Psychomotor Agitation

Also known as: Agitation, Psychomotor / Agitation,Psychomotor / Psychomotor restlessness / Agitated behavior / Psychomotor agitation (finding) / Psychomotor hyperactivity

Drug	Drug Name	Drug Description
DB12867	Benperidol	A neuroleptic butyrophenone derivative indicated in the treatment of psychoses, manic episodes, and psychomotor agitation.
DB12710	Perazine	A phenothiazine antipsychotic used in the acute and chronic treatment of psychotic disorders.
DB00420	Promazine	A phenothiazine used to manage schizophrenia.
DB12958	Prothipendyl	A neuroleptic agent indicated in the treatment of restlessness and agitation in patients with underlying psychiatric conditions.
DB04165	Valpromide	A valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder.

Drug	Drug Name	Target	Type
DB00420	Promazine	Dopamine D2 receptor	target
DB00420	Promazine	5-hydroxytryptamine receptor 2A	target
DB00420	Promazine	5-hydroxytryptamine receptor 2C	target
DB00420	Promazine	Alpha-1A adrenergic receptor	target
DB00420	Promazine	Muscarinic acetylcholine receptor M1	target
DB00420	Promazine	Histamine H1 receptor	target
DB00420	Promazine	Cytochrome P450 2C19	enzyme
DB00420	Promazine	Cytochrome P450 1A2	enzyme
DB00420	Promazine	Cytochrome P450 3A4	enzyme
DB00420	Promazine	Cytochrome P450 2C9	enzyme
DB00420	Promazine	Cytochrome P450 2D6	enzyme
DB04165	Valpromide	Limonene-1,2-epoxide hydrolase	target

Drug	Drug Name	Phase	Status	Count
DB09061	Cannabidiol	0	Recruiting	1
DB00633	Dexmedetomidine	1 / 2	Completed	1
DB00470	Dronabinol	2	Not Yet Recruiting	1
DB01156	Bupropion	2 / 3	Completed	1
DB01156	Bupropion	3	Enrolling by Invitation	1
DB00633	Dexmedetomidine	3	Active Not Recruiting	1
DB00633	Dexmedetomidine	3	Completed	1
DB00514	Dextromethorphan	3	Enrolling by Invitation	1
DB00502	Haloperidol	3	Completed	1
DB00408	Loxapine	3	Unknown Status	1
DB00313	Valproic acid	3	Completed	1
DB12537	1,2-Benzodiazepine	4	Completed	1
DB00575	Clonidine	4	Completed	1
DB00633	Dexmedetomidine	4	Recruiting	1
DB00633	Dexmedetomidine	4	Unknown Status	1
DB01175	Escitalopram	4	Completed	1
DB00502	Haloperidol	4	Terminated	1
DB01221	Ketamine	4	Completed	1
DB00186	Lorazepam	4	Terminated	1
DB00408	Loxapine	4	Terminated	1
DB00653	Magnesium sulfate	4	Completed	1
DB00184	Nicotine	4	Completed	1
DB00334	Olanzapine	4	Completed	1
DB01267	Paliperidone	4	Completed	1
DB01224	Quetiapine	4	Completed	1
DB00502	Haloperidol	Not Available	Completed	3
DB01221	Ketamine	Not Available	Completed	1
DB01221	Ketamine	Not Available	Unknown Status	1
DB00408	Loxapine	Not Available	Completed	2
DB00408	Loxapine	Not Available	Unknown Status	1
DB14009	Medical Cannabis	Not Available	Recruiting	1
DB00683	Midazolam	Not Available	Completed	3
DB00683	Midazolam	Not Available	Terminated	1
DB00334	Olanzapine	Not Available	Completed	2
DB00334	Olanzapine	Not Available	Terminated	1
DB00457	Prazosin	Not Available	Completed	1
DB01069	Promethazine	Not Available	Completed	1
DB00734	Risperidone	Not Available	Completed	1
DB00246	Ziprasidone	Not Available	Completed	3