Presbyopia

Also known as: Presbyopias

Drug	Drug Name	Drug Description
DB01085	Pilocarpine	A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.

Drug	Drug Name	Target	Type
DB01085	Pilocarpine	Muscarinic acetylcholine receptor M1	target
DB01085	Pilocarpine	Muscarinic acetylcholine receptor M2	target
DB01085	Pilocarpine	Cytochrome P450 2A6	enzyme
DB01085	Pilocarpine	Muscarinic acetylcholine receptor M3	target
DB01085	Pilocarpine	Cytochrome P450 3A4	enzyme
DB01085	Pilocarpine	Muscarinic acetylcholine receptor M4	target
DB01085	Pilocarpine	Muscarinic acetylcholine receptor M5	target
DB01085	Pilocarpine	Serum paraoxonase/arylesterase 1	enzyme

Drug	Drug Name	Phase	Status	Count
DB00484	Brimonidine	0	Unknown Status	1
DB01085	Pilocarpine	0	Unknown Status	1
DB13262	Aceclidine	1	Completed	1
DB00484	Brimonidine	1	Completed	2
DB00484	Brimonidine	1	Recruiting	2
DB00963	Bromfenac	1	Recruiting	2
DB08818	Hyaluronic acid	1	Recruiting	2
DB00935	Oxymetazoline	1	Completed	1
DB00935	Oxymetazoline	1	Recruiting	2
DB01085	Pilocarpine	1	Completed	1
DB01085	Pilocarpine	1	Recruiting	2
DB13262	Aceclidine	2	Completed	3
DB00484	Brimonidine	2	Completed	3
DB00411	Carbamoylcholine	2	Completed	1
DB14547	Chloride ion	2	Completed	1
DB00122	Choline	2	Completed	1
DB00166	Lipoic acid	2	Completed	1
DB00692	Phentolamine	2	Completed	1
DB01085	Pilocarpine	2	Completed	2
DB00809	Tropicamide	2	Completed	1
DB13262	Aceclidine	3	Active Not Recruiting	1
DB13262	Aceclidine	3	Completed	2
DB13262	Aceclidine	3	Recruiting	1
DB00484	Brimonidine	3	Active Not Recruiting	1
DB00484	Brimonidine	3	Completed	3
DB00484	Brimonidine	3	Recruiting	2
DB00411	Carbamoylcholine	3	Completed	1
DB00411	Carbamoylcholine	3	Recruiting	1
DB00692	Phentolamine	3	Completed	1
DB01085	Pilocarpine	3	Active Not Recruiting	1
DB01085	Pilocarpine	3	Completed	8
DB00305	Mitomycin	4	Terminated	1
DB00305	Mitomycin	4	Unknown Status	2