Acute Coronary Syndrome (ACS)

Also known as: Acute Coronary Syndome / Actue Coronary Syndrome / Coronary Syndrome, Acute / ACS / Coronary Acute Syndrome / Acute Coronary Syndromes / Acute Coronary Syndrome / Acute coronary syndrome (disorder)

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB01225EnoxaparinA low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction.
DB00063EptifibatideA peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention.
DB08816TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00945Acetylsalicylic acidSialidase-1target
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB00758ClopidogrelSerum albumincarrier
DB01225EnoxaparinAntithrombin-IIItarget
DB01225EnoxaparinCoagulation factor Xtarget
DB01225EnoxaparinMyeloperoxidaseenzyme
DB01225EnoxaparinProthrombintarget
DB00063EptifibatideIntegrin beta-3target
DB00063EptifibatideVoltage-dependent N-type calcium channeltarget
DB08816TicagrelorCytochrome P450 3A4enzyme
DB08816TicagrelorP2Y purinoceptor 12target
DB08816TicagrelorP-glycoprotein 1transporter
DB08816TicagrelorCytochrome P450 2C9enzyme
DB08816TicagrelorSerum albumincarrier
DB08816TicagrelorCytochrome P450 3A5enzyme
DB08816TicagrelorCytochrome P450 2B6enzyme
DrugDrug NamePhaseStatusCount
DB00907Cocaine0Completed1
DB00633Dexmedetomidine0Completed1
DB05227APD7911Terminated2
DB00945Acetylsalicylic acid1Completed3
DB00945Acetylsalicylic acid1Terminated2
DB06605Apixaban1Completed1
DB01076Atorvastatin1Completed2
DB15047BMS-9193731Completed1
DB00758Clopidogrel1Completed3
DB00758Clopidogrel1Terminated3
DB01225Enoxaparin1Completed2
DB12270Losmapimod1Completed2
DB00218Moxifloxacin1Completed1
DB00213Pantoprazole1Completed1
DB06209Prasugrel1Terminated1
DB01098Rosuvastatin1Completed2
DB01104Sertraline1Terminated1
DB00641Simvastatin1Terminated1
DB08816Ticagrelor1Completed3
DB10803Typhoid Vi polysaccharide vaccine1Completed1
DB16349Vicagrel1Completed2
DB05692Vorapaxar1Completed1
DB00404Alprazolam1 / 2Recruiting1
DB12000Apabetalone1 / 2Completed1
DB01156Bupropion1 / 2Completed1
DB00215Citalopram1 / 2Completed1
DB00215Citalopram1 / 2Withdrawn1
DB01590Everolimus1 / 2Completed1
DB01104Sertraline1 / 2Completed1
DB09499Thiosulfuric acid1 / 2Completed1
DB0581099mTc-glucarate2Completed1
DB05631ALT-20742Completed1
DB00945Acetylsalicylic acid2Completed2
DB00945Acetylsalicylic acid2Recruiting2
DB00041Aldesleukin2Recruiting1
DB09302Alirocumab2Completed1
DB06605Apixaban2Completed1
DB06605Apixaban2Terminated1
DB12046Atopaxar2Completed2
DB01076Atorvastatin2Completed1
DB12758Atreleuton2Completed1
DB00612Bisoprolol2Completed2
DB18538CER-0012Completed2
DB06441Cangrelor2Completed1
DB00758Clopidogrel2Completed8
DB00758Clopidogrel2Recruiting2
DB01394Colchicine2Recruiting2
DB12289Darexaban2Completed1
DB00063Eptifibatide2Completed3
DB09303Evolocumab2Active Not Recruiting2
DB04945Hemoglobin2Completed1
DB01109Heparin2Completed1
DB05683Iodofiltic acid I-1232Completed1
DB11984Letaxaban2Completed1
DB00583Levocarnitine2Completed1
DB00722Lisinopril2Unknown Status1
DB12270Losmapimod2Completed1
DB00264Metoprolol2Unknown Status1
DB11839PZ-1282Completed1
DB00761Potassium chloride2Completed1
DB11090Potassium nitrate2Completed1
DB06209Prasugrel2Completed3
DB00243Ranolazine2Terminated1
DB06228Rivaroxaban2Completed2
DB06228Rivaroxaban2Recruiting1
DB08816Ticagrelor2Completed5
DB00775Tirofiban2Completed1
DB12310Trehalose2Unknown Status1
DB05737Varespladib methyl2Completed1
DB12164Varespladib methyl2Completed1
DB00758Clopidogrel2 / 3Completed1
DB01394Colchicine2 / 3Completed1
DB01065Melatonin2 / 3Completed1
DB00806Pentoxifylline2 / 3Completed1
DB06209Prasugrel2 / 3Completed1
DB08816Ticagrelor2 / 3Completed1
