Arthritis

Also known as: Articular inflammation / Inflammatory arthritis / Arthritis (finding) / Arthritis (disorder) / (Arthropathy NOS) or (arthritis) / Inflammatory disorder of joint (disorder) / Arthritis NOS / Arthrosis NOS

DrugDrug NameDrug Description
DB11344(+)-mentholNot Annotated
DB11345(S)-camphorIndicated for the temporary symptomatic relief of minor aches and pains of muscles and joints in topical analgesics.
DB111742-(l-menthoxy)ethanolNot Annotated
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB11288BorneolNot Annotated
DB01744CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
DB06774CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
DB01401Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
DB09301Chondroitin sulfateChondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
DB15576Ethyl salicylateA salicylate indicated in the treatment of sports related pain.
DB11114Eucalyptus oilAn ingredient used in a variety of natural health products.
DB01296GlucosamineA common ingredient in nutritional supplements used for the relief of joint pain.
DB00825LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
DB11201Menthyl salicylateFor the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis .
DB00423MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
DB09543Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DB01173OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
DB00812PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
DB00165PyridoxineA vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.
DB02513ThymolAn essential oil found in various over-the-counter antibacterial and antifungal products.
DB11120TurpentineA medication used to treat minor aches and pains of muscles and joints.
DrugDrug NameTargetType
DB11345(S)-camphorTransient receptor potential cation channel subfamily V member 1target
DB11345(S)-camphorTransient receptor potential cation channel subfamily V member 3target
DB11345(S)-camphorTransient receptor potential cation channel subfamily A member 1target
DB11345(S)-camphorTransient receptor potential cation channel subfamily M member 8target
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00945Acetylsalicylic acidSialidase-1target
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinMyeloperoxidaseenzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinCholinesteraseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB06774CapsaicinProhibitin-2target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 1target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB09301Chondroitin sulfateBrain-derived neurotrophic factortarget
DB09301Chondroitin sulfateGlial cell line-derived neurotrophic factortarget
DB09301Chondroitin sulfateVascular endothelial growth factor Atarget
DB09301Chondroitin sulfateC-C motif chemokine 2target
DB09301Chondroitin sulfateBeta-glucuronidaseenzyme
DB09301Chondroitin sulfateBeta-hexosaminidase subunit betaenzyme
DB09301Chondroitin sulfateN-acetylgalactosamine-6-sulfataseenzyme
DB09301Chondroitin sulfateIduronate 2-sulfataseenzyme
DB09301Chondroitin sulfateAlpha-L-iduronidaseenzyme
DB09301Chondroitin sulfateArylsulfatase Benzyme
DB01296GlucosamineInterferon gammatarget
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 2transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 1transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 4transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 3transporter
DB01296GlucosamineTranscription factor p65target
DB00825LevomentholTransient receptor potential cation channel subfamily A member 1target
DB00825LevomentholTransient receptor potential cation channel subfamily M member 8target
DB00825LevomentholTransient receptor potential cation channel subfamily V member 3target
DB00825LevomentholKappa-type opioid receptortarget
DB00825LevomentholVoltage-dependent L-type calcium channeltarget
DB00825LevomentholCytochrome P450 3A4enzyme
DB11201Menthyl salicylateProstaglandin G/H synthase 1target
DB11201Menthyl salicylateProstaglandin G/H synthase 2target
DB00423MethocarbamolCarbonic anhydrase 1target
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenP-glycoprotein 1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1-3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-10enzyme
DB00788NaproxenSolute carrier family 22 member 8transporter
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01173OrphenadrineCytochrome P450 2D6enzyme
