Major Depressive Disorder (MDD)
Also known as: Major depressive disorder NOS / Major Depressive Disorder(MDD) / Depression - Major Depressive Disorder / MDD / Major Depressive Disorders / Disorder, Major Depressive / Major Depressive Disorder / Depressive Disorder, Major / Major Depression / Depression; Major Depressive Disorder / Depressive Disorder, Major Depressive Disorder / Major Depressive Disorder 1 / Depression NOS / Major depressive illness / Major depressive disorder (disorder) / Depressive disorder (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB00118 | Ademetionine | S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... |
| DB00321 | Amitriptyline | A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. |
| DB01238 | Aripiprazole | An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. |
| DB09128 | Brexpiprazole | A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. |
| DB01156 | Bupropion | A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. |
| DB00215 | Citalopram | A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. |
| DB06700 | Desvenlafaxine | An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. |
| DB00514 | Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| DB00476 | Duloxetine | A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. |
| DB01175 | Escitalopram | A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). |
| DB11823 | Esketamine | A NMDA receptor antagonist used for treatment-resistant depression. |
| DB00472 | Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| DB00176 | Fluvoxamine | A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. |
| DB12184 | Gepirone | A serotonin receptor agonist used to treat major depressive disorder in adults |
| DB08918 | Levomilnacipran | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults. |
| DB00934 | Maprotiline | A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression. |
| DB00370 | Mirtazapine | A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. |
| DB01171 | Moclobemide | A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. |
| DB00745 | Modafinil | A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. |
| DB00540 | Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
| DB00715 | Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| DB01224 | Quetiapine | A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. |
| DB00234 | Reboxetine | A drug used for the acute treatment of major depression and for maintenance therapy of depression. |
| DB01037 | Selegiline | A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. |
| DB01104 | Sertraline | A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. |
| DB09289 | Tianeptine | An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder. |
| DB00656 | Trazodone | A serotonin uptake inhibitor used to treat major depressive disorder. |
| DB00285 | Venlafaxine | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. |
| DB06684 | Vilazodone | An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. |
| DB09068 | Vortioxetine | A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). |