DB00945Acetylsalicylic acid3Completed3
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Terminated2
DB06203Alogliptin3Completed1
DB06605Apixaban3Terminated1
DB01076Atorvastatin3Completed3
DB01076Atorvastatin3Terminated1
DB00006Bivalirudin3Completed2
DB01156Bupropion3Completed1
DB06441Cangrelor3Completed1
DB06441Cangrelor3Terminated2
DB04540Cholesterol3Recruiting1
DB00758Clopidogrel3Completed15
DB00758Clopidogrel3Recruiting1
DB00758Clopidogrel3Terminated3
DB00758Clopidogrel3Unknown Status1
DB01394Colchicine3Completed1
DB00151Cysteine3Unknown Status1
DB12181Dalcetrapib3Completed1
DB12181Dalcetrapib3Recruiting1
DB06311Darapladib3Completed1
DB00063Eptifibatide3Completed2
DB09303Evolocumab3Completed1
DB11728Fondaparinux3Completed1
DB01109Heparin3Completed4
DB14901Inclisiran3Recruiting1
DB00030Insulin human3Completed1
DB09265Lixisenatide3Completed1
DB12270Losmapimod3Completed1
DB00331Metformin3Recruiting1
DB16233Milvexian3Recruiting1
DB00184Nicotine3Recruiting1
DB00338Omeprazole3Terminated1
DB06635Otamixaban3Completed1
DB09140Oxygen3Completed2
DB06209Prasugrel3Completed12
DB06228Rivaroxaban3Active Not Recruiting1
DB06228Rivaroxaban3Completed1
DB01098Rosuvastatin3Completed2
DB00641Simvastatin3Completed1
DB08816Ticagrelor3Active Not Recruiting1
DB04902Ticagrelor3Completed2
DB08816Ticagrelor3Completed7
DB08816Ticagrelor3Not Yet Recruiting1
DB08816Ticagrelor3Recruiting1
DB08816Ticagrelor3Terminated1
DB08816Ticagrelor3Unknown Status2
DB00775Tirofiban3Completed1
DB00775Tirofiban3Withdrawn1
DB01273Varenicline3Completed1
DB01273Varenicline3Recruiting1
DB05737Varespladib methyl3Terminated1
DB16346Veliflapon3Suspended1
DB00163Vitamin E3Unknown Status1
DB00054Abciximab4Completed1
DB00284Acarbose4Completed1
DB00316Acetaminophen4Completed1
DB00945Acetylsalicylic acid4Active Not Recruiting2
DB00945Acetylsalicylic acid4Completed15
DB00945Acetylsalicylic acid4Not Yet Recruiting1
DB00945Acetylsalicylic acid4Recruiting7
DB00945Acetylsalicylic acid4Terminated1
DB00945Acetylsalicylic acid4Unknown Status2
DB00640Adenosine4Completed1
DB09302Alirocumab4Completed1
DB00437Allopurinol4Completed1
DB01060Amoxicillin4Not Yet Recruiting1
DB11598Antithrombin III human4Unknown Status1
DB06605Apixaban4Completed1
DB01076Atorvastatin4Completed8
DB01076Atorvastatin4Unknown Status1
DB01393Bezafibrate4Completed1
DB00006Bivalirudin4Completed2
DB00006Bivalirudin4Unknown Status2
DB01373Calcium4Unknown Status1
DB06441Cangrelor4Completed3
DB06441Cangrelor4Unknown Status2
DB01136Carvedilol4Completed1
DB01166Cilostazol4Completed3
DB00215Citalopram4Terminated1
DB00758Clopidogrel4Completed21
DB00758Clopidogrel4Not Yet Recruiting1
DB00758Clopidogrel4Recruiting6
DB00758Clopidogrel4Terminated3
DB00758Clopidogrel4Unknown Status11
DB00758Clopidogrel4Withdrawn2
DB01394Colchicine4Completed2
DB01394Colchicine4Recruiting1
DB01394Colchicine4Unknown Status1
DB14726Dabigatran4Completed1
DB14726Dabigatran4Recruiting1
DB14726Dabigatran4Terminated1
DB00343Diltiazem4Completed1
DB00841Dobutamine4Completed1
DB01225Enoxaparin4Completed5
DB00668Epinephrine4Completed1
DB01175Escitalopram4Completed1
DB00187Esmolol4Unknown Status1
DB00736Esomeprazole4Completed2
DB00402Eszopiclone4Completed1
DB09303Evolocumab4Recruiting2
DB01276Exenatide4Completed1
DB00973Ezetimibe4Completed3
DB00927Famotidine4Completed2
DB01039Fenofibrate4Completed1
DB01039Fenofibrate4Unknown Status1
DB00569Fondaparinux4Completed1
DB01109Heparin4Completed2
DB01109Heparin4Unknown Status1
DB01611Hydroxychloroquine4Completed1
DB00030Insulin human4Completed1
DB00030Insulin human4Suspended1
DB09083Ivabradine4Completed1
DB06725Lornoxicam4Completed1
DB00331Metformin4Unknown Status1
DB00264Metoprolol4Completed2
DB00235Milrinone4Completed1
