enzyme
Verapamil	Multidrug resistance-associated protein 1	transporter
Verapamil	Multidrug and toxin extrusion protein 1	transporter
Verapamil	Multidrug and toxin extrusion protein 2	transporter
Verapamil	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Verapamil	Voltage-dependent calcium channel	target
Verapamil	P-glycoprotein 1	target
Warfarin	Vitamin K epoxide reductase complex subunit 1	target
Warfarin	Cytochrome P450 2C8	enzyme
Warfarin	Cytochrome P450 1A2	enzyme
Warfarin	Cytochrome P450 2C9	enzyme
Warfarin	Alpha-1-acid glycoprotein 1	carrier
Warfarin	Serum albumin	carrier
Warfarin	Cytochrome P450 2C19	enzyme
Warfarin	Cytochrome P450 3A4	enzyme
Warfarin	Cytochrome P450 2C18	enzyme
Warfarin	Nuclear receptor subfamily 1 group I member 2	target
Tizanidine	Alpha-2 adrenergic receptors	target
Tizanidine	Cytochrome P450 1A2	enzyme
Tizanidine	Nischarin	target
Tizanidine	Alpha-1 adrenergic receptors	target
Riluzole	Sodium channel protein type 5 subunit alpha	target
Riluzole	Cytochrome P450 1A2	enzyme
Riluzole	Cystine/glutamate transporter	target
Riluzole	ATP-binding cassette sub-family G member 2	transporter
Riluzole	Cytochrome P450 1A1	enzyme
Zileuton	Arachidonate 5-lipoxygenase	target
Zileuton	Cytochrome P450 2C9	enzyme
Zileuton	Cytochrome P450 1A2	enzyme
Zileuton	Cytochrome P450 3A4	enzyme
Zileuton	Prostaglandin G/H synthase 1	enzyme
Zileuton	UDP-glucuronosyltransferase 1-9	enzyme
Zileuton	Serum albumin	carrier
Estradiol	Estrogen receptor alpha	target
Estradiol	Nuclear receptor subfamily 1 group I member 2	target
Estradiol	Sex hormone-binding globulin	carrier
Estradiol	Estrogen receptor beta	target
Estradiol	Cytochrome P450 1A2	enzyme
Estradiol	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol	Serum albumin	carrier
Estradiol	Fatty acid-binding protein, intestinal	carrier
Estradiol	Cytochrome P450 3A4	enzyme
Estradiol	Cytochrome P450 3A5	enzyme
Estradiol	Cytochrome P450 3A7	enzyme
Estradiol	Solute carrier family 22 member 2	transporter
Estradiol	Solute carrier family 22 member 3	transporter
Estradiol	Multidrug resistance-associated protein 7	transporter
Estradiol	Solute carrier family 22 member 11	transporter
Estradiol	ATP-binding cassette sub-family G member 2	transporter
Estradiol	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol	P-glycoprotein 1	transporter
Estradiol	Cytochrome P450 1A1	enzyme
Estradiol	Cytochrome P450 1B1	enzyme
Estradiol	Cytochrome P450 2C19	enzyme
Estradiol	Cytochrome P450 2C8	enzyme
Estradiol	Cytochrome P450 2C9	enzyme
Estradiol	Solute carrier family 22 member 8	transporter
Estradiol	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol	G-protein coupled estrogen receptor 1	target
Estradiol	ATP synthase subunit a	target
Estradiol	Beclin-1	target
Estradiol	UDP-glucuronosyltransferase 2B15	enzyme
Estradiol	Catechol O-methyltransferase	enzyme
Estradiol	UDP-glucuronosyltransferases (UGTs)	enzyme
Estradiol	Cytochrome P450 19A1	enzyme
Dacarbazine	DNA polymerase alpha subunit B	target
Dacarbazine	Cytochrome P450 1A1	enzyme
Dacarbazine	Cytochrome P450 1A2	enzyme
Dacarbazine	Cytochrome P450 2E1	enzyme
Dacarbazine	6-phosphogluconate dehydrogenase, decarboxylating	target
Dacarbazine	DNA	target
Ondansetron	5-hydroxytryptamine receptor 3A	target
Ondansetron	Cytochrome P450 3A4	enzyme
Ondansetron	Cytochrome P450 1A2	enzyme
Ondansetron	Cytochrome P450 2D6	enzyme
Ondansetron	Cytochrome P450 3A5	enzyme
Ondansetron	Cytochrome P450 3A7	enzyme
Ondansetron	5-hydroxytryptamine receptor 4	target
Ondansetron	5-hydroxytryptamine receptor 1A	target
Ondansetron	5-hydroxytryptamine receptor 1B	target
Ondansetron	Mu-type opioid receptor	target
Ondansetron	Cytochrome P450 2C9	enzyme
Ondansetron	Cytochrome P450 2E1	enzyme
Cyclobenzaprine	5-hydroxytryptamine receptor 2A	target
Cyclobenzaprine	Cytochrome P450 1A2	enzyme
Cyclobenzaprine	Cytochrome P450 3A4	enzyme
Cyclobenzaprine	Cytochrome P450 2D6	enzyme
Cyclobenzaprine	Serum albumin	carrier
Cyclobenzaprine	UDP-glucuronosyltransferase 1-4	enzyme
Cyclobenzaprine	UDP-glucuronosyltransferase 2B10	enzyme
Cyclobenzaprine	5-hydroxytryptamine receptor 2B	target
Cyclobenzaprine	5-hydroxytryptamine receptor 2C	target
Cyclobenzaprine	5-hydroxytryptamine receptor 7	target
Cyclobenzaprine	5-hydroxytryptamine receptor 6	target
Cyclobenzaprine	Sodium-dependent serotonin transporter	target
Cyclobenzaprine	Sodium-dependent noradrenaline transporter	target
Cyclobenzaprine	Toll-like receptor 4	target
Cyclobenzaprine	Aldehyde oxidase	target
Ramelteon	Melatonin receptor type 1B	target
Ramelteon	Melatonin receptor type 1A	target
Ramelteon	Cytochrome P450 1A2	enzyme
Ramelteon	Cytochrome P450 2C19	enzyme
Ramelteon	Cytochrome P450 3A4	enzyme
Ramelteon	Cytochrome P450 2C9	enzyme
Frovatriptan	5-hydroxytryptamine receptor 1D	target
Frovatriptan	5-hydroxytryptamine receptor 1B	target
Frovatriptan	Cytochrome P450 1A2	enzyme
Levobupivacaine	Sodium channel protein type 10 subunit alpha	target
Levobupivacaine	Cytochrome P450 3A4	enzyme
Levobupivacaine	Cytochrome P450 1A2	enzyme
Cinacalcet	Extracellular calcium-sensing receptor	target
Cinacalcet	Cytochrome P450 3A4	enzyme
Cinacalcet	Cytochrome P450 2D6	enzyme
Cinacalcet	Cytochrome P450 1A2	enzyme
Pimozide	Dopamine D2 receptor	target
Pimozide	Calmodulin	target
Pimozide	Potassium voltage-gated channel subfamily H member 2	target
Pimozide	Cytochrome P450 3A4	enzyme
Pimozide	Cytochrome P450 1A2	enzyme
Pimozide	Cytochrome P450 3A5	enzyme
Pimozide	Cytochrome P450 3A7	enzyme
Pimozide	P-glycoprotein 1	transporter
Pimozide	Dopamine D3 receptor	target
Pimozide	Cytochrome P450 2D6	enzyme
Propafenone	Sodium channel protein type 5 subunit alpha	target
Propafenone	Potassium voltage-gated channel subfamily H member 2	target
Propafenone	Cytochrome P450 1A2	enzyme
Propafenone	Cytochrome P450 2D6	enzyme
Propafenone	Cytochrome P450 3A4	enzyme
Propafenone	P-glycoprotein 1	transporter
Propafenone	Beta-1 adrenergic receptor	target
Propafenone	Beta-2 adrenergic receptor	target
Clomipramine	Sodium-dependent serotonin transporter	target
Clomipramine	Sodium-dependent noradrenaline transporter	target
Clomipramine	Glutathione S-transferase P	target
Clomipramine	5-hydroxytryptamine receptor 2A	target
Clomipramine	Cytochrome P450 1A2	enzyme
Clomipramine	Cytochrome P450 2D6	enzyme
Clomipramine	Cytochrome P450 2C19	enzyme
Clomipramine	P-glycoprotein 1	transporter
Clomipramine	Cytochrome P450 3A4	enzyme
Clomipramine	5-hydroxytryptamine receptor 2B	target
Clomipramine	5-hydroxytryptamine receptor 2C	target
Clomipramine	Serum albumin	carrier
Rasagiline	Apoptosis regulator Bcl-2	target
Rasagiline	Amine oxidase [flavin-containing] B	target
Rasagiline	Cytochrome P450 1A2	enzyme
Chlorzoxazone	Calcium-activated potassium channel subunit alpha-1	target
Chlorzoxazone	Cytochrome P450 2E1	enzyme
Chlorzoxazone	Cytochrome P450 1A2	enzyme
Chlorzoxazone	Cytochrome P450 2A6	enzyme
Chlorzoxazone	Cytochrome P450 1A1	enzyme
Chlorzoxazone	Cytochrome P450 2D6	enzyme
Chlorzoxazone	Cytochrome P450 3A4	enzyme
Chlorpromazine	Dopamine D2 receptor	target
Chlorpromazine	5-hydroxytryptamine receptor 2A	target
Chlorpromazine	Cytochrome P450 2D6	enzyme
Chlorpromazine	Cholinesterase	enzyme
Chlorpromazine	Cytochrome P450 1A2	enzyme
Chlorpromazine	Serum albumin	carrier
Chlorpromazine	P-glycoprotein 1	transporter
Chlorpromazine	Dopamine D1 receptor	target
Chlorpromazine	5-hydroxytryptamine receptor 1A	target
Chlorpromazine	Alpha-1A adrenergic receptor	target
Chlorpromazine	Alpha-1B adrenergic receptor	target
Chlorpromazine	Cytochrome P450 2E1	enzyme
Chlorpromazine	Cytochrome P450 3A4	enzyme
Chlorpromazine	Histamine H1 receptor	target
Chlorpromazine	Potassium voltage-gated channel subfamily H member 2	target
Chlorpromazine	D(1) dopamine receptor	target
Chlorpromazine	Dopamine D3 receptor	target
Chlorpromazine	Dopamine D4 receptor	target
Chlorpromazine	Dopamine D5 receptor	target
Chlorpromazine	5-hydroxytryptamine receptor 2C	target
Chlorpromazine	5-hydroxytryptamine 2 receptor	target
Chlorpromazine	Alpha-1 adrenergic receptors	target
Chlorpromazine	Alpha-2 adrenergic receptors	target
Chlorpromazine	Muscarinic acetylcholine receptor M1	target
Chlorpromazine	Muscarinic acetylcholine receptor M3	target
Chlorpromazine	Sphingomyelin phosphodiesterase	target
Chlorpromazine	Calmodulin	target
Chlorpromazine	alpha1-acid glycoprotein	target
Chlorpromazine	5-hydroxytryptamine receptor 6	target
Chlorpromazine	5-hydroxytryptamine receptor 7	target
Chlorpromazine	Histamine H4 receptor	target
Chlorpromazine	Bile salt export pump	transporter
Mephenytoin	Sodium channel protein type 5 subunit alpha	target
Mephenytoin	Cytochrome P450 2B6	enzyme
Mephenytoin	Cytochrome P450 2C9	enzyme
Mephenytoin	Cytochrome P450 2C19	enzyme
Mephenytoin	Cytochrome P450 1A2	enzyme
Mephenytoin	Cytochrome P450 2D6	enzyme
Mephenytoin	Cytochrome P450 2C8	enzyme
Mephenytoin	Nuclear receptor subfamily 1 group I member 2	target
Mephenytoin	Thyroxine-binding globulin	carrier
Diclofenac	Prostaglandin G/H synthase 1	target
Diclofenac	Prostaglandin G/H synthase 2	target
Diclofenac	Transthyretin	carrier
Diclofenac	Cytochrome P450 2C9	enzyme
Diclofenac	Cytochrome P450 2C19	enzyme
Diclofenac	Cytochrome P450 1A2	enzyme
Diclofenac	Cytochrome P450 2C8	enzyme
Diclofenac	Serum albumin	carrier
Diclofenac	Multidrug resistance-associated protein 4	transporter
Diclofenac	Multidrug resistance-associated protein 1	transporter
Diclofenac	Solute carrier family 22 member 6	transporter
Diclofenac	Solute carrier family 22 member 8	transporter
Diclofenac	Solute carrier organic anion transporter family member 1C1	transporter
Diclofenac	Solute carrier family 22 member 11	transporter
Diclofenac	UDP-glucuronosyltransferase 2B7	enzyme
Diclofenac	Cytochrome P450 3A4	enzyme
Diclofenac	Cytochrome P450 2B6	enzyme
Diclofenac	Cytochrome P450 2C18	enzyme
Diclofenac	Cytochrome P450 2E1	enzyme
Diclofenac	Solute carrier organic anion transporter family member 1B1	transporter
Diclofenac	Bile salt export pump	transporter
Diclofenac	UDP-glucuronosyltransferase 1-3	enzyme
Diclofenac	UDP-glucuronosyltransferase 1-9	enzyme
Diclofenac	UDP-glucuronosyltransferase 2B4	enzyme
Diclofenac	Arachidonate 5-lipoxygenase	enzyme
Diclofenac	Sodium channel protein type 4 subunit alpha	transporter
Diclofenac	Acid-sensing ion channel 1	transporter
Diclofenac	Potassium voltage-gated channel subfamily KQT member 2	transporter
Diclofenac	Potassium voltage-gated channel subfamily KQT member 3	transporter
Diclofenac	Phospholipase A2, membrane associated	enzyme
Diclofenac	P-glycoprotein 1	transporter
Azelastine	Histamine H1 receptor	target
Azelastine	Cytochrome P450 1A2	enzyme
Azelastine	Cytochrome P450 2D6	enzyme
Azelastine	Cytochrome P450 3A4	enzyme
Azelastine	Cytochrome P450 2C19	enzyme
Azelastine	Cytochrome P450 1A1	enzyme
Azelastine	Cytochrome P450 3A5	enzyme
Azelastine	Cytochrome P450 2C9	enzyme
Azelastine	Cytochrome P450 2C8	enzyme
Azelastine	P-glycoprotein 1	transporter
Azelastine	Cytochrome P450 2A6	enzyme
Azelastine	Cytochrome P450 2E1	enzyme
Azelastine	Histamine H2 receptor	target
Azelastine	Phospholipase A2	target
Azelastine	Leukotriene C4 synthase	target
Azelastine	Cytochrome P450 2B6	enzyme
Acenocoumarol	Vitamin K epoxide reductase complex subunit 1	target
Acenocoumarol	Cytochrome P450 2C9	enzyme
Acenocoumarol	Cytochrome P450 1A2	enzyme
Acenocoumarol	Serum albumin	carrier
Acenocoumarol	Alpha-1-acid glycoprotein 1	carrier
Acenocoumarol	Cytochrome P450 2C19	enzyme
Acenocoumarol	Cytochrome P450 3A4	enzyme
Acenocoumarol	P-glycoprotein 1	transporter
Aminophenazone	Cytochrome P450 2C19	enzyme
Aminophenazone	Cytochrome P450 1A2	enzyme
Aminophenazone	Cytochrome P450 2C8	enzyme
Aminophenazone	Solute carrier family 22 member 6	transporter
Aminophenazone	Cytochrome P450 2C9	enzyme
Aminophenazone	Cytochrome P450 2D6	enzyme
Aminophenazone	Cytochrome P450 3A4	enzyme
Aminophenazone	Cytochrome P450 2C18	enzyme
Aminophenazone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Palonosetron	5-hydroxytryptamine receptor 3A	target
Palonosetron	Cytochrome P450 2D6	enzyme
Palonosetron	Cytochrome P450 3A4	enzyme
Palonosetron	Cytochrome P450 1A2	enzyme
Melatonin	Acetylserotonin O-methyltransferase	target
Melatonin	Melatonin receptor type 1A	target
Melatonin	Melatonin receptor type 1B	target
Melatonin	Nuclear receptor ROR-beta	target
Melatonin	Calmodulin	target
Melatonin	Calreticulin	target
Melatonin	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Melatonin	Myeloperoxidase	target
Melatonin	Estrogen receptor alpha	target
Melatonin	Eosinophil peroxidase	target
Melatonin	Cytochrome P450 1A1	enzyme
Melatonin	Cytochrome P450 1A2	enzyme
Melatonin	Cytochrome P450 2C19	enzyme
Melatonin	Cytochrome P450 2C9	enzyme
Melatonin	Acetylserotonin O-methyltransferase	enzyme
Melatonin	Indoleamine 2,3-dioxygenase 1	enzyme
Melatonin	Myeloperoxidase	enzyme
Melatonin	Cytochrome P450 1B1	enzyme
Melatonin	Solute carrier family 22 member 8	transporter
Melatonin	Cytochrome P450 19A1	enzyme
Imatinib	Platelet-derived growth factor receptor beta	target
Imatinib	Tyrosine-protein kinase ABL1	target
Imatinib	Mast/stem cell growth factor receptor Kit	target
Imatinib	RET proto-oncogene	target
Imatinib	High affinity nerve growth factor receptor	target
Imatinib	Macrophage colony-stimulating factor 1 receptor	target
Imatinib	Platelet-derived growth factor receptor alpha	target
Imatinib	Epithelial discoidin domain-containing receptor 1	target
Imatinib	Cytochrome P450 3A4	enzyme
Imatinib	Breakpoint cluster region protein	target
Imatinib	Cytochrome P450 1A2	enzyme
Imatinib	Cytochrome P450 2D6	enzyme
Imatinib	Cytochrome P450 2C9	enzyme
Imatinib	Cytochrome P450 2C19	enzyme
Imatinib	Cytochrome P450 3A5	enzyme
Imatinib	Cytochrome P450 3A7	enzyme
Imatinib	Solute carrier family 22 member 1	transporter
Imatinib	P-glycoprotein 1	transporter
Imatinib	Solute carrier family 22 member 2	transporter
Imatinib	ATP-binding cassette sub-family G member 2	transporter
Imatinib	ATP-binding cassette sub-family A member 3	transporter
Imatinib	Serum albumin	carrier
Imatinib	Alpha-1-acid glycoprotein 1	carrier
Imatinib	Bile salt export pump	transporter
Imatinib	Cytochrome P450 2C8	enzyme
Imatinib	Canalicular multispecific organic anion transporter 1	transporter
Imatinib	Multidrug resistance-associated protein 1	transporter
Imatinib	Solute carrier family 22 member 5	transporter
Imatinib	Solute carrier organic anion transporter family member 1B3	transporter
Imatinib	Multidrug resistance-associated protein 4	transporter
Imatinib	Solute carrier organic anion transporter family member 1A2	transporter
Imatinib	Discoidin domain-containing receptor 2	target
Quinine	Platelet glycoprotein IX	target
Quinine	Intermediate conductance calcium-activated potassium channel protein 4	target
Quinine	Cytochrome P450 3A4	enzyme
Quinine	Cytochrome P450 3A5	enzyme
Quinine	Cytochrome P450 1A1	enzyme
Quinine	Cytochrome P450 2D6	enzyme
Quinine	Cytochrome P450 1A2	enzyme
Quinine	Cytochrome P450 2C8	enzyme
Quinine	Cytochrome P450 2C9	enzyme
Quinine	Cytochrome P450 2C19	enzyme
Quinine	Cytochrome P450 2E1	enzyme
Quinine	Cytochrome P450 3A7	enzyme
Quinine	Solute carrier family 22 member 2	transporter
Quinine	Solute carrier family 22 member 1	transporter
Quinine	Solute carrier family 22 member 5	transporter
Quinine	P-glycoprotein 1	transporter
Quinine	Solute carrier organic anion transporter family member 1A2	transporter
Quinine	Solute carrier family 22 member 4	transporter
Quinine	Fe(II)-protoporphyrin IX	target
Quinine	Solute carrier organic anion transporter family member 1B1	transporter
Doxepin	Sodium-dependent serotonin transporter	target
Doxepin	Sodium-dependent noradrenaline transporter	target
Doxepin	Histamine H1 receptor	target
Doxepin	Histamine H2 receptor	target
Doxepin	Cytochrome P450 2D6	enzyme
Doxepin	Muscarinic acetylcholine receptor M1	target
Doxepin	Muscarinic acetylcholine receptor M2	target
Doxepin	Muscarinic acetylcholine receptor M3	target
Doxepin	Muscarinic acetylcholine receptor M4	target
Doxepin	Muscarinic acetylcholine receptor M5	target
Doxepin	Alpha-1A adrenergic receptor	target
Doxepin	5-hydroxytryptamine receptor 1A	target
Doxepin	5-hydroxytryptamine receptor 2A	target
Doxepin	Cytochrome P450 2C19	enzyme
Doxepin	Cytochrome P450 2C9	enzyme
Doxepin	Cytochrome P450 1A2	enzyme
Doxepin	P-glycoprotein 1	transporter
Doxepin	5-hydroxytryptamine receptor 2B	target
Doxepin	5-hydroxytryptamine receptor 2C	target
Doxepin	Alpha-1B adrenergic receptor	target
Doxepin	Alpha-1D adrenergic receptor	target
Doxepin	Cytochrome P450 3A4	enzyme
Doxepin	5-hydroxytryptamine receptor 6	target
Doxepin	Histamine H4 receptor	target
Doxepin	Potassium voltage-gated channel subfamily H member 2	target
Doxepin	Serum albumin	carrier
Doxepin	Alpha-1-acid glycoprotein 1	carrier
Carbamazepine	Voltage-gated sodium channel alpha subunit	target
Carbamazepine	Cytochrome P450 2C8	enzyme
Carbamazepine	Cytochrome P450 2B6	enzyme
Carbamazepine	Cytochrome P450 3A4	enzyme
Carbamazepine	Cytochrome P450 1A2	enzyme
Carbamazepine	Cytochrome P450 2C19	enzyme
Carbamazepine	Cytochrome P450 2C9	enzyme
Carbamazepine	P-glycoprotein 1	transporter
Carbamazepine	Cytochrome P450 3A5	enzyme
Carbamazepine	UDP-glucuronosyltransferase 2B7	enzyme
Carbamazepine	RalA-binding protein 1	transporter
Carbamazepine	Canalicular multispecific organic anion transporter 1	transporter
Carbamazepine	Neuronal acetylcholine receptor subunit alpha-4	target
Carbamazepine	Nuclear receptor subfamily 1 group I member 2	target
Carbamazepine	UDP-glucuronosyltransferase 1-1	enzyme
Carbamazepine	UDP-glucuronosyltransferase 1-6	enzyme
Carbamazepine	UDP-glucuronosyltransferase 1-7	enzyme
Zolpidem	Gamma-aminobutyric acid receptor subunit alpha-1	target
Zolpidem	Cytochrome P450 3A4	enzyme
Zolpidem	Cytochrome P450 1A2	enzyme
Zolpidem	Gamma-aminobutyric acid receptor subunit alpha-2	target
Zolpidem	Gamma-aminobutyric acid receptor subunit alpha-3	target
Zolpidem	Cytochrome P450 2C9	enzyme
Zolpidem	Cytochrome P450 2C19	enzyme
Zolpidem	Cytochrome P450 2D6	enzyme
Zolpidem	Gamma-aminobutyric acid receptor subunit gamma-2	target
Fluoxetine	Sodium-dependent serotonin transporter	target
Fluoxetine	Cytochrome P450 2C9	enzyme
Fluoxetine	Cytochrome P450 2D6	enzyme
Fluoxetine	CYP2B protein	enzyme
Fluoxetine	Cytochrome P450 1A2	enzyme
Fluoxetine	Cytochrome P450 3A4	enzyme
Fluoxetine	Cytochrome P450 2C19	enzyme
Fluoxetine	P-glycoprotein 1	transporter
Fluoxetine	Cytochrome P450 2B6	enzyme
Fluoxetine	Cytochrome P450 3A5	enzyme
Fluoxetine	Serum albumin	carrier
Fluoxetine	Alpha-1-acid glycoprotein 1	carrier
Fluoxetine	Potassium voltage-gated channel subfamily H member 2	target
Fluoxetine	5-hydroxytryptamine receptor 2C	target
Fluoxetine	Cyclin-dependent kinases regulatory subunit 1	target
Fluoxetine	Neuronal acetylcholine receptor subunit alpha-2	target
Fluoxetine	Neuronal acetylcholine receptor subunit alpha-3	target
Fluoxetine	Neuronal acetylcholine receptor subunit beta-4	target
Antipyrine	Cytochrome P450 2C8	enzyme
Antipyrine	Cytochrome P450 2C9	enzyme
Antipyrine	Cytochrome P450 1A2	enzyme
Antipyrine	Cytochrome P450 2C19	enzyme
Antipyrine	Cytochrome P450 3A4	enzyme
Antipyrine	Solute carrier family 22 member 6	transporter
Antipyrine	Cytochrome P450 2A6	enzyme
Antipyrine	Cytochrome P450 2B6	enzyme
Antipyrine	Cytochrome P450 2C18	enzyme
Antipyrine	Cytochrome P450 2D6	enzyme
Antipyrine	Cytochrome P450 2E1	enzyme
Antipyrine	Prostaglandin G/H synthase 2	target
Antipyrine	Prostaglandin G/H synthase 1	target
Terbinafine	Squalene monooxygenase	target
Terbinafine	Cytochrome P450 2D6	enzyme
Terbinafine	Cytochrome P450 2C9	enzyme
Terbinafine	Cytochrome P450 1A2	enzyme
Terbinafine	Cytochrome P450 3A4	enzyme
Terbinafine	Cytochrome P450 2C8	enzyme
Terbinafine	Cytochrome P450 2C19	enzyme
Terbinafine	Prostaglandin G/H synthase 1	enzyme
Terbinafine	Serum albumin	carrier
Terbinafine	alpha1-acid glycoprotein	carrier
Terbinafine	ABC multidrug transporter MDR2	transporter
Terbinafine	Squalene monooxygenase	target
Cinnarizine	Histamine H1 receptor	target
Cinnarizine	Dopamine D2 receptor	target
Cinnarizine	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Cinnarizine	Cytochrome P450 2D6	enzyme
Cinnarizine	Cytochrome P450 2B6	enzyme
Cinnarizine	Cytochrome P450 2C9	enzyme
Cinnarizine	Cytochrome P450 1A1	enzyme
Cinnarizine	Cytochrome P450 1A2	enzyme
Cinnarizine	Cytochrome P450 2A6	enzyme
Cinnarizine	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Cinnarizine	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Cinnarizine	Voltage-dependent L-type calcium channel subunit alpha-1F	target
Cinnarizine	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Cinnarizine	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Cinnarizine	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Cinnarizine	D(1) dopamine receptor	target
Cinnarizine	Muscarinic acetylcholine receptor	target
Cinnarizine	Cytochrome P450 3A4	enzyme
Cinnarizine	Serum albumin	carrier
Flunarizine	Histamine H1 receptor	target
Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Flunarizine	Calmodulin	target
Flunarizine	Cytochrome P450 2D6	enzyme
Flunarizine	Cytochrome P450 2C9	enzyme
Flunarizine	Cytochrome P450 1A1	enzyme
Flunarizine	Cytochrome P450 1A2	enzyme
Flunarizine	Cytochrome P450 2A6	enzyme
Flunarizine	Cytochrome P450 3A4	enzyme
Naproxen	Prostaglandin G/H synthase 1	target
Naproxen	Prostaglandin G/H synthase 2	target
Naproxen	Serum albumin	carrier
Naproxen	Cytochrome P450 2C9	enzyme
Naproxen	Cytochrome P450 1A2	enzyme
Naproxen	Solute carrier organic anion transporter family member 1A2	transporter
Naproxen	Solute carrier family 22 member 6	transporter
Naproxen	Cytochrome P450 2C8	enzyme
Naproxen	UDP-glucuronosyltransferase 2B7	enzyme
Naproxen	Peptostreptococcal albumin-binding protein	target
Naproxen	Bile salt export pump	transporter
Naproxen	P-glycoprotein 1	transporter
Naproxen	UDP-glucuronosyltransferase 1-3	enzyme
Naproxen	UDP-glucuronosyltransferase 1-6	enzyme
Naproxen	UDP-glucuronosyltransferase 1-7	enzyme
Naproxen	UDP-glucuronosyltransferase 1-8	enzyme
Naproxen	UDP-glucuronosyltransferase 1-9	enzyme
Naproxen	UDP-glucuronosyltransferase 1-10	enzyme
