Premature Ejaculation

Also known as: Premature ejaculation / Premature ejaculation disorder / Ejaculatio praecox / Ejaculation premature

DrugDrug NameDrug Description
DB01086BenzocaineA topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
DB00215CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
DB04884DapoxetineA selective serotonin reuptake inhibitor used in the treatment of premature ejaculation.
DB00472FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
DB00715ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
DB00203SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DB00193TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
DrugDrug NameTargetType
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineP-glycoprotein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01086BenzocaineCytochrome P450 1A2enzyme
DB01086BenzocaineCytochrome P450 2B6enzyme
DB01086BenzocaineCytochrome P450 2C19enzyme
DB01086BenzocaineCytochrome P450 2D6enzyme
DB01086BenzocaineCytochrome P450 2E1enzyme
DB01086BenzocaineSerum albumincarrier
DB01086Benzocainealpha1-acid glycoproteincarrier
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramP-glycoprotein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramHistamine H1 receptortarget
DB00215CitalopramAmine oxidase [flavin-containing] Aenzyme
DB00215CitalopramAmine oxidase [flavin-containing] Benzyme
DB00215CitalopramAldehyde oxidaseenzyme
DB04884Dapoxetine5-hydroxytryptamine receptor 1Atarget
DB04884Dapoxetine5-hydroxytryptamine receptor 1Btarget
DB04884Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DB04884DapoxetineCytochrome P450 3A4enzyme
DB04884DapoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineP-glycoprotein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineP-glycoprotein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00715ParoxetineAlpha-1 adrenergic receptorstarget
DB00715ParoxetineAlpha-2 adrenergic receptorstarget
DB00715ParoxetineBeta adrenergic receptortarget
DB00715ParoxetineDopamine D2 receptortarget
DB00715ParoxetineHistamine H1 receptortarget
DB00715ParoxetineSerotonin Receptorstarget
DB00715ParoxetineMuscarinic acetylcholine receptortarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineD(1) dopamine receptortarget
DB00715ParoxetineCytochrome P450 2C19enzyme
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilP-glycoprotein 1transporter
DB00203SildenafilOrnithine decarboxylasetarget
DB00203SildenafilProgrammed cell death 1 ligand 1target
DB00193TramadolMu-type opioid receptortarget
DB00193TramadolSodium-dependent noradrenaline transportertarget
DB00193Tramadol5-hydroxytryptamine receptor 2Ctarget
DB00193TramadolKappa-type opioid receptortarget
DB00193TramadolSodium-dependent serotonin transportertarget
DB00193TramadolCytochrome P450 2D6enzyme
DB00193TramadolDelta-type opioid receptortarget
DB00193TramadolCytochrome P450 3A4enzyme
DB00193TramadolCytochrome P450 2B6enzyme
DB00193TramadolNeuronal acetylcholine receptor subunit alpha-7target
DB00193TramadolMuscarinic acetylcholine receptor M3target
DB00193TramadolMuscarinic acetylcholine receptor M1target
DB00193TramadolUDP-glucuronosyltransferase 1-1enzyme
DB00193TramadolNeurokinin 1 receptortarget
DB00193TramadolSodium channel protein type 2 subunit alphatarget
DB00193TramadolTransient receptor potential cation channel subfamily V member 1target
DB00193TramadolNMDA receptortarget
DB00193TramadolAdenosine receptor A1target
DB00193TramadolAlpha-2 adrenergic receptorstarget
DrugDrug NamePhaseStatusCount
DB01175Escitalopram0Unknown Status1
DB11934Epelsiban1Completed1
DB11818Retosiban1Terminated1
DB04884Dapoxetine1 / 2Completed2
DB00083Botulinum toxin type A2Terminated1
DB01242Clomipramine2Completed1
DB11934Epelsiban2Completed1
DB04903Pagoclone2Completed1
DB00203Sildenafil2Not Yet Recruiting1
DB06207Silodosin2Unknown Status1
DB00281Lidocaine2 / 3Completed1
DB00750Prilocaine2 / 3Completed1
DB00126Ascorbic acid3Completed1
DB01242Clomipramine3Completed1
DB00115Cyanocobalamin3Completed1
DB04884Dapoxetine3Completed1
DB04884Dapoxetine3Recruiting1
DB04884Dapoxetine3Unknown Status1
DB00158Folic acid3Completed1
DB08818Hyaluronic acid3Completed1
DB00281Lidocaine3Recruiting1
DB00281Lidocaine3Unknown Status1
DB00627Niacin3Completed1
DB00715Paroxetine3Completed1
DB00715Paroxetine3Unknown Status1
DB00165Pyridoxine3Completed1
DB00140Riboflavin3Completed1
DB00820Tadalafil3Not Yet Recruiting1
DB00820Tadalafil3Recruiting1
DB00820Tadalafil3Unknown Status1
DB00706Tamsulosin3Unknown Status1
DB00152Thiamine3Completed1
DB00193Tramadol3Terminated1
DB00162Vitamin A3Completed1
DB11094Vitamin D3Completed1
DB00163Vitamin E3Completed1
DB04884Dapoxetine4Completed1
DB04884Dapoxetine4Not Yet Recruiting1
DB00203Sildenafil4Completed1
DB00203Sildenafil4Not Yet Recruiting1
DB00820Tadalafil4Not Yet Recruiting1
DB00193Tramadol4Not Yet Recruiting1
DB04884DapoxetineNot AvailableCompleted1
DB04884DapoxetineNot AvailableUnknown Status2
DB00281LidocaineNot AvailableRecruiting1
DB00715ParoxetineNot AvailableRecruiting1