Ventricular Arrhythmia

Also known as: Ventricular arrhythmia NOS / Arrhythmia of ventricular origin / Ventricular Arrhythmias / Ventricula arrhythmia / Ventricular Arrythmias / Arrhythmias Ventricular / Arrhythmia ventricular / Arrhythmia, Ventricular / Ventricular Arrythmia / Ventricular dysrhythmias / Arrhythmia ventricular (NOS) / Ventricular arrhythmia (disorder) / Ventricular dysrhythmia

DrugDrug NameDrug Description
DB01193AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
DB00390DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
DB00280DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
DB14600Edetate disodium anhydrousA polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
DB01064IsoprenalineA catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB00379MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
DB01182PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB00243RanolazineAn anti-anginal drug used for the treatment of chronic angina.
DrugDrug NameTargetType
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololP-glycoprotein 1transporter
DB00390DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00390DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00390DigoxinP-glycoprotein 1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 4C1transporter
DB00390DigoxinBile salt export pumptransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1A2transporter
DB00390DigoxinOrganic solute transporter subunit alphatransporter
DB00390DigoxinOrganic solute transporter subunit betatransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B1transporter
DB00280DisopyramideSodium channel protein type 5 subunit alphatarget
DB00280DisopyramideAlpha-1-acid glycoprotein 1carrier
DB00280DisopyramideCytochrome P450 3A4enzyme
DB00280DisopyramideMuscarinic acetylcholine receptor M1target
DB00280DisopyramideMuscarinic acetylcholine receptor M2target
DB00280DisopyramideMuscarinic acetylcholine receptor M3target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 2target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 3target
DB00280DisopyramideSolute carrier family 22 member 2transporter
DB00280DisopyramideSolute carrier family 22 member 1transporter
DB00280DisopyramidePotassium voltage-gated channel subfamily H member 2target
DB00280DisopyramideAlpha-1-acid glycoprotein 2target
DB00280DisopyramideCytochrome P450 1A2enzyme
DB14600Edetate disodium anhydrousLeadtarget
DB14600Edetate disodium anhydrousIrontarget
DB14600Edetate disodium anhydrousManganese cationtarget
DB14600Edetate disodium anhydrousAdenosine deaminaseenzyme
DB14600Edetate disodium anhydrousSerum paraoxonase/lactonase 3enzyme
DB14600Edetate disodium anhydrousCytochrome P450 19A1enzyme
DB14600Edetate disodium anhydrousCytochrome P450 3A4enzyme
DB14600Edetate disodium anhydrousSerum paraoxonase/arylesterase 1enzyme
DB01064IsoprenalineBeta-1 adrenergic receptortarget
DB01064IsoprenalineBeta-2 adrenergic receptortarget
DB01064IsoprenalineBeta-3 adrenergic receptortarget
DB01064IsoprenalineCytochrome P450 1A1enzyme
DB01064IsoprenalineSuperoxide dismutase [Cu-Zn]target
DB01064IsoprenalineCytochrome P450 1B1enzyme
DB01064IsoprenalineSerum albumincarrier
DB01064IsoprenalineCatechol O-methyltransferaseenzyme
DB01064IsoprenalineCholinesteraseenzyme
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00379MexiletineSodium channel protein type 5 subunit alphatarget
DB00379MexiletineCytochrome P450 1A2enzyme
DB00379MexiletineCytochrome P450 2D6enzyme
DB00379MexiletineCytochrome P450 2B6enzyme
DB00379MexiletineCytochrome P450 2E1enzyme
DB00379MexiletineCytochrome P450 3A4enzyme
DB00379MexiletineAryl hydrocarbon receptortarget
DB01182PropafenoneSodium channel protein type 5 subunit alphatarget
DB01182PropafenonePotassium voltage-gated channel subfamily H member 2target
DB01182PropafenoneCytochrome P450 1A2enzyme
DB01182PropafenoneCytochrome P450 2D6enzyme
DB01182PropafenoneCytochrome P450 3A4enzyme
DB01182PropafenoneP-glycoprotein 1transporter
DB01182PropafenoneBeta-1 adrenergic receptortarget
DB01182PropafenoneBeta-2 adrenergic receptortarget
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB00908QuinidineSerum albumincarrier
DB00243RanolazineCytochrome P450 3A4enzyme
DB00243RanolazineCytochrome P450 2D6enzyme
DB00243RanolazineBile salt export pumptransporter
DB00243RanolazineP-glycoprotein 1transporter
DB00243RanolazineSodium channel proteintarget
DB00243RanolazineInward rectifier potassium channeltarget
DB00243RanolazineVoltage gated L-type calcium channeltarget
DB00243RanolazineAlpha-1 adrenergic receptorstarget
DB00243RanolazineBeta-1 adrenergic receptortarget
DB00243RanolazineFatty acidtarget
DB00243RanolazineAlpha-1-acid glycoprotein 1carrier
DB00243RanolazineMultidrug and toxin extrusion protein 1transporter
DB00243RanolazineMultidrug and toxin extrusion protein 2transporter
DrugDrug NamePhaseStatusCount
DB01118Amiodarone2Completed1
DB16012Celivarone2Completed1
DB12394Eleclazine2Completed1
DB01228Encainide2Completed1
DB01195Flecainide2Completed1
DB00458Imipramine2Completed1
DB00680Moricizine2Completed1
DB00264Metoprolol2 / 3Unknown Status1
DB00661Verapamil2 / 3Unknown Status1
DB01118Amiodarone3Recruiting1
DB01394Colchicine3Recruiting1
DB01228Encainide3Completed1
DB01195Flecainide3Completed1
DB00458Imipramine3Completed1
DB00379Mexiletine3Completed1
DB00680Moricizine3Completed1
DB01035Procainamide3Completed1
DB00908Quinidine3Completed1
DB00243Ranolazine3Completed1
DB00489Sotalol3Completed1
DB01118Amiodarone4Terminated1
DB01118Amiodarone4Unknown Status1
DB00281Lidocaine4Unknown Status1
DB00379Mexiletine4Terminated1
DB01035Procainamide4Terminated1
DB00489Sotalol4Recruiting1
DB00489Sotalol4Terminated1
DB00421Spironolactone4Completed1