Naproxen	Solute carrier family 22 member 8	transporter
Phenacetin	Prostaglandin G/H synthase 1	target
Phenacetin	Cytochrome P450 1A2	enzyme
Phenacetin	Cytochrome P450 2D6	enzyme
Phenacetin	Solute carrier family 22 member 6	transporter
Phenacetin	Cytochrome P450 1A1	enzyme
Phenacetin	Cytochrome P450 2A13	enzyme
Phenacetin	Cytochrome P450 2A6	enzyme
Phenacetin	Cytochrome P450 2C19	enzyme
Phenacetin	Cytochrome P450 2C9	enzyme
Phenacetin	Cytochrome P450 2E1	enzyme
Phenacetin	Cytochrome P450 3A4	enzyme
Aminophylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Aminophylline	Adenosine receptor A3	target
Aminophylline	Adenosine receptor A1	target
Aminophylline	Cytochrome P450 1A2	enzyme
Aminophylline	Cytochrome P450 2E1	enzyme
Aminophylline	Cytochrome P450 3A4	enzyme
Aminophylline	Histone deacetylase 2	target
Asenapine	5-hydroxytryptamine receptor 1A	target
Asenapine	5-hydroxytryptamine receptor 1B	target
Asenapine	5-hydroxytryptamine receptor 2A	target
Asenapine	5-hydroxytryptamine receptor 2B	target
Asenapine	5-hydroxytryptamine receptor 2C	target
Asenapine	5-hydroxytryptamine receptor 6	target
Asenapine	5-hydroxytryptamine receptor 7	target
Asenapine	Alpha-2A adrenergic receptor	target
Asenapine	Alpha-2B adrenergic receptor	target
Asenapine	Alpha-2C adrenergic receptor	target
Asenapine	Alpha-1A adrenergic receptor	target
Asenapine	Dopamine D1 receptor	target
Asenapine	Dopamine D2 receptor	target
Asenapine	Dopamine D3 receptor	target
Asenapine	Dopamine D4 receptor	target
Asenapine	Histamine H1 receptor	target
Asenapine	Histamine H2 receptor	target
Asenapine	Cytochrome P450 1A2	enzyme
Asenapine	Cytochrome P450 2D6	enzyme
Asenapine	5-hydroxytryptamine receptor 5A	target
Asenapine	UDP-glucuronosyltransferase 1-4	enzyme
Asenapine	Cytochrome P450 3A4	enzyme
Asenapine	Beta-1 adrenergic receptor	target
Asenapine	Beta-2 adrenergic receptor	target
Asenapine	Serum albumin	carrier
Asenapine	alpha1-acid glycoprotein	carrier
Betaxolol	Beta-1 adrenergic receptor	target
Betaxolol	Beta-2 adrenergic receptor	target
Betaxolol	Cytochrome P450 1A2	enzyme
Betaxolol	Cytochrome P450 2D6	enzyme
Estrone sulfate	Cytochrome P450 1A2	enzyme
Estrone sulfate	Cytochrome P450 3A4	enzyme
Estrone sulfate	Estrogen receptor alpha	target
Estrone sulfate	Estrogen receptor beta	target
Estrone sulfate	Sex hormone-binding globulin	carrier
Estrone sulfate	Serum albumin	carrier
Estrone sulfate	Cytochrome P450 2C9	enzyme
Estrone sulfate	Multidrug and toxin extrusion protein 1	transporter
Estrone sulfate	Multidrug and toxin extrusion protein 2	transporter
Estrone sulfate	Sodium/bile acid cotransporter	transporter
Guanabenz	Alpha-2A adrenergic receptor	target
Guanabenz	Cytochrome P450 1A2	enzyme
Guanabenz	Alpha-2B adrenergic receptor	target
Thiothixene	Cytochrome P450 1A2	enzyme
Thiothixene	Cytochrome P450 2D6	enzyme
Thiothixene	Dopamine D2 receptor	target
Thiothixene	Dopamine D1 receptor	target
Thiothixene	5-hydroxytryptamine receptor 2A	target
Thiothixene	Solute carrier family 22 member 1	transporter
Thiothixene	Serum albumin	carrier
Trifluoperazine	Dopamine D2 receptor	target
Trifluoperazine	Alpha-1A adrenergic receptor	target
Trifluoperazine	Neuron-specific vesicular protein calcyon	target
Trifluoperazine	Xanthine dehydrogenase/oxidase	enzyme
Trifluoperazine	UDP-glucuronosyltransferase 1-4	enzyme
Trifluoperazine	Cytochrome P450 1A2	enzyme
Trifluoperazine	P-glycoprotein 1	transporter
Trifluoperazine	Calmodulin	target
Trifluoperazine	Troponin C, slow skeletal and cardiac muscles	target
Trifluoperazine	Protein S100-A4	target
Promazine	Dopamine D2 receptor	target
Promazine	5-hydroxytryptamine receptor 2A	target
Promazine	5-hydroxytryptamine receptor 2C	target
Promazine	Alpha-1A adrenergic receptor	target
Promazine	Muscarinic acetylcholine receptor M1	target
Promazine	Histamine H1 receptor	target
Promazine	Cytochrome P450 2C19	enzyme
Promazine	Cytochrome P450 1A2	enzyme
Promazine	Cytochrome P450 3A4	enzyme
Promazine	Cytochrome P450 2C9	enzyme
Promazine	Cytochrome P450 2D6	enzyme
Carvedilol	Alpha-1A adrenergic receptor	target
Carvedilol	Beta-1 adrenergic receptor	target
Carvedilol	NADH dehydrogenase [ubiquinone] 1 subunit C2	target
Carvedilol	Beta-2 adrenergic receptor	target
Carvedilol	Vascular endothelial growth factor A	target
Carvedilol	Natriuretic peptides B	target
Carvedilol	Gap junction alpha-1 protein	target
Carvedilol	Potassium voltage-gated channel subfamily H member 2	target
Carvedilol	Vascular cell adhesion protein 1	target
Carvedilol	Cytochrome P450 2C9	enzyme
Carvedilol	Cytochrome P450 2D6	enzyme
Carvedilol	Xanthine dehydrogenase/oxidase	enzyme
Carvedilol	P-glycoprotein 1	transporter
Carvedilol	Cytochrome P450 1A2	enzyme
Carvedilol	Cytochrome P450 3A4	enzyme
Carvedilol	Cytochrome P450 1A1	enzyme
Carvedilol	Cytochrome P450 2E1	enzyme
Carvedilol	Alpha-1D adrenergic receptor	target
Carvedilol	Alpha-1B adrenergic receptor	target
Carvedilol	Alpha-2C adrenergic receptor	target
Carvedilol	Alpha-2B adrenergic receptor	target
Carvedilol	Alpha-2A adrenergic receptor	target
Carvedilol	E-selectin	target
Carvedilol	Hypoxia-inducible factor 1-alpha	target
Carvedilol	Inward rectifier potassium channel 4	target
Carvedilol	UDP-glucuronosyltransferase 1-1	enzyme
Carvedilol	Serum albumin	carrier
Carvedilol	UDP-glucuronosyltransferase 2B4	enzyme
Carvedilol	UDP-glucuronosyltransferase 2B7	enzyme
Carvedilol	Inward rectifier potassium channel 2	target
Carvedilol	Alpha-1 adrenergic receptors	target
Genistein	Estrogen receptor beta	target
Genistein	DNA topoisomerase 2-alpha	target
Genistein	Protein-tyrosine kinase 2-beta	target
Genistein	P-glycoprotein 1	transporter
Genistein	Multidrug resistance-associated protein 1	transporter
Genistein	ATP-binding cassette sub-family G member 2	transporter
Genistein	Cytochrome P450 1A2	enzyme
Genistein	Nuclear receptor coactivator 1	target
Genistein	Estrogen receptor alpha	target
Genistein	Nuclear receptor coactivator 2	target
Genistein	Transthyretin	carrier
Genistein	Steroid hormone receptor ERR2	target
Genistein	Steroid hormone receptor ERR1	target
Genistein	Nuclear receptor subfamily 1 group I member 2	target
Genistein	RAC-alpha serine/threonine-protein kinase	target
Genistein	G-protein coupled estrogen receptor 1	target
Genistein	Cytochrome P450 1B1	target
Genistein	Sex hormone-binding globulin	target
Genistein	Cytochrome P450 1A1	enzyme
Genistein	Solute carrier organic anion transporter family member 1B1	transporter
Genistein	Solute carrier organic anion transporter family member 2B1	transporter
Genistein	Cytochrome P450 2C8	enzyme
Genistein	Cytochrome P450 2C9	enzyme
Genistein	Cytochrome P450 3A1	enzyme
Genistein	Cytochrome P450 3A2	enzyme
Genistein	Cytochrome P450 3A4	enzyme
Genistein	Cystic fibrosis transmembrane conductance regulator	target
Resveratrol	Transthyretin	carrier
Resveratrol	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Resveratrol	Prostaglandin G/H synthase 1	target
Resveratrol	Casein kinase II subunit alpha	target
Resveratrol	Prostaglandin G/H synthase 2	target
Resveratrol	NAD-dependent protein deacetylase sirtuin-1	target
Resveratrol	Cytochrome P450 1A1	enzyme
Resveratrol	Cytochrome P450 3A4	enzyme
Resveratrol	Cytochrome P450 1A2	enzyme
Resveratrol	Cytochrome P450 1B1	enzyme
Resveratrol	Arachidonate 15-lipoxygenase	target
Resveratrol	Arachidonate 5-lipoxygenase	target
Resveratrol	Aryl hydrocarbon receptor	target
Resveratrol	Phosphatidylinositol 4-kinase type 2-beta	target
Resveratrol	Integrin alpha-5	target
Resveratrol	Integrin beta-3	target
Resveratrol	Serum albumin	carrier
Resveratrol	Amyloid beta A4 protein	target
Resveratrol	Alpha-synuclein	target
Resveratrol	Estrogen receptor alpha	target
Resveratrol	Melatonin receptor type 1A	target
Resveratrol	Melatonin receptor type 1B	target
Resveratrol	C-type lectin domain family 14 member A	target
Resveratrol	Nuclear receptor subfamily 1 group I member 2	target
Resveratrol	Nuclear receptor subfamily 1 group I member 3	target
Resveratrol	Solute carrier family 2, facilitated glucose transporter member 1	target
Resveratrol	Carbonyl reductase [NADPH] 1	target
Resveratrol	Peroxisome proliferator-activated receptor alpha	target
Resveratrol	Peroxisome proliferator-activated receptor gamma	target
Resveratrol	RAC-alpha serine/threonine-protein kinase	target
Resveratrol	Far upstream element-binding protein 2	target
Resveratrol	Tyrosine--tRNA ligase, cytoplasmic	target
Resveratrol	Cytochrome P450 2D6	enzyme
Resveratrol	Cytochrome P450 2B6	enzyme
Resveratrol	Cytochrome P450 2C19	enzyme
Resveratrol	Cytochrome P450 2C9	enzyme
Albendazole	Tubulin alpha-1A chain	target
Albendazole	Tubulin beta-4B chain	target
Albendazole	Cytochrome P450 3A4	enzyme
Albendazole	Fumarate reductase flavoprotein subunit	target
Albendazole	Cytochrome P450 1A1	enzyme
Albendazole	Cytochrome P450 1A2	enzyme
Albendazole	Tubulin beta-2 chain	target
Albendazole	Cytochrome P450 2C19	enzyme
Albendazole	P-glycoprotein 1	transporter
Bromazepam	Cytochrome P450 1A2	enzyme
Bromazepam	Cytochrome P450 2C19	enzyme
Bromazepam	Cytochrome P450 2E1	enzyme
Bromazepam	GABA(A) Receptor	target
Bromazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Desipramine	Muscarinic acetylcholine receptor M1	target
Desipramine	Sodium-dependent noradrenaline transporter	target
Desipramine	Beta-2 adrenergic receptor	target
Desipramine	Muscarinic acetylcholine receptor M2	target
Desipramine	Sodium-dependent serotonin transporter	target
Desipramine	Histamine H1 receptor	target
Desipramine	Beta-1 adrenergic receptor	target
Desipramine	Cytochrome P450 2D6	enzyme
Desipramine	Muscarinic acetylcholine receptor M3	target
Desipramine	Muscarinic acetylcholine receptor M4	target
Desipramine	Muscarinic acetylcholine receptor M5	target
Desipramine	Alpha-1 adrenergic receptors	target
Desipramine	5-hydroxytryptamine receptor 2A	target
Desipramine	Alpha-1-acid glycoprotein 1	carrier
Desipramine	Cytochrome P450 2B6	enzyme
Desipramine	Cytochrome P450 3A4	enzyme
Desipramine	Solute carrier family 22 member 2	transporter
Desipramine	Solute carrier family 22 member 1	transporter
Desipramine	Solute carrier family 22 member 3	transporter
Desipramine	Solute carrier family 22 member 5	transporter
Desipramine	P-glycoprotein 1	transporter
Desipramine	Solute carrier family 22 member 4	transporter
Desipramine	Cytochrome P450 1A2	enzyme
Desipramine	Cytochrome P450 2E1	enzyme
Desipramine	Sphingomyelin phosphodiesterase	target
Desipramine	5-hydroxytryptamine receptor 1A	target
Desipramine	5-hydroxytryptamine receptor 2C	target
Desipramine	Dopamine D2 receptor	target
Desipramine	Alpha-2 adrenergic receptors	target
Dexfenfluramine	Sodium-dependent serotonin transporter	target
Dexfenfluramine	5-hydroxytryptamine receptor 2C	target
Dexfenfluramine	Cytochrome P450 2D6	enzyme
Dexfenfluramine	Cytochrome P450 1A2	enzyme
Dexfenfluramine	Cytochrome P450 2E1	enzyme
Domperidone	Dopamine D2 receptor	target
Domperidone	Cytochrome P450 3A4	enzyme
Domperidone	Cytochrome P450 3A5	enzyme
Domperidone	Cytochrome P450 3A7	enzyme
Domperidone	P-glycoprotein 1	transporter
Domperidone	Cytochrome P450 1A2	enzyme
Domperidone	Cytochrome P450 2B6	enzyme
Domperidone	Cytochrome P450 2C8	enzyme
Domperidone	Cytochrome P450 2D6	enzyme
Domperidone	Dopamine D3 receptor	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-1	target
Ethanol	Glutamate receptor ionotropic, NMDA 3A	target
Ethanol	Glycine receptor subunit alpha-1	target
Ethanol	Glycine receptor subunit alpha-2	target
Ethanol	Cytochrome P450 2E1	enzyme
Ethanol	Cytochrome P450 1A1	enzyme
Ethanol	Cytochrome P450 1A2	enzyme
Ethanol	Cytochrome P450 2B6	enzyme
Ethanol	Cytochrome P450 2C19	enzyme
Ethanol	Cytochrome P450 2C9	enzyme
Ethanol	Cytochrome P450 3A4	enzyme
Ethanol	Cytochrome P450 4A11	enzyme
Ethanol	Alcohol dehydrogenase 1A	enzyme
Ethanol	Alcohol dehydrogenase 1B	enzyme
Ethanol	Alcohol dehydrogenase 1C	enzyme
Ethanol	Alcohol dehydrogenase class-3	enzyme
Ethanol	Voltage-dependent L-type calcium channel subunit beta-1	target
Ethanol	5-hydroxytryptamine receptor 3A	target
Ethanol	Alcohol dehydrogenase 4	enzyme
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-2	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-10	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-5	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-4	target
Ethanol	Alcohol dehydrogenase class 4 mu/sigma chain	enzyme
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-3	target
Ethanol	Glutamate receptor 1	target
Ethanol	Voltage-dependent calcium channel gamma-1 subunit	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-2	target
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-6	target
Ethanol	Glutamate receptor 2	target
Ethanol	Glutamate receptor 4	target
Ethanol	Glutamate receptor 3	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-4	target
Ethanol	Neuronal acetylcholine receptor subunit beta-2	target
Ethanol	G protein-activated inward rectifier potassium channel 1	target
Ethanol	G protein-activated inward rectifier potassium channel 2	target
Ethanol	Vascular cell adhesion protein 1	target
Ethanol	Equilibrative nucleoside transporter 1	target
Ethanol	G protein-activated inward rectifier potassium channel 4	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-7	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-9	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-1	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit beta-2	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Ethanol	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Ethanol	Alcohol dehydrogenase 6	enzyme
Ethanol	Neuronal acetylcholine receptor subunit beta-4	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-3	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-5	target
Ethanol	Neuronal acetylcholine receptor subunit alpha-6	target
Ethanol	Neuronal acetylcholine receptor subunit beta-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit gamma-1	target
Ethanol	Gamma-aminobutyric acid receptor subunit gamma-3	target
Ethanol	Gamma-aminobutyric acid receptor subunit epsilon	target
Ethanol	Gamma-aminobutyric acid receptor subunit pi	target
Ethanol	Gamma-aminobutyric acid receptor subunit theta	target
Ethanol	Gamma-aminobutyric acid receptor subunit delta	target
Ethanol	Alcohol dehydrogenase [NADP(+)]	enzyme
Ethanol	Equilibrative nucleoside transporter 2	target
Ethanol	5-hydroxytryptamine receptor 3E	target
Ethanol	5-hydroxytryptamine receptor 3B	target
Ethanol	5-hydroxytryptamine receptor 3D	target
Ethanol	5-hydroxytryptamine receptor 3C	target
Ethanol	Voltage-dependent calcium channel gamma-2 subunit	target
Ethanol	G protein-activated inward rectifier potassium channel 3	target
Ethanol	Neural cell adhesion molecule L1	target
Ethanol	Acetylcholinesterase	target
Ethanol	Alcohol dehydrogenase class 4 mu/sigma chain	target
Etoposide	DNA topoisomerase 2-alpha	target
Etoposide	Cytochrome P450 3A4	enzyme
Etoposide	Canalicular multispecific organic anion transporter 2	transporter
Etoposide	Multidrug resistance-associated protein 6	transporter
Etoposide	P-glycoprotein 1	transporter
Etoposide	Multidrug resistance-associated protein 1	transporter
Etoposide	Multidrug resistance-associated protein 7	transporter
Etoposide	Canalicular multispecific organic anion transporter 1	transporter
Etoposide	ATP-binding cassette sub-family G member 2	transporter
Etoposide	Cytochrome P450 1A2	enzyme
Etoposide	Cytochrome P450 2E1	enzyme
Etoposide	Cytochrome P450 3A5	enzyme
Etoposide	UDP-glucuronosyltransferase 1-1	enzyme
Etoposide	DNA topoisomerase 2-beta	target
Etoposide	Glutathione S-transferase theta-1	enzyme
Etoposide	Glutathione S-transferase P	enzyme
Etoposide	Prostaglandin G/H synthase 2	enzyme
Etoposide	Prostaglandin G/H synthase 1	enzyme
Lumiracoxib	Prostaglandin G/H synthase 2	target
Lumiracoxib	Prostaglandin G/H synthase 1	target
Lumiracoxib	Cytochrome P450 2C9	enzyme
Lumiracoxib	Cytochrome P450 2C19	enzyme
Lumiracoxib	UDP-glucuronosyltransferase 1-9	enzyme
Lumiracoxib	Cytochrome P450 1A2	enzyme
Malathion	Cholinesterase	target
Malathion	Cytochrome P450 1A2	enzyme
Malathion	Cytochrome P450 2B6	enzyme
Maprotiline	Histamine H1 receptor	target
Maprotiline	Sodium-dependent noradrenaline transporter	target
Maprotiline	Alpha-1 adrenergic receptors	target
Maprotiline	Cytochrome P450 2D6	enzyme
Maprotiline	Alpha-1-acid glycoprotein 1	carrier
Maprotiline	Muscarinic acetylcholine receptor M1	target
Maprotiline	Muscarinic acetylcholine receptor M2	target
Maprotiline	Muscarinic acetylcholine receptor M3	target
Maprotiline	Muscarinic acetylcholine receptor M4	target
Maprotiline	Muscarinic acetylcholine receptor M5	target
Maprotiline	Cytochrome P450 1A2	enzyme
Maprotiline	5-hydroxytryptamine receptor 2A	target
Maprotiline	5-hydroxytryptamine receptor 2C	target
Maprotiline	5-hydroxytryptamine receptor 7	target
Maprotiline	Dopamine D2 receptor	target
Maprotiline	Alpha-2 adrenergic receptors	target
Methadone	NMDA receptor	target
Methadone	Mu-type opioid receptor	target
Methadone	Cytochrome P450 2B6	enzyme
Methadone	Cytochrome P450 3A4	enzyme
Methadone	Cytochrome P450 2C19	enzyme
Methadone	Delta-type opioid receptor	target
Methadone	Cytochrome P450 3A7	enzyme
Methadone	Cytochrome P450 2D6	enzyme
Methadone	P-glycoprotein 1	transporter
Methadone	Cytochrome P450 2C8	enzyme
Methadone	Cytochrome P450 19A1	enzyme
Methadone	Cytochrome P450 1A2	enzyme
Methadone	Cytochrome P450 2C18	enzyme
Methadone	Cytochrome P450 2C9	enzyme
Methadone	5-hydroxytryptamine receptor 3A	target
Methadone	Alpha-1-acid glycoprotein 1	carrier
Methadone	Serum albumin	carrier
Methadone	Neuronal acetylcholine receptor subunit alpha-7	target
Methadone	Neuronal acetylcholine receptor subunit alpha-3	target
Methadone	Neuronal acetylcholine receptor subunit alpha-4	target
Methadone	Neuronal acetylcholine receptor subunit beta-2	target
Methadone	Cytochrome P450 3A Subfamily	enzyme
Methadone	UDP-glucuronosyltransferase 2B4	enzyme
Methoxyflurane	Calcium-transporting ATPase type 2C member 1	target
Methoxyflurane	NADH-ubiquinone oxidoreductase chain 1	target
Methoxyflurane	Gamma-aminobutyric acid receptor subunit alpha-1	target
Methoxyflurane	Potassium voltage-gated channel subfamily A member 1	target
Methoxyflurane	Glutamate receptor 1	target
Methoxyflurane	Glycine receptor subunit alpha-1	target
Methoxyflurane	Cytochrome P450 2E1	enzyme
Methoxyflurane	Cytochrome P450 1A2	enzyme
Methoxyflurane	Cytochrome P450 2A6	enzyme
Methoxyflurane	Cytochrome P450 2B6	enzyme
Methoxyflurane	Cytochrome P450 2C9	enzyme
Methoxyflurane	Cytochrome P450 2D6	enzyme
Methoxyflurane	Cytochrome P450 3A4	enzyme
Methoxyflurane	GABA(A) Receptor	target
Mianserin	Histamine H1 receptor	target
Mianserin	Alpha-2A adrenergic receptor	target
Mianserin	5-hydroxytryptamine receptor 2A	target
Mianserin	5-hydroxytryptamine receptor 2C	target
Mianserin	Cytochrome P450 2D6	enzyme
Mianserin	Sodium-dependent serotonin transporter	target
Mianserin	Cytochrome P450 3A4	enzyme
Mianserin	Cytochrome P450 1A2	enzyme
Mianserin	Cytochrome P450 2B6	enzyme
Mianserin	Sodium-dependent noradrenaline transporter	target
Mianserin	Histamine H4 receptor	target
Mianserin	5-hydroxytryptamine receptor 1A	target
Mianserin	Alpha-2C adrenergic receptor	target
Mianserin	5-hydroxytryptamine receptor 2B	target
Mianserin	5-hydroxytryptamine receptor 1F	target
Mianserin	Alpha-2B adrenergic receptor	target
Mianserin	Dopamine D3 receptor	target
Mianserin	Kappa-type opioid receptor	target
Mianserin	Sodium-dependent dopamine transporter	target
Mianserin	5-hydroxytryptamine receptor 7	target
Mianserin	Dopamine D2 receptor	target
Mianserin	5-hydroxytryptamine receptor 6	target
Mianserin	Alpha-1 adrenergic receptors	target
Mianserin	D(1) dopamine receptor	target
Pentoxifylline	5'-nucleotidase	target
Pentoxifylline	Adenosine receptor A1	target
Pentoxifylline	Adenosine receptor A2a	target
Pentoxifylline	Cytochrome P450 1A2	enzyme
Pentoxifylline	Phosphodiesterase enzymes	target
Perphenazine	Dopamine D1 receptor	target
Perphenazine	Dopamine D2 receptor	target
Perphenazine	Calmodulin	target
Perphenazine	Cytochrome P450 2D6	enzyme
Perphenazine	Cytochrome P450 1A2	enzyme
Perphenazine	Cytochrome P450 2C18	enzyme
Perphenazine	Cytochrome P450 2C19	enzyme
Perphenazine	Cytochrome P450 2C8	enzyme
Perphenazine	Cytochrome P450 2C9	enzyme
Perphenazine	Cytochrome P450 3A4	enzyme
Perphenazine	Serum albumin	carrier
Selegiline	Amine oxidase [flavin-containing] B	target
Selegiline	Cytochrome P450 2B6	enzyme
Selegiline	Amine oxidase [flavin-containing] A	target
Selegiline	Cytochrome P450 2A6	enzyme
Selegiline	Cytochrome P450 3A4	enzyme
Selegiline	P-glycoprotein 1	transporter
Selegiline	Cytochrome P450 1A2	enzyme
Selegiline	Cytochrome P450 2C19	enzyme
Selegiline	Cytochrome P450 2C8	enzyme
Selegiline	Cytochrome P450 2C9	enzyme
Selegiline	Cytochrome P450 2D6	enzyme
Theobromine	Cytochrome P450 1A2	enzyme
Theobromine	Cytochrome P450 2E1	enzyme
Theobromine	Adenosine receptor A1	target
Theobromine	Adenosine receptor A2a	target
Theobromine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Tolperisone	Cytochrome P450 1A2	enzyme
Ziprasidone	Alpha-1A adrenergic receptor	target
Ziprasidone	Dopamine D2 receptor	target
Ziprasidone	5-hydroxytryptamine receptor 2C	target
Ziprasidone	Dopamine D3 receptor	target
Ziprasidone	5-hydroxytryptamine receptor 1A	target
Ziprasidone	5-hydroxytryptamine receptor 1D	target
Ziprasidone	Histamine H1 receptor	target
Ziprasidone	5-hydroxytryptamine receptor 2A	target
Ziprasidone	Dopamine D4 receptor	target
Ziprasidone	5-hydroxytryptamine receptor 7	target
Ziprasidone	Cytochrome P450 3A4	enzyme
Ziprasidone	Alpha-2A adrenergic receptor	target
Ziprasidone	Alpha-1B adrenergic receptor	target
Ziprasidone	Alpha-2B adrenergic receptor	target
Ziprasidone	Alpha-2C adrenergic receptor	target
Ziprasidone	Dopamine D1 receptor	target
Ziprasidone	Dopamine D5 receptor	target
Ziprasidone	Muscarinic acetylcholine receptor M1	target
Ziprasidone	Muscarinic acetylcholine receptor M2	target
Ziprasidone	Muscarinic acetylcholine receptor M3	target
Ziprasidone	Muscarinic acetylcholine receptor M4	target
Ziprasidone	Muscarinic acetylcholine receptor M5	target
