Edema

Also known as: Oedema / Edema NOS / Edematous / Oedema NOS / Edema (NOS) / Fluid retention NOS

DrugDrug NameDrug Description
DB00819AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
DB00887BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
DB15861ButhiazideA diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases.
DB09015Canrenoic acidAn aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels.
DB12221CanrenoneAn antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure).
DB00880ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
DB00310ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB00903Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
DB00695FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DB13490HidrosminA synthetic bioflavonoid used for the short-term treatment of symptoms associated with chronic venous insufficiency.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB00774HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
DB16584Liprotamase proteaseAn anti-inflammatory indicated for a wide variety of inflammatory conditions.
DB00232MethyclothiazideA diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy.
DB00524MetolazoneA thiazide-like diuretic used to treat hypertension.
DB02925PiretanideA loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin.
DB01324PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
DB14631Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
DB00421SpironolactoneAn aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism.
DB00214TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
DB00384TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
DB13803XipamideA diuretic indicated in the treatment of edema.
DrugDrug NameTargetType
DB00819AcetazolamideCarbonic anhydrase 1target
DB00819AcetazolamideAquaporin-1target
DB00819AcetazolamideCarbonic anhydrase 14target
DB00819AcetazolamideSolute carrier family 22 member 6transporter
DB00819AcetazolamideCarbonic anhydrase 2target
DB00819AcetazolamideCarbonic anhydrase 3target
DB00819AcetazolamideCarbonic anhydrase 4target
DB00819AcetazolamideCytochrome P450 3A4enzyme
DB00819AcetazolamideCarbonic anhydrase 7target
DB00819AcetazolamideCarbonic anhydrase 12target
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00880ChlorothiazideSolute carrier family 12 member 3target
DB00880ChlorothiazideCarbonic anhydrase 1target
DB00880ChlorothiazideCarbonic anhydrase 2target
DB00880ChlorothiazideSolute carrier family 22 member 6transporter
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00903Etacrynic acidSolute carrier family 12 member 1target
DB00903Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
DB00903Etacrynic acidGlutathione S-transferase A2enzyme
DB00903Etacrynic acidSerum albumincarrier
DB00903Etacrynic acidSolute carrier family 22 member 6transporter
DB00903Etacrynic acidLymphoid enhancer-binding factor 1target
DB00903Etacrynic acidGlutathione S-transferase Ptarget
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00695FurosemideG-protein coupled receptor 35target
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00774HydroflumethiazideSerum albumincarrier
DB00774HydroflumethiazideSolute carrier family 22 member 6transporter
DB00774HydroflumethiazideSolute carrier family 22 member 8transporter
DB00774HydroflumethiazideCarbonic anhydrase 7target
DB00232MethyclothiazideSolute carrier family 12 member 1target
DB00232MethyclothiazideCarbonic anhydrase 4target
DB00232MethyclothiazideCarbonic anhydrase 2target
DB00232MethyclothiazideCarbonic anhydrase 1target
DB00524MetolazoneSolute carrier family 12 member 3target
DB02925PiretanideSolute carrier family 12 member 1target
DB01324PolythiazideSolute carrier family 12 member 3target
DB01324PolythiazideSolute carrier family 22 member 6transporter
DB01324PolythiazideSolute carrier family 22 member 8transporter
DB01324PolythiazideSerum albumincarrier
DB14631Prednisolone phosphateCytochrome P450 3A4enzyme
DB14631Prednisolone phosphateCytochrome P450 3A5enzyme
DB14631Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
DB14631Prednisolone phosphateCytochrome P450 2A6enzyme
DB14631Prednisolone phosphateCytochrome P450 1B1enzyme
DB14631Prednisolone phosphateCytochrome P450 2B6enzyme
DB14631Prednisolone phosphateCytochrome P450 2C8enzyme
DB14631Prednisolone phosphateCytochrome P450 2C9enzyme
DB14631Prednisolone phosphateCytochrome P450 2C19enzyme
DB14631Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB14631Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB14631Prednisolone phosphateGlucocorticoid receptortarget
DB14631Prednisolone phosphateAnnexin A1target
DB14631Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
DB14631Prednisolone phosphateP-glycoprotein 1transporter
DB14631Prednisolone phosphateSolute carrier family 22 member 8transporter