DB01173OrphenadrineSerum albumincarrier
DB00812PhenylbutazoneProstaglandin G/H synthase 2target
DB00812PhenylbutazoneProstacyclin synthasetarget
DB00812PhenylbutazoneCytochrome P450 2C9enzyme
DB00812PhenylbutazoneSolute carrier family 22 member 6transporter
DB00812PhenylbutazoneSolute carrier family 22 member 8transporter
DB00812PhenylbutazoneSolute carrier family 22 member 11transporter
DB00812PhenylbutazoneProstaglandin G/H synthase 1target
DB00812PhenylbutazoneCytochrome P450 3A4enzyme
DB00165PyridoxinePyridoxal kinasetarget
DB00165PyridoxineCytochrome P450 1A1enzyme
DB00165PyridoxineSerum albumincarrier
DB00165PyridoxinePyridoxal kinaseenzyme
DB00165PyridoxinePyridoxal phosphate phosphataseenzyme
DB00165PyridoxineAlkaline phosphatase, tissue-nonspecific isozymetransporter
DB00165PyridoxineAlkaline phosphatase, tissue-nonspecific isozymeenzyme
DB11120TurpentineMitogen-activated protein kinase 1target
DrugDrug NamePhaseStatusCount
DB15291BMS-9861421Completed2
DB04272Citric acid1Withdrawn1
DB00586Diclofenac1Completed1
DB00736Esomeprazole1Completed1
DB17331Imvotamab1Recruiting1
DB00788Naproxen1Completed3
DB09154Sodium citrate1Withdrawn1
DB16035BFH7721 / 2Completed1
DB00443Betamethasone1 / 2Completed1
DB02300Calcipotriol1 / 2Completed1
DB00482Celecoxib1 / 2Not Yet Recruiting1
DB00331Metformin1 / 2Not Yet Recruiting1
DB00563Methotrexate1 / 2Completed1
DB00688Mycophenolate mofetil1 / 2Completed1
DB01024Mycophenolic acid1 / 2Completed1
DB13127Olokizumab1 / 2Completed1
DB00177Valsartan1 / 2Not Yet Recruiting1
DB00051Adalimumab2Completed1
DB00083Botulinum toxin type A2Unknown Status1
DB00586Diclofenac2Recruiting1
DB11938Difelikefalin2Completed1
DB11621Human varicella-zoster immune globulin2Active Not Recruiting1
DB11621Human varicella-zoster immune globulin2Completed1
DB01611Hydroxychloroquine2Recruiting1
DB00563Methotrexate2Not Yet Recruiting1
DB00635Prednisone2Recruiting1
DB12335Tanezumab2Completed1
DB00620Triamcinolone2Withdrawn1
DB12353Ulodesine2Completed2
DB10318Varicella zoster vaccine (live/attenuated)2Active Not Recruiting1
DB10318Varicella zoster vaccine (live/attenuated)2Completed1
DB11105Benzalkonium2 / 3Unknown Status1
DB16130Dapansutrile2 / 3Recruiting1
DB00005Etanercept2 / 3Unknown Status1
DB00065Infliximab2 / 3Withdrawn1
DB01281Abatacept3Completed1
DB00316Acetaminophen3Recruiting1
DB00051Adalimumab3Completed1
DB00083Botulinum toxin type A3Unknown Status1
DB00482Celecoxib3Completed3
DB00736Esomeprazole3Completed1
DB06674Golimumab3Completed1
DB00563Methotrexate3Completed1
DB00788Naproxen3Completed2
DB00788Naproxen3Recruiting1
DB00497Oxycodone3Completed1
DB06228Rivaroxaban3Completed1
DB12335Tanezumab3Completed3
DB12335Tanezumab3Terminated2
DB06204Tapentadol3Completed1
DB13076Yttrium Y-903Completed1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Terminated1
DB00051Adalimumab4Completed1
DB00051Adalimumab4Unknown Status1
DB00297Bupivacaine4Completed2
DB01189Desflurane4Completed1
DB01234Dexamethasone4Completed1
DB01234Dexamethasone4Unknown Status1
DB00668Epinephrine4Completed1
DB00813Fentanyl4Completed2
DB00563Methotrexate4Unknown Status1
DB00497Oxycodone4Terminated1
DB00818Propofol4Completed1
DB00302Tranexamic acid4Withdrawn1
DB00316AcetaminophenNot AvailableCompleted1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB01217AnastrozoleNot AvailableUnknown Status1
DB00181BaclofenNot AvailableCompleted1
DB00297BupivacaineNot AvailableCompleted1
DB06774CapsaicinNot AvailableCompleted1
DB00924CyclobenzaprineNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB00005EtanerceptNot AvailableCompleted1
DB01628EtoricoxibNot AvailableCompleted1
DB00712FlurbiprofenNot AvailableCompleted1
DB00996GabapentinNot AvailableCompleted1
DB01050IbuprofenNot AvailableCompleted1
DB01221KetamineNot AvailableCompleted1
DB01006LetrozoleNot AvailableUnknown Status1
DB00825LevomentholNot AvailableCompleted1
DB00825LevomentholNot AvailableUnknown Status1
DB00281LidocaineNot AvailableCompleted1
DB00281LidocaineNot AvailableUnknown Status1
DB00814MeloxicamNot AvailableCompleted1
DB14123MentholNot AvailableUnknown Status1
DB00563MethotrexateNot AvailableCompleted1
DB00860PrednisoloneNot AvailableCompleted1
DB00750PrilocaineNot AvailableCompleted1
DB00669SumatriptanNot AvailableCompleted1
DB00697TizanidineNot AvailableCompleted1
DB06273TocilizumabNot AvailableCompleted1
DB00273TopiramateNot AvailableCompleted1