Ziprasidone	5-hydroxytryptamine receptor 1B	target
Ziprasidone	5-hydroxytryptamine receptor 1E	target
Ziprasidone	5-hydroxytryptamine receptor 6	target
Ziprasidone	Aldehyde oxidase	enzyme
Ziprasidone	Serum albumin	carrier
Ziprasidone	P-glycoprotein 1	transporter
Ziprasidone	Alpha-1-acid glycoprotein 1	carrier
Ziprasidone	5-hydroxytryptamine 3 receptor	target
Ziprasidone	5-hydroxytryptamine receptor 5A	target
Erlotinib	Epidermal growth factor receptor	target
Erlotinib	Cytochrome P450 3A4	enzyme
Erlotinib	ATP-binding cassette sub-family G member 2	transporter
Erlotinib	P-glycoprotein 1	transporter
Erlotinib	Nuclear receptor subfamily 1 group I member 2	target
Erlotinib	Cytochrome P450 3A5	enzyme
Erlotinib	Cytochrome P450 1A1	enzyme
Erlotinib	Cytochrome P450 1A2	enzyme
Erlotinib	Cytochrome P450 1B1	enzyme
Erlotinib	Cytochrome P450 2D6	enzyme
Erlotinib	Cytochrome P450 2C8	enzyme
Erlotinib	UDP-glucuronosyltransferase 1-1	enzyme
Erlotinib	Serum albumin	carrier
Erlotinib	Alpha-1-acid glycoprotein 1	carrier
Erlotinib	Solute carrier organic anion transporter family member 2B1	transporter
Erlotinib	Epidermal growth factor receptor	enzyme
Cilostazol	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Cilostazol	Cytochrome P450 2C19	enzyme
Cilostazol	Cytochrome P450 3A4	enzyme
Cilostazol	Cytochrome P450 3A5	enzyme
Cilostazol	Cytochrome P450 3A7	enzyme
Cilostazol	Cytochrome P450 1A2	enzyme
Cilostazol	Cytochrome P450 2D6	enzyme
Eltrombopag	Thrombopoietin receptor	target
Eltrombopag	Cytochrome P450 2C8	enzyme
Eltrombopag	Cytochrome P450 1A2	enzyme
Eltrombopag	UDP-glucuronosyltransferase 1-1	enzyme
Eltrombopag	UDP-glucuronosyltransferase 1-3	enzyme
Eltrombopag	Solute carrier organic anion transporter family member 1B1	transporter
Eltrombopag	ATP-binding cassette sub-family G member 2	transporter
Eltrombopag	UDP-glucuronosyltransferase 1-9	enzyme
Clonidine	Alpha-2A adrenergic receptor	target
Clonidine	Cytochrome P450 2D6	enzyme
Clonidine	Alpha-2B adrenergic receptor	target
Clonidine	Alpha-2C adrenergic receptor	target
Clonidine	Solute carrier family 22 member 3	transporter
Clonidine	Solute carrier family 22 member 5	transporter
Clonidine	Solute carrier family 22 member 4	transporter
Clonidine	Cytochrome P450 1A2	enzyme
Clonidine	Cytochrome P450 3A4	enzyme
Clonidine	Cytochrome P450 1A1	enzyme
Clonidine	Cytochrome P450 3A5	enzyme
Clonidine	Alpha-1A adrenergic receptor	target
Clonidine	Alpha-1B adrenergic receptor	target
Clonidine	Alpha-1D adrenergic receptor	target
Clonidine	Serum albumin	carrier
Muraglitazar	Peroxisome proliferator-activated receptor alpha	target
Muraglitazar	Peroxisome proliferator-activated receptor gamma	target
Muraglitazar	Cytochrome P450 1A2	enzyme
Muraglitazar	UDP-glucuronosyltransferase 1-3	enzyme
Muraglitazar	UDP-glucuronosyltransferase 1-1	enzyme
Muraglitazar	Cytochrome P450 2C8	enzyme
Vadimezan	UDP-glucuronosyltransferase 1-9	enzyme
Vadimezan	UDP-glucuronosyltransferase 2B7	enzyme
Vadimezan	Cytochrome P450 1A2	enzyme
Nabumetone	Prostaglandin G/H synthase 1	target
Nabumetone	Prostaglandin G/H synthase 2	target
Nabumetone	Myeloperoxidase	enzyme
Nabumetone	Cytochrome P450 1A2	enzyme
Nabumetone	Cytochrome P450 2C9	enzyme
Nabumetone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Nabumetone	Aldo-keto reductase family 1 member C1	enzyme
Nabumetone	Aldo-keto reductase family 1 member C2	enzyme
Nabumetone	Aldo-keto reductase family 1 member C4	enzyme
Nabumetone	Serum albumin	carrier
Pazopanib	Vascular endothelial growth factor receptor 1	target
Pazopanib	Vascular endothelial growth factor receptor 2	target
Pazopanib	Vascular endothelial growth factor receptor 3	target
Pazopanib	Platelet-derived growth factor receptor alpha	target
Pazopanib	Platelet-derived growth factor receptor beta	target
Pazopanib	Mast/stem cell growth factor receptor Kit	target
Pazopanib	Cytochrome P450 3A4	enzyme
Pazopanib	Cytochrome P450 2D6	enzyme
Pazopanib	Cytochrome P450 2C8	enzyme
Pazopanib	Cytochrome P450 1A2	enzyme
Pazopanib	P-glycoprotein 1	transporter
Pazopanib	ATP-binding cassette sub-family G member 2	transporter
Pazopanib	Solute carrier organic anion transporter family member 1B1	transporter
Pazopanib	UDP-glucuronosyltransferase 1-1	transporter
Pazopanib	Fibroblast growth factor receptor 3	target
Pazopanib	Tyrosine-protein kinase ITK/TSK	target
Pazopanib	Fibroblast growth factor 1	target
Pazopanib	SH2B adapter protein 3	target
Ulipristal	Progesterone receptor	target
Ulipristal	Glucocorticoid receptor	target
Ulipristal	Androgen receptor	target
Ulipristal	Cytochrome P450 3A4	enzyme
Ulipristal	Cytochrome P450 1A2	enzyme
Ulipristal	Serum albumin	carrier
Ulipristal	Alpha-1-acid glycoprotein 1	carrier
Lorcaserin	5-hydroxytryptamine receptor 2C	target
Lorcaserin	Cytochrome P450 1A2	enzyme
Lorcaserin	Cytochrome P450 2A6	enzyme
Lorcaserin	Cytochrome P450 2B6	enzyme
Lorcaserin	Cytochrome P450 2C19	enzyme
Lorcaserin	Cytochrome P450 2D6	enzyme
Lorcaserin	Cytochrome P450 3A4	enzyme
Lorcaserin	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Lorcaserin	Cytochrome P450 1A1	enzyme
Apixaban	Coagulation factor X	target
Apixaban	Cytochrome P450 3A4	enzyme
Apixaban	Cytochrome P450 1A2	enzyme
Apixaban	Cytochrome P450 2C8	enzyme
Apixaban	Cytochrome P450 2C9	enzyme
Apixaban	Cytochrome P450 2C19	enzyme
Apixaban	Cytochrome P450 2J2	enzyme
Apixaban	P-glycoprotein 1	transporter
Apixaban	ATP-binding cassette sub-family G member 2	transporter
Apixaban	Cytochrome P450 3A5	enzyme
Axitinib	Vascular endothelial growth factor receptor 1	target
Axitinib	Vascular endothelial growth factor receptor 2	target
Axitinib	Vascular endothelial growth factor receptor 3	target
Axitinib	Cytochrome P450 3A4	enzyme
Axitinib	Cytochrome P450 3A5	enzyme
Axitinib	Cytochrome P450 1A2	enzyme
Axitinib	Cytochrome P450 2C19	enzyme
Axitinib	UDP-glucuronosyltransferase 1-1	enzyme
Axitinib	P-glycoprotein 1	transporter
Axitinib	Solute carrier organic anion transporter family member 1B1	transporter
Pomalidomide	Cytochrome P450 1A2	enzyme
Pomalidomide	Cytochrome P450 3A4	enzyme
Pomalidomide	P-glycoprotein 1	transporter
Pomalidomide	Protein cereblon	target
Pomalidomide	Tumor necrosis factor	target
Pomalidomide	Prostaglandin G/H synthase 2	target
Ixazomib	Cytochrome P450 3A4	enzyme
Ixazomib	Cytochrome P450 1A2	enzyme
Ixazomib	Cytochrome P450 2B6	enzyme
Ixazomib	Cytochrome P450 2C8	enzyme
Ixazomib	Cytochrome P450 2D6	enzyme
Ixazomib	Cytochrome P450 2C19	enzyme
Ixazomib	Cytochrome P450 2C9	enzyme
Bendamustine	Cytochrome P450 1A2	enzyme
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Poly [ADP-ribose] polymerase 3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	P-glycoprotein 1	transporter
Rucaparib	ATP-binding cassette sub-family G member 2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	Multidrug resistance-associated protein 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Solute carrier family 22 member 8	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1-1	enzyme
Icotinib	Epidermal growth factor receptor	target
Icotinib	Cytochrome P450 3A4	enzyme
Icotinib	Cytochrome P450 1A2	enzyme
Icotinib	Cytochrome P450 3A5	enzyme
Deutetrabenazine	Synaptic vesicular amine transporter	target
Deutetrabenazine	Carbonyl reductase [NADPH] 1	enzyme
Deutetrabenazine	Carbonyl reductase [NADPH] 3	enzyme
Deutetrabenazine	Cytochrome P450 2D6	enzyme
Deutetrabenazine	Cytochrome P450 1A2	enzyme
Deutetrabenazine	Cytochrome P450 3A5	enzyme
Deutetrabenazine	Cytochrome P450 3A4	enzyme
Stiripentol	Cytochrome P450 2C19	enzyme
Stiripentol	Cytochrome P450 2D6	enzyme
Stiripentol	Cytochrome P450 3A4	enzyme
Stiripentol	Cytochrome P450 1A2	enzyme
Stiripentol	Cytochrome P450 2C9	enzyme
Stiripentol	GABA(A) Receptor	target
Stiripentol	L-lactate dehydrogenase A chain	target
Stiripentol	L-lactate dehydrogenase B chain	target
Stiripentol	Cytochrome P450 2B6	enzyme
Stiripentol	Cytochrome P450 2C8	enzyme
Stiripentol	P-glycoprotein 1	transporter
Stiripentol	ATP-binding cassette sub-family G member 2	transporter
Voxilaprevir	Cytochrome P450 3A4	enzyme
Voxilaprevir	Cytochrome P450 1A2	enzyme
Voxilaprevir	Cytochrome P450 2C8	enzyme
Voxilaprevir	NS3/4A protein	target
Voxilaprevir	P-glycoprotein 1	transporter
Voxilaprevir	ATP-binding cassette sub-family G member 2	transporter
Voxilaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Voxilaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Cytochrome P450 1A2	enzyme
Enasidenib	Cytochrome P450 2B6	enzyme
Enasidenib	Isocitrate dehydrogenase [NADP], mitochondrial	target
Enasidenib	Cytochrome P450 2C8	enzyme
Enasidenib	Cytochrome P450 2C9	enzyme
Enasidenib	Cytochrome P450 2C19	enzyme
Enasidenib	Cytochrome P450 2D6	enzyme
Enasidenib	Cytochrome P450 3A4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-1	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-3	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-4	enzyme
Enasidenib	UDP-glucuronosyltransferase 1-9	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B7	enzyme
Enasidenib	UDP-glucuronosyltransferase 2B15	enzyme
Enasidenib	P-glycoprotein 1	transporter
Enasidenib	ATP-binding cassette sub-family G member 2	transporter
Enasidenib	Solute carrier family 22 member 6	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Enasidenib	Solute carrier family 22 member 2	transporter
Enasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Enasidenib	Solute carrier family 22 member 8	transporter
Estradiol acetate	Estrogen receptor alpha	target
Estradiol acetate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol acetate	Sex hormone-binding globulin	carrier
Estradiol acetate	Estrogen receptor beta	target
Estradiol acetate	Cytochrome P450 1A2	enzyme
Estradiol acetate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol acetate	Serum albumin	carrier
Estradiol acetate	Fatty acid-binding protein, intestinal	carrier
Estradiol acetate	Cytochrome P450 3A4	enzyme
Estradiol acetate	Cytochrome P450 3A5	enzyme
Estradiol acetate	Cytochrome P450 3A7	enzyme
Estradiol acetate	Solute carrier family 22 member 2	transporter
Estradiol acetate	Solute carrier family 22 member 1	transporter
Estradiol acetate	Solute carrier family 22 member 3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol acetate	Multidrug resistance-associated protein 7	transporter
Estradiol acetate	Solute carrier family 22 member 11	transporter
Estradiol acetate	ATP-binding cassette sub-family G member 2	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol acetate	P-glycoprotein 1	transporter
Estradiol acetate	Cytochrome P450 1A1	enzyme
Estradiol acetate	Cytochrome P450 1B1	enzyme
Estradiol acetate	Cytochrome P450 2C19	enzyme
Estradiol acetate	Cytochrome P450 2C8	enzyme
Estradiol acetate	Cytochrome P450 2C9	enzyme
Estradiol acetate	Solute carrier family 22 member 8	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol acetate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol acetate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol acetate	Nuclear receptor coactivator 2	target
Estradiol acetate	G-protein coupled estrogen receptor 1	target
Estradiol acetate	ATP synthase subunit a	target
Estradiol acetate	Beclin-1	target
Estradiol acetate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol acetate	Estrogen-related receptor gamma	target
Estradiol benzoate	Estrogen receptor alpha	target
Estradiol benzoate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol benzoate	Sex hormone-binding globulin	carrier
Estradiol benzoate	Estrogen receptor beta	target
Estradiol benzoate	Cytochrome P450 1A2	enzyme
Estradiol benzoate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol benzoate	Serum albumin	carrier
Estradiol benzoate	Fatty acid-binding protein, intestinal	carrier
Estradiol benzoate	Cytochrome P450 3A4	enzyme
Estradiol benzoate	Cytochrome P450 3A5	enzyme
Estradiol benzoate	Cytochrome P450 3A7	enzyme
Estradiol benzoate	Solute carrier family 22 member 2	transporter
Estradiol benzoate	Solute carrier family 22 member 1	transporter
Estradiol benzoate	Solute carrier family 22 member 3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol benzoate	Multidrug resistance-associated protein 7	transporter
Estradiol benzoate	Solute carrier family 22 member 11	transporter
Estradiol benzoate	ATP-binding cassette sub-family G member 2	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol benzoate	P-glycoprotein 1	transporter
Estradiol benzoate	Cytochrome P450 1A1	enzyme
Estradiol benzoate	Cytochrome P450 1B1	enzyme
Estradiol benzoate	Cytochrome P450 2C19	enzyme
Estradiol benzoate	Cytochrome P450 2C8	enzyme
Estradiol benzoate	Cytochrome P450 2C9	enzyme
Estradiol benzoate	Solute carrier family 22 member 8	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol benzoate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol benzoate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol benzoate	Nuclear receptor coactivator 2	target
Estradiol benzoate	G-protein coupled estrogen receptor 1	target
Estradiol benzoate	ATP synthase subunit a	target
Estradiol benzoate	Beclin-1	target
Estradiol benzoate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol benzoate	Estrogen-related receptor gamma	target
Estradiol cypionate	Estrogen receptor alpha	target
Estradiol cypionate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol cypionate	Sex hormone-binding globulin	carrier
Estradiol cypionate	Estrogen receptor beta	target
Estradiol cypionate	Cytochrome P450 1A2	enzyme
Estradiol cypionate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol cypionate	Serum albumin	carrier
Estradiol cypionate	Fatty acid-binding protein, intestinal	carrier
Estradiol cypionate	Cytochrome P450 3A4	enzyme
Estradiol cypionate	Cytochrome P450 3A5	enzyme
Estradiol cypionate	Cytochrome P450 3A7	enzyme
Estradiol cypionate	Solute carrier family 22 member 2	transporter
Estradiol cypionate	Solute carrier family 22 member 1	transporter
Estradiol cypionate	Solute carrier family 22 member 3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol cypionate	Multidrug resistance-associated protein 7	transporter
Estradiol cypionate	Solute carrier family 22 member 11	transporter
Estradiol cypionate	ATP-binding cassette sub-family G member 2	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol cypionate	P-glycoprotein 1	transporter
Estradiol cypionate	Cytochrome P450 1A1	enzyme
Estradiol cypionate	Cytochrome P450 1B1	enzyme
Estradiol cypionate	Cytochrome P450 2C19	enzyme
Estradiol cypionate	Cytochrome P450 2C8	enzyme
Estradiol cypionate	Cytochrome P450 2C9	enzyme
Estradiol cypionate	Solute carrier family 22 member 8	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol cypionate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol cypionate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol cypionate	Nuclear receptor coactivator 2	target
Estradiol cypionate	G-protein coupled estrogen receptor 1	target
Estradiol cypionate	ATP synthase subunit a	target
Estradiol cypionate	Beclin-1	target
Estradiol cypionate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol cypionate	Estrogen-related receptor gamma	target
Estradiol dienanthate	Estrogen receptor alpha	target
Estradiol dienanthate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol dienanthate	Sex hormone-binding globulin	carrier
Estradiol dienanthate	Estrogen receptor beta	target
Estradiol dienanthate	Cytochrome P450 1A2	enzyme
Estradiol dienanthate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol dienanthate	Serum albumin	carrier
Estradiol dienanthate	Fatty acid-binding protein, intestinal	carrier
Estradiol dienanthate	Cytochrome P450 3A4	enzyme
Estradiol dienanthate	Cytochrome P450 3A5	enzyme
Estradiol dienanthate	Cytochrome P450 3A7	enzyme
Estradiol dienanthate	Solute carrier family 22 member 2	transporter
Estradiol dienanthate	Solute carrier family 22 member 1	transporter
Estradiol dienanthate	Solute carrier family 22 member 3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol dienanthate	Multidrug resistance-associated protein 7	transporter
Estradiol dienanthate	Solute carrier family 22 member 11	transporter
Estradiol dienanthate	ATP-binding cassette sub-family G member 2	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol dienanthate	P-glycoprotein 1	transporter
Estradiol dienanthate	Cytochrome P450 1A1	enzyme
Estradiol dienanthate	Cytochrome P450 1B1	enzyme
Estradiol dienanthate	Cytochrome P450 2C19	enzyme
Estradiol dienanthate	Cytochrome P450 2C8	enzyme
Estradiol dienanthate	Cytochrome P450 2C9	enzyme
Estradiol dienanthate	Solute carrier family 22 member 8	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol dienanthate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol dienanthate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol dienanthate	Nuclear receptor coactivator 2	target
Estradiol dienanthate	G-protein coupled estrogen receptor 1	target
Estradiol dienanthate	ATP synthase subunit a	target
Estradiol dienanthate	Beclin-1	target
Estradiol dienanthate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol dienanthate	Estrogen-related receptor gamma	target
Estradiol valerate	Estrogen receptor alpha	target
Estradiol valerate	Nuclear receptor subfamily 1 group I member 2	target
Estradiol valerate	Sex hormone-binding globulin	carrier
Estradiol valerate	Estrogen receptor beta	target
Estradiol valerate	Cytochrome P450 1A2	enzyme
Estradiol valerate	UDP-glucuronosyltransferase 1-1	enzyme
Estradiol valerate	Serum albumin	carrier
Estradiol valerate	Fatty acid-binding protein, intestinal	carrier
Estradiol valerate	Cytochrome P450 3A4	enzyme
Estradiol valerate	Cytochrome P450 3A5	enzyme
Estradiol valerate	Cytochrome P450 3A7	enzyme
Estradiol valerate	Solute carrier family 22 member 2	transporter
Estradiol valerate	Solute carrier family 22 member 1	transporter
Estradiol valerate	Solute carrier family 22 member 3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 2B1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1A2	transporter
Estradiol valerate	Multidrug resistance-associated protein 7	transporter
Estradiol valerate	Solute carrier family 22 member 11	transporter
Estradiol valerate	ATP-binding cassette sub-family G member 2	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B1	transporter
Estradiol valerate	P-glycoprotein 1	transporter
Estradiol valerate	Cytochrome P450 1A1	enzyme
Estradiol valerate	Cytochrome P450 1B1	enzyme
Estradiol valerate	Cytochrome P450 2C19	enzyme
Estradiol valerate	Cytochrome P450 2C8	enzyme
Estradiol valerate	Cytochrome P450 2C9	enzyme
Estradiol valerate	Solute carrier family 22 member 8	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1B3	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 1C1	transporter
Estradiol valerate	Solute carrier organic anion transporter family member 4A1	transporter
Estradiol valerate	Neuronal acetylcholine receptor subunit alpha-4	target
Estradiol valerate	Nuclear receptor coactivator 2	target
Estradiol valerate	G-protein coupled estrogen receptor 1	target
Estradiol valerate	ATP synthase subunit a	target
Estradiol valerate	Beclin-1	target
Estradiol valerate	Estradiol 17-beta-dehydrogenase 2	target
Estradiol valerate	Estrogen-related receptor gamma	target
Zotepine	D(1) dopamine receptor	target
Zotepine	Dopamine D2 receptor	target
Zotepine	5-hydroxytryptamine receptor 2A	target
Zotepine	5-hydroxytryptamine receptor 6	target
Zotepine	5-hydroxytryptamine receptor 7	target
Zotepine	Sodium-dependent noradrenaline transporter	target
Zotepine	Sodium-dependent serotonin transporter	target
Zotepine	Cytochrome P450 1A2	enzyme
Zotepine	Cytochrome P450 3A4	enzyme
Lofexidine	Alpha-2A adrenergic receptor	target
Lofexidine	Alpha-1A adrenergic receptor	target
Lofexidine	5-hydroxytryptamine receptor 1A	target
Lofexidine	5-hydroxytryptamine receptor 7	target
Lofexidine	5-hydroxytryptamine receptor 2C	target
Lofexidine	5-hydroxytryptamine receptor 1D	target
Lofexidine	Cytochrome P450 2D6	enzyme
Lofexidine	Cytochrome P450 1A2	enzyme
Lofexidine	Cytochrome P450 2C19	enzyme
Lofexidine	ATP-binding cassette sub-family B member 5	transporter
Lofexidine	Multidrug and toxin extrusion protein 1	transporter
Tasimelteon	Melatonin receptor type 1A	target
Tasimelteon	Melatonin receptor type 1B	target
Tasimelteon	Cytochrome P450 3A4	enzyme
Tasimelteon	Cytochrome P450 1A2	enzyme
Pirfenidone	Cytochrome P450 1A2	enzyme
Pirfenidone	Cytochrome P450 2C9	enzyme
Pirfenidone	Cytochrome P450 2C19	enzyme
Pirfenidone	Cytochrome P450 2D6	enzyme
Pirfenidone	Cytochrome P450 2E1	enzyme
Pirfenidone	Serum albumin	carrier
Pirfenidone	Cytochrome P450 3A4	enzyme
Pirfenidone	P-glycoprotein 1	transporter
Ramosetron	5-hydroxytryptamine receptor 3A	target
Ramosetron	Cytochrome P450 1A2	enzyme
Acetaminophen	Prostaglandin G/H synthase 1	target
Acetaminophen	Prostaglandin G/H synthase 2	target
Acetaminophen	Cytochrome P450 1A2	enzyme
Acetaminophen	Cytochrome P450 2E1	enzyme
Acetaminophen	P-glycoprotein 1	transporter
Acetaminophen	Cytochrome P450 2D6	enzyme
Acetaminophen	Cytochrome P450 2A6	enzyme
Acetaminophen	Cytochrome P450 3A4	enzyme
Acetaminophen	UDP-glucuronosyltransferase 1-1	enzyme
Acetaminophen	UDP-glucuronosyltransferase 1-6	enzyme
Acetaminophen	UDP-glucuronosyltransferase 1-9	enzyme
Acetaminophen	UDP-glucuronosyltransferase 2B15	enzyme
Acetaminophen	Sulfotransferase 1A1	enzyme
Acetaminophen	Sulfotransferase 1A3/1A4	enzyme
Acetaminophen	Arylamine N-acetyltransferase 2	enzyme
Acetaminophen	Prostaglandin E synthase 3	target
Acetaminophen	Transient receptor potential cation channel subfamily V member 1	target
Acetaminophen	Serum albumin	carrier
Acetaminophen	Fatty-acid amide hydrolase 1	enzyme
Acetaminophen	Glutathione S-transferase P	enzyme
Acetaminophen	Glutathione S-transferase Mu 1	enzyme
Clopidogrel	P2Y purinoceptor 12	target
Clopidogrel	Cytochrome P450 3A4	enzyme
Clopidogrel	Cytochrome P450 2B6	enzyme
Clopidogrel	Cytochrome P450 3A5	enzyme
Clopidogrel	Cytochrome P450 2C19	enzyme
Clopidogrel	Cytochrome P450 2C9	enzyme
Clopidogrel	Cytochrome P450 1A2	enzyme
Clopidogrel	Cytochrome P450 2C8	enzyme
Clopidogrel	Liver carboxylesterase 1	enzyme
Clopidogrel	P-glycoprotein 1	transporter