DB00471Montelukast4Terminated1
DB00295Morphine4Completed2
DB00622Nicardipine4Unknown Status1
DB06690Nitrous oxide4Completed1
DB00338Omeprazole4Unknown Status1
DB09140Oxygen4Completed1
DB00213Pantoprazole4Not Yet Recruiting1
DB00213Pantoprazole4Unknown Status1
DB00946Phenprocoumon4Completed1
DB00946Phenprocoumon4Terminated1
DB01022Phylloquinone4Completed1
DB14500Potassium4Completed1
DB06209Prasugrel4Completed16
DB06209Prasugrel4Recruiting4
DB06209Prasugrel4Terminated3
DB06209Prasugrel4Unknown Status5
DB00175Pravastatin4Completed3
DB00178Ramipril4Unknown Status1
DB06228Rivaroxaban4Completed2
DB06228Rivaroxaban4Not Yet Recruiting1
DB06228Rivaroxaban4Recruiting2
DB06228Rivaroxaban4Unknown Status2
DB01098Rosuvastatin4Completed5
DB01098Rosuvastatin4Unknown Status3
DB00641Simvastatin4Completed1
DB00641Simvastatin4Unknown Status1
DB01261Sitagliptin4Unknown Status1
DB00086Streptokinase4Completed1
DB00966Telmisartan4Unknown Status1
DB00031Tenecteplase4Unknown Status1
DB08816Ticagrelor4Completed24
DB08816Ticagrelor4Recruiting10
DB08816Ticagrelor4Terminated1
DB08816Ticagrelor4Unknown Status13
DB08816Ticagrelor4Withdrawn3
DB00775Tirofiban4Completed1
DB00775Tirofiban4Unknown Status1
DB01273Varenicline4Unknown Status1
DB11094Vitamin D4Unknown Status1
DB11739Vonoprazan4Not Yet Recruiting1
DB00682Warfarin4Recruiting1
DB00425Zolpidem4Unknown Status1
DB00945Acetylsalicylic acidNot AvailableActive Not Recruiting1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00945Acetylsalicylic acidNot AvailableRecruiting1
DB00945Acetylsalicylic acidNot AvailableTerminated1
DB00945Acetylsalicylic acidNot AvailableWithdrawn1
DB09302AlirocumabNot AvailableNot Yet Recruiting1
DB09302AlirocumabNot AvailableRecruiting1
DB09302AlirocumabNot AvailableUnknown Status1
DB00009AlteplaseNot AvailableWithdrawn1
DB01076AtorvastatinNot AvailableUnknown Status2
DB00612BisoprololNot AvailableCompleted1
DB01156BupropionNot AvailableCompleted1
DB00796Candesartan cilexetilNot AvailableTerminated1
DB04540CholesterolNot AvailableNot Yet Recruiting1
DB00758ClopidogrelNot AvailableCompleted7
DB00758ClopidogrelNot AvailableUnknown Status3
DB00758ClopidogrelNot AvailableWithdrawn1
DB01394ColchicineNot AvailableNot Yet Recruiting1
DB06779DalteparinNot AvailableCompleted1
DB01225EnoxaparinNot AvailableWithdrawn1
DB09303EvolocumabNot AvailableNot Yet Recruiting1
DB09303EvolocumabNot AvailableRecruiting1
DB09303EvolocumabNot AvailableUnknown Status1
DB00973EzetimibeNot AvailableRecruiting1
DB00973EzetimibeNot AvailableUnknown Status1
DB11728FondaparinuxNot AvailableCompleted1
DB01109HeparinNot AvailableCompleted1
DB00883Isosorbide dinitrateNot AvailableCompleted1
DB00264MetoprololNot AvailableUnknown Status1
DB00184NicotineNot AvailableCompleted2
DB16284PelacarsenNot AvailableWithdrawn1
DB06209PrasugrelNot AvailableCompleted2
DB06209PrasugrelNot AvailableUnknown Status1
DB00178RamiprilNot AvailableCompleted1
DB06228RivaroxabanNot AvailableCompleted4
DB06228RivaroxabanNot AvailableRecruiting1
DB01098RosuvastatinNot AvailableCompleted1
DB01098RosuvastatinNot AvailableUnknown Status2
DB01104SertralineNot AvailableCompleted1
DB00641SimvastatinNot AvailableUnknown Status1
DB01323St. John's WortNot AvailableWithdrawn1
DB00086StreptokinaseNot AvailableWithdrawn1
DB16336TafolecimabNot AvailableNot Yet Recruiting1
DB00966TelmisartanNot AvailableTerminated1
DB08816TicagrelorNot AvailableActive Not Recruiting1
DB08816TicagrelorNot AvailableCompleted12
DB08816TicagrelorNot AvailableRecruiting1
DB08816TicagrelorNot AvailableUnknown Status4
DB00775TirofibanNot AvailableTerminated1
DB01273VareniclineNot AvailableUnknown Status1
DB00682WarfarinNot AvailableCompleted1