Critically Ill Patients

Also known as: Critically Ill Patient / Critically-ill / Critically Ill / Illness, Critical / Critical-Illness / Critical Illness / Critically-ill Patients

DrugDrug NameDrug Description
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB00213PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
DB01390Sodium bicarbonateA compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
DrugDrug NameTargetType
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleP-glycoprotein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier family 22 member 8transporter
DB00213PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DrugDrug NamePhaseStatusCount
DB09050Ceftolozane1Completed1
DB00803Colistin1Completed1
DB16523Deoxyribonuclease I1Active Not Recruiting1
DB00633Dexmedetomidine1Terminated1
DB00813Fentanyl1Terminated1
DB00130L-Glutamine1Terminated1
DB01606Tazobactam1Completed1
DB00512Vancomycin1Completed1
DB00638Inulin1 / 2Completed1
DB00333Methadone1 / 2Completed1
DB11158Pectin1 / 2Completed1
DB00020Sargramostim1 / 2Completed1
DB09322Zinc sulfate1 / 2Completed1
DB00316Acetaminophen2Completed1
DB00945Acetylsalicylic acid2Unknown Status1
DB00787Acyclovir2Completed1
DB00126Ascorbic acid2Completed2
DB00146Calcifediol2Completed1
DB00136Calcitriol2Completed1
DB01164Calcium chloride2Recruiting1
DB01327Cefazolin2Completed1
DB00537Ciprofloxacin2Completed1
DB04920Clevidipine2Terminated1
DB00758Clopidogrel2Unknown Status1
DB01914D-glucose2Completed1
DB06643Denosumab2Recruiting1
DB00016Erythropoietin2Completed1
DB00016Erythropoietin2Recruiting1
DB12466Favipiravir2Completed1
DB12725Felcisetrag2Terminated1
DB00687Fludrocortisone2Completed1
DB06716Fospropofol2Completed1
DB06716Fospropofol2Recruiting1
DB01004Ganciclovir2Completed1
DB01018Guanfacine2Recruiting1
DB00502Haloperidol2Completed1
DB01109Heparin2Completed1
DB01109Heparin2Recruiting1
DB00999Hydrochlorothiazide2Unknown Status1
DB00741Hydrocortisone2Completed1
DB00030Insulin human2Active Not Recruiting1
DB00030Insulin human2Completed2
DB15753Interferon Gamma2Active Not Recruiting1
DB00638Inulin2Active Not Recruiting1
DB00893Iron Dextran2Recruiting1
DB00130L-Glutamine2Unknown Status1
DB00583Levocarnitine2Terminated1
DB09407Magnesium chloride2Recruiting1
DB01065Melatonin2Recruiting1
DB00760Meropenem2Completed1
DB01233Metoclopramide2Terminated1
DB00916Metronidazole2Completed1
DB12598Nafamostat2Recruiting1
DB13169Nandrolone2Terminated1
DB00198Oseltamivir2Completed1
DB09140Oxygen2Active Not Recruiting1
DB00319Piperacillin2Completed1
DB00761Potassium chloride2Recruiting1
DB06209Prasugrel2Unknown Status1
DB00818Propofol2Completed1
DB00818Propofol2Recruiting2
DB00818Propofol2Terminated1
DB00899Remifentanil2Completed1
DB12404Remimazolam2Recruiting1
DB01098Rosuvastatin2Terminated1
DB01390Sodium bicarbonate2Recruiting1
DB09153Sodium chloride2Recruiting2
DB14502Sodium phosphate, dibasic2Recruiting1
DB01606Tazobactam2Completed1