Clopidogrel	Solute carrier family 22 member 1	transporter
Clopidogrel	Solute carrier family 22 member 2	transporter
Clopidogrel	Serum albumin	carrier
Fluvoxamine	Sodium-dependent serotonin transporter	target
Fluvoxamine	Cytochrome P450 1A2	enzyme
Fluvoxamine	Cytochrome P450 2D6	enzyme
Fluvoxamine	Cytochrome P450 2C9	enzyme
Fluvoxamine	Cytochrome P450 2C19	enzyme
Fluvoxamine	Cytochrome P450 1A1	enzyme
Fluvoxamine	Cytochrome P450 3A4	enzyme
Fluvoxamine	Cytochrome P450 3A Subfamily	enzyme
Fluvoxamine	P-glycoprotein 1	transporter
Fluvoxamine	Cytochrome P450 2B6	enzyme
Fluvoxamine	Potassium voltage-gated channel subfamily H member 2	target
Fluvoxamine	Bile salt export pump	transporter
Tegafur	Cytochrome P450 2A6	enzyme
Tegafur	Thymidylate synthase	target
Tegafur	Cytochrome P450 1A2	enzyme
Tegafur	Cytochrome P450 2C8	enzyme
Tegafur	Cytochrome P450 2E1	enzyme
Tegafur	Cytochrome P450 3A5	enzyme
Tegafur	Thyroxine-binding globulin	carrier
Amiodarone	Beta adrenergic receptor	target
Amiodarone	HERG human cardiac K+ channel	target
Amiodarone	Cytochrome P450 2C8	enzyme
Amiodarone	Cytochrome P450 2C9	enzyme
Amiodarone	Cytochrome P450 2D6	enzyme
Amiodarone	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Amiodarone	Voltage gated L-type calcium channel	target
Amiodarone	Cytochrome P450 3A4	enzyme
Amiodarone	Cytochrome P450 1A2	enzyme
Amiodarone	Cytochrome P450 1A1	enzyme
Amiodarone	P-glycoprotein 1	transporter
Amiodarone	Cytochrome P450 2C19	enzyme
Amiodarone	Cytochrome P450 2A6	enzyme
Amiodarone	Thyroid hormone receptor	target
Amiodarone	Peroxisome proliferator-activated receptor gamma	target
Amiodarone	Bile salt export pump	transporter
Amiodarone	Solute carrier family 22 member 2	transporter
Amiodarone	Cytochrome P450 2J2	enzyme
Amiodarone	Peroxisome proliferator-activated receptor alpha	target
Amiodarone	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	target
Amiodarone	Serum albumin	carrier
Dihydralazine	Cytochrome P450 1A2	enzyme
Pimobendan	Cytochrome P450 1A2	enzyme
Ranitidine	Histamine H2 receptor	target
Ranitidine	Cytochrome P450 1A2	enzyme
Ranitidine	Cytochrome P450 2D6	enzyme
Ranitidine	Solute carrier family 22 member 1	transporter
Ranitidine	P-glycoprotein 1	transporter
Ranitidine	Solute carrier family 22 member 8	transporter
Ranitidine	Cytochrome P450 3A4	enzyme
Ranitidine	Acetylcholinesterase	target
Ranitidine	Solute carrier family 22 member 2	transporter
Ranitidine	Acetylcholinesterase	enzyme
Perampanel	Glutamate receptor 1	target
Perampanel	Cytochrome P450 3A4	enzyme
Perampanel	Cytochrome P450 3A5	enzyme
Perampanel	Cytochrome P450 1A2	enzyme
Perampanel	Cytochrome P450 2B6	enzyme
(R)-warfarin	Serum albumin	carrier
(R)-warfarin	Cytochrome P450 2C8	enzyme
(R)-warfarin	Cytochrome P450 2C9	enzyme
(R)-warfarin	Cytochrome P450 2C18	enzyme
(R)-warfarin	Cytochrome P450 2C19	enzyme
(R)-warfarin	Cytochrome P450 1A2	enzyme
(R)-warfarin	Cytochrome P450 1A1	enzyme
(R)-warfarin	Cytochrome P450 3A4	enzyme
6-O-benzylguanine	Cytochrome P450 3A4	enzyme
8-chlorotheophylline	Adenosine receptor A2a	target
8-chlorotheophylline	Cytochrome P450 1A2	enzyme
Hypoxanthine	Purine nucleoside phosphorylase	target
Hypoxanthine	Cytochrome P450 1A2	enzyme
Lisofylline	Cytochrome P450 1A2	enzyme
Oxtriphylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Oxtriphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Oxtriphylline	Adenosine receptor A2a	target
Oxtriphylline	Adenosine receptor A1	target
Oxtriphylline	Cytochrome P450 1A2	enzyme
Oxtriphylline	Solute carrier family 22 member 7	transporter
Oxtriphylline	Histone deacetylase 2	target
Xanthine	Purine nucleoside phosphorylase 2	target
Xanthine	Xanthine phosphoribosyltransferase	target
Xanthine	Cytochrome P450 1A2	enzyme
Temafloxacin	DNA gyrase subunit A	target
Temafloxacin	DNA topoisomerase 4 subunit A	target
Temafloxacin	Cytochrome P450 1A2	enzyme
Acefylline	Cytochrome P450 1A2	enzyme
Acyclovir	DNA polymerase catalytic subunit	target
Acyclovir	DNA polymerase catalytic subunit	target
Acyclovir	Solute carrier family 22 member 1	transporter
Acyclovir	Solute carrier family 22 member 6	transporter
Acyclovir	Solute carrier family 22 member 8	transporter
Acyclovir	Ileal sodium/bile acid cotransporter	transporter
Acyclovir	Multidrug and toxin extrusion protein 1	transporter
Acyclovir	Multidrug and toxin extrusion protein 2	transporter
Acyclovir	Thymidine kinase	enzyme
Acyclovir	Guanylate kinase	enzyme
Acyclovir	Nucleoside diphosphokinase	enzyme
Acyclovir	Pyruvate Kinases	enzyme
Acyclovir	Creatine Kinases	enzyme
Acyclovir	Phosphoglycerate Kinases	enzyme
Acyclovir	Succinyl-CoA Synthetases	enzyme
Acyclovir	Phosphoenolpyruvate Carboxykinases	enzyme
Acyclovir	Adenylosuccinate Synthetases	enzyme
Acyclovir	Serum albumin	carrier
Bamifylline	Cytochrome P450 1A2	enzyme
Bromotheophylline	Cytochrome P450 1A2	enzyme
Bufylline	Cytochrome P450 1A2	enzyme
Doxofylline	Adenosine receptor A2a	target
Doxofylline	Beta-2 adrenergic receptor	target
Doxofylline	Cytochrome P450 1A2	enzyme
Doxofylline	cGMP-dependent 3',5'-cyclic phosphodiesterase	target
Entecavir	DNA	target
Etamiphylline	Cytochrome P450 1A2	enzyme
Fenethylline	Cytochrome P450 1A2	enzyme
Peldesine	Purine nucleoside phosphorylase	target
Pemetrexed	Thymidylate synthase	target
Pemetrexed	Dihydrofolate reductase	target
Pemetrexed	Trifunctional purine biosynthetic protein adenosine-3	target
Pemetrexed	Deoxycytidine kinase	enzyme
Pemetrexed	Bifunctional purine biosynthesis protein PURH	target
Pemetrexed	Equilibrative nucleoside transporter 1	enzyme
Pemetrexed	Solute carrier family 22 member 8	transporter
Pemetrexed	Folate transporter 1	transporter
Pemetrexed	Proton-coupled folate transporter	transporter
Pemetrexed	ATP-binding cassette sub-family G member 2	transporter
Pemetrexed	Multidrug resistance-associated protein 5	transporter
Pemetrexed	Solute carrier family 22 member 6	transporter
Pemetrexed	Serum albumin	carrier
Pemetrexed	Solute carrier family 22 member 11	transporter
Penciclovir	DNA polymerase catalytic subunit	target
Penciclovir	Thymidine kinase	target
Pentifylline	Cytochrome P450 1A2	enzyme
Propentofylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Propentofylline	Cytochrome P450 1A2	enzyme
Proxyphylline	Cytochrome P450 1A2	enzyme
Propacetamol	Cholinesterase	enzyme
Propacetamol	Prostaglandin G/H synthase 1	target
Propacetamol	Prostaglandin G/H synthase 2	target
Propacetamol	Transient receptor potential cation channel subfamily V member 1	target
Propacetamol	Cannabinoid receptor 1	target
Propacetamol	Cytochrome P450 2E1	enzyme
Propacetamol	Cytochrome P450 1A2	enzyme
Propacetamol	Cytochrome P450 2D6	enzyme
Propacetamol	UDP-glucuronosyltransferase 1-1	enzyme
Propacetamol	UDP-glucuronosyltransferase 1-6	enzyme
Propacetamol	UDP-glucuronosyltransferase 1-9	enzyme
Propacetamol	UDP-glucuronosyltransferase 2B15	enzyme
Propacetamol	UDP-glucuronosyltransferase 1-10	enzyme
Propacetamol	Sulfotransferase 1A1	enzyme
Propacetamol	Sulfotransferase 1A3/1A4	enzyme
Propacetamol	Estrogen sulfotransferase	enzyme
Propacetamol	Bile salt sulfotransferase	enzyme
Propacetamol	Arylamine N-acetyltransferase 2	enzyme
Propacetamol	Cytochrome P450 2C9	enzyme
Propacetamol	Cytochrome P450 3A4	enzyme
Nicotine	Neuronal acetylcholine receptor subunit alpha-2	target
Nicotine	Neuronal acetylcholine receptor subunit beta-2	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-7	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-4	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-10	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-9	target
Nicotine	Cytochrome P450 2A6	enzyme
Nicotine	Cytochrome P450 2E1	enzyme
Nicotine	Cytochrome P450 2A13	enzyme
Nicotine	Cytochrome P450 2B6	enzyme
Nicotine	Neuronal acetylcholine receptor subunit beta-4	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-3	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-5	target
Nicotine	Neuronal acetylcholine receptor subunit alpha-6	target
Nicotine	Neuronal acetylcholine receptor subunit beta-3	target
Nicotine	Solute carrier family 22 member 2	transporter
Nicotine	Solute carrier family 22 member 1	transporter
Nicotine	Solute carrier family 22 member 3	transporter
Nicotine	Solute carrier family 22 member 5	transporter
Nicotine	Solute carrier family 22 member 4	transporter
Nicotine	Cytochrome P450 1A1	enzyme
Nicotine	Cytochrome P450 1A2	enzyme
Nicotine	Cytochrome P450 2C19	enzyme
Nicotine	Cytochrome P450 2C8	enzyme
Nicotine	Cytochrome P450 2C9	enzyme
Nicotine	Cytochrome P450 2D6	enzyme
Nicotine	Cytochrome P450 3A4	enzyme
Nicotine	Amine oxidase [flavin-containing] A	enzyme
Nicotine	Amine oxidase [flavin-containing] B	enzyme
Nicotine	Cytochrome P450 19A1	target
Nicotine	Choline O-acetyltransferase	target
Carmustine	Glutathione reductase, mitochondrial	target
Carmustine	DNA	target
Carmustine	RNA	target
Lomefloxacin	DNA gyrase subunit A	target
Lomefloxacin	DNA topoisomerase 4 subunit A	target
Lomefloxacin	DNA topoisomerase 2-alpha	target
Lomefloxacin	Cytochrome P450 1A2	enzyme
Lomefloxacin	Solute carrier family 22 member 5	transporter
Lomefloxacin	Canalicular multispecific organic anion transporter 1	transporter
Hesperetin	Microsomal triglyceride transfer protein large subunit	target
Hesperetin	Sterol O-acyltransferase 1	target
Hesperetin	Sterol O-acyltransferase 2	target
Hesperetin	Cytochrome P450 1A2	enzyme
Hesperetin	ATP-binding cassette sub-family G member 2	transporter
Hesperetin	Sex hormone-binding globulin	target
Leflunomide	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Leflunomide	Cytochrome P450 1A2	enzyme
Leflunomide	Cytochrome P450 2C9	enzyme
Leflunomide	Aryl hydrocarbon receptor	target
Leflunomide	Protein-tyrosine kinase 2-beta	target
Leflunomide	ATP-binding cassette sub-family G member 2	transporter
Rofecoxib	Prostaglandin G/H synthase 2	target
Rofecoxib	Elastin	target
Rofecoxib	Cytochrome P450 3A4	enzyme
Rofecoxib	Cytochrome P450 1A2	enzyme
Rofecoxib	Multidrug resistance-associated protein 4	transporter
Rofecoxib	Prostaglandin G/H synthase 1	enzyme
Rofecoxib	Cytochrome P450 2C8	enzyme
Rofecoxib	Cytochrome P450 2C9	enzyme
Thiabendazole	Fumarate reductase flavoprotein subunit	target
Thiabendazole	Cytochrome P450 1A2	enzyme
Thiabendazole	Cytochrome P450 1A1	enzyme
Nifedipine	Cytochrome P450 3A4	enzyme
Nifedipine	Cytochrome P450 2E1	enzyme
Nifedipine	Cytochrome P450 2D6	enzyme
Nifedipine	Calmodulin	target
Nifedipine	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Nifedipine	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Nifedipine	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Nifedipine	Voltage-dependent L-type calcium channel subunit beta-2	target
Nifedipine	Potassium voltage-gated channel subfamily D member 3	target
Nifedipine	Voltage-dependent T-type calcium channel	target
Nifedipine	Cytochrome P450 1A2	enzyme
Nifedipine	Cytochrome P450 2A6	enzyme
Nifedipine	Cytochrome P450 2C8	enzyme
Nifedipine	Canalicular multispecific organic anion transporter 2	transporter
Nifedipine	P-glycoprotein 1	transporter
Nifedipine	Canalicular multispecific organic anion transporter 1	transporter
Nifedipine	Cytochrome P450 1A1	enzyme
Nifedipine	Cytochrome P450 2B6	enzyme
Nifedipine	Nuclear receptor subfamily 1 group I member 2	target
Nifedipine	Solute carrier organic anion transporter family member 1B1	transporter
Nifedipine	Bile salt export pump	transporter
Nifedipine	Cytochrome P450 2C9	enzyme
Nifedipine	Serum albumin	carrier
Nifedipine	alpha1-acid glycoprotein	carrier
Nifedipine	Cytochrome P450 3A5	enzyme
Primaquine	Cytochrome P450 1A1	enzyme
Primaquine	Cytochrome P450 1A2	enzyme
Primaquine	Cytochrome P450 3A4	enzyme
Primaquine	Keratin, type II cytoskeletal 7	target
Primaquine	Cytochrome P450 1B1	enzyme
Primaquine	Cytochrome P450 2D6	enzyme
Primaquine	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Primaquine	Fe(II)-protoporphyrin IX	target
Primaquine	P-glycoprotein 1	transporter
Etoricoxib	Prostaglandin G/H synthase 2	target
Etoricoxib	Cytochrome P450 3A4	enzyme
Etoricoxib	Cytochrome P450 2C9	enzyme
Etoricoxib	Cytochrome P450 2D6	enzyme
Etoricoxib	Cytochrome P450 1A2	enzyme
Etoricoxib	Cytochrome P450 2C19	enzyme
Etoricoxib	Cytochrome P450 2E1	enzyme
Praziquantel	Schistosome calcium ion (Ca2+) channels	target
Praziquantel	Cytochrome P450 3A4	enzyme
Praziquantel	Cytochrome P450 1A2	enzyme
Praziquantel	Cytochrome P450 2C19	enzyme
Praziquantel	Cytochrome P450 3A43	enzyme
Praziquantel	Cytochrome P450 3A5	enzyme
Praziquantel	Cytochrome P450 3A7	enzyme
Triamterene	Amiloride-sensitive sodium channel subunit gamma	target
Triamterene	Amiloride-sensitive sodium channel subunit alpha	target
Triamterene	Amiloride-sensitive sodium channel subunit beta	target
Triamterene	Amiloride-sensitive sodium channel subunit delta	target
Triamterene	Cytochrome P450 1A2	enzyme
Dasatinib	Tyrosine-protein kinase ABL1	target
Dasatinib	Tyrosine-protein kinase ABL2	target
Dasatinib	Proto-oncogene tyrosine-protein kinase Src	target
Dasatinib	Tyrosine-protein kinase Fyn	target
Dasatinib	Tyrosine-protein kinase Lck	target
Dasatinib	Tyrosine-protein kinase Yes	target
Dasatinib	Mast/stem cell growth factor receptor Kit	target
Dasatinib	Platelet-derived growth factor receptor beta	target
Dasatinib	Ephrin type-A receptor 2	target
Dasatinib	Signal transducer and activator of transcription 5B	target
Dasatinib	Cytochrome P450 3A4	enzyme
Dasatinib	P-glycoprotein 1	transporter
Dasatinib	ATP-binding cassette sub-family G member 2	transporter
Dasatinib	Cytochrome P450 1A1	enzyme
Dasatinib	Cytochrome P450 1A2	enzyme
Dasatinib	Cytochrome P450 1B1	enzyme
Dasatinib	Cytochrome P450 3A5	enzyme
Dasatinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Dasatinib	Tyrosine-protein kinase BTK	target
Dasatinib	Nuclear receptor subfamily 4 group A member 3	target
Dasatinib	Breakpoint cluster region protein	target
Dasatinib	Tyrosine-protein kinase CSK	target
Dasatinib	Ephrin type-A receptor 5	target
Dasatinib	Ephrin type-B receptor 4	target
Dasatinib	Tyrosine-protein kinase Fgr	target
Dasatinib	Tyrosine-protein kinase FRK	target
Dasatinib	Heat shock cognate 71 kDa protein	target
Dasatinib	Tyrosine-protein kinase Lyn	target
Dasatinib	Mitogen-activated protein kinase kinase kinase MLT	target
Dasatinib	Mitogen-activated protein kinase 14	target
Dasatinib	Amidophosphoribosyltransferase	target
Benzyl alcohol	Cytochrome P450 2C8	enzyme
Benzyl alcohol	Cytochrome P450 1A1	enzyme
Benzyl alcohol	Aldehyde dehydrogenase, mitochondrial	enzyme
Benzyl alcohol	Cytochrome P450 1A2	enzyme
Benzyl alcohol	Cytochrome P450 2E1	enzyme
Benzyl alcohol	Cytochrome P450 2D6	enzyme
Capsaicin	Cytochrome P450 3A4	enzyme
Capsaicin	Prostaglandin G/H synthase 2	enzyme
Capsaicin	Myeloperoxidase	enzyme
Capsaicin	Cytochrome P450 1A2	enzyme
Capsaicin	Cytochrome P450 2E1	enzyme
Capsaicin	Amine oxidase [flavin-containing] A	enzyme
Capsaicin	Dopamine beta-hydroxylase	enzyme
Capsaicin	Glutamine synthetase	enzyme
Capsaicin	Cholinesterase	enzyme
Capsaicin	Transient receptor potential cation channel subfamily V member 1	target
Capsaicin	Prohibitin-2	target
Binimetinib	UDP-glucuronosyltransferase 1-1	enzyme
Binimetinib	Cytochrome P450 1A2	enzyme
Binimetinib	Cytochrome P450 2C19	enzyme
Binimetinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Binimetinib	Serum albumin	carrier
Binimetinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Binimetinib	ATP-binding cassette sub-family G member 2	transporter
Binimetinib	P-glycoprotein 1	transporter
Azathioprine	Thiopurine S-methyltransferase	enzyme
Azathioprine	Xanthine dehydrogenase/oxidase	enzyme
Azathioprine	Glutathione S-transferase A1	enzyme
Azathioprine	Glutathione S-transferase A2	enzyme
Azathioprine	Glutathione S-transferase Mu 1	enzyme
Azathioprine	Ras-related C3 botulinum toxin substrate 1	target
Azathioprine	Cytochrome P450 1A2	enzyme
Azathioprine	Hypoxanthine-guanine phosphoribosyltransferase	enzyme
Azathioprine	Nucleotide triphosphate diphosphatase NUDT15	enzyme
Azathioprine	Equilibrative nucleoside transporter 2	transporter
Azathioprine	Solute carrier family 28 member 3	transporter
Azathioprine	P-glycoprotein 1	transporter
Azathioprine	Solute carrier family 43 member 3	transporter
Azathioprine	Serum albumin	carrier
Azathioprine	Inosine-5'-monophosphate dehydrogenase 1	enzyme
Azathioprine	Inosine-5'-monophosphate dehydrogenase 2	enzyme
Azathioprine	GMP synthase [glutamine-hydrolyzing]	enzyme
Azathioprine	Inosine triphosphate pyrophosphatase	enzyme
8-azaguanine	Purine nucleoside phosphorylase	target
8-azaguanine	Cytochrome P450 1A2	enzyme
9-Deazaguanine	Hypoxanthine-guanine phosphoribosyltransferase	target
9-Deazaguanine	Cytochrome P450 1A2	enzyme
9-Methylguanine	Dihydroneopterin aldolase	target
9-Methylguanine	Cytochrome P450 1A2	enzyme
Disopyramide	Sodium channel protein type 5 subunit alpha	target
Disopyramide	Alpha-1-acid glycoprotein 1	carrier
Disopyramide	Cytochrome P450 3A4	enzyme
Disopyramide	Muscarinic acetylcholine receptor M1	target
Disopyramide	Muscarinic acetylcholine receptor M2	target
Disopyramide	Muscarinic acetylcholine receptor M3	target
Disopyramide	Potassium voltage-gated channel subfamily D member 2	target
Disopyramide	Potassium voltage-gated channel subfamily D member 3	target
Disopyramide	Solute carrier family 22 member 2	transporter
Disopyramide	Solute carrier family 22 member 1	transporter
Disopyramide	Potassium voltage-gated channel subfamily H member 2	target
Disopyramide	Alpha-1-acid glycoprotein 2	target
Disopyramide	Cytochrome P450 1A2	enzyme
Alosetron	5-hydroxytryptamine receptor 3A	target
Alosetron	Cytochrome P450 1A2	enzyme
Alosetron	Cytochrome P450 2C9	enzyme
Alosetron	Cytochrome P450 3A4	enzyme
Alosetron	Cytochrome P450 2E1	enzyme
Sorafenib	Serine/threonine-protein kinase B-raf	target
Sorafenib	Receptor-type tyrosine-protein kinase FLT3	target
Sorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Sorafenib	Vascular endothelial growth factor receptor 3	target
Sorafenib	Platelet-derived growth factor receptor beta	target
Sorafenib	Mast/stem cell growth factor receptor Kit	target
Sorafenib	Vascular endothelial growth factor receptor 2	target
Sorafenib	Cytochrome P450 3A4	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Sorafenib	Cytochrome P450 2B6	enzyme
Sorafenib	Cytochrome P450 2C8	enzyme
Sorafenib	Cytochrome P450 3A5	enzyme
Sorafenib	Cytochrome P450 3A7	enzyme
Sorafenib	Cytochrome P450 2C9	enzyme
Sorafenib	Multidrug resistance-associated protein 4	transporter
Sorafenib	P-glycoprotein 1	transporter
Sorafenib	Canalicular multispecific organic anion transporter 1	transporter
Sorafenib	ATP-binding cassette sub-family G member 2	transporter
Sorafenib	Cytochrome P450 1A2	enzyme
Sorafenib	Cytochrome P450 2C19	enzyme
Sorafenib	Cytochrome P450 2D6	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Sorafenib	RalA-binding protein 1	transporter
Sorafenib	Fibroblast growth factor receptor 1	target
Sorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Sorafenib	Vascular endothelial growth factor receptor 1	target
Sorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Agomelatine	5-hydroxytryptamine receptor 2C	target
Agomelatine	Melatonin receptor type 1B	target
Agomelatine	Melatonin receptor type 1A	target
Agomelatine	Cytochrome P450 2C9	enzyme
Agomelatine	Cytochrome P450 1A2	enzyme
Tocainide	Sodium channel protein type 5 subunit alpha	target
Tocainide	Serum albumin	carrier
Tocainide	Cytochrome P450 1A2	enzyme
Triclabendazole	Cytochrome P450 1A2	enzyme
Triclabendazole	Cytochrome P450 2C9	enzyme
Triclabendazole	Excretory Secretory (ES) proteins	target
Triclabendazole	Cytochrome P450 3A4	enzyme
Triclabendazole	Cytochrome P450 1A1	enzyme
Triclabendazole	Cytochrome P450 1B1	enzyme
Triclabendazole	Cytochrome P450 2C19	enzyme
Triclabendazole	Cytochrome P450 2D6	enzyme
Triclabendazole	Cytochrome P450 2A6	enzyme
Triclabendazole	Cytochrome P450 2C8	enzyme
Triclabendazole	Cytochrome P450 2B6	enzyme
Dapagliflozin	Sodium/glucose cotransporter 2	target
Dapagliflozin	Cytochrome P450 1A1	enzyme
Dapagliflozin	Cytochrome P450 1A2	enzyme
Dapagliflozin	Cytochrome P450 2A6	enzyme
Dapagliflozin	Cytochrome P450 2C9	enzyme
Dapagliflozin	Cytochrome P450 2D6	enzyme
Dapagliflozin	Cytochrome P450 3A4	enzyme
Dapagliflozin	UDP-glucuronosyltransferase 1-9	enzyme
Dapagliflozin	UDP-glucuronosyltransferase 2B4	enzyme
Dapagliflozin	UDP-glucuronosyltransferase 2B7	enzyme
Dapagliflozin	P-glycoprotein 1	transporter
Apremilast	Phosphodiesterase isozyme 4	target
Apremilast	Cytochrome P450 3A4	enzyme
Apremilast	Cytochrome P450 2A6	enzyme
Apremilast	Cytochrome P450 1A2	enzyme
Apremilast	P-glycoprotein 1	transporter
Paroxetine	Sodium-dependent serotonin transporter	target
Paroxetine	Sodium-dependent noradrenaline transporter	target
Paroxetine	5-hydroxytryptamine receptor 2A	target
Paroxetine	Cytochrome P450 2D6	enzyme
Paroxetine	Cytochrome P450 2C9	enzyme
Paroxetine	P-glycoprotein 1	transporter
Paroxetine	Cytochrome P450 2B6	enzyme
Paroxetine	Cytochrome P450 1A2	enzyme
Paroxetine	Cytochrome P450 3A4	enzyme
Paroxetine	Alpha-1 adrenergic receptors	target
Paroxetine	Alpha-2 adrenergic receptors	target
Paroxetine	Beta adrenergic receptor	target
Paroxetine	Dopamine D2 receptor	target
Paroxetine	Histamine H1 receptor	target
Paroxetine	Serotonin Receptors	target
Paroxetine	Muscarinic acetylcholine receptor	target
Paroxetine	5-hydroxytryptamine receptor 2B	target
Paroxetine	D(1) dopamine receptor	target
Paroxetine	Cytochrome P450 2C19	enzyme
Tamoxifen	Estrogen receptor alpha	target
Tamoxifen	Estrogen receptor beta	target
Tamoxifen	Cytochrome P450 2C9	enzyme
Tamoxifen	Cytochrome P450 3A4	enzyme
Tamoxifen	Cytochrome P450 2D6	enzyme
Tamoxifen	Cytochrome P450 2C8	enzyme
Tamoxifen	Cytochrome P450 2B6	enzyme
Tamoxifen	Liver carboxylesterase 1	enzyme
Tamoxifen	Cytochrome P450 3A5	enzyme
Tamoxifen	Cytochrome P450 1A1	enzyme
Tamoxifen	Cytochrome P450 1B1	enzyme
Tamoxifen	Cytochrome P450 2C19	enzyme
Tamoxifen	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Tamoxifen	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Tamoxifen	Cytochrome P450 3A7	enzyme
Tamoxifen	P-glycoprotein 1	transporter
Tamoxifen	ATP-binding cassette sub-family G member 2	transporter