DB14631Prednisolone phosphateCorticosteroid-binding globulincarrier
DB14631Prednisolone phosphateSerum albumincarrier
DB00421SpironolactoneMineralocorticoid receptortarget
DB00421SpironolactoneCytochrome P450 2C8enzyme
DB00421SpironolactoneCanalicular multispecific organic anion transporter 1transporter
DB00421SpironolactoneP-glycoprotein 1transporter
DB00421SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
DB00421SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
DB00421SpironolactoneAndrogen receptortarget
DB00421SpironolactoneProgesterone receptortarget
DB00421SpironolactoneGlucocorticoid receptortarget
DB00421SpironolactoneNuclear receptor subfamily 1 group I member 2target
DB00421SpironolactoneBile salt export pumptransporter
DB00421SpironolactoneSerum albumincarrier
DB00421Spironolactonealpha1-acid glycoproteincarrier
DB00421SpironolactoneEstrogen receptortarget
DB00421SpironolactoneCytochrome P450 11B2, mitochondrialenzyme
DB00421SpironolactoneVoltage-dependent L-type calcium channeltarget
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier organic anion transporter family member 1B1transporter
DB00214TorasemideSolute carrier family 12 member 2target
DB00214TorasemideSerum albumincarrier
DB00384TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
DB00384TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
DB00384TriamtereneAmiloride-sensitive sodium channel subunit betatarget
DB00384TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
DB00384TriamtereneCytochrome P450 1A2enzyme
DrugDrug NamePhaseStatusCount
DB05394Corticorelin1Completed1
DB00695Furosemide1Completed1
DB08885Aflibercept2Recruiting1
DB00958Carboplatin2Active Not Recruiting1
DB00950Fexofenadine2Completed1
DB09106Hydroxyethyl Starch2Completed1
DB01229Paclitaxel2Active Not Recruiting1
DB01269Panitumumab2Active Not Recruiting1
DB09037Pembrolizumab2Active Not Recruiting1
DB06212Tolvaptan2Completed1
DB00062Albumin human3Completed1
DB00594Amiloride3Terminated1
DB00695Furosemide3Terminated1
DB00819Acetazolamide4Completed1
DB01234Dexamethasone4Completed2
DB00749Etodolac4Completed1
DB00695Furosemide4Completed2
DB14740Hyaluronidase4Completed1
DB00999Hydrochlorothiazide4Completed1
DB06725Lornoxicam4Completed1
DB00302Tranexamic acid4Completed1
DB00302Tranexamic acid4Not Yet Recruiting1
DB00945Acetylsalicylic acidNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB01118AmiodaroneNot AvailableRecruiting1
DB00182AmphetamineNot AvailableRecruiting1
DB00026AnakinraNot AvailableRecruiting1
DB14297Arnica montanaNot AvailableCompleted1
DB00207AzithromycinNot AvailableRecruiting1
DB00559BosentanNot AvailableRecruiting1
DB01222BudesonideNot AvailableRecruiting1
DB06168CanakinumabNot AvailableRecruiting1
DB00535CefdinirNot AvailableRecruiting1
DB01413CefepimeNot AvailableRecruiting1
DB00438CeftazidimeNot AvailableRecruiting1
DB01190ClindamycinNot AvailableRecruiting1
DB00349ClobazamNot AvailableRecruiting1
DB00318CodeineNot AvailableCompleted1
DB01394ColchicineNot AvailableRecruiting1
DB01234DexamethasoneNot AvailableCompleted2
DB01234DexamethasoneNot AvailableRecruiting1
DB01234DexamethasoneNot AvailableUnknown Status1
DB09214DexketoprofenNot AvailableUnknown Status1
DB00633DexmedetomidineNot AvailableRecruiting1
DB00586DiclofenacNot AvailableCompleted1
DB00668EpinephrineNot AvailableUnknown Status1
DB01628EtoricoxibNot AvailableUnknown Status1
DB00828FosfomycinNot AvailableRecruiting1
DB00695FurosemideNot AvailableRecruiting1
DB00996GabapentinNot AvailableRecruiting1
DB01018GuanfacineNot AvailableRecruiting1
DB00741HydrocortisoneNot AvailableRecruiting1
DB01050IbuprofenNot AvailableUnknown Status1
DB00598LabetalolNot AvailableRecruiting1
DB06707LevonordefrinNot AvailableUnknown Status1
DB01601LopinavirNot AvailableRecruiting1
DB00961MepivacaineNot AvailableUnknown Status1
DB00760MeropenemNot AvailableRecruiting1
DB00331MetforminNot AvailableRecruiting1
DB00959MethylprednisoloneNot AvailableCompleted1
DB00235MilrinoneNot AvailableRecruiting1
DB00844NalbuphineNot AvailableRecruiting1
DB00622NicardipineNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00198OseltamivirNot AvailableRecruiting1
DB00497OxycodoneNot AvailableRecruiting1
DB14761RemdesivirNot AvailableRecruiting1
DB00811RibavirinNot AvailableRecruiting1
DB00734RisperidoneNot AvailableRecruiting1
DB00503RitonavirNot AvailableRecruiting1
DB08877RuxolitinibNot AvailableRecruiting1
DB11767SarilumabNot AvailableRecruiting1
DB01104SertralineNot AvailableRecruiting1
DB00658SevelamerNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB00871TerbutalineNot AvailableRecruiting1
DB06273TocilizumabNot AvailableRecruiting1
DB00214TorasemideNot AvailableCompleted2
DB00302Tranexamic acidNot AvailableRecruiting1
DB00582VoriconazoleNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1