DB00624Testosterone2Recruiting1
DB00152Thiamine2Completed2
DB08816Ticagrelor2Unknown Status1
DB00302Tranexamic acid2Terminated1
DB00577Valaciclovir2Completed1
DB01610Valganciclovir2Completed1
DB00399Zoledronic acid2Recruiting1
DB06151Acetylcysteine2 / 3Completed1
DB00126Ascorbic acid2 / 3Terminated1
DB00207Azithromycin2 / 3Not Yet Recruiting1
DB00169Cholecalciferol2 / 3Completed1
DB00169Cholecalciferol2 / 3Terminated1
DB00633Dexmedetomidine2 / 3Recruiting1
DB00292Etomidate2 / 3Completed1
DB00813Fentanyl2 / 3Unknown Status1
DB00099Filgrastim2 / 3Completed1
DB00741Hydrocortisone2 / 3Terminated1
DB01221Ketamine2 / 3Completed1
DB01221Ketamine2 / 3Terminated1
DB01221Ketamine2 / 3Unknown Status1
DB00130L-Glutamine2 / 3Terminated1
DB00186Lorazepam2 / 3Completed1
DB00683Midazolam2 / 3Completed1
DB00683Midazolam2 / 3Terminated1
DB00295Morphine2 / 3Terminated1
DB00818Propofol2 / 3Completed1
DB00421Spironolactone2 / 3Unknown Status1
DB00152Thiamine2 / 3Terminated1
DB00945Acetylsalicylic acid3Terminated1
DB00160Alanine3Active Not Recruiting1
DB00160Alanine3Completed2
DB11876Alanyl glutamine3Completed1
DB00125Arginine3Active Not Recruiting1
DB00125Arginine3Completed2
DB00126Ascorbic acid3Terminated1
DB00128Aspartic acid3Completed2
DB01164Calcium chloride3Active Not Recruiting1
DB01164Calcium chloride3Completed1
DB00493Cefotaxime3Completed1
DB01212Ceftriaxone3Completed1
DB00169Cholecalciferol3Completed2
DB00169Cholecalciferol3Recruiting1
DB00169Cholecalciferol3Unknown Status1
DB01597Cilastatin3Unknown Status1
DB00537Ciprofloxacin3Completed1
DB00565Cisatracurium3Completed1
DB00575Clonidine3Active Not Recruiting1
DB00575Clonidine3Completed1
DB00803Colistin3Completed1
DB01914D-glucose3Completed1
DB06779Dalteparin3Completed2
DB06292Dapagliflozin3Completed1
DB00633Dexmedetomidine3Active Not Recruiting1
DB00633Dexmedetomidine3Recruiting1
DB09341Dextrose, unspecified form3Active Not Recruiting1
DB13961Fish oil3Active Not Recruiting1
DB00695Furosemide3Terminated1
DB13180Gluconic Acid3Completed1
DB00142Glutamic acid3Completed2
DB00145Glycine3Active Not Recruiting1
DB00145Glycine3Completed2
DB00502Haloperidol3Terminated1
DB01109Heparin3Completed2
DB00117Histidine3Active Not Recruiting1
DB00117Histidine3Completed2
DB08818Hyaluronic acid3Unknown Status1
DB01598Imipenem3Unknown Status1
DB00030Insulin human3Active Not Recruiting1
DB00167Isoleucine3Active Not Recruiting1
DB00167Isoleucine3Completed2
DB01221Ketamine3Completed1
DB00130L-Glutamine3Completed3
DB00149Leucine3Active Not Recruiting1
DB00149Leucine3Completed2
DB00123Lysine3Active Not Recruiting1
DB00123Lysine3Completed2
DB09409Magnesium acetate tetrahydrate3Completed1
DB09407Magnesium chloride3Completed1
DB00653Magnesium sulfate3Active Not Recruiting1
DB13959Medium-chain triglycerides3Active Not Recruiting1
DB13959Medium-chain triglycerides3Completed1
DB00134Methionine3Active Not Recruiting1
DB00134Methionine3Completed2
DB00683Midazolam3Recruiting1
DB00683Midazolam3Unknown Status1