Tamoxifen	Cytochrome P450 19A1	enzyme
Tamoxifen	Cytochrome P450 2A6	enzyme
Tamoxifen	Cytochrome P450 2E1	enzyme
Tamoxifen	UDP-glucuronosyltransferase 1-10	enzyme
Tamoxifen	Sulfotransferase 1A1	enzyme
Tamoxifen	Canalicular multispecific organic anion transporter 1	transporter
Tamoxifen	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	target
Tamoxifen	Protein kinase C	target
Tamoxifen	Androgen receptor	target
Tamoxifen	Potassium voltage-gated channel subfamily H member 2	target
Tamoxifen	Nuclear receptor subfamily 1 group I member 2	target
Tamoxifen	Estrogen-related receptor gamma	target
Tamoxifen	Sex hormone-binding globulin	target
Tamoxifen	Bile salt export pump	transporter
Tamoxifen	Thyroxine-binding globulin	carrier
Tamoxifen	Bile salt sulfotransferase	enzyme
Tamoxifen	Cytochrome P450 1A2	enzyme
Tamoxifen	UDP-glucuronosyltransferase 2B7	enzyme
Tamoxifen	UDP-glucuronosyltransferase 2B17	enzyme
Tamoxifen	Estrogen sulfotransferase	enzyme
Tamoxifen	ATP-binding cassette sub-family A member 1	transporter
Tamoxifen	Mitogen-activated protein kinase 8	target
Tamoxifen	Serum albumin	carrier
Istradefylline	Cytochrome P450 1A1	enzyme
Istradefylline	Cytochrome P450 3A4	enzyme
Istradefylline	Cytochrome P450 3A5	enzyme
Istradefylline	Cytochrome P450 1A2	enzyme
Istradefylline	Cytochrome P450 2B6	enzyme
Istradefylline	Cytochrome P450 2C8	enzyme
Istradefylline	Cytochrome P450 2C9	enzyme
Istradefylline	Cytochrome P450 2C18	enzyme
Istradefylline	Cytochrome P450 2D6	enzyme
Istradefylline	Cytochrome P450 3A Subfamily	enzyme
Istradefylline	P-glycoprotein 1	transporter
Istradefylline	Adenosine receptor A2a	target
Istradefylline	Adenosine receptor A1	target
Istradefylline	Serum albumin	carrier
Istradefylline	alpha1-acid glycoprotein	carrier
Istradefylline	ATP-binding cassette sub-family G member 2	transporter
Istradefylline	Solute carrier organic anion transporter family member 1B1	transporter
Istradefylline	Solute carrier organic anion transporter family member 1B3	transporter
Istradefylline	Solute carrier family 22 member 6	transporter
Istradefylline	POU domain, class 2, transcription factor 2	transporter
Istradefylline	Multidrug and toxin extrusion protein 1	transporter
Istradefylline	Multidrug and toxin extrusion protein 2	transporter
Efavirenz	Cytochrome P450 2B6	enzyme
Efavirenz	Cytochrome P450 3A4	enzyme
Efavirenz	Cytochrome P450 2C19	enzyme
Efavirenz	Cytochrome P450 2C9	enzyme
Efavirenz	Cytochrome P450 1A2	enzyme
Efavirenz	Cytochrome P450 2D6	enzyme
Efavirenz	Reverse transcriptase/RNaseH	target
Efavirenz	Cytochrome P450 2C8	enzyme
Efavirenz	Serum albumin	carrier
Efavirenz	Cytochrome P450 3A5	enzyme
Efavirenz	Cytochrome P450 3A7	enzyme
Efavirenz	UDP-glucuronosyltransferase 1-1	enzyme
Efavirenz	Bile salt export pump	transporter
Efavirenz	Solute carrier family 22 member 1	transporter
Metoclopramide	Muscarinic acetylcholine receptor M1	target
Metoclopramide	Dopamine D2 receptor	target
Metoclopramide	Cytochrome P450 2D6	enzyme
Metoclopramide	5-hydroxytryptamine receptor 4	target
Metoclopramide	5-hydroxytryptamine receptor 3A	target
Metoclopramide	Cytochrome P450 3A4	enzyme
Metoclopramide	Cytochrome P450 1A2	enzyme
Metoclopramide	P-glycoprotein 1	transporter
Metoclopramide	Alpha-1-acid glycoprotein 1	carrier
Loratadine	Histamine H1 receptor	target
Loratadine	Cytochrome P450 3A4	enzyme
Loratadine	Cytochrome P450 2C19	enzyme
Loratadine	Cytochrome P450 2D6	enzyme
Loratadine	Cytochrome P450 2C8	enzyme
Loratadine	P-glycoprotein 1	transporter
Loratadine	Potassium voltage-gated channel subfamily H member 2	target
Loratadine	Bile salt export pump	transporter
Loratadine	Cytochrome P450 1A1	enzyme
Loratadine	Cytochrome P450 1A2	enzyme
Loratadine	Cytochrome P450 2B6	enzyme
Loratadine	Cytochrome P450 2C9	enzyme
Loratadine	Cytochrome P450 3A5	enzyme
Loratadine	UDP-glucuronosyltransferase 2B10	enzyme
Loratadine	UDP-glucuronosyltransferase 1-1	enzyme
Loratadine	UDP-glucuronosyltransferase 1-3	enzyme
Loratadine	UDP-glucuronosyltransferase 2B15	enzyme
GTS-21	Neuronal acetylcholine receptor subunit alpha-7	target
GTS-21	Cytochrome P450 1A2	enzyme
GTS-21	Cytochrome P450 2E1	enzyme
Bicifadine	Sodium-dependent noradrenaline transporter	target
Bicifadine	Sodium-dependent serotonin transporter	target
Bicifadine	Dopamine D2 receptor	target
Bicifadine	Cytochrome P450 2D6	enzyme
Bicifadine	Amine oxidase [flavin-containing] B	enzyme
Bicifadine	Cytochrome P450 1A2	enzyme
Bicifadine	Amine oxidase [flavin-containing] A	enzyme
Vortioxetine	Sodium-dependent serotonin transporter	target
Vortioxetine	5-hydroxytryptamine receptor 3A	target
Vortioxetine	5-hydroxytryptamine receptor 7	target
Vortioxetine	5-hydroxytryptamine receptor 1B	target
Vortioxetine	5-hydroxytryptamine receptor 1A	target
Vortioxetine	Beta-1 adrenergic receptor	target
Vortioxetine	Sodium-dependent noradrenaline transporter	target
Vortioxetine	Cytochrome P450 2D6	enzyme
Vortioxetine	Cytochrome P450 3A4	enzyme
Vortioxetine	Cytochrome P450 3A5	enzyme
Vortioxetine	Cytochrome P450 2C19	enzyme
Vortioxetine	Cytochrome P450 2C9	enzyme
Vortioxetine	Cytochrome P450 2A6	enzyme
Vortioxetine	Cytochrome P450 2C8	enzyme
Vortioxetine	Cytochrome P450 2B6	enzyme
Formoterol	Beta-2 adrenergic receptor	target
Formoterol	Beta-1 adrenergic receptor	target
Formoterol	Beta-3 adrenergic receptor	target
Formoterol	Cytochrome P450 2D6	enzyme
Formoterol	Cytochrome P450 2C19	enzyme
Formoterol	Cytochrome P450 2C9	enzyme
Formoterol	Cytochrome P450 2A6	enzyme
Formoterol	UDP-glucuronosyltransferase 1A1	enzyme
Formoterol	UDP-glucuronosyltransferase 1-8	enzyme
Formoterol	UDP-glucuronosyltransferase 1-9	enzyme
Formoterol	UDP-glucuronosyltransferase 2B7	enzyme
Formoterol	UDP-glucuronosyltransferase 2B15	enzyme
Formoterol	Solute carrier family 22 member 1	transporter
Formoterol	Solute carrier family 22 member 4	transporter
Formoterol	Solute carrier family 22 member 5	transporter
Formoterol	Solute carrier family 22 member 3	transporter
Formoterol	Serum albumin	carrier
Letrozole	Cytochrome P450 19A1	target
Letrozole	Cytochrome P450 3A4	enzyme
Letrozole	Cytochrome P450 2A6	enzyme
Letrozole	Cytochrome P450 19A1	enzyme
Letrozole	Cytochrome P450 2C19	enzyme
Letrozole	UDP-glucuronosyltransferase 2B7	enzyme
Letrozole	Serum albumin	carrier
Letrozole	P-glycoprotein 1	transporter
Halothane	Gamma-aminobutyric acid receptor subunit alpha-1	target
Halothane	Glycine receptor subunit alpha-1	target
Halothane	Calcium-activated potassium channel subunit alpha-1	target
Halothane	NADH-ubiquinone oxidoreductase chain 1	target
Halothane	Intermediate conductance calcium-activated potassium channel protein 4	target
Halothane	Rhodopsin	target
Halothane	G protein-activated inward rectifier potassium channel 2	target
Halothane	G protein-activated inward rectifier potassium channel 1	target
Halothane	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	target
Halothane	Neuropeptide S receptor	target
Halothane	Cytochrome P450 2E1	enzyme
Halothane	Cytochrome P450 2A6	enzyme
Halothane	Cytochrome P450 3A4	enzyme
Halothane	Glutamate receptor ionotropic, NMDA 3A	target
Halothane	Glutamate receptor ionotropic, NMDA 3B	target
Halothane	Glutamate receptor ionotropic, NMDA 2A	target
Halothane	Potassium channel subfamily K member 3	target
Halothane	Potassium channel subfamily K member 9	target
Halothane	Serum albumin	carrier
Halothane	Cytochrome P450 2B6	enzyme
Halothane	Cytochrome P450 2C9	enzyme
Halothane	GABA(A) Receptor	target
Halothane	Plasma membrane calcium-transporting ATPase	target
Ifosfamide	Cytochrome P450 2B6	enzyme
Ifosfamide	DNA	target
Ifosfamide	Cytochrome P450 3A4	enzyme
Ifosfamide	Cytochrome P450 3A5	enzyme
Ifosfamide	Cytochrome P450 2C9	enzyme
Ifosfamide	Cytochrome P450 2C8	enzyme
Ifosfamide	Cytochrome P450 2A6	enzyme
Ifosfamide	Cytochrome P450 2C19	enzyme
Ifosfamide	Cytochrome P450 2C18	enzyme
Ifosfamide	Prostaglandin G/H synthase 1	enzyme
Ifosfamide	Nuclear receptor subfamily 1 group I member 2	target
Valproic acid	Histone deacetylase 9	target
Valproic acid	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	target
Valproic acid	Cytochrome P450 2A6	enzyme
Valproic acid	Cytochrome P450 2B6	enzyme
Valproic acid	Cytochrome P450 2C9	enzyme
Valproic acid	Solute carrier family 22 member 5	transporter
Valproic acid	Solute carrier family 22 member 6	transporter
Valproic acid	Solute carrier family 22 member 8	transporter
Valproic acid	Monocarboxylate transporter 1	transporter
Valproic acid	Solute carrier family 22 member 7	transporter
Valproic acid	Cytochrome P450 3A5	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-9	enzyme
Valproic acid	Prostaglandin G/H synthase 1	enzyme
Valproic acid	Cytochrome P450 1A2	enzyme
Valproic acid	Cytochrome P450 2C19	enzyme
Valproic acid	Cytochrome P450 3A4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-8	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-10	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-6	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-3	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B7	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B15	enzyme
Valproic acid	2-oxoglutarate dehydrogenase, mitochondrial	target
Valproic acid	Succinate-semialdehyde dehydrogenase, mitochondrial	target
Valproic acid	Sodium channel protein	target
Valproic acid	Histone deacetylase 2	target
Valproic acid	Peroxisome proliferator-activated receptor alpha	target
Valproic acid	Peroxisome proliferator-activated receptor delta	target
Valproic acid	Peroxisome proliferator-activated receptor gamma	target
Valproic acid	Serum albumin	carrier
Valproic acid	UDP-glucuronosyltransferase 1-1	enzyme
Valproic acid	Solute carrier organic anion transporter family member 2B1	transporter
Valproic acid	Histone deacetylase	target
Valproic acid	Cyclin-dependent kinase inhibitor 1	target
Valproic acid	Hepatocyte growth factor	target
Valproic acid	Ornithine decarboxylase	target
Valproic acid	Programmed cell death 1 ligand 1	target
Nevirapine	Cytochrome P450 3A4	enzyme
Nevirapine	Cytochrome P450 2B6	enzyme
Nevirapine	Cytochrome P450 3A5	enzyme
Nevirapine	Cytochrome P450 2C9	enzyme
Nevirapine	Cytochrome P450 2A6	enzyme
Nevirapine	Cytochrome P450 2D6	enzyme
Nevirapine	Reverse transcriptase/RNaseH	target
Nevirapine	Serum albumin	carrier
Nevirapine	Cytochrome P450 1A2	enzyme
Nevirapine	Solute carrier family 22 member 1	transporter
Nevirapine	Cytochrome P450 3A7	enzyme
Montelukast	Cysteinyl leukotriene receptor 1	target
Montelukast	Arachidonate 5-lipoxygenase	target
Montelukast	Cytochrome P450 3A4	enzyme
Montelukast	Cytochrome P450 2C9	enzyme
Montelukast	Cytochrome P450 2C8	enzyme
Montelukast	Solute carrier organic anion transporter family member 2B1	transporter
Montelukast	Prostaglandin G/H synthase 1	enzyme
Montelukast	Cytochrome P450 2A6	enzyme
Cisapride	5-hydroxytryptamine receptor 4	target
Cisapride	5-hydroxytryptamine receptor 3A	target
Cisapride	Potassium voltage-gated channel subfamily H member 2	target
Cisapride	5-hydroxytryptamine receptor 2A	target
Cisapride	Cytochrome P450 3A4	enzyme
Cisapride	Cytochrome P450 3A5	enzyme
Cisapride	Cytochrome P450 3A7	enzyme
Cisapride	Cytochrome P450 2A6	enzyme
Cisapride	Cytochrome P450 2B6	enzyme
Cisapride	Cytochrome P450 2C19	enzyme
Cisapride	Cytochrome P450 2C8	enzyme
Cisapride	Cytochrome P450 2C9	enzyme
Cisapride	Cytochrome P450 2D6	enzyme
Clomethiazole	Gamma-aminobutyric acid receptor subunit alpha-1	target
Clomethiazole	Cytochrome P450 2A6	enzyme
Clomethiazole	Cytochrome P450 2B6	enzyme
Clomethiazole	Cytochrome P450 2C19	enzyme
Clomethiazole	Cytochrome P450 3A4	enzyme
Cyclophosphamide	DNA	target
Cyclophosphamide	Cytochrome P450 2B6	enzyme
Cyclophosphamide	Cytochrome P450 2C9	enzyme
Cyclophosphamide	Cytochrome P450 3A4	enzyme
Cyclophosphamide	Cytochrome P450 2C19	enzyme
Cyclophosphamide	Cytochrome P450 2A6	enzyme
Cyclophosphamide	Cytochrome P450 2C18	enzyme
Cyclophosphamide	Cytochrome P450 2C8	enzyme
Cyclophosphamide	Cytochrome P450 3A5	enzyme
Cyclophosphamide	Nuclear receptor subfamily 1 group I member 2	target
Flunitrazepam	Cytochrome P450 2C19	enzyme
Flunitrazepam	UDP-glucuronosyltransferase 2B7	enzyme
Flunitrazepam	Cytochrome P450 2A6	enzyme
Flunitrazepam	Cytochrome P450 2B6	enzyme
Flunitrazepam	Cytochrome P450 2C9	enzyme
Flunitrazepam	Cytochrome P450 3A4	enzyme
Flunitrazepam	Cytochrome P450 2E1	enzyme
Flunitrazepam	UDP-glucuronosyltransferase 1-1	enzyme
Flunitrazepam	UDP-glucuronosyltransferase 1-3	enzyme
Flunitrazepam	GABA(A) Receptor	target
Flunitrazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Sevoflurane	NADH-ubiquinone oxidoreductase chain 1	target
Sevoflurane	Glycine receptor subunit alpha-1	target
Sevoflurane	Glutamate receptor 1	target
Sevoflurane	Cytochrome P450 2E1	enzyme
Sevoflurane	Serum albumin	carrier
Sevoflurane	Cytochrome P450 2A6	enzyme
Sevoflurane	Cytochrome P450 2B6	enzyme
Sevoflurane	Cytochrome P450 3A4	enzyme
Sevoflurane	GABA(A) Receptor	target
Sevoflurane	Mitochondrial potassium channel	target
Sevoflurane	Calcium transporting ATPases	target
Zidovudine	Serum albumin	carrier
Zidovudine	Cytochrome P450 2A6	enzyme
Zidovudine	Cytochrome P450 2C9	enzyme
Zidovudine	Cytochrome P450 3A4	enzyme
Zidovudine	Reverse transcriptase/RNaseH	target
Zidovudine	Solute carrier family 22 member 2	transporter
Zidovudine	Solute carrier family 22 member 6	transporter
Zidovudine	Solute carrier family 22 member 7	transporter
Zidovudine	Solute carrier family 22 member 8	transporter
Zidovudine	Solute carrier family 22 member 11	transporter
Zidovudine	Sodium/nucleoside cotransporter 1	transporter
Zidovudine	Equilibrative nucleoside transporter 2	transporter
Zidovudine	P-glycoprotein 1	transporter
Zidovudine	Multidrug resistance-associated protein 4	transporter
Zidovudine	Multidrug resistance-associated protein 5	transporter
Zidovudine	ATP-binding cassette sub-family G member 2	transporter
Zidovudine	Telomerase reverse transcriptase	target
Zidovudine	Thymidine kinase, cytosolic	enzyme
Zidovudine	UDP-glucuronosyltransferase 2B7	enzyme
Zidovudine	UDP-glucuronosyltransferase 1-1	enzyme
Flurazepam	Cytochrome P450 3A4	enzyme
Flurazepam	P-glycoprotein 1	transporter
Flurazepam	Cytochrome P450 2E1	enzyme
Flurazepam	Cytochrome P450 2A6	enzyme
Flurazepam	Solute carrier family 22 member 2	transporter
Flurazepam	GABA(A) Receptor	target
Flurazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Tretinoin	Retinoic acid receptor gamma	target
Tretinoin	Retinoic acid receptor RXR-beta	target
Tretinoin	Retinal dehydrogenase 1	target
Tretinoin	Retinoic acid-induced protein 3	target
Tretinoin	Retinoic acid receptor RXR-gamma	target
Tretinoin	Retinal dehydrogenase 2	target
Tretinoin	Retinoic acid receptor responder protein 1	target
Tretinoin	Cytochrome P450 2C8	enzyme
Tretinoin	Cellular retinoic acid-binding protein 1	transporter
Tretinoin	Cellular retinoic acid-binding protein 2	transporter
Tretinoin	Cytochrome P450 2B6	enzyme
Tretinoin	Cytochrome P450 3A4	enzyme
Tretinoin	Cytochrome P450 3A5	enzyme
Tretinoin	Cytochrome P450 2A6	enzyme
Tretinoin	Cytochrome P450 3A7	enzyme
Tretinoin	Cytochrome P450 2C18	enzyme
Tretinoin	Cytochrome P450 2C9	enzyme
Tretinoin	Cytochrome P450 4A11	enzyme
Tretinoin	Cytochrome P450 1A1	enzyme
Tretinoin	Retinoic acid receptor alpha	target
Tretinoin	Retinoic acid receptor beta	target
Tretinoin	Lipocalin-1	target
Tretinoin	Odorant-binding protein 2a	target
Tretinoin	Retinol-binding protein 4	target
Tretinoin	Serum albumin	carrier
Tretinoin	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	target
Tretinoin	Retinoic acid receptor RXR-alpha	target
Tretinoin	Carcinoembryonic antigen	target
Tretinoin	UDP-glucuronosyltransferase 2B7	enzyme
Tretinoin	Cytochrome P450 2E1	enzyme
Tretinoin	Cytochrome P450 26A1	enzyme
Tretinoin	Cellular retinoic acid-binding protein 1	target
Arformoterol	Beta-2 adrenergic receptor	target
Arformoterol	Cytochrome P450 2D6	enzyme
Arformoterol	Cytochrome P450 2C19	enzyme
Arformoterol	Cytochrome P450 2A6	enzyme
Arformoterol	Cytochrome P450 2C9	enzyme
Tegafur-uracil	Cytochrome P450 2A6	enzyme
Tegafur-uracil	Dihydropyrimidine dehydrogenase [NADP(+)]	enzyme
Tegafur-uracil	Dihydropyrimidine dehydrogenase [NADP(+)]	target
Tegafur-uracil	Thymidylate synthase	target
Tegafur-uracil	RNA	target
Tegafur-uracil	DNA	target
Tegafur-uracil	Solute carrier family 22 member 7	transporter
Tegafur-uracil	Equilibrative nucleoside transporter 1	transporter
Tegafur-uracil	Equilibrative nucleoside transporter 2	transporter
Tegafur-uracil	Sodium/nucleoside cotransporter 1	transporter
Tegafur-uracil	Sodium/nucleoside cotransporter 2	transporter
Tegafur-uracil	Solute carrier family 28 member 3	transporter
Asunaprevir	Genome polyprotein	target
Asunaprevir	Cytochrome P450 3A4	enzyme
Asunaprevir	Cytochrome P450 3A5	enzyme
Asunaprevir	Cytochrome P450 2A6	enzyme
Asunaprevir	Cytochrome P450 2B6	enzyme
Asunaprevir	Cytochrome P450 2C9	enzyme
Asunaprevir	Cytochrome P450 2C19	enzyme
Asunaprevir	Cytochrome P450 2D6	enzyme
Asunaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Asunaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Asunaprevir	Solute carrier organic anion transporter family member 2B1	transporter
Asunaprevir	P-glycoprotein 1	transporter
Artesunate	Malaria protein EXP-1	target
Artesunate	Cytochrome P450 2A6	enzyme
Artesunate	UDP-glucuronosyltransferase 2B7	enzyme
Artesunate	UDP-glucuronosyltransferase 1-9	enzyme
Artesunate	ATP-binding cassette sub-family G member 2	transporter
Artesunate	P-glycoprotein 1	transporter
Artesunate	Solute carrier organic anion transporter family member 1B1	transporter
Artesunate	Solute carrier family 22 member 8	transporter
Artesunate	Serum albumin	carrier
Metronidazole	Oxygen-insensitive NADPH nitroreductase	target
Metronidazole	Cytochrome P450 2C9	enzyme
Metronidazole	Cytochrome P450 3A4	enzyme
Metronidazole	Cytochrome P450 2C8	enzyme
Metronidazole	UDP-glucuronosyltransferase 1-1	enzyme
Metronidazole	Anaerobic bacterial DNA	target
Metronidazole	Protozoal DNA	target
Metronidazole	P-glycoprotein 1	transporter
Metronidazole	Cytochrome P450 2A6	enzyme
Metronidazole	Cytochrome P450 3A5	enzyme
Metronidazole	Cytochrome P450 3A7	enzyme
Plitidepsin	Cytochrome P450 3A4	enzyme
Plitidepsin	Cytochrome P450 2A6	enzyme
Plitidepsin	Cytochrome P450 2E1	enzyme
Plitidepsin	Cytochrome P450 4A11	enzyme
Plitidepsin	Elongation factor 1-alpha 2	target
Bupropion	Sodium-dependent dopamine transporter	target
Bupropion	Sodium-dependent noradrenaline transporter	target
Bupropion	Cytochrome P450 2B6	enzyme
Bupropion	Cytochrome P450 2D6	enzyme
Bupropion	Alpha-1-acid glycoprotein 1	carrier
Bupropion	Neuronal acetylcholine receptor subunit alpha-3	target
Bupropion	Cytochrome P450 2C9	enzyme
Bupropion	Cytochrome P450 2E1	enzyme
Bupropion	Solute carrier family 22 member 2	transporter
Bupropion	5-hydroxytryptamine receptor 3A	target
Meperidine	Kappa-type opioid receptor	target
Meperidine	Cytochrome P450 2D6	enzyme
Meperidine	Cytochrome P450 2B6	enzyme
Meperidine	Glutamate receptor ionotropic, NMDA 1	target
Meperidine	Glutamate receptor ionotropic, NMDA 2B	target
Meperidine	Glutamate receptor ionotropic, NMDA 2A	target
Meperidine	Glutamate receptor ionotropic, NMDA 2C	target
Meperidine	Glutamate receptor ionotropic, NMDA 2D	target
Meperidine	Cytochrome P450 2C19	enzyme
Meperidine	Cytochrome P450 3A4	enzyme
Meperidine	Serum albumin	carrier
Meperidine	Alpha-1-acid glycoprotein 1	carrier
Meperidine	Muscarinic acetylcholine receptor	target
Meperidine	Mu-type opioid receptor	target
Meperidine	Sodium-dependent dopamine transporter	target
Meperidine	Sodium-dependent noradrenaline transporter	target
Meperidine	Sodium-dependent serotonin transporter	target
Meperidine	Liver carboxylesterase 1	target
Meperidine	Cytochrome P450 1A2	enzyme
Meperidine	P-glycoprotein 1	transporter
Propofol	Cytochrome P450 2B6	enzyme
Propofol	UDP-glucuronosyltransferase 1-1	enzyme
Propofol	UDP-glucuronosyltransferase 1-9	enzyme
Propofol	Gamma-aminobutyric acid receptor subunit beta-2	target
Propofol	Gamma-aminobutyric acid receptor subunit beta-3	target
Propofol	Serum albumin	carrier
Propofol	Sodium channel protein type 4 subunit alpha	target
Propofol	Sodium channel protein type 2 subunit alpha	target
Propofol	Fatty-acid amide hydrolase 1	enzyme
Propofol	Cytochrome P450 2C9	enzyme
Propofol	UDP-glucuronosyltransferase 1-8	enzyme
Propofol	Cytochrome P450 2E1	enzyme
Propofol	Cytochrome P450 1B1	enzyme
Propofol	Cytochrome P450 1A1	enzyme
Propofol	Cytochrome P450 1A2	enzyme
Propofol	Cytochrome P450 2C18	enzyme
Propofol	Cytochrome P450 2C19	enzyme
Propofol	Cytochrome P450 2C8	enzyme
Propofol	UDP-glucuronosyltransferase 1-6	enzyme
Propofol	GABA(A) Receptor	target
Propofol	P-glycoprotein 1	transporter
Ketamine	Glutamate receptor ionotropic, NMDA 3A	target
Ketamine	Neurokinin 1 receptor	target
Ketamine	Cytochrome P450 2B6	enzyme
Ketamine	Cytochrome P450 2C9	enzyme
Ketamine	Cytochrome P450 3A4	enzyme
Ketamine	Dopamine D2 receptor	target
Ketamine	Prostaglandin G/H synthase 1	enzyme
Ketamine	Cytochrome P450 2C8	enzyme
Ketamine	Delta-type opioid receptor	target
Ketamine	Sodium-dependent noradrenaline transporter	target
Ketamine	Kappa-type opioid receptor	target
Ketamine	Mu-type opioid receptor	target
Ketamine	Muscarinic acetylcholine receptor	target
Ketamine	5-hydroxytryptamine receptor 2	target
Ketamine	5-hydroxytryptamine receptor 1	target
Ketamine	5-hydroxytryptamine receptor 3A	target
Ketamine	Alpha-7 nicotinic cholinergic receptor subunit	target
Ketamine	Cholinesterase	target
Ketamine	Nitric oxide synthase, brain	target
Dosulepin	5-hydroxytryptamine receptor 1A	target
Dosulepin	5-hydroxytryptamine receptor 2A	target
Dosulepin	Cytochrome P450 2D6	enzyme
Dosulepin	Cytochrome P450 1A2	enzyme
Dosulepin	Cytochrome P450 2C19	enzyme
Dosulepin	Cytochrome P450 2C9	enzyme
Dosulepin	Histamine H1 receptor	target
Dosulepin	Muscarinic acetylcholine receptor M1	target
Dosulepin	Muscarinic acetylcholine receptor M2	target
Dosulepin	Muscarinic acetylcholine receptor M3	target
Dosulepin	Muscarinic acetylcholine receptor M4	target
Dosulepin	Muscarinic acetylcholine receptor M5	target
Dosulepin	Sodium-dependent noradrenaline transporter	target
