Antihypertensive Agents Indicated for Hypertension
- Name
- Antihypertensive Agents Indicated for Hypertension
- Accession Number
- DBCAT005157
- Description
Included in this category are agents that have approved indications for the treatment of hypertension. Not included in this category are agents that may result in a blood pressure-lowering effect as part of an adverse effect profile or via activity at off-targets (i.e. agents that may decrease blood pressure but are not officially indicated clinically for this purpose).
- Drugs
Drug Drug Description Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Aliskiren A direct renin inhibitor used to manage hypertension. Amlodipine A calcium channel blocker used to treat hypertension and angina. Atenolol A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. Azilsartan medoxomil An angiotensin II receptor blocker used to treat hypertension alone or in combination with other antihypertensive agents, such as chlorthalidone. Benazepril An ACE inhibitor prodrug used to treat hypertension. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Betaxolol A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). Bisoprolol A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. Candesartan cilexetil An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Cilazapril An ACE inhibitor used for the management of hypertension and heart failure. Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Doxazosin An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. Enalapril A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. Enalaprilat An antihypertensive agent used for the management of hypertension when oral therapy is not practical. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Eprosartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Esmolol A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension. Felodipine A calcium channel blocker used to treat hypertension. Fenoldopam A dopamine D1 receptor agonist used for the short term management of hypertension. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Guanfacine An alpha-2A adrenergic receptor agonist used to treat ADHD. Hydralazine An antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia . Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Irbesartan An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure. Isradipine A dihydropyridine calcium channel blocker used for the treatment of hypertension. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Levamlodipine A calcium channel blocker used to treat hypertension. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Losartan An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. Mecamylamine A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Metolazone A thiazide-like diuretic used to treat hypertension. Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. Minoxidil An antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. Moexipril An angiotensin converting enzyme inhibitor prodrug used to treat hypertension. Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. Nebivolol A beta blocking agent used to treat hypertension and aid in the management of heart failure. Nicardipine A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Nisoldipine A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. Olmesartan An angiotensin receptor blocker (ARB) used in the treatment of hypertension. Perindopril An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Prazosin An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Quinapril An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease. Ramipril An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure. Reserpine For the treatment of hypertension Spironolactone An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism. Telmisartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. Terazosin An alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension. Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Trandolapril A prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction. Valsartan An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. Verapamil A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. - Drugs & Drug Targets