DB00211Midodrine3Completed1
DB09049Naloxegol3Withdrawn1
DB12293Nefopam3Recruiting1
DB00368Norepinephrine3Not Yet Recruiting1
DB00646Nystatin3Completed1
DB09567Olive oil3Active Not Recruiting1
DB14556Peracetic acid3Completed1
DB00120Phenylalanine3Active Not Recruiting1
DB00120Phenylalanine3Completed2
DB09287Polyethylene glycol3Withdrawn1
DB00781Polymyxin B3Unknown Status1
DB14498Potassium acetate3Completed1
DB00761Potassium chloride3Active Not Recruiting1
DB00761Potassium chloride3Completed1
DB00172Proline3Active Not Recruiting1
DB00172Proline3Completed2
DB00818Propofol3Active Not Recruiting1
DB00571Propranolol3Completed1
DB06480Prucalopride3Unknown Status1
DB00412Rosiglitazone3Unknown Status1
DB11135Selenium3Terminated1
DB00133Serine3Active Not Recruiting1
DB00133Serine3Completed2
DB00641Simvastatin3Completed1
DB09395Sodium acetate3Active Not Recruiting1
DB09395Sodium acetate3Completed2
DB09153Sodium chloride3Completed2
DB09153Sodium chloride3Terminated1
DB09561Sodium glycerophosphate3Active Not Recruiting1
DB11151Sodium hydroxide3Completed1
DB09449Sodium phosphate, monobasic3Completed1
DB09422Soybean oil3Active Not Recruiting1
DB09422Soybean oil3Completed1
DB01956Taurine3Active Not Recruiting1
DB00152Thiamine3Terminated1
DB00156Threonine3Active Not Recruiting1
DB00156Threonine3Completed2
DB00684Tobramycin3Completed1
DB00150Tryptophan3Active Not Recruiting1
DB00150Tryptophan3Completed2
DB00135Tyrosine3Active Not Recruiting1
DB00135Tyrosine3Completed1
DB00161Valine3Active Not Recruiting1
DB00161Valine3Completed2
DB11094Vitamin D3Completed1
DB11094Vitamin D3Unknown Status1
DB00163Vitamin E3Terminated1
DB01593Zinc3Terminated1
DB14487Zinc acetate3Completed1
DB09322Zinc sulfate3Active Not Recruiting1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Terminated1
DB00160Alanine4Active Not Recruiting1
DB00160Alanine4Terminated1
DB00062Albumin human4Recruiting1
DB06742Ambroxol4Completed1
DB00125Arginine4Active Not Recruiting1
DB00125Arginine4Completed1
DB00125Arginine4Terminated1
DB00126Ascorbic acid4Terminated1
DB01164Calcium chloride4Active Not Recruiting1
DB01164Calcium chloride4Terminated1
DB00520Caspofungin4Completed1
DB00493Cefotaxime4Completed1
DB01212Ceftriaxone4Recruiting1
DB14547Chloride ion4Unknown Status1
DB00169Cholecalciferol4Completed1
DB01597Cilastatin4Enrolling by Invitation1
DB00537Ciprofloxacin4Recruiting1
DB00565Cisatracurium4Completed1
DB00575Clonidine4Completed1
DB00575Clonidine4Recruiting1
DB00803Colistin4Recruiting1
DB00080Daptomycin4Completed1
DB00633Dexmedetomidine4Completed2
DB00633Dexmedetomidine4Recruiting1
DB00633Dexmedetomidine4Terminated2
DB00633Dexmedetomidine4Withdrawn1
DB09341Dextrose, unspecified form4Active Not Recruiting1
DB09341Dextrose, unspecified form4Terminated1
DB11823Esketamine4Recruiting1
DB00736Esomeprazole4Completed1
DB00813Fentanyl4Completed2
DB00813Fentanyl4Recruiting1
DB00813Fentanyl4Terminated1
DB00813Fentanyl4Withdrawn1
DB13961Fish oil4Terminated1
DB00695Furosemide4Terminated1
DB00145Glycine4Active Not Recruiting1
DB00145Glycine4Terminated1
DB00117Histidine4Active Not Recruiting1
DB00117Histidine4Terminated1
DB00741Hydrocortisone4Terminated1
DB01598Imipenem4Enrolling by Invitation1
DB01598Imipenem4Recruiting1
DB00167Isoleucine4Active Not Recruiting1
DB00167Isoleucine4Terminated1
DB01221Ketamine4Active Not Recruiting1
DB12465Ketanserin4Unknown Status1
DB16555Lactoferrin4Not Yet Recruiting1
DB00149Leucine4Active Not Recruiting1
DB00149Leucine4Terminated1
DB01137Levofloxacin4Completed1
DB00281Lidocaine4Unknown Status1
DB00601Linezolid4Recruiting1
DB00123Lysine4Active Not Recruiting1
DB00123Lysine4Terminated1
DB00653Magnesium sulfate4Recruiting1
DB00653Magnesium sulfate4Terminated1
DB13959Medium-chain triglycerides4Terminated1
DB01065Melatonin4Completed1
DB00760Meropenem4Completed1
DB00134Methionine4Active Not Recruiting1
DB00134Methionine4Terminated1
DB01233Metoclopramide4Terminated1
DB14158Microcrystalline cellulose4Completed1
DB00683Midazolam4Completed1
DB00683Midazolam4Recruiting1
DB00683Midazolam4Terminated2
DB00683Midazolam4Unknown Status1
DB00211Midodrine4Completed1
DB08813Nadroparin4Completed1
DB09152Nitrogen4Terminated1
DB00368Norepinephrine4Terminated1
DB00646Nystatin4Completed1
DB09567Olive oil4Terminated1
DB11133Omega-3 fatty acids4Terminated1
DB00497Oxycodone4Completed1
DB09140Oxygen4Recruiting1
DB00213Pantoprazole4Completed1
DB00120Phenylalanine4Active Not Recruiting1
DB00120Phenylalanine4Terminated1
DB00388Phenylephrine4Terminated1
DB14500Potassium4Completed1
DB00761Potassium chloride4Completed1
DB00761Potassium chloride4Terminated1
DB00172Proline4Active Not Recruiting1
DB00172Proline4Terminated1
DB00818Propofol4Completed1
DB00818Propofol4Terminated2
DB00863Ranitidine4Completed1
DB12377Relebactam4Enrolling by Invitation1
DB00899Remifentanil4Unknown Status1
DB11127Selenious acid4Completed1
DB00133Serine4Terminated1
DB09395Sodium acetate4Terminated1
DB09153Sodium chloride4Completed1
DB09153Sodium chloride4Terminated1
DB09561Sodium glycerophosphate4Terminated1
DB09422Soybean oil4Terminated1
DB01956Taurine4Terminated1
DB00152Thiamine4Terminated1
DB00156Threonine4Active Not Recruiting1
DB00156Threonine4Terminated1
DB00150Tryptophan4Active Not Recruiting1
DB00150Tryptophan4Terminated1
DB00135Tyrosine4Active Not Recruiting1
DB00135Tyrosine4Terminated1
DB00161Valine4Active Not Recruiting1
DB00161Valine4Terminated1
DB11094Vitamin D4Completed1
DB09322Zinc sulfate4Terminated1
DB00316AcetaminophenNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB09393Amino acidsNot AvailableRecruiting1
DB09393Amino acidsNot AvailableSuspended1
DB09060AvibactamNot AvailableUnknown Status1
DB00201CaffeineNot AvailableRecruiting1
DB15941CasirivimabNot AvailableCompleted1
DB00520CaspofunginNot AvailableCompleted2
DB00493CefotaximeNot AvailableRecruiting1
DB00438CeftazidimeNot AvailableUnknown Status1
DB01212CeftriaxoneNot AvailableRecruiting1