Dosulepin	Sodium-dependent serotonin transporter	target
Dosulepin	Alpha-1 adrenergic receptors	target
Dosulepin	Alpha-2 adrenergic receptors	target
Trimipramine	Sodium-dependent serotonin transporter	target
Trimipramine	Sodium-dependent noradrenaline transporter	target
Trimipramine	Cytochrome P450 2D6	enzyme
Trimipramine	Sodium-dependent dopamine transporter	target
Trimipramine	5-hydroxytryptamine receptor 2A	target
Trimipramine	5-hydroxytryptamine receptor 1A	target
Trimipramine	Alpha-1A adrenergic receptor	target
Trimipramine	Alpha-1B adrenergic receptor	target
Trimipramine	Dopamine D2 receptor	target
Trimipramine	Alpha-2B adrenergic receptor	target
Trimipramine	Histamine H1 receptor	target
Trimipramine	Cytochrome P450 2C19	enzyme
Trimipramine	P-glycoprotein 1	transporter
Trimipramine	Cytochrome P450 2C9	enzyme
Trimipramine	5-hydroxytryptamine receptor 2C	target
Trimipramine	5-hydroxytryptamine receptor 3A	target
Trimipramine	5-hydroxytryptamine receptor 1D	target
Trimipramine	Alpha-2A adrenergic receptor	target
Trimipramine	D(1) dopamine receptor	target
Trimipramine	Beta adrenergic receptor	target
Trimipramine	Muscarinic acetylcholine receptor	target
Trimipramine	5-hydroxytryptamine receptor 1C	target
Ritonavir	Human immunodeficiency virus type 1 protease	target
Ritonavir	Cytochrome P450 2D6	enzyme
Ritonavir	Cytochrome P450 2C9	enzyme
Ritonavir	Cytochrome P450 2C19	enzyme
Ritonavir	Cytochrome P450 2B6	enzyme
Ritonavir	Cytochrome P450 2C8	enzyme
Ritonavir	P-glycoprotein 1	transporter
Ritonavir	Multidrug resistance-associated protein 1	transporter
Ritonavir	Canalicular multispecific organic anion transporter 1	transporter
Ritonavir	Solute carrier organic anion transporter family member 1A2	transporter
Ritonavir	ATP-binding cassette sub-family G member 2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1B1	transporter
Ritonavir	Cytochrome P450 1A2	enzyme
Ritonavir	Nuclear receptor subfamily 1 group I member 2	target
Ritonavir	Serum albumin	carrier
Ritonavir	Cytochrome P450 3A4	enzyme
Ritonavir	Cytochrome P450 3A5	enzyme
Ritonavir	Cytochrome P450 3A7	enzyme
Ritonavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Ritonavir	Solute carrier organic anion transporter family member 2B1	transporter
Ritonavir	Bile salt export pump	transporter
Ritonavir	Alpha-1-acid glycoprotein 1	carrier
Ritonavir	Solute carrier organic anion transporter family member 1B3	transporter
Loperamide	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	target
Loperamide	Mu-type opioid receptor	target
Loperamide	Calmodulin	target
Loperamide	Pro-opiomelanocortin	target
Loperamide	Delta-type opioid receptor	target
Loperamide	Cytochrome P450 3A4	enzyme
Loperamide	P-glycoprotein 1	transporter
Loperamide	Kappa-type opioid receptor	target
Loperamide	Cytochrome P450 2C8	enzyme
Loperamide	Cytochrome P450 2B6	enzyme
Loperamide	Cytochrome P450 2D6	enzyme
Loperamide	Potassium voltage-gated channel subfamily H member 2	target
Perhexiline	Carnitine O-palmitoyltransferase 1, liver isoform	target
Perhexiline	Carnitine O-palmitoyltransferase 2, mitochondrial	target
Perhexiline	Cytochrome P450 2D6	enzyme
Perhexiline	Cytochrome P450 2B6	enzyme
Perhexiline	Cytochrome P450 3A4	enzyme
Perhexiline	Potassium voltage-gated channel subfamily H member 2	target
Tramadol	Mu-type opioid receptor	target
Tramadol	Sodium-dependent noradrenaline transporter	target
Tramadol	5-hydroxytryptamine receptor 2C	target
Tramadol	Kappa-type opioid receptor	target
Tramadol	Sodium-dependent serotonin transporter	target
Tramadol	Cytochrome P450 2D6	enzyme
Tramadol	Delta-type opioid receptor	target
Tramadol	Cytochrome P450 3A4	enzyme
Tramadol	Cytochrome P450 2B6	enzyme
Tramadol	Alpha-7 nicotinic cholinergic receptor subunit	target
Tramadol	Muscarinic acetylcholine receptor M3	target
Tramadol	Muscarinic acetylcholine receptor M1	target
Tramadol	UDP-glucuronosyltransferase 1-1	enzyme
Tramadol	Neurokinin 1 receptor	target
Tramadol	Sodium channel protein type 2 subunit alpha	target
Tramadol	Transient receptor potential cation channel subfamily V member 1	target
Tramadol	NMDA receptor	target
Tramadol	Adenosine receptor A1	target
Tramadol	Alpha-2 adrenergic receptors	target
Sertraline	Sodium-dependent serotonin transporter	target
Sertraline	Cytochrome P450 2B6	enzyme
Sertraline	Cytochrome P450 2C19	enzyme
Sertraline	Cytochrome P450 2C9	enzyme
Sertraline	Cytochrome P450 2D6	enzyme
Sertraline	Sodium-dependent dopamine transporter	target
Sertraline	CYP2B protein	enzyme
Sertraline	Cytochrome P450 3A4	enzyme
Sertraline	Amine oxidase [flavin-containing] B	enzyme
Sertraline	Amine oxidase [flavin-containing] A	enzyme
Sertraline	P-glycoprotein 1	transporter
Sertraline	Serum albumin	carrier
Sertraline	Sigma receptor	target
Sertraline	Sodium-dependent noradrenaline transporter	target
Sertraline	Equilibrative nucleoside transporter 4	target
Sertraline	Cytochrome P450 2E1	enzyme
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	target
Methylphenobarbital	Cytochrome P450 2C19	enzyme
Methylphenobarbital	Cytochrome P450 2B6	enzyme
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-2	target
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-3	target
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-4	target
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-5	target
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-6	target
Methylphenobarbital	Neuronal acetylcholine receptor subunit alpha-4	target
Methylphenobarbital	Neuronal acetylcholine receptor subunit alpha-7	target
Methylphenobarbital	Glutamate receptor 2	target
Methylphenobarbital	Glutamate receptor ionotropic, kainate 2	target
Methylphenobarbital	Nuclear receptor subfamily 1 group I member 2	target
Irinotecan	DNA topoisomerase I, mitochondrial	target
Irinotecan	DNA topoisomerase 1	target
Irinotecan	Cytochrome P450 3A4	enzyme
Irinotecan	Cytochrome P450 3A5	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-1	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-9	enzyme
Irinotecan	Liver carboxylesterase 1	enzyme
Irinotecan	Cytochrome P450 3A7	enzyme
Irinotecan	Cytochrome P450 2B6	enzyme
Irinotecan	Solute carrier family 22 member 3	transporter
Irinotecan	Solute carrier organic anion transporter family member 1B1	transporter
Irinotecan	Multidrug resistance-associated protein 1	transporter
Irinotecan	ATP-binding cassette sub-family G member 2	transporter
Irinotecan	Serum albumin	carrier
Irinotecan	Cocaine esterase	enzyme
Irinotecan	Cholinesterase	enzyme
Irinotecan	P-glycoprotein 1	transporter
Irinotecan	Canalicular multispecific organic anion transporter 1	transporter
Promethazine	Dopamine D2 receptor	target
Promethazine	Histamine H1 receptor	target
Promethazine	Muscarinic acetylcholine receptor M4	target
Promethazine	Muscarinic acetylcholine receptor M1	target
Promethazine	Muscarinic acetylcholine receptor M5	target
Promethazine	Muscarinic acetylcholine receptor M2	target
Promethazine	Muscarinic acetylcholine receptor M3	target
Promethazine	Calmodulin	target
Promethazine	Cytochrome P450 2D6	enzyme
Promethazine	Cytochrome P450 2B6	enzyme
Promethazine	P-glycoprotein 1	transporter
Promethazine	Cytochrome P450 2C9	enzyme
Promethazine	Histamine H2 receptor	target
Promethazine	Alpha adrenergic receptor	target
Promethazine	P2 Purinoceptors	target
Promethazine	Voltage-gated sodium channel alpha subunit	target
Promethazine	Voltage-gated Potassium Channels	target
Promethazine	Canalicular multispecific organic anion transporter 2	transporter
Promethazine	Multidrug resistance-associated protein 4	transporter
Promethazine	Serum albumin	carrier
Seratrodast	Cytochrome P450 2C9	enzyme
Seratrodast	Cytochrome P450 3A4	enzyme
Seratrodast	Cytochrome P450 2C8	enzyme
Seratrodast	Cytochrome P450 2C19	enzyme
Seratrodast	Cytochrome P450 2B6	enzyme
Seratrodast	UDP-glucuronosyltransferase 1-9	enzyme
Seratrodast	Prostaglandin G/H synthase 1	enzyme
Seratrodast	Cytochrome P450 2A6	enzyme
Seratrodast	Thromboxane A2 receptor	target
Dextromethorphan	Sigma non-opioid intracellular receptor 1	target
Dextromethorphan	Neuronal acetylcholine receptor subunit alpha-2	target
Dextromethorphan	Sodium-dependent serotonin transporter	target
Dextromethorphan	Glutamate receptor ionotropic, NMDA 3A	target
Dextromethorphan	Cytochrome P450 2D6	enzyme
Dextromethorphan	Cytochrome P450 3A4	enzyme
Dextromethorphan	Cytochrome P450 3A7	enzyme
Dextromethorphan	Cytochrome P450 2C9	enzyme
Dextromethorphan	Cytochrome P450 2B6	enzyme
Dextromethorphan	Cytochrome P450 2C19	enzyme
Dextromethorphan	Membrane-associated progesterone receptor component 1	target
Dextromethorphan	Neuronal acetylcholine receptor subunit alpha-3	target
Dextromethorphan	Neuronal acetylcholine receptor subunit alpha-4	target
Dextromethorphan	Neuronal acetylcholine receptor subunit beta-4	target
Dextromethorphan	Neuronal acetylcholine receptor subunit beta-2	target
Dextromethorphan	Neuronal acetylcholine receptor subunit alpha-7	target
Dextromethorphan	Mu-type opioid receptor	target
Dextromethorphan	Delta-type opioid receptor	target
Dextromethorphan	Kappa-type opioid receptor	target
Dextromethorphan	NADPH oxidase	target
Dextromethorphan	Sodium-dependent noradrenaline transporter	target
Dextromethorphan	UDP-glucuronosyltransferase 2B4	enzyme
Dextromethorphan	UDP-glucuronosyltransferase 2B7	enzyme
Dextromethorphan	UDP-glucuronosyltransferase 2B15	enzyme
Dextromethorphan	UDP-glucuronosyltransferase 2B17	enzyme
Benzphetamine	Alpha-2A adrenergic receptor	target
Benzphetamine	Alpha-1A adrenergic receptor	target
Benzphetamine	Cytochrome P450 3A4	enzyme
Benzphetamine	Cytochrome P450 2B6	enzyme
Benzphetamine	NADPH--cytochrome P450 reductase	enzyme
Benzphetamine	Synaptic vesicular amine transporter	target
Benzphetamine	Sodium-dependent dopamine transporter	target
Artemether	Cytochrome P450 3A4	enzyme
Artemether	Cytochrome P450 3A5	enzyme
Artemether	Cytochrome P450 2B6	enzyme
Artemether	Cytochrome P450 2C9	enzyme
Artemether	Cytochrome P450 2C19	enzyme
Brompheniramine	Histamine H1 receptor	target
Brompheniramine	Muscarinic acetylcholine receptor M1	target
Brompheniramine	Muscarinic acetylcholine receptor M2	target
Brompheniramine	Muscarinic acetylcholine receptor M3	target
Brompheniramine	Muscarinic acetylcholine receptor M4	target
Brompheniramine	Muscarinic acetylcholine receptor M5	target
Clobazam	Cytochrome P450 2C19	enzyme
Clobazam	Cytochrome P450 3A4	enzyme
Clobazam	Cytochrome P450 2B6	enzyme
Clobazam	Cytochrome P450 2C18	enzyme
Clobazam	P-glycoprotein 1	transporter
Clobazam	GABA(A) Receptor	target
Clobazam	Cytochrome P450 2D6	enzyme
Clobazam	GABA(A) Receptor Benzodiazepine Binding Site	target
Clobazam	Serum albumin	carrier
Clobazam	Alpha-1-acid glycoprotein 1	carrier
Clobazam	Cytochrome P450 2C9	enzyme
Clobazam	UDP-glucuronosyltransferase 1-4	enzyme
Clobazam	UDP-glucuronosyltransferase 1-6	enzyme
Clobazam	UDP-glucuronosyltransferase 2B4	enzyme
Clobazam	UDP-glucuronosyltransferase 1-1	enzyme
Clobazam	Cytochrome P450 1A2	enzyme
Clobazam	Cytochrome P450 2C8	enzyme
Clobazam	Cytochrome P450 3A5	enzyme
Clobazam	Cytochrome P450 3A7	enzyme
Clotiazepam	Cytochrome P450 2B6	enzyme
Clotiazepam	Cytochrome P450 2C18	enzyme
Clotiazepam	Cytochrome P450 2C19	enzyme
Clotiazepam	Cytochrome P450 3A4	enzyme
Clotiazepam	GABA(A) Receptor	target
Clotiazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Epinastine	Histamine H1 receptor	target
Epinastine	Histamine H2 receptor	target
Epinastine	Alpha-1A adrenergic receptor	target
Epinastine	Alpha-2A adrenergic receptor	target
Epinastine	5-hydroxytryptamine receptor 2A	target
Epinastine	5-hydroxytryptamine receptor 7	target
Epinastine	P-glycoprotein 1	transporter
Epinastine	Cytochrome P450 2B6	enzyme
Epinastine	Cytochrome P450 2D6	enzyme
Epinastine	Cytochrome P450 3A4	enzyme
Ethylmorphine	Cytochrome P450 2D6	enzyme
Ethylmorphine	NADPH--cytochrome P450 reductase	enzyme
Ethylmorphine	Mu-type opioid receptor	target
Ethylmorphine	Cytochrome P450 2B6	enzyme
Ethylmorphine	Cytochrome P450 3A4	enzyme
Isoflurane	Calcium-transporting ATPase type 2C member 1	target
Isoflurane	ATP synthase subunit delta, mitochondrial	target
Isoflurane	Gamma-aminobutyric acid receptor subunit alpha-1	target
Isoflurane	Potassium voltage-gated channel subfamily A member 1	target
Isoflurane	Glutamate receptor 1	target
Isoflurane	Glycine receptor subunit alpha-1	target
Isoflurane	Calmodulin	target
Isoflurane	Cytochrome P450 2E1	enzyme
Isoflurane	Serum albumin	carrier
Isoflurane	Cytochrome P450 2B6	enzyme
Isoflurane	NADH-ubiquinone oxidoreductase chain 1	enzyme
Isoflurane	GABA(A) Receptor	target
Isoflurane	Neuronal acetylcholine receptor subunit alpha-4	target
Isoflurane	Neuronal acetylcholine receptor subunit beta-2	target
Ketobemidone	Prostaglandin G/H synthase 1	enzyme
Ketobemidone	Cytochrome P450 2C9	enzyme
Ketobemidone	Cytochrome P450 3A4	enzyme
Ketobemidone	UDP-glucuronosyltransferase 1-9	enzyme
Ketobemidone	Cytochrome P450 2B6	enzyme
Ketobemidone	Cytochrome P450 2C19	enzyme
Ketobemidone	Cytochrome P450 2C8	enzyme
Ketobemidone	Mu-type opioid receptor	target
Ketobemidone	Kappa-type opioid receptor	target
Ketobemidone	Delta-type opioid receptor	target
Ketobemidone	NMDA receptor	target
Methyltestosterone	Cytochrome P450 2B6	enzyme
Methyltestosterone	Cytochrome P450 3A4	enzyme
Methyltestosterone	Androgen receptor	target
Methyltestosterone	Solute carrier organic anion transporter family member 1A2	transporter
Methyltestosterone	Solute carrier family 22 member 8	transporter
Methyltestosterone	Serum albumin	carrier
Methyltestosterone	Sex hormone-binding globulin	carrier
Methyltestosterone	Estrogen receptor alpha	target
Methyltestosterone	Cytochrome P450 19A1	enzyme
Permethrin	Cytochrome P450 2B6	enzyme
Permethrin	Sodium channel protein type 1 subunit alpha	target
Permethrin	Estrogen receptor alpha	target
Permethrin	Nuclear receptor subfamily 1 group I member 2	target
Temazepam	Cytochrome P450 3A4	enzyme
Temazepam	Cytochrome P450 2B6	enzyme
Temazepam	Cytochrome P450 2C9	enzyme
Temazepam	GABA(A) Receptor	target
Temazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Testosterone	Androgen receptor	target
Testosterone	Cytochrome P450 3A4	enzyme
Testosterone	Cytochrome P450 19A1	enzyme
Testosterone	Amine oxidase [flavin-containing] A	enzyme
Testosterone	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
Testosterone	Serum albumin	carrier
Testosterone	Sex hormone-binding globulin	carrier
Testosterone	Cytochrome P450 3A5	enzyme
Testosterone	Cytochrome P450 3A7	enzyme
Testosterone	Solute carrier family 22 member 8	transporter
Testosterone	Solute carrier family 22 member 7	transporter
Testosterone	Sodium/bile acid cotransporter	transporter
Testosterone	ATP-binding cassette sub-family G member 2	transporter
Testosterone	Cytochrome P450 1A1	enzyme
Testosterone	Cytochrome P450 1B1	enzyme
Testosterone	Cytochrome P450 2A13	enzyme
Testosterone	Cytochrome P450 2B6	enzyme
Testosterone	Cytochrome P450 2C19	enzyme
Testosterone	Cytochrome P450 2C8	enzyme
Testosterone	Cytochrome P450 2C9	enzyme
Testosterone	Cytochrome P450 3A43	enzyme
Testosterone	Estrogen receptor alpha	target
Testosterone	Mineralocorticoid receptor	target
Testosterone	Solute carrier organic anion transporter family member 1B3	transporter
Banoxantrone	DNA topoisomerase 2-alpha	target
Banoxantrone	Cytochrome P450 3A4	enzyme
Banoxantrone	Cytochrome P450 1A1	enzyme
Banoxantrone	Cytochrome P450 2B6	enzyme
Prasugrel	P2Y purinoceptor 12	target
Prasugrel	Cocaine esterase	enzyme
Prasugrel	Cytochrome P450 3A4	enzyme
Prasugrel	Cytochrome P450 2B6	enzyme
Prasugrel	Cytochrome P450 2C9	enzyme
Prasugrel	Cytochrome P450 2C19	enzyme
Prasugrel	Serum albumin	carrier
Ospemifene	Estrogen receptor alpha	target
Ospemifene	Cytochrome P450 3A4	enzyme
Ospemifene	Cytochrome P450 2C9	enzyme
Ospemifene	Cytochrome P450 2C19	enzyme
Ospemifene	Cytochrome P450 2B6	enzyme
Ospemifene	Cytochrome P450 2D6	enzyme
Romidepsin	Cytochrome P450 3A4	enzyme
Romidepsin	Cytochrome P450 3A5	enzyme
Romidepsin	P-glycoprotein 1	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B3	transporter
Romidepsin	Cytochrome P450 1A1	enzyme
Romidepsin	Cytochrome P450 2B6	enzyme
Romidepsin	Cytochrome P450 2C19	enzyme
Romidepsin	Histone deacetylase 1	target
Romidepsin	Histone deacetylase 2	target
Romidepsin	Histone deacetylase 4	target
Romidepsin	Histone deacetylase 6	target
Romidepsin	Multidrug resistance-associated protein 1	target
Romidepsin	Bile salt export pump	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B1	transporter
Romidepsin	Solute carrier family 22 member 6	transporter
Romidepsin	Solute carrier family 22 member 2	transporter
Romidepsin	Histone deacetylase	target
Velpatasvir	Cytochrome P450 2B6	enzyme
Velpatasvir	Cytochrome P450 2C8	enzyme
Velpatasvir	Cytochrome P450 3A4	enzyme
Velpatasvir	Nonstructural protein 5A	target
Velpatasvir	P-glycoprotein 1	transporter
Velpatasvir	ATP-binding cassette sub-family G member 2	transporter
Velpatasvir	Solute carrier organic anion transporter family member 1B1	transporter
Velpatasvir	Solute carrier organic anion transporter family member 1B3	transporter
Velpatasvir	Solute carrier organic anion transporter family member 2B1	transporter
Brivaracetam	Synaptic vesicle glycoprotein 2A	target
Brivaracetam	Sodium channel protein	target
Brivaracetam	Cytochrome P450 3A4	enzyme
Brivaracetam	Cytochrome P450 2C19	enzyme
Brivaracetam	Cytochrome P450 2B6	enzyme
Brivaracetam	Cytochrome P450 2C9	enzyme
Testosterone cypionate	Androgen receptor	target
Testosterone cypionate	Cytochrome P450 3A4	enzyme
Testosterone cypionate	Amine oxidase [flavin-containing] A	enzyme
Testosterone cypionate	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
Testosterone cypionate	Serum albumin	carrier
Testosterone cypionate	Sex hormone-binding globulin	carrier
Testosterone cypionate	Cytochrome P450 3A5	enzyme
Testosterone cypionate	Cytochrome P450 3A7	enzyme
Testosterone cypionate	Solute carrier organic anion transporter family member 1A2	transporter
Testosterone cypionate	Solute carrier family 22 member 8	transporter
Testosterone cypionate	Solute carrier family 22 member 7	transporter
Testosterone cypionate	P-glycoprotein 1	transporter
Testosterone cypionate	Sodium/bile acid cotransporter	transporter
Testosterone cypionate	Solute carrier family 22 member 3	transporter
Testosterone cypionate	Solute carrier family 22 member 4	transporter
Testosterone cypionate	ATP-binding cassette sub-family G member 2	transporter
Testosterone cypionate	Cytochrome P450 1A1	enzyme
Testosterone cypionate	Cytochrome P450 2A13	enzyme
Testosterone cypionate	Cytochrome P450 2B6	enzyme
Testosterone cypionate	Cytochrome P450 2C19	enzyme
Testosterone cypionate	Cytochrome P450 2C8	enzyme
Testosterone cypionate	Cytochrome P450 2C9	enzyme
Testosterone cypionate	Cytochrome P450 3A43	enzyme
Testosterone cypionate	Estrogen receptor alpha	target
Testosterone cypionate	Mineralocorticoid receptor	target
Testosterone cypionate	3-oxo-5-alpha-steroid 4-dehydrogenase	enzyme
Testosterone cypionate	Cytochrome P450 19A1	enzyme
Testosterone enanthate	Androgen receptor	target
Testosterone enanthate	Cytochrome P450 3A4	enzyme
Testosterone enanthate	Amine oxidase [flavin-containing] A	enzyme
Testosterone enanthate	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
Testosterone enanthate	Serum albumin	carrier
Testosterone enanthate	Sex hormone-binding globulin	carrier
Testosterone enanthate	Cytochrome P450 3A5	enzyme
Testosterone enanthate	Cytochrome P450 3A7	enzyme
Testosterone enanthate	Solute carrier organic anion transporter family member 1A2	transporter
Testosterone enanthate	Solute carrier family 22 member 8	transporter
Testosterone enanthate	Solute carrier family 22 member 7	transporter
Testosterone enanthate	P-glycoprotein 1	transporter
Testosterone enanthate	Sodium/bile acid cotransporter	transporter
Testosterone enanthate	Solute carrier family 22 member 3	transporter
Testosterone enanthate	Solute carrier family 22 member 4	transporter
Testosterone enanthate	ATP-binding cassette sub-family G member 2	transporter
Testosterone enanthate	Cytochrome P450 1A1	enzyme
Testosterone enanthate	Cytochrome P450 2A13	enzyme
Testosterone enanthate	Cytochrome P450 2B6	enzyme
Testosterone enanthate	Cytochrome P450 2C19	enzyme
Testosterone enanthate	Cytochrome P450 2C8	enzyme
Testosterone enanthate	Cytochrome P450 2C9	enzyme
Testosterone enanthate	Cytochrome P450 3A43	enzyme
Testosterone enanthate	Estrogen receptor alpha	target
Testosterone enanthate	Mineralocorticoid receptor	target
Testosterone enanthate	3-oxo-5-alpha-steroid 4-dehydrogenase	enzyme
Testosterone enanthate	Cytochrome P450 19A1	enzyme
Testosterone undecanoate	Androgen receptor	target
Testosterone undecanoate	Cytochrome P450 3A4	enzyme
Testosterone undecanoate	Amine oxidase [flavin-containing] A	enzyme
Testosterone undecanoate	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
Testosterone undecanoate	Serum albumin	carrier
Testosterone undecanoate	Sex hormone-binding globulin	carrier
Testosterone undecanoate	Cytochrome P450 3A5	enzyme
Testosterone undecanoate	Cytochrome P450 3A7	enzyme
Testosterone undecanoate	Solute carrier organic anion transporter family member 1A2	transporter
Testosterone undecanoate	Solute carrier family 22 member 8	transporter
Testosterone undecanoate	Solute carrier family 22 member 7	transporter
Testosterone undecanoate	P-glycoprotein 1	transporter
Testosterone undecanoate	Sodium/bile acid cotransporter	transporter
Testosterone undecanoate	Solute carrier family 22 member 4	transporter
Testosterone undecanoate	ATP-binding cassette sub-family G member 2	transporter
Testosterone undecanoate	Cytochrome P450 1A1	enzyme
Testosterone undecanoate	Cytochrome P450 1B1	enzyme
Testosterone undecanoate	Cytochrome P450 2A13	enzyme
Testosterone undecanoate	Cytochrome P450 2B6	enzyme
Testosterone undecanoate	Cytochrome P450 2C19	enzyme
Testosterone undecanoate	Cytochrome P450 2C8	enzyme
Testosterone undecanoate	Cytochrome P450 2C9	enzyme
Testosterone undecanoate	Cytochrome P450 3A43	enzyme
Testosterone undecanoate	3-oxo-5-alpha-steroid 4-dehydrogenase	enzyme
Testosterone undecanoate	Solute carrier family 22 member 2	transporter
