Hypogonadotrophic Hypogonadism

Also known as: Hypogonadotropic Hypogonadism / Kallman syndrome / Fertile eunuch syndrome / Secondary hypogonadism / Gonadotrophin deficiency

Drug	Drug Name	Drug Description
DB00624	Testosterone	A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
DB13943	Testosterone cypionate	An androgen used to treat low or absent testosterone.

Drug	Drug Name	Target	Type
DB00624	Testosterone	Androgen receptor	target
DB00624	Testosterone	Cytochrome P450 3A4	enzyme
DB00624	Testosterone	Cytochrome P450 19A1	enzyme
DB00624	Testosterone	Amine oxidase [flavin-containing] A	enzyme
DB00624	Testosterone	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
DB00624	Testosterone	Serum albumin	carrier
DB00624	Testosterone	Sex hormone-binding globulin	carrier
DB00624	Testosterone	Cytochrome P450 3A5	enzyme
DB00624	Testosterone	Cytochrome P450 3A7	enzyme
DB00624	Testosterone	Solute carrier family 22 member 8	transporter
DB00624	Testosterone	Solute carrier family 22 member 7	transporter
DB00624	Testosterone	Sodium/bile acid cotransporter	transporter
DB00624	Testosterone	ATP-binding cassette sub-family G member 2	transporter
DB00624	Testosterone	Cytochrome P450 1A1	enzyme
DB00624	Testosterone	Cytochrome P450 1B1	enzyme
DB00624	Testosterone	Cytochrome P450 2A13	enzyme
DB00624	Testosterone	Cytochrome P450 2B6	enzyme
DB00624	Testosterone	Cytochrome P450 2C19	enzyme
DB00624	Testosterone	Cytochrome P450 2C8	enzyme
DB00624	Testosterone	Cytochrome P450 2C9	enzyme
DB00624	Testosterone	Cytochrome P450 3A43	enzyme
DB00624	Testosterone	Estrogen receptor alpha	target
DB00624	Testosterone	Mineralocorticoid receptor	target
DB00624	Testosterone	Solute carrier organic anion transporter family member 1B3	transporter
DB13943	Testosterone cypionate	Androgen receptor	target
DB13943	Testosterone cypionate	Cytochrome P450 3A4	enzyme
DB13943	Testosterone cypionate	Amine oxidase [flavin-containing] A	enzyme
DB13943	Testosterone cypionate	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
DB13943	Testosterone cypionate	Serum albumin	carrier
DB13943	Testosterone cypionate	Sex hormone-binding globulin	carrier
DB13943	Testosterone cypionate	Cytochrome P450 3A5	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 3A7	enzyme
DB13943	Testosterone cypionate	Solute carrier organic anion transporter family member 1A2	transporter
DB13943	Testosterone cypionate	Solute carrier family 22 member 8	transporter
DB13943	Testosterone cypionate	Solute carrier family 22 member 7	transporter
DB13943	Testosterone cypionate	P-glycoprotein 1	transporter
DB13943	Testosterone cypionate	Sodium/bile acid cotransporter	transporter
DB13943	Testosterone cypionate	Solute carrier family 22 member 3	transporter
DB13943	Testosterone cypionate	Solute carrier family 22 member 4	transporter
DB13943	Testosterone cypionate	ATP-binding cassette sub-family G member 2	transporter
DB13943	Testosterone cypionate	Cytochrome P450 1A1	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 2A13	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 2B6	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 2C19	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 2C8	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 2C9	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 3A43	enzyme
DB13943	Testosterone cypionate	Estrogen receptor alpha	target
DB13943	Testosterone cypionate	Mineralocorticoid receptor	target
DB13943	Testosterone cypionate	3-oxo-5-alpha-steroid 4-dehydrogenase	enzyme
DB13943	Testosterone cypionate	Cytochrome P450 19A1	enzyme

Drug	Drug Name	Phase	Status	Count
DB01006	Letrozole	3	Completed	1
DB00624	Testosterone	4	Completed	2