DB01112CefuroximeNot AvailableRecruiting1
DB16599CerebrolysinNot AvailableEnrolling by Invitation1
DB01597CilastatinNot AvailableUnknown Status1
DB00565CisatracuriumNot AvailableRecruiting1
DB04272Citric acidNot AvailableCompleted1
DB01914D-glucoseNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableRecruiting1
DB09341Dextrose, unspecified formNot AvailableTerminated1
DB01225EnoxaparinNot AvailableCompleted1
DB00813FentanylNot AvailableRecruiting1
DB13423Ferric hydroxideNot AvailableCompleted1
DB00695FurosemideNot AvailableTerminated1
DB00996GabapentinNot AvailableCompleted1
DB00986GlycopyrroniumNot AvailableUnknown Status1
DB01109HeparinNot AvailableCompleted1
DB15940ImdevimabNot AvailableCompleted1
DB01598ImipenemNot AvailableUnknown Status1
DB01306Insulin aspartNot AvailableCompleted1
DB09564Insulin degludecNot AvailableNot Yet Recruiting1
DB00047Insulin glargineNot AvailableNot Yet Recruiting1
DB00030Insulin humanNot AvailableCompleted3
DB00030Insulin humanNot AvailableNot Yet Recruiting1
DB00030Insulin humanNot AvailableRecruiting1
DB00030Insulin humanNot AvailableTerminated1
DB01362IohexolNot AvailableRecruiting1
DB01592IronNot AvailableCompleted1
DB09146Iron sucroseNot AvailableCompleted1
DB04924ItoprideNot AvailableUnknown Status1
DB15823Lactobacillus acidophilusNot AvailableCompleted1
DB16540Lactobacillus delbrueckii bulgaricusNot AvailableCompleted1
DB00601LinezolidNot AvailableCompleted1
DB13872LormetazepamNot AvailableCompleted1
DB14123MentholNot AvailableRecruiting1
DB00760MeropenemNot AvailableCompleted3
DB00760MeropenemNot AvailableUnknown Status1
DB00333MethadoneNot AvailableRecruiting1
DB01233MetoclopramideNot AvailableUnknown Status1
DB00683MidazolamNot AvailableCompleted2
DB00683MidazolamNot AvailableRecruiting1
DB00235MilrinoneNot AvailableRecruiting1
DB00745ModafinilNot AvailableCompleted1
DB00295MorphineNot AvailableCompleted1
DB01400NeostigmineNot AvailableNot Yet Recruiting1
DB01400NeostigmineNot AvailableUnknown Status1
DB00646NystatinNot AvailableRecruiting1
DB00338OmeprazoleNot AvailableCompleted1
DB00497OxycodoneNot AvailableCompleted1
DB09140OxygenNot AvailableCompleted1
DB00319PiperacillinNot AvailableCompleted3
DB00781Polymyxin BNot AvailableRecruiting1
DB00818PropofolNot AvailableCompleted2
DB00818PropofolNot AvailableRecruiting1
DB14761RemdesivirNot AvailableCompleted1
DB00728RocuroniumNot AvailableCompleted1
DB00728RocuroniumNot AvailableUnknown Status1
DB09036SiltuximabNot AvailableRecruiting1
DB09153Sodium chlorideNot AvailableRecruiting1
DB02772SucroseNot AvailableCompleted1
DB06206SugammadexNot AvailableNot Yet Recruiting1
DB06206SugammadexNot AvailableUnknown Status1
DB01606TazobactamNot AvailableCompleted2
DB00560TigecyclineNot AvailableUnknown Status1
DB06273TocilizumabNot AvailableCompleted2
DB06273TocilizumabNot AvailableRecruiting1
DB12038UlinastatinNot AvailableCompleted1
DB00512VancomycinNot AvailableCompleted2
DB00512VancomycinNot AvailableRecruiting1