Testosterone undecanoate	Multidrug and toxin extrusion protein 1	transporter
Testosterone undecanoate	Solute carrier organic anion transporter family member 1B3	transporter
Testosterone undecanoate	Cytochrome P450 19A1	enzyme
Artemisinin	Cytochrome P450 2B6	enzyme
Esketamine	NMDA receptor	target
Esketamine	Cytochrome P450 2B6	enzyme
Esketamine	Cytochrome P450 3A4	enzyme
Esketamine	Cytochrome P450 2C19	enzyme
Esketamine	Cytochrome P450 2C9	enzyme
Esketamine	Glutamate receptor ionotropic, NMDA 2B	target
Esketamine	Elongation factor 2	target
Esketamine	Brain-derived neurotrophic factor	target
Esketamine	BDNF/NT-3 growth factors receptor	target
Hydrocodone	Mu-type opioid receptor	target
Hydrocodone	Delta-type opioid receptor	target
Hydrocodone	Cytochrome P450 3A4	enzyme
Hydrocodone	Cytochrome P450 2D6	enzyme
Hydrocodone	Cytochrome P450 2B6	enzyme
Hydrocodone	Cytochrome P450 2C19	enzyme
Hydrocodone	Sigma non-opioid intracellular receptor 1	target
Amlodipine	Carbonic anhydrase 1	target
Amlodipine	Cytochrome P450 3A4	enzyme
Amlodipine	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Amlodipine	Cytochrome P450 1A1	enzyme
Amlodipine	Cytochrome P450 2B6	enzyme
Amlodipine	Voltage-dependent N-type calcium channel subunit alpha-1B	target
Amlodipine	Voltage-dependent L-type calcium channel subunit beta-1	target
Amlodipine	Voltage-dependent calcium channel subunit alpha-2/delta-3	target
Amlodipine	Cytochrome P450 3A5	enzyme
Amlodipine	P-glycoprotein 1	transporter
Amlodipine	Cytochrome P450 2C8	enzyme
Amlodipine	Cytochrome P450 2D6	enzyme
Amlodipine	Sphingomyelin phosphodiesterase	target
Amlodipine	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Amlodipine	Voltage-dependent N-type calcium channel	target
Amlodipine	Cytochrome P450 2C19	enzyme
Amlodipine	Cytochrome P450 2C9	enzyme
Diazepam	Cytochrome P450 3A4	enzyme
Diazepam	Serum albumin	carrier
Diazepam	Cytochrome P450 2C9	enzyme
Diazepam	Cytochrome P450 2C19	enzyme
Diazepam	Cytochrome P450 3A5	enzyme
Diazepam	Cytochrome P450 3A7	enzyme
Diazepam	P-glycoprotein 1	transporter
Diazepam	Cytochrome P450 2B6	enzyme
Diazepam	Prostaglandin G/H synthase 1	enzyme
Diazepam	Cytochrome P450 2C18	enzyme
Diazepam	Cytochrome P450 2C8	enzyme
Diazepam	GABA(A) Receptor	target
Diazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
Dexloxiglumide	Cholecystokinin receptor type A	target
Dexloxiglumide	Cytochrome P450 3A4	enzyme
Dexloxiglumide	Cytochrome P450 2C9	enzyme
Dexloxiglumide	Cytochrome P450 3A5	enzyme
Dexloxiglumide	Cytochrome P450 2B6	enzyme
Dexloxiglumide	Cytochrome P450 2E1	enzyme
Metoprolol	Beta-1 adrenergic receptor	target
Metoprolol	Cytochrome P450 2D6	enzyme
Metoprolol	Beta-2 adrenergic receptor	target
Metoprolol	Solute carrier family 22 member 2	transporter
Metoprolol	Serum albumin	carrier
Metoprolol	Cytochrome P450 3A4	enzyme
Metoprolol	Beta adrenergic receptor	target
Venlafaxine	Sodium-dependent serotonin transporter	target
Venlafaxine	Sodium-dependent noradrenaline transporter	target
Venlafaxine	Cytochrome P450 2D6	enzyme
Venlafaxine	Cytochrome P450 3A4	enzyme
Venlafaxine	Sodium-dependent dopamine transporter	target
Venlafaxine	P-glycoprotein 1	transporter
Venlafaxine	ATP-binding cassette sub-family G member 2	transporter
Venlafaxine	Cytochrome P450 2C9	enzyme
Venlafaxine	Cytochrome P450 2C19	enzyme
Atomoxetine	Sodium-dependent noradrenaline transporter	target
Atomoxetine	Cytochrome P450 2D6	enzyme
Atomoxetine	Sodium-dependent serotonin transporter	target
Atomoxetine	Cytochrome P450 2C19	enzyme
Atomoxetine	NMDA receptor	target
Atomoxetine	Serum albumin	carrier
Atomoxetine	alpha1-acid glycoprotein	carrier
Atomoxetine	High affinity immunoglobulin gamma Fc receptor I	carrier
Atomoxetine	G protein-activated inward rectifier potassium channel 1	target
Atomoxetine	Kappa-type opioid receptor	target
Codeine	Mu-type opioid receptor	target
Codeine	Delta-type opioid receptor	target
Codeine	Kappa-type opioid receptor	target
Codeine	Cytochrome P450 2D6	enzyme
Codeine	Cytochrome P450 3A4	enzyme
Codeine	Solute carrier family 22 member 1	transporter
Codeine	UDP-glucuronosyltransferase 2B7	enzyme
Codeine	UDP-glucuronosyltransferase 2B4	enzyme
Timolol	Beta-1 adrenergic receptor	target
Timolol	Beta-2 adrenergic receptor	target
Timolol	Cytochrome P450 2D6	enzyme
Timolol	P-glycoprotein 1	transporter
Timolol	Cytochrome P450 2C19	enzyme
Timolol	Lysozyme	target
Oxycodone	Mu-type opioid receptor	target
Oxycodone	Kappa-type opioid receptor	target
Oxycodone	Delta-type opioid receptor	target
Oxycodone	Cytochrome P450 2D6	enzyme
Oxycodone	Cytochrome P450 3A4	enzyme
Oxycodone	Cytochrome P450 3A5	enzyme
Oxycodone	Serum albumin	carrier
Oxycodone	alpha1-acid glycoprotein	carrier
Thioridazine	Alpha-1A adrenergic receptor	target
Thioridazine	Dopamine D2 receptor	target
Thioridazine	5-hydroxytryptamine receptor 2A	target
Thioridazine	Dopamine D1 receptor	target
Thioridazine	Cytochrome P450 2C19	enzyme
Thioridazine	Cytochrome P450 2D6	enzyme
Thioridazine	Alpha-1B adrenergic receptor	target
Thioridazine	Potassium voltage-gated channel subfamily H member 2	target
Thioridazine	Cytochrome P450 2E1	enzyme
Risperidone	Cytochrome P450 2D6	enzyme
Risperidone	Cytochrome P450 3A4	enzyme
Risperidone	P-glycoprotein 1	transporter
Risperidone	Serum albumin	carrier
Risperidone	Alpha-1-acid glycoprotein 1	carrier
Risperidone	5-hydroxytryptamine receptor 2A	target
Risperidone	Dopamine D2 receptor	target
Risperidone	Alpha-1B adrenergic receptor	target
Risperidone	Alpha-2B adrenergic receptor	target
Risperidone	Alpha-1A adrenergic receptor	target
Risperidone	Alpha-2C adrenergic receptor	target
Risperidone	Histamine H1 receptor	target
Risperidone	5-hydroxytryptamine receptor 2C	target
Risperidone	5-hydroxytryptamine receptor 1D	target
Risperidone	5-hydroxytryptamine receptor 1A	target
Risperidone	5-hydroxytryptamine receptor 7	target
Risperidone	D(2L) dopamine receptor	target
Risperidone	Dopamine D1 receptor	target
Flecainide	Sodium channel protein type 5 subunit alpha	target
Flecainide	Cytochrome P450 2D6	enzyme
Flecainide	Sodium channel protein type 4 subunit alpha	target
Flecainide	Cytochrome P450 2C9	enzyme
Flecainide	Potassium voltage-gated channel subfamily H member 2	target
Flecainide	alpha1-acid glycoprotein	carrier
Flecainide	Serum albumin	carrier
Flecainide	Cytochrome P450 1A2	enzyme
Flecainide	P-glycoprotein 1	transporter
Flecainide	Multidrug and toxin extrusion protein 1	transporter
Flecainide	Ryanodine receptor 2	target
Aripiprazole	Dopamine D2 receptor	target
Aripiprazole	5-hydroxytryptamine receptor 1A	target
Aripiprazole	5-hydroxytryptamine receptor 2A	target
Aripiprazole	Cytochrome P450 3A4	enzyme
Aripiprazole	Cytochrome P450 2D6	enzyme
Aripiprazole	5-hydroxytryptamine receptor 1B	target
Aripiprazole	5-hydroxytryptamine receptor 1D	target
Aripiprazole	5-hydroxytryptamine receptor 1E	target
Aripiprazole	Dopamine D1 receptor	target
Aripiprazole	Dopamine D5 receptor	target
Aripiprazole	Dopamine D3 receptor	target
Aripiprazole	Dopamine D4 receptor	target
Aripiprazole	5-hydroxytryptamine receptor 2C	target
Aripiprazole	5-hydroxytryptamine receptor 3A	target
Aripiprazole	5-hydroxytryptamine receptor 6	target
Aripiprazole	5-hydroxytryptamine receptor 7	target
Aripiprazole	Histamine H1 receptor	target
Aripiprazole	Alpha-1A adrenergic receptor	target
Aripiprazole	Alpha-1B adrenergic receptor	target
Aripiprazole	Alpha-2A adrenergic receptor	target
Aripiprazole	Alpha-2B adrenergic receptor	target
Aripiprazole	Alpha-2C adrenergic receptor	target
Aripiprazole	Cytochrome P450 3A5	enzyme
Aripiprazole	Cytochrome P450 3A7	enzyme
Aripiprazole	Serum albumin	carrier
Aripiprazole	5-hydroxytryptamine receptor 2B	target
Aripiprazole	5-hydroxytryptamine receptor 5A	target
Aripiprazole	Beta-1 adrenergic receptor	target
Aripiprazole	Beta-2 adrenergic receptor	target
Aripiprazole	Histamine H2 receptor	target
Aripiprazole	Histamine H3 receptor	target
Aripiprazole	Histamine H4 receptor	target
Aripiprazole	Muscarinic acetylcholine receptor M1	target
Aripiprazole	Muscarinic acetylcholine receptor M2	target
Aripiprazole	Muscarinic acetylcholine receptor M3	target
Aripiprazole	Muscarinic acetylcholine receptor M4	target
Aripiprazole	Muscarinic acetylcholine receptor M5	target
Aripiprazole	Kappa-type opioid receptor	target
Aripiprazole	Mu-type opioid receptor	target
Aripiprazole	Delta-type opioid receptor	target
Aripiprazole	Glutamate (NMDA) receptor	target
Aripiprazole	Sodium-dependent dopamine transporter	target
Aripiprazole	Sodium-dependent serotonin transporter	target
Aripiprazole	P-glycoprotein 1	transporter
Aripiprazole	ATP-binding cassette sub-family G member 2	transporter
Tafenoquine	Cytochrome P450 2D6	enzyme
Tafenoquine	Ferredoxin--NADP reductase, apicoplast	enzyme
Tafenoquine	Solute carrier family 22 member 2	transporter
Tafenoquine	Multidrug and toxin extrusion protein 1	transporter
Tafenoquine	Multidrug and toxin extrusion protein 2	transporter
Progesterone	Progesterone receptor	target
Progesterone	Estrogen receptor alpha	target
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Progesterone	Cytochrome P450 2C19	enzyme
Progesterone	Cytochrome P450 2C9	enzyme
Progesterone	Cytochrome P450 3A4	enzyme
Progesterone	Cytochrome P450 3A5	enzyme
Progesterone	Cytochrome P450 3A7	enzyme
Progesterone	P-glycoprotein 1	transporter
Progesterone	Solute carrier family 22 member 2	transporter
Progesterone	Solute carrier family 22 member 1	transporter
Progesterone	Solute carrier family 22 member 3	transporter
Progesterone	Bile salt export pump	transporter
Progesterone	Multidrug resistance-associated protein 1	transporter
Progesterone	Sodium/bile acid cotransporter	transporter
Progesterone	Steroid 17-alpha-hydroxylase/17,20 lyase	enzyme
Progesterone	Cytochrome P450 1A1	enzyme
Progesterone	Cytochrome P450 1B1	enzyme
Progesterone	Cytochrome P450 2A6	enzyme
Progesterone	Cytochrome P450 2D6	enzyme
Progesterone	Mineralocorticoid receptor	target
Progesterone	Kappa-type opioid receptor	target
Progesterone	Alpha-1-acid glycoprotein 1	target
Progesterone	Glucocorticoid receptor	target
Progesterone	Androgen receptor	target
Progesterone	Sex hormone-binding globulin	target
Progesterone	Solute carrier organic anion transporter family member 1B1	transporter
Progesterone	ATP-binding cassette sub-family G member 2	transporter
Progesterone	Estrogen receptor beta	target
Progesterone	Solute carrier organic anion transporter family member 1B3	transporter
Elagolix	Gonadotropin-releasing hormone receptor	target
Elagolix	Cytochrome P450 3A Subfamily	enzyme
Elagolix	Cytochrome P450 2D6	enzyme
Elagolix	Cytochrome P450 2C8	enzyme
Elagolix	P-glycoprotein 1	transporter
Elagolix	Solute carrier organic anion transporter family member 1B1	transporter
Acebutolol	Beta-1 adrenergic receptor	target
Acebutolol	Cytochrome P450 2D6	enzyme
Acebutolol	Beta-2 adrenergic receptor	target
Acebutolol	P-glycoprotein 1	transporter
Alprenolol	Beta-1 adrenergic receptor	target
Alprenolol	Beta-2 adrenergic receptor	target
Alprenolol	5-hydroxytryptamine receptor 1A	target
Alprenolol	Cytochrome P450 2D6	enzyme
Alprenolol	Beta-3 adrenergic receptor	target
Anisodamine	Cytochrome P450 2D6	enzyme
Arotinolol	Beta-1 adrenergic receptor	target
Arotinolol	Beta-2 adrenergic receptor	target
Arotinolol	Alpha-1 adrenergic receptors	target
Arotinolol	Serum albumin	carrier
Arotinolol	Alpha-1-acid glycoprotein 1	carrier
Arotinolol	Cytochrome P450 2D6	enzyme
Atenolol	Beta-1 adrenergic receptor	target
Atenolol	Beta-2 adrenergic receptor	target
Atenolol	Cytochrome P450 2D6	enzyme
Atenolol	Bile salt export pump	transporter
Atenolol	Serum albumin	carrier
Befunolol	Beta-1 adrenergic receptor	target
Befunolol	Beta-2 adrenergic receptor	target
Befunolol	Cytochrome P450 2D6	enzyme
Bevantolol	Beta-1 adrenergic receptor	target
Bevantolol	Beta-2 adrenergic receptor	target
Bevantolol	Alpha-1A adrenergic receptor	target
Bevantolol	Cytochrome P450 2D6	enzyme
Bopindolol	Beta-1 adrenergic receptor	target
Bopindolol	Beta-2 adrenergic receptor	target
Bopindolol	5-hydroxytryptamine receptor 1A	target
Bopindolol	5-hydroxytryptamine receptor 1B	target
Bopindolol	Beta-3 adrenergic receptor	target
Bopindolol	Cytochrome P450 2D6	enzyme
Bucindolol	Cytochrome P450 2D6	enzyme
Bufuralol	Cytochrome P450 2D6	enzyme
Bufuralol	Beta adrenergic receptor	target
Bupranolol	Beta-1 adrenergic receptor	target
Bupranolol	Beta-2 adrenergic receptor	target
Bupranolol	Beta-3 adrenergic receptor	target
Bupranolol	Cytochrome P450 2D6	enzyme
Carteolol	Beta-2 adrenergic receptor	target
Carteolol	Beta-1 adrenergic receptor	target
Carteolol	Cytochrome P450 2D6	enzyme
Celiprolol	Beta-1 adrenergic receptor	target
Celiprolol	Beta-2 adrenergic receptor	target
Celiprolol	Beta-3 adrenergic receptor	target
Celiprolol	Alpha-2A adrenergic receptor	target
Celiprolol	Alpha-2B adrenergic receptor	target
Celiprolol	Alpha-2C adrenergic receptor	target
Celiprolol	Cytochrome P450 2D6	enzyme
Cloranolol	Cytochrome P450 2D6	enzyme
Epanolol	Cytochrome P450 2D6	enzyme
Esatenolol	Cytochrome P450 2D6	enzyme
Esmolol	Beta-1 adrenergic receptor	target
Esmolol	Cytochrome P450 2D6	enzyme
Indenolol	Cytochrome P450 2D6	enzyme
Landiolol	Cytochrome P450 2D6	enzyme
Levobetaxolol	Beta-1 adrenergic receptor	target
Levobetaxolol	Cytochrome P450 2D6	enzyme
Levobunolol	Beta-1 adrenergic receptor	target
Levobunolol	Beta-2 adrenergic receptor	target
Levobunolol	Cytochrome P450 2D6	enzyme
Mepindolol	Cytochrome P450 2D6	enzyme
Metipranolol	Beta-1 adrenergic receptor	target
Metipranolol	Beta-2 adrenergic receptor	target
Metipranolol	Cytochrome P450 2D6	enzyme
Nadolol	Beta-1 adrenergic receptor	target
Nadolol	Beta-2 adrenergic receptor	target
Nadolol	P-glycoprotein 1	transporter
Nadolol	POU domain, class 2, transcription factor 1	transporter
Nadolol	POU domain, class 2, transcription factor 2	transporter
Nadolol	Multidrug and toxin extrusion protein 1	transporter
Nadolol	Multidrug and toxin extrusion protein 2	transporter
Nadolol	alpha1-acid glycoprotein	carrier
Nebivolol	Beta-1 adrenergic receptor	target
Nebivolol	Cytochrome P450 2D6	enzyme
Nebivolol	Beta-2 adrenergic receptor	target
Nebivolol	Cytochrome P450 3A4	enzyme
Nebivolol	Serum albumin	carrier
Nebivolol	Beta-3 adrenergic receptor	target
Nebivolol	Cytochrome P450 2C19	enzyme
Oxprenolol	Beta-1 adrenergic receptor	target
Oxprenolol	Beta-2 adrenergic receptor	target
Oxprenolol	Solute carrier family 22 member 2	transporter
Oxprenolol	Cytochrome P450 2D6	enzyme
Oxprenolol	Beta-3 adrenergic receptor	target
Penbutolol	Alpha-1-acid glycoprotein 1	carrier
Penbutolol	Beta-1 adrenergic receptor	target
Penbutolol	Beta-2 adrenergic receptor	target
Penbutolol	5-hydroxytryptamine receptor 1A	target
Penbutolol	5-hydroxytryptamine receptor 1B	target
Penbutolol	Cytochrome P450 2D6	enzyme
Pindolol	Beta-1 adrenergic receptor	target
Pindolol	Beta-2 adrenergic receptor	target
Pindolol	5-hydroxytryptamine receptor 1A	target
Pindolol	5-hydroxytryptamine receptor 1B	target
Pindolol	Cytochrome P450 2D6	enzyme
Pindolol	Beta-3 adrenergic receptor	target
Pindolol	UDP-glucuronosyltransferases (UGTs)	enzyme
Pindolol	Sulfotransferase	enzyme
Pindolol	Solute carrier family 22 member 2	transporter
Pindolol	alpha1-acid glycoprotein	carrier
Practolol	Beta-1 adrenergic receptor	target
Practolol	Cytochrome P450 2D6	enzyme
Sotalol	Potassium voltage-gated channel subfamily H member 2	target
Sotalol	Beta-1 adrenergic receptor	target
Sotalol	Beta-2 adrenergic receptor	target
Sotalol	Cytochrome P450 2D6	enzyme
Talinolol	Cytochrome P450 2D6	enzyme
Talinolol	P-glycoprotein 1	transporter
Talinolol	Canalicular multispecific organic anion transporter 1	transporter
Tertatolol	Cytochrome P450 2D6	enzyme
Paliperidone	Dopamine D2 receptor	target
Paliperidone	5-hydroxytryptamine receptor 2A	target
Paliperidone	Histamine H1 receptor	target
Paliperidone	Alpha-1A adrenergic receptor	target
Paliperidone	Alpha-1B adrenergic receptor	target
Paliperidone	Dopamine D3 receptor	target
Paliperidone	Dopamine D4 receptor	target
Paliperidone	Dopamine D1 receptor	target
Paliperidone	Alpha-2A adrenergic receptor	target
Paliperidone	Alpha-2B adrenergic receptor	target
Paliperidone	Alpha-2C adrenergic receptor	target
Paliperidone	5-hydroxytryptamine receptor 1A	target
Paliperidone	5-hydroxytryptamine receptor 1D	target
Paliperidone	5-hydroxytryptamine receptor 2C	target
Paliperidone	5-hydroxytryptamine receptor 7	target
Paliperidone	Cytochrome P450 3A4	enzyme
Paliperidone	Cytochrome P450 2D6	enzyme
Paliperidone	Cytochrome P450 3A5	enzyme
Paliperidone	P-glycoprotein 1	transporter
Dapoxetine	5-hydroxytryptamine receptor 1A	target
Dapoxetine	5-hydroxytryptamine receptor 1B	target
Dapoxetine	5-hydroxytryptamine receptor 2C	target
Dapoxetine	Cytochrome P450 3A4	enzyme
Dapoxetine	Cytochrome P450 2D6	enzyme
Citalopram	Sodium-dependent serotonin transporter	target
Citalopram	Cytochrome P450 2C19	enzyme
Citalopram	Cytochrome P450 2D6	enzyme
Citalopram	Cytochrome P450 3A4	enzyme
Citalopram	P-glycoprotein 1	transporter
Citalopram	Cytochrome P450 1A2	enzyme
Citalopram	Histamine H1 receptor	target
Citalopram	Amine oxidase [flavin-containing] A	enzyme
Citalopram	Amine oxidase [flavin-containing] B	enzyme
Citalopram	Aldehyde oxidase	enzyme
Escitalopram	Sodium-dependent serotonin transporter	target
Escitalopram	Cytochrome P450 3A4	enzyme
Escitalopram	Cytochrome P450 2D6	enzyme
Escitalopram	Sodium-dependent dopamine transporter	target
Escitalopram	Sodium-dependent noradrenaline transporter	target
Escitalopram	Muscarinic acetylcholine receptor M1	target
Escitalopram	Histamine H1 receptor	target
Escitalopram	Cytochrome P450 2C19	enzyme
Escitalopram	P-glycoprotein 1	transporter
Escitalopram	5-hydroxytryptamine receptor 1A	target
Escitalopram	5-hydroxytryptamine receptor 2A	target
Escitalopram	5-hydroxytryptamine receptor 2C	target
Escitalopram	Alpha-1 adrenergic receptors	target
Escitalopram	Alpha-2 adrenergic receptors	target
Escitalopram	Dopamine D2 receptor	target
Escitalopram	Amine oxidase [flavin-containing] A	enzyme
Escitalopram	Amine oxidase [flavin-containing] B	enzyme
Escitalopram	Aldehyde oxidase	enzyme
Levomilnacipran	Cytochrome P450 3A4	enzyme
Levomilnacipran	Cytochrome P450 2C8	enzyme
Levomilnacipran	Cytochrome P450 2C19	enzyme
Levomilnacipran	Cytochrome P450 2D6	enzyme
Levomilnacipran	Cytochrome P450 2J2	enzyme
Levomilnacipran	Sodium-dependent serotonin transporter	target
Levomilnacipran	Sodium-dependent noradrenaline transporter	target
Levomilnacipran	P-glycoprotein 1	transporter
Nefazodone	5-hydroxytryptamine receptor 2A	target
Nefazodone	Sodium-dependent serotonin transporter	target
Nefazodone	Sodium-dependent noradrenaline transporter	target
Nefazodone	Alpha-1A adrenergic receptor	target
Nefazodone	Alpha-1B adrenergic receptor	target
Nefazodone	Cytochrome P450 3A4	enzyme
Nefazodone	Cytochrome P450 2D6	enzyme
Nefazodone	Sodium-dependent dopamine transporter	target
Nefazodone	Alpha-2A adrenergic receptor	target
Nefazodone	5-hydroxytryptamine receptor 1A	target
Nefazodone	CYP2B protein	enzyme
Nefazodone	P-glycoprotein 1	transporter
Nefazodone	5-hydroxytryptamine receptor 2C	target
Nefazodone	Potassium voltage-gated channel subfamily H member 2	target
Nefazodone	Cytochrome P450 3A Subfamily	enzyme
Nefazodone	Solute carrier organic anion transporter family member 1B3	transporter
Nefazodone	Solute carrier organic anion transporter family member 2B1	transporter
Nefazodone	Bile salt export pump	transporter
Trazodone	5-hydroxytryptamine receptor 2A	target
Trazodone	Sodium-dependent serotonin transporter	target
Trazodone	Alpha-1A adrenergic receptor	target
Trazodone	Alpha-2A adrenergic receptor	target
Trazodone	Histamine H1 receptor	target
Trazodone	5-hydroxytryptamine receptor 1A	target
Trazodone	Cytochrome P450 2D6	enzyme
Trazodone	Cytochrome P450 3A4	enzyme
Trazodone	5-hydroxytryptamine receptor 2C	target
Trazodone	Cytochrome P450 3A5	enzyme
Trazodone	Cytochrome P450 3A7	enzyme
Trazodone	P-glycoprotein 1	transporter
Trazodone	5-hydroxytryptamine receptor 1C	target
Fusidic acid	Chloramphenicol acetyltransferase 3	target
Fusidic acid	Chloramphenicol acetyltransferase	target
Fusidic acid	Bile salt export pump	transporter
Fusidic acid	Canalicular multispecific organic anion transporter 1	transporter
Fusidic acid	Elongation factor G	target
Fusidic acid	Cytochrome P450 2D6	enzyme
Fusidic acid	Cytochrome P450 3A4	enzyme
Fusidic acid	UDP-glucuronosyltransferase 1-1	enzyme
Fusidic acid	ATP-binding cassette sub-family G member 2	transporter
Fusidic acid	Solute carrier organic anion transporter family member 1B1	transporter
Galantamine	Acetylcholinesterase	target
Galantamine	Cytochrome P450 3A4	enzyme
Galantamine	Cytochrome P450 2D6	enzyme
Galantamine	Cholinesterase	target
Galantamine	P-glycoprotein 1	transporter
Galantamine	Neuronal acetylcholine receptor subunit alpha-7	target
Galantamine	Muscle nicotinic acetylcholine receptor	target
Dasabuvir	Nonstructural protein 5B (NS5B)	target
Dasabuvir	Cytochrome P450 2C8	enzyme
Dasabuvir	Cytochrome P450 3A4	enzyme
Dasabuvir	Cytochrome P450 2D6	enzyme
Dasabuvir	UDP-glucuronosyltransferase 1-1	enzyme
Dasabuvir	ATP-binding cassette sub-family G member 2	transporter
Dasabuvir	ATP-binding cassette sub-family B member 5	transporter
Dasabuvir	P-glycoprotein 1	transporter
Buprenorphine	Kappa-type opioid receptor	target
Buprenorphine	Mu-type opioid receptor	target
Buprenorphine	Cytochrome P450 3A4	enzyme
Buprenorphine	Cytochrome P450 2D6	enzyme
Buprenorphine	P-glycoprotein 1	transporter
Buprenorphine	ATP-binding cassette sub-family G member 2	transporter
Buprenorphine	Cytochrome P450 2C9	enzyme
Buprenorphine	Cytochrome P450 3A5	enzyme
Buprenorphine	Cytochrome P450 2C8	enzyme
Buprenorphine	Cytochrome P450 3A7	enzyme
Buprenorphine	Delta-type opioid receptor	target
Buprenorphine	Cytochrome P450 2C18	enzyme
Buprenorphine	Cytochrome P450 2C19	enzyme
Buprenorphine	Nociceptin receptor	target
Buspirone	5-hydroxytryptamine receptor 1A	target
Buspirone	Dopamine D2 receptor	target
Buspirone	Cytochrome P450 3A4	enzyme
Buspirone	Cytochrome P450 3A5	enzyme
Buspirone	Cytochrome P450 3A7	enzyme
Buspirone	P-glycoprotein 1	transporter
Buspirone	Cytochrome P450 2D6	enzyme
Buspirone	Serum albumin	carrier
Buspirone	Alpha-1-acid glycoprotein 1	carrier
Buspirone	Dopamine D3 receptor	target
Buspirone	Dopamine D4 receptor	target
Buspirone	Alpha-1 adrenergic receptors	target
Bepridil	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	target
Bepridil	Sodium/potassium-transporting ATPase subunit alpha-1	target
Bepridil	Potassium voltage-gated channel subfamily KQT member 1	target
Bepridil	Troponin C, slow skeletal and cardiac muscles	target
Bepridil	Calmodulin	target
Bepridil	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Bepridil	Voltage-dependent calcium channel subunit alpha-2/delta-2	target
Bepridil	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	target
Bepridil	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	target
Bepridil	P-glycoprotein 1	transporter
Bepridil	Cytochrome P450 2D6	enzyme
Bepridil	Potassium voltage-gated channel subfamily H member 2	target
Bepridil	Cytochrome P450 3A4	enzyme
Fluvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Fluvastatin	Cytochrome P450 2C9	enzyme
Fluvastatin	Cytochrome P450 3A4	enzyme
Fluvastatin	Cytochrome P450 2C8	enzyme
Fluvastatin	Cytochrome P450 2D6	enzyme
Fluvastatin	Cytochrome P450 2C19	enzyme
Fluvastatin	Cytochrome P450 1A1	enzyme
Fluvastatin	Solute carrier organic anion transporter family member 1B1	transporter
Fluvastatin	Solute carrier organic anion transporter family member 1B3	transporter
Fluvastatin	Solute carrier organic anion transporter family member 2B1	transporter
Fluvastatin	Solute carrier family 15 member 1	transporter
Fluvastatin	Cytochrome P450 3A5	enzyme
Fluvastatin	UDP-glucuronosyltransferase 1-1	enzyme
Fluvastatin	UDP-glucuronosyltransferase 1-3	enzyme
Fluvastatin	UDP-glucuronosyltransferase 2B7	enzyme
Fluvastatin	Canalicular multispecific organic anion transporter 1	transporter
Fluvastatin	Cytochrome P450 2B6	enzyme
Fluvastatin	Histone deacetylase 2	target
Aripiprazole lauroxil	Dopamine D2 receptor	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 1A	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 2A	target
Aripiprazole lauroxil	Cytochrome P450 3A4	enzyme
Aripiprazole lauroxil	Cytochrome P450 2D6	enzyme
Aripiprazole lauroxil	5-hydroxytryptamine receptor 1B	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 1D	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 1E	target
Aripiprazole lauroxil	Dopamine D1 receptor	target
Aripiprazole lauroxil	Dopamine D5 receptor	target
Aripiprazole lauroxil	Dopamine D3 receptor	target
Aripiprazole lauroxil	Dopamine D4 receptor	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 2C	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 3A	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 6	target
Aripiprazole lauroxil	5-hydroxytryptamine receptor 7	target
Aripiprazole lauroxil	Histamine H1 receptor	target
Aripiprazole lauroxil	Alpha-1A adrenergic receptor	target
Aripiprazole lauroxil	Alpha-1B adrenergic receptor	target
Aripiprazole lauroxil	Alpha-2A adrenergic receptor	target
Aripiprazole lauroxil	Alpha-2B adrenergic receptor	target
Aripiprazole lauroxil	Alpha-2C adrenergic receptor	target
Aripiprazole lauroxil	Muscarinic acetylcholine receptor M1	target
Aripiprazole lauroxil	Muscarinic acetylcholine receptor M2	target
Aripiprazole lauroxil	Muscarinic acetylcholine receptor M3	target
Aripiprazole lauroxil	Muscarinic acetylcholine receptor M4	target
Aripiprazole lauroxil	Muscarinic acetylcholine receptor M5	target
Aripiprazole lauroxil	Cytochrome P450 3A5	enzyme
Aripiprazole lauroxil	Cytochrome P450 3A7	enzyme
Aripiprazole lauroxil	Serum albumin	carrier
Zuclopenthixol	Dopamine D1 receptor	target
Zuclopenthixol	Dopamine D5 receptor	target
Zuclopenthixol	Dopamine D2 receptor	target
Zuclopenthixol	Cytochrome P450 2D6	enzyme
Zuclopenthixol	Alpha-1A adrenergic receptor	target
Zuclopenthixol	Alpha-2A adrenergic receptor	target
Zuclopenthixol	5-hydroxytryptamine receptor 2A	target
Zuclopenthixol	Histamine H1 receptor	target
Zuclopenthixol	Cytochrome P450 3A4	enzyme
Fesoterodine	Muscarinic acetylcholine receptor M1	target
Fesoterodine	Muscarinic acetylcholine receptor M3	target
Fesoterodine	Cytochrome P450 3A4	enzyme
Fesoterodine	Muscarinic acetylcholine receptor M2	target
Fesoterodine	Muscarinic acetylcholine receptor M4	target
Fesoterodine	Muscarinic acetylcholine receptor M5	target
Fesoterodine	Cytochrome P450 2D6	enzyme
Fesoterodine	P-glycoprotein 1	transporter
Pitolisant	Histamine H3 receptor	target
Pitolisant	Cytochrome P450 3A4	enzyme
Pitolisant	Cytochrome P450 2D6	enzyme
Pitolisant	Cytochrome P450 1A2	enzyme
Pitolisant	Cytochrome P450 2B6	enzyme
Pitolisant	Solute carrier family 22 member 1	transporter
Pitolisant	Potassium voltage-gated channel subfamily H member 2	target
Pitolisant	Serum albumin	carrier
Pitolisant	Alpha-1-acid glycoprotein 1	carrier
Brexpiprazole	Cytochrome P450 2D6	enzyme
Brexpiprazole	Cytochrome P450 3A4	enzyme
Brexpiprazole	5-hydroxytryptamine receptor 1A	target
Brexpiprazole	Dopamine D2 receptor	target
Brexpiprazole	5-hydroxytryptamine receptor 2A	target
Brexpiprazole	Alpha-2C adrenergic receptor	target
Brexpiprazole	Alpha-1B adrenergic receptor	target
Brexpiprazole	Multidrug and toxin extrusion protein 2	transporter
Brexpiprazole	Serum albumin	carrier
Brexpiprazole	Alpha-1-acid glycoprotein 1	carrier
Brexpiprazole	Dopamine D3 receptor	target
Brexpiprazole	5-hydroxytryptamine receptor 2B	target
Brexpiprazole	5-hydroxytryptamine receptor 7	target
Brexpiprazole	Alpha-1A adrenergic receptor	target
Brexpiprazole	Alpha-1D adrenergic receptor	target
Brexpiprazole	Histamine H1 receptor	target
Brexpiprazole	Muscarinic acetylcholine receptor M1	target
Eliglustat	Ceramide glucosyltransferase	target
Eliglustat	Cytochrome P450 2D6	enzyme
Eliglustat	Cytochrome P450 3A4	enzyme
Eliglustat	P-glycoprotein 1	transporter
Amphetamine	Sodium-dependent dopamine transporter	target
Amphetamine	Cocaine- and amphetamine-regulated transcript protein	target
Amphetamine	Trace amine-associated receptor 1	target
Amphetamine	Cytochrome P450 2D6	enzyme
Amphetamine	Solute carrier family 22 member 3	transporter
Amphetamine	Solute carrier family 22 member 5	transporter
Amphetamine	Synaptic vesicular amine transporter	target
Amphetamine	Cytochrome P450 2A6	enzyme
Amphetamine	Sodium-dependent noradrenaline transporter	target
Amphetamine	Alpha adrenergic receptor	target
Amphetamine	Beta adrenergic receptor	target
Amphetamine	Dopamine D2 receptor	target
Amphetamine	Amine oxidase [flavin-containing] B	target
Amphetamine	Sodium-dependent serotonin transporter	target
Amphetamine	Monoamine oxidase	target
Amphetamine	vesicular monoamine transporter 2 (VMAT2)	target
Cevimeline	Muscarinic acetylcholine receptor M1	target
Cevimeline	Muscarinic acetylcholine receptor M3	target
Cevimeline	Cytochrome P450 3A4	enzyme
Cevimeline	Cytochrome P450 2D6	enzyme
Cevimeline	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Prochlorperazine	Dopamine D2 receptor	target
Prochlorperazine	Cytochrome P450 2D6	enzyme
Prochlorperazine	Histamine H1 receptor	target
Prochlorperazine	Alpha-1 adrenergic receptors	target
Prochlorperazine	Alpha-2 adrenergic receptors	target
Darifenacin	Muscarinic acetylcholine receptor M3	target
Darifenacin	Cytochrome P450 3A4	enzyme
Darifenacin	Cytochrome P450 2D6	enzyme
Darifenacin	Muscarinic acetylcholine receptor M1	target
Darifenacin	Muscarinic acetylcholine receptor M2	target
Darifenacin	Muscarinic acetylcholine receptor M4	target
Darifenacin	Muscarinic acetylcholine receptor M5	target
Nicergoline	Alpha-1A adrenergic receptor	target
Nicergoline	Cytochrome P450 2D6	enzyme
Dolasetron	5-hydroxytryptamine receptor 3A	target
Dolasetron	Cytochrome P450 3A4	enzyme
Dolasetron	Cytochrome P450 2D6	enzyme
Dolasetron	Cytochrome P450 2C9	enzyme
Minaprine	Dopamine D1 receptor	target
Minaprine	Dopamine D2 receptor	target
Minaprine	5-hydroxytryptamine receptor 2A	target
Minaprine	5-hydroxytryptamine receptor 2B	target
Minaprine	5-hydroxytryptamine receptor 2C	target
Minaprine	Sodium-dependent serotonin transporter	target
Minaprine	Cytochrome P450 2D6	enzyme
Minaprine	Muscarinic acetylcholine receptor M1	target
Minaprine	Acetylcholinesterase	target
Minaprine	Amine oxidase [flavin-containing] A	target
Donepezil	Acetylcholinesterase	target
Donepezil	5-hydroxytryptamine receptor 2A	target
Donepezil	Cytochrome P450 3A4	enzyme
Donepezil	Cytochrome P450 2D6	enzyme
Donepezil	Cytochrome P450 2C9	enzyme
Donepezil	Cholinesterase	target
Donepezil	Nitric oxide synthase, brain	target
Donepezil	Tumor necrosis factor-inducible gene 6 protein	target
Donepezil	Interleukin-1 beta	target
Donepezil	Nuclear factor NF-kappa-B	target
Donepezil	ATP-binding cassette sub-family G member 2	transporter
Donepezil	NMDA receptor	target
Phenformin	5'-AMP-activated protein kinase catalytic subunit alpha-1	target
Phenformin	Cytochrome P450 2D6	enzyme
Phenformin	Solute carrier family 22 member 2	transporter
Phenformin	Solute carrier family 22 member 1	transporter
Phenformin	ATP-sensitive inward rectifier potassium channel 8	target
Almotriptan	5-hydroxytryptamine receptor 1D	target
Almotriptan	5-hydroxytryptamine receptor 1B	target
Almotriptan	Cytochrome P450 3A4	enzyme
Almotriptan	Cytochrome P450 2D6	enzyme
Almotriptan	Amine oxidase [flavin-containing] A	enzyme
Almotriptan	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Almotriptan	Cytochrome P450 2C19	enzyme
Almotriptan	Cytochrome P450 2E1	enzyme
Almotriptan	Cytochrome P450 2C8	enzyme
Procainamide	Sodium channel protein type 5 subunit alpha	target
Procainamide	DNA (cytosine-5)-methyltransferase 1	target
Procainamide	Cytochrome P450 2D6	enzyme
Procainamide	Cholinesterase	enzyme
Procainamide	Solute carrier family 22 member 2	transporter
Procainamide	Solute carrier family 22 member 1	transporter
Procainamide	Solute carrier family 22 member 3	transporter
Procainamide	Solute carrier family 22 member 5	transporter
Procainamide	Solute carrier family 22 member 4	transporter
Procainamide	Potassium voltage-gated channel subfamily H member 2	target
Procainamide	Multidrug and toxin extrusion protein 1	transporter
Procainamide	Multidrug and toxin extrusion protein 2	transporter
Tolterodine	Muscarinic acetylcholine receptor M1	target
Tolterodine	Muscarinic acetylcholine receptor M2	target
Tolterodine	Muscarinic acetylcholine receptor M3	target
Tolterodine	Cytochrome P450 2D6	enzyme
Tolterodine	Cytochrome P450 3A4	enzyme
Tolterodine	Cytochrome P450 2C9	enzyme
Tolterodine	Cytochrome P450 2C19	enzyme
Tolterodine	Muscarinic acetylcholine receptor M4	target
Tolterodine	Muscarinic acetylcholine receptor M5	target
Chlorpheniramine	Histamine H1 receptor	target
Chlorpheniramine	Cytochrome P450 3A4	enzyme
Chlorpheniramine	Cytochrome P450 2D6	enzyme
Chlorpheniramine	Sodium-dependent serotonin transporter	target
Chlorpheniramine	Sodium-dependent noradrenaline transporter	target
Chlorpheniramine	Sodium-dependent dopamine transporter	target
Chlorpheniramine	Cytochrome P450 3A5	enzyme
Chlorpheniramine	Cytochrome P450 3A7	enzyme
Chlorpheniramine	Solute carrier family 22 member 2	transporter
Chlorpheniramine	Solute carrier family 22 member 1	transporter
Encainide	Sodium channel protein type 5 subunit alpha	target
Encainide	Cytochrome P450 2D6	enzyme
Moclobemide	Amine oxidase [flavin-containing] A	target
Moclobemide	Cytochrome P450 2C19	enzyme
Moclobemide	Cytochrome P450 2D6	enzyme
Moclobemide	Amine oxidase [flavin-containing] A	enzyme
Moclobemide	Amine oxidase [flavin-containing] B	enzyme
Moclobemide	Cytochrome P450 2C9	enzyme
Moclobemide	Monoamine oxidase	target
Moclobemide	Amine oxidase [flavin-containing] B	target
Tiotropium	Muscarinic acetylcholine receptor M3	target
Tiotropium	Cytochrome P450 2D6	enzyme
Tiotropium	Cytochrome P450 3A4	enzyme
Tiotropium	Muscarinic acetylcholine receptor M1	target
Tiotropium	Muscarinic acetylcholine receptor M2	target
Tiotropium	Solute carrier family 22 member 5	transporter
Tiotropium	Solute carrier family 22 member 4	transporter
Tiotropium	Muscarinic acetylcholine receptor M4	target
Tiotropium	Muscarinic acetylcholine receptor M5	target
Diphenhydramine	Histamine H1 receptor	target
Diphenhydramine	Cytochrome P450 2D6	enzyme
Diphenhydramine	Cytochrome P450 2C9	enzyme
Diphenhydramine	Cytochrome P450 2C19	enzyme
Diphenhydramine	Solute carrier family 22 member 2	transporter
Diphenhydramine	Solute carrier family 22 member 5	transporter
Diphenhydramine	Prostaglandin G/H synthase 1	enzyme
Diphenhydramine	Muscarinic acetylcholine receptor M2	target
Debrisoquine	Sodium-dependent noradrenaline transporter	target
Debrisoquine	Cytochrome P450 2D6	enzyme
Debrisoquine	P-glycoprotein 1	transporter
Debrisoquine	Cytochrome P450 1A1	enzyme
Gefitinib	Epidermal growth factor receptor	target
Gefitinib	Cytochrome P450 3A4	enzyme
Gefitinib	Cytochrome P450 2D6	enzyme
Gefitinib	P-glycoprotein 1	transporter
Gefitinib	ATP-binding cassette sub-family G member 2	transporter
Gefitinib	Cytochrome P450 3A5	enzyme
Gefitinib	Cytochrome P450 1A1	enzyme
Gefitinib	Cytochrome P450 2C9	enzyme
Gefitinib	Cytochrome P450 2C19	enzyme
Gefitinib	Serum albumin	carrier
Gefitinib	Alpha-1-acid glycoprotein 1	carrier
Terfenadine	Histamine H1 receptor	target
Terfenadine	Potassium voltage-gated channel subfamily H member 2	target
Terfenadine	Cytochrome P450 3A4	enzyme
Terfenadine	Cytochrome P450 2D6	enzyme
Terfenadine	Muscarinic acetylcholine receptor M3	target
Terfenadine	Cytochrome P450 3A5	enzyme
Terfenadine	Cytochrome P450 3A7	enzyme
Terfenadine	P-glycoprotein 1	transporter
Terfenadine	Cytochrome P450 2C8	enzyme
Terfenadine	Cytochrome P450 2J2	enzyme
Terfenadine	Muscarinic acetylcholine receptor M1	target
Terfenadine	Muscarinic acetylcholine receptor M5	target
Terfenadine	Muscarinic acetylcholine receptor M4	target
Terfenadine	Muscarinic acetylcholine receptor M2	target
Terfenadine	Bile salt export pump	transporter
Terfenadine	alpha1-acid glycoprotein	carrier
Terfenadine	Serum albumin	carrier
Diltiazem	Voltage-dependent calcium channel gamma-1 subunit	target
Diltiazem	Cytochrome P450 3A4	enzyme
Diltiazem	Cytochrome P450 2C19	enzyme
Diltiazem	Cytochrome P450 2D6	enzyme
Diltiazem	Cytochrome P450 3A5	enzyme
Diltiazem	Cytochrome P450 3A7	enzyme
Diltiazem	P-glycoprotein 1	transporter
Diltiazem	Cytochrome P450 2C8	enzyme
Diltiazem	Serum albumin	carrier
Diltiazem	Alpha-1-acid glycoprotein 1	carrier
Diltiazem	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Delavirdine	Cytochrome P450 3A4	enzyme
Delavirdine	Cytochrome P450 2C9	enzyme
Delavirdine	Cytochrome P450 2D6	enzyme
Delavirdine	Cytochrome P450 3A5	enzyme
Delavirdine	Cytochrome P450 3A7	enzyme
Delavirdine	Cytochrome P450 2C19	enzyme
Delavirdine	Reverse transcriptase/RNaseH	target
Mesoridazine	Dopamine D2 receptor	target
Mesoridazine	5-hydroxytryptamine receptor 2A	target
Mesoridazine	Cytochrome P450 2D6	enzyme
Mequitazine	Histamine H1 receptor	target
Mequitazine	Cytochrome P450 2D6	enzyme
Mequitazine	Cytochrome P450 3A4	enzyme
Oxymorphone	Mu-type opioid receptor	target
Oxymorphone	Cytochrome P450 2D6	enzyme
Oxymorphone	Delta-type opioid receptor	target
Oxymorphone	Cytochrome P450 3A4	enzyme
Methotrimeprazine	Dopamine D3 receptor	target
Methotrimeprazine	Histamine H1 receptor	target
Methotrimeprazine	Muscarinic acetylcholine receptor M1	target
Methotrimeprazine	Muscarinic acetylcholine receptor M2	target
Methotrimeprazine	Muscarinic acetylcholine receptor M3	target
Methotrimeprazine	Muscarinic acetylcholine receptor M4	target
Methotrimeprazine	Muscarinic acetylcholine receptor M5	target
Methotrimeprazine	Alpha-1A adrenergic receptor	target
Methotrimeprazine	Alpha-1B adrenergic receptor	target
Methotrimeprazine	Alpha-1D adrenergic receptor	target
Methotrimeprazine	Cytochrome P450 2D6	enzyme
Methotrimeprazine	Dopamine D2 receptor	target
Methotrimeprazine	Dopamine D1 receptor	target
Methotrimeprazine	Dopamine D5 receptor	target
Methotrimeprazine	Dopamine D4 receptor	target
Methotrimeprazine	Alpha-2A adrenergic receptor	target
Methotrimeprazine	Alpha-2B adrenergic receptor	target
Methotrimeprazine	Alpha-2C adrenergic receptor	target
Methotrimeprazine	5-hydroxytryptamine receptor 2A	target
Methotrimeprazine	5-hydroxytryptamine receptor 2C	target
Methotrimeprazine	Cytochrome P450 2E1	enzyme
Dihydrocodeine	Cytochrome P450 2D6	enzyme
Dihydrocodeine	Cytochrome P450 3A4	enzyme
Sertindole	5-hydroxytryptamine receptor 2A	target
Sertindole	5-hydroxytryptamine receptor 2C	target
Sertindole	Dopamine D2 receptor	target
Sertindole	Alpha-1A adrenergic receptor	target
Sertindole	Alpha-1B adrenergic receptor	target
Sertindole	Alpha-1D adrenergic receptor	target
Sertindole	Potassium voltage-gated channel subfamily H member 2	target
Sertindole	5-hydroxytryptamine receptor 6	target
Sertindole	Cytochrome P450 2D6	enzyme
Sertindole	Cytochrome P450 3A4	enzyme
Tesmilifene	P-glycoprotein 1	target
Tesmilifene	Histamine H1 receptor	target
Tesmilifene	Cytochrome P450 3A4	enzyme
Tesmilifene	Cytochrome P450 2D6	enzyme
Tesmilifene	Cytochrome P450 1A1	enzyme
Rotigotine	Dopamine D3 receptor	target
Rotigotine	Dopamine D5 receptor	target
Rotigotine	Dopamine D4 receptor	target
Rotigotine	Dopamine D2 receptor	target
Rotigotine	5-hydroxytryptamine receptor 1A	target
Rotigotine	Dopamine D1 receptor	target
Rotigotine	Cytochrome P450 2D6	enzyme
Rotigotine	Cytochrome P450 3A4	enzyme
Rotigotine	Alpha-2B adrenergic receptor	target
Rotigotine	Cytochrome P450 2C19	enzyme
Lisuride	Dopamine D1 receptor	target
Lisuride	5-hydroxytryptamine receptor 1A	target
Lisuride	Dopamine D2 receptor	target
Lisuride	Alpha-2A adrenergic receptor	target
Lisuride	Alpha-2B adrenergic receptor	target
Lisuride	Alpha-2C adrenergic receptor	target
Lisuride	Dopamine D3 receptor	target
Lisuride	5-hydroxytryptamine receptor 1D	target
Lisuride	5-hydroxytryptamine receptor 2B	target
Lisuride	5-hydroxytryptamine receptor 2A	target
Lisuride	Dopamine D4 receptor	target
Lisuride	5-hydroxytryptamine receptor 2C	target
Lisuride	Dopamine D5 receptor	target
Lisuride	5-hydroxytryptamine receptor 1B	target
Lisuride	Cytochrome P450 3A4	enzyme
Lisuride	5-hydroxytryptamine receptor 7	target
Trabectedin	Cytochrome P450 3A4	enzyme
Trabectedin	Cytochrome P450 2C9	enzyme
Trabectedin	Cytochrome P450 2D6	enzyme
Trabectedin	Cytochrome P450 2E1	enzyme
Trabectedin	Cytochrome P450 2C19	enzyme
Trabectedin	DNA	target
Trabectedin	Prostaglandin G/H synthase 1	enzyme
4-Methoxyamphetamine	Alpha-1A adrenergic receptor	target
4-Methoxyamphetamine	Alpha-2A adrenergic receptor	target
4-Methoxyamphetamine	Cytochrome P450 2D6	enzyme
4-Methoxyamphetamine	Sodium-dependent dopamine transporter	target
4-Methoxyamphetamine	Sodium-dependent serotonin transporter	target
4-Methoxyamphetamine	Amine oxidase [flavin-containing] A	target
4-Methoxyamphetamine	Amine oxidase [flavin-containing] B	target
4-Methoxyamphetamine	Synaptic vesicular amine transporter	target
Sparteine	Cytochrome P450 2D6	enzyme
Ticlopidine	P2Y purinoceptor 12	target
Ticlopidine	Cytochrome P450 2C19	enzyme
Ticlopidine	Cytochrome P450 2B6	enzyme
Ticlopidine	Cytochrome P450 2C9	enzyme
Ticlopidine	Cytochrome P450 2D6	enzyme
Ticlopidine	Myeloperoxidase	enzyme
Ticlopidine	Cytochrome P450 1A2	enzyme
Ticlopidine	Cytochrome P450 2C8	enzyme
Ticlopidine	Cytochrome P450 2E1	enzyme
Amoxapine	Sodium-dependent serotonin transporter	target
Amoxapine	Sodium-dependent noradrenaline transporter	target
Amoxapine	Alpha-2A adrenergic receptor	target
Amoxapine	Dopamine D2 receptor	target
Amoxapine	Alpha-1A adrenergic receptor	target
Amoxapine	Dopamine D1 receptor	target
Amoxapine	Muscarinic acetylcholine receptor M1	target
Amoxapine	Gamma-aminobutyric acid receptor subunit alpha-1	target
Amoxapine	Alpha-1-acid glycoprotein 1	carrier
Amoxapine	Cytochrome P450 2D6	enzyme
Amoxapine	5-hydroxytryptamine receptor 2A	target
Amoxapine	5-hydroxytryptamine receptor 2C	target
Amoxapine	5-hydroxytryptamine receptor 6	target
Amoxapine	5-hydroxytryptamine receptor 7	target
Amoxapine	Dopamine D3 receptor	target
Amoxapine	Dopamine D4 receptor	target
Amoxapine	Histamine H1 receptor	target
Amoxapine	Alpha-1 adrenergic receptors	target
Amoxapine	Muscarinic acetylcholine receptor	target
Amoxapine	5-hydroxytryptamine receptor 2B	target
Amoxapine	5-hydroxytryptamine receptor 3A	target
Amoxapine	5-hydroxytryptamine receptor 1A	target
Amoxapine	5-hydroxytryptamine receptor 1B	target
Amoxapine	Alpha-2 adrenergic receptors	target
Amoxapine	Histamine H4 receptor	target
Amoxapine	GABA(A) Receptor	target
Amoxapine	Sodium-dependent dopamine transporter	target
Chloroquine	Tumor necrosis factor	target
Chloroquine	Toll-like receptor 9	target
Chloroquine	Glutathione S-transferase A2	target
Chloroquine	Cytochrome P450 2D6	enzyme
Chloroquine	Cytochrome P450 3A4	enzyme
Chloroquine	Cytochrome P450 1A1	enzyme
Chloroquine	Cytochrome P450 2C8	enzyme
Chloroquine	Cytochrome P450 3A5	enzyme
Chloroquine	Glutathione S-transferase	target
Chloroquine	P-glycoprotein 1	transporter
Chloroquine	Serum albumin	carrier
Chloroquine	alpha1-acid glycoprotein	carrier
Chloroquine	High mobility group protein B1	target
Chloroquine	Glutathione S-transferase Mu 1	target
Chloroquine	Angiotensin-converting enzyme 2	target
Iloperidone	Dopamine D2 receptor	target
Iloperidone	5-hydroxytryptamine receptor 2A	target
Iloperidone	Cytochrome P450 2D6	enzyme
Iloperidone	Cytochrome P450 3A4	enzyme
Iloperidone	Cytochrome P450 3A5	enzyme
Iloperidone	Cytochrome P450 3A7	enzyme
Iloperidone	Cytochrome P450 2E1	enzyme
Iloperidone	Dopamine D3 receptor	target
Iloperidone	Alpha-1A adrenergic receptor	target
Iloperidone	Dopamine D4 receptor	target
Iloperidone	5-hydroxytryptamine receptor 6	target
Iloperidone	5-hydroxytryptamine receptor 7	target
Iloperidone	Histamine H1 receptor	target
Iloperidone	Dopamine D1 receptor	target
Iloperidone	5-hydroxytryptamine receptor 1A	target
Iloperidone	Alpha-2C adrenergic receptor	target
Metamfetamine	Cytochrome P450 2D6	enzyme
Metamfetamine	Solute carrier family 22 member 3	transporter
Metamfetamine	Solute carrier family 22 member 5	transporter
Metamfetamine	Sodium-dependent